Self-renewal related signaling in myeloid leukemia stem cells

scientific article published on 29 July 2011

Self-renewal related signaling in myeloid leukemia stem cells is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S12185-011-0901-0
P932PMC publication ID3339405
P698PubMed publication ID21800073
P5875ResearchGate publication ID51531474

P2093author name stringScott A Armstrong
Florian H Heidel
Brenton G Mar
P2860cites workLDL-receptor-related proteins in Wnt signal transductionQ24290392
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptorsQ24290574
GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoterQ24294866
Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assemblyQ24312910
Tankyrase inhibition stabilizes axin and antagonizes Wnt signallingQ24316697
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemiaQ24597256
Regulation of myeloid leukaemia by the cell-fate determinant MusashiQ24634359
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cellQ27861001
LDL-receptor-related protein 6 is a receptor for Dickkopf proteinsQ28116567
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathwayQ28118992
A cell initiating human acute myeloid leukaemia after transplantation into SCID miceQ28131777
Hedgehog signaling in animal development: paradigms and principlesQ28208463
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regenerationQ28238880
Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group BQ28247684
Mutations affecting segment number and polarity in DrosophilaQ28273492
Lack of beta-catenin affects mouse development at gastrulationQ28274575
In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehogQ28275763
Tissue repair and stem cell renewal in carcinogenesisQ28294006
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3betaQ28505773
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse nodeQ28594387
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CMLQ29614278
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stressQ29615562
Notch signalingQ29618190
Convergence of Wnt, beta-catenin, and cadherin pathwaysQ29619504
Imaging hematopoietic precursor division in real timeQ30481466
Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trialsQ33767211
Hedgehog signaling is dispensable for adult hematopoietic stem cell functionQ34039421
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemiaQ34157874
Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.Q34346883
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2.Q34568144
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitorsQ34641731
Granulocyte-macrophage colony-stimulating factor after initial chemotherapy for elderly patients with primary acute myelogenous leukemia. Cancer and Leukemia Group B.Q34722375
Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesisQ34727652
Notch signaling in hematopoiesis and early lymphocyte developmentQ34941720
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.Q34978382
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivoQ36488720
Gli1 is a target of Sonic hedgehog that induces ventral neural tube developmentQ36870138
Mitoxantrone versus daunorubicin in induction-consolidation chemotherapy--the value of low-dose cytarabine for maintenance of remission, and an assessment of prognostic factors in acute myeloid leukemia in the elderly: final report. European OrganizQ36895799
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generationQ37106907
FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic systemQ37121014
Hematopoietic stem cell development is dependent on blood flow.Q37294702
Hedgehog beyond medulloblastoma and basal cell carcinomaQ37677865
Targeting Wnt signaling: can we safely eradicate cancer stem cells?Q37763415
Front-line and salvage therapies with tyrosine kinase inhibitors and other treatments in chronic myeloid leukemiaQ37827278
An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activityQ38342595
β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cellsQ39620290
TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemiaQ39744014
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.Q39782714
DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequencyQ39815141
Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemiaQ40001372
The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivoQ40124647
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.Q40219637
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.Q40252270
Trans-repression of beta-catenin activity by nuclear receptorsQ40634804
Translational repression determines a neuronal potential in Drosophila asymmetric cell divisionQ40808595
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.Q42723875
Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trialsQ42849516
Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trialQ42851077
Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cellsQ44239025
Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells.Q46129185
An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth.Q46248213
beta-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemiaQ46345796
Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activationQ46388996
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacityQ47634506
Foxo3a is essential for maintenance of the hematopoietic stem cell pool.Q51960990
Down-regulation of Notch-1 expression decreases PU.1-mediated myeloid differentiation signaling in acute myeloid leukemia.Q52587062
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.Q53362332
Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years.Q54581100
Immobilization of Notch ligand, Delta-1, is required for induction of notch signalingQ73167897
Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesisQ81250982
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenanceQ81308407
Acute myeloid leukemia and the Wnt pathwayQ84423759
P433issue2
P921main subjectleukemiaQ29496
myeloid leukemiaQ11688946
P304page(s)109-117
P577publication date2011-07-29
P1433published inInternational Journal of HematologyQ6051416
P1476titleSelf-renewal related signaling in myeloid leukemia stem cells
P478volume94

Reverse relations

cites work (P2860)
Q38848436ADCY7 supports development of acute myeloid leukemia.
Q34047994Aberrant RNA splicing and mutations in spliceosome complex in acute myeloid leukemia
Q35677279Antagonism between granulocytic maturation and deacetylase inhibitor-induced apoptosis in acute promyelocytic leukaemia cells
Q37026763Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment
Q38749763Effect of Over-Expression of Zinc-Finger Protein (ZFX) on Self-Renewal and Drug-Resistance of Hepatocellular Carcinoma.
Q38051191Epigenetic regulation of hematopoiesis
Q92284294Expression and functional relevance of long non-coding RNAs in acute myeloid leukemia stem cells
Q37734751IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
Q92623047Mutations associated with a 17-gene leukemia stem cell score and the score's prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia
Q36699009Next-generation medicine: combining BCR-ABL and Hedgehog-targeted therapies
Q39019365Overexpression of ZFX confers self-renewal and chemoresistance properties in hepatocellular carcinoma
Q48939103Pituitary Regeneration: It'll Knock Your SOX Off!
Q47747424SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis
Q38106623Sensitivity and resistance of JAK2 inhibitors to myeloproliferative neoplasms
Q37707485Sex hormone drives blood stem cell reproduction.
Q92971685Signaling pathways involved in chronic myeloid leukemia pathogenesis: The importance of targeting Musashi2-Numb signaling to eradicate leukemia stem cells
Q36248867Targeting leukemia stem cells in vivo with antagomiR-126 nanoparticles in acute myeloid leukemia
Q35561510The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development
Q38998213The Interaction Between Niche and Hematopoietic Stem Cells
Q38254181The cancer stem cell hypothesis: a guide to potential molecular targets
Q36547690The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML.
Q38632898The role of the Wnt signaling pathway in cancer stem cells: prospects for drug development
Q26997109Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development

Search more.