scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1004860569 |
P356 | DOI | 10.1038/SJ.ONC.1203750 |
P698 | PubMed publication ID | 10962563 |
P5875 | ResearchGate publication ID | 12358592 |
P2093 | author name string | K Vuori | |
E Larsen | |||
M Garcia-Guzman | |||
P2860 | cites work | cbl-3: a new mammalian cbl family protein | Q22009959 |
Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G | Q24309656 | ||
CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration | Q24311510 | ||
Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases | Q24316242 | ||
A Grb2-associated docking protein in EGF- and insulin-receptor signalling | Q24321653 | ||
CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells | Q24610534 | ||
Two species of human CRK cDNA encode proteins with distinct biological activities | Q24629936 | ||
Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor | Q24648537 | ||
Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation | Q41711750 | ||
The Cbl protooncogene product: from an enigmatic oncogene to center stage of signal transduction. | Q41756552 | ||
The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation | Q42676655 | ||
Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling | Q42802564 | ||
Mechanism of met oncogene activation | Q42811433 | ||
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor. | Q42824006 | ||
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas | Q45345804 | ||
Molecular cloning of a new transforming gene from a chemically transformed human cell line. | Q45345810 | ||
Regulation of β1-integrin-mediated cell adhesion by the CbI adaptor protein | Q47849795 | ||
Molecules in focus: The c-Cbl oncoprotein | Q56531398 | ||
Duplication and overexpression of the mutant allele of the MET proto-oncogene in multiple hereditary papillary renal cell tumours | Q77138821 | ||
Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas | Q77220529 | ||
The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor | Q78069495 | ||
SH2 domains recognize specific phosphopeptide sequences | Q27860748 | ||
cbl-b inhibits epidermal growth factor receptor signaling | Q28139234 | ||
Physiological signals and oncogenesis mediated through Crk family adapter proteins | Q28139609 | ||
Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL | Q28141139 | ||
The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase | Q28145635 | ||
Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7 | Q28146026 | ||
Induction of epithelial tubules by growth factor HGF depends on the STAT pathway | Q28259695 | ||
Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility | Q28281829 | ||
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family | Q28285975 | ||
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis | Q28295920 | ||
The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells | Q28609032 | ||
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1 | Q29617290 | ||
c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor | Q29618661 | ||
The ubiquitin-proteasome pathway: on protein death and cell life | Q29619270 | ||
The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway | Q30175936 | ||
Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential. | Q30176316 | ||
Activation of the JNK pathway is essential for transformation by the Met oncogene | Q30176542 | ||
Emerging components of the Crk oncogene product: the first identified adaptor protein | Q30176868 | ||
Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins | Q30192897 | ||
The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase | Q30193184 | ||
Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells | Q30193317 | ||
Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells | Q30194957 | ||
Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase | Q34358610 | ||
Efficient Cellular Transformation by the Met Oncoprotein Requires a Functional Grb2 Binding Site and Correlates with Phosphorylation of the Grb2-associated Proteins, Cbl and Gab1 | Q34434226 | ||
Association of the Multisubstrate Docking Protein Gab1 with the Hepatocyte Growth Factor Receptor Requires a Functional Grb2 Binding Site Involving Tyrosine 1356 | Q34434985 | ||
Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation. | Q34449405 | ||
Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells. | Q34482678 | ||
The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha | Q36164471 | ||
Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway | Q36565319 | ||
Activating mutations for the Met tyrosine kinase receptor in human cancer | Q36595980 | ||
A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration | Q38334944 | ||
c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption. | Q38352423 | ||
Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase | Q39575287 | ||
Involvement of Shc and Cbl-PI 3-kinase in Lyn-dependent proliferative signaling pathways for G-CSF. | Q40904570 | ||
Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts | Q40944647 | ||
Tyrosine kinase activity of the EGF receptor is enhanced by the expression of oncogenic 70Z-Cbl | Q41073646 | ||
P433 | issue | 35 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 4058-4065 | |
P577 | publication date | 2000-08-01 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk. | |
P478 | volume | 19 |
Q40768473 | A differentiation switch for genetically modified hepatocytes |
Q24537413 | APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes |
Q33996323 | Antagonizing c-Cbl enhances EGFR-dependent corneal epithelial homeostasis |
Q74423084 | Association of a new c-Cbl related protein with the very first stages of apoptosis induction |
Q34405560 | Beyond the RING: CBL proteins as multivalent adapters |
Q40750172 | C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus |
Q34205572 | Cbl: many adaptations to regulate protein tyrosine kinases |
Q33273613 | Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function |
Q30165423 | Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions |
Q30167857 | Crk family adaptors-signalling complex formation and biological roles |
Q36086815 | Gab1 mediates hepatocyte growth factor-stimulated mitogenicity and morphogenesis in multipotent myeloid cells. |
Q37710951 | Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms |
Q34050931 | Heterozygous germline mutations in the CBL tumor-suppressor gene cause a Noonan syndrome-like phenotype. |
Q33314672 | Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction |
Q28210330 | Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein |
Q30931355 | Network-constrained forest for regularized classification of omics data. |
Q50985118 | Physiological Signaling and Structure of the HGF Receptor MET. |
Q28278555 | Prostate cancer and the met hepatocyte growth factor receptor |
Q38363901 | Repression of c-Cbl leads to enhanced G-CSF Jak-STAT signaling without increased cell proliferation |
Q46025873 | Shear stress and VEGF activate IKK via the Flk-1/Cbl/Akt signaling pathway |
Q24297076 | Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins |
Q30167736 | The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl |
Q28207199 | The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met |
Q33853516 | The envelope glycoprotein of friend spleen focus-forming virus covalently interacts with and constitutively activates a truncated form of the receptor tyrosine kinase Stk. |
Q42169339 | The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport |
Q38056547 | What’s in a loop? |
Q28178593 | c-Cbl is a critical modulator of the Ron tyrosine kinase receptor |
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