scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1007787178 |
P356 | DOI | 10.1038/SJ.ONC.1202672 |
P698 | PubMed publication ID | 10391678 |
P5875 | ResearchGate publication ID | 12906907 |
P2093 | author name string | S K Shore | |
A Y Tsygankov | |||
E A Feshchenko | |||
P2860 | cites work | C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins | Q24305258 |
Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G | Q24309656 | ||
The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner | Q24310761 | ||
Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation | Q24336399 | ||
A ras-related gene with transformation suppressor activity | Q24338921 | ||
Activation of murine c-abl protooncogene: effect of a point mutation on oncogenic activation | Q24557464 | ||
Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity | Q24645473 | ||
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras | Q28238120 | ||
A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions | Q28261445 | ||
Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases | Q28267092 | ||
A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells | Q28289338 | ||
Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl | Q28294930 | ||
B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins | Q28298373 | ||
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate | Q28301966 | ||
Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes | Q28585310 | ||
The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells | Q28609032 | ||
Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase | Q28609041 | ||
Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells | Q28609046 | ||
p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase | Q28610005 | ||
Production of high-titer helper-free retroviruses by transient transfection | Q29547802 | ||
Integrins and signal transduction pathways: the road taken | Q29547895 | ||
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling | Q29616451 | ||
c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor | Q29618661 | ||
Oncogenic forms of Cbl abrogate the anchorage requirement but not the growth factor requirement for proliferation | Q30176121 | ||
Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein | Q30176216 | ||
EGF receptor binding and transformation by v-cbl is ablated by the introduction of a loss-of-function mutation from the Caenorhabditis elegans sli-1 gene | Q30176545 | ||
Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins | Q30176934 | ||
Interactions of Cbl with two adapter proteins, Grb2 and Crk, upon T cell activation | Q30177028 | ||
Coupling of the Proto-oncogene Product c-Cbl to the Epidermal Growth Factor Receptor | Q30192999 | ||
Crkl is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia | Q30193124 | ||
Similarity of sli-1 , a Regulator of Vulval Development in C. elegans , to the Mammalian Proto-Oncogene c- cbl | Q30193172 | ||
T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38. | Q30193176 | ||
The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase | Q30193184 | ||
The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase | Q30193228 | ||
Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells | Q30193317 | ||
Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc gamma receptors | Q30193495 | ||
The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha | Q36164471 | ||
Oct-1 protein promotes functional transcription complex assembly on the mouse mammary tumor virus promoter | Q38289112 | ||
A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration | Q38334944 | ||
An ELISA for detection of apoptosis | Q39718998 | ||
A transient three-plasmid expression system for the production of high titer retroviral vectors | Q40393091 | ||
Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. | Q41075804 | ||
The selective protein kinase C inhibitor, Ro-31-8220, inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression, and activates Jun N-terminal kinase | Q41157362 | ||
Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanism | Q41168715 | ||
Signaling through focal adhesion kinase | Q41359146 | ||
Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. | Q41966849 | ||
Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells. | Q42528757 | ||
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway | Q42618265 | ||
The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C. | Q42802927 | ||
Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways | Q42807426 | ||
The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway. | Q45989111 | ||
Regulation of beta 1-integrin-mediated cell adhesion by the Cbl adaptor protein | Q47849795 | ||
Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2 | Q57754194 | ||
Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells | Q71742747 | ||
Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways | Q72315745 | ||
Mutational analysis of the role of Rap1 in regulating cytoskeletal function in Dictyostelium | Q73190501 | ||
The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase | Q73224118 | ||
Phosphatidylinositol-3 kinase is involved in ruffled border formation in osteoclasts | Q73589789 | ||
Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion | Q74037504 | ||
Phosphatidylinositol 3-kinase association with the osteoclast cytoskeleton, and its involvement in osteoclast attachment and spreading | Q74062887 | ||
P433 | issue | 25 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 3703-3715 | |
P577 | publication date | 1999-06-01 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts | |
P478 | volume | 18 |
Q35317826 | Abrogation of Cbl-PI3K interaction increases bone formation and osteoblast proliferation |
Q43511394 | Activation of Rho is required for ligand-independent oncogenic signaling by a mutant epidermal growth factor receptor |
Q37460098 | An essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn. |
Q34405560 | Beyond the RING: CBL proteins as multivalent adapters |
Q41999037 | CD93 and dystroglycan cooperation in human endothelial cell adhesion and migration adhesion and migration |
Q33292321 | Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl |
Q38038873 | Cbl proteins in platelet activation |
Q36138338 | Cbl-3-deficient mice exhibit normal epithelial development |
Q38112644 | Cbl-family proteins as regulators of cytoskeleton-dependent phenomena |
Q34764852 | Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion |
Q34205572 | Cbl: many adaptations to regulate protein tyrosine kinases |
Q40874616 | IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation |
Q33784584 | Interaction of c-Cbl with myosin IIA regulates Bleb associated macropinocytosis of Kaposi's sarcoma-associated herpesvirus |
Q36252532 | Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b |
Q34111708 | Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy |
Q36203705 | Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation. |
Q80586970 | Loss of c-abl facilitates anchorage-independent growth of p53- and RB- deficient primary mouse embryonic fibroblasts |
Q28207560 | Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation |
Q36585134 | Molecular regulation of osteoclast activity |
Q64059948 | PI3K activation increases SDF-1 production and number of osteoclast precursors, and enhances SDF-1-mediated osteoclast precursor migration |
Q32138771 | RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation |
Q33211646 | Rapid ubiquitination of Syk following GPVI activation in platelets |
Q40601255 | Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells |
Q35783339 | Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair |
Q38348572 | Selectins and anti-CD15 (Lewis x/a) antibodies transmit activation signals in Hodgkin's lymphoma–derived cell lines |
Q34299184 | The Loss of Cbl-Phosphatidylinositol 3-Kinase Interaction Perturbs RANKL-mediated Signaling, Inhibiting Bone Resorption and Promoting Osteoclast Survival |
Q46476342 | The multidomain protooncogenic protein c-Cbl binds to tubulin and stabilizes microtubules |
Q41758116 | The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk. |
Q28213787 | c-Cbl facilitates fibronectin matrix production by v-Abl-transformed NIH3T3 cells via activation of small GTPases |
Q28178593 | c-Cbl is a critical modulator of the Ron tyrosine kinase receptor |
Q54655562 | c-Cbl regulates glioma invasion through matrix metalloproteinase 2. |
Q40415906 | c-Cbl regulates migration of v-Abl-transformed NIH 3T3 fibroblasts via Rac1. |
Q42831849 | c-Cbl-facilitated cytoskeletal effects in v-Abl-transformed fibroblasts are regulated by membrane association of c-Cbl |