PKM2 promotes stemness of breast cancer cell by through Wnt/β-catenin pathway

scientific article published on 22 October 2015

PKM2 promotes stemness of breast cancer cell by through Wnt/β-catenin pathway is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1053365064
P356DOI10.1007/S13277-015-4121-8
P698PubMed publication ID26493994

P2093author name stringZhigang Liu
Haifeng Sun
Zheng Zhao
Chengxue Dang
Wenjuan Chen
Zijun Liao
Zhangjun Song
Baoxia Lei
P2860cites workActivation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.Q50926584
Chronic versus acute myelogenous leukemia: a question of self-renewal.Q52062147
Stromal niche cells protect early leukemic FLT3-ITD+ progenitor cells against first-generation FLT3 tyrosine kinase inhibitors.Q54592057
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An adult tissue-specific stem cell molecular phenotype is activated in epithelial cancer stem cells and correlated to patient outcomeQ82296672
The prognostic value of lymph node ratio in node-positive breast cancer: a Dutch nationwide population-based studyQ86499705
A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cellsQ24310281
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Human pyruvate kinase M2: a multifunctional proteinQ24625882
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Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional networkQ28513471
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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating featuresQ29620020
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L- and M2-pyruvate kinase expression in renal cell carcinomas and their metastasesQ34341011
Three clonal types of keratinocyte with different capacities for multiplicationQ34393745
Telomerase and cancer stem cellsQ34569385
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Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progressionQ35679187
Self-renewal and solid tumor stem cellsQ35892127
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Transforming growth factor-beta signaling during epithelial-mesenchymal transformation: implications for embryogenesis and tumor metastasisQ36154999
Targeting Wnt signaling: can we safely eradicate cancer stem cells?Q37763415
Notch Signaling in the Regulation of Stem Cell Self-Renewal and DifferentiationQ37785203
The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivatorsQ37797633
Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogrammingQ37878387
Targeting cancer stem cells with an 131I-labeled anti-AC133 monoclonal antibody in human colorectal cancer xenograftsQ38910999
P433issue3
P304page(s)4223-4234
P577publication date2015-10-22
P1433published inTumor BiologyQ15757842
P1476titlePKM2 promotes stemness of breast cancer cell by through Wnt/β-catenin pathway
P478volume37

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cites work (P2860)
Q39443694Breast cancer stem cells as last soldiers eluding therapeutic burn: A hard nut to crack
Q89598674Leptin, Adiponectin, and Sam68 in Bone Metastasis from Breast Cancer
Q49959198Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN.
Q92761067Non-proteolytic ubiquitination of Hexokinase 2 by HectH9 controls tumor metabolism and cancer stem cell expansion
Q39374497Overexpression of pyruvate kinase M2 predicts a poor prognosis for patients with osteosarcoma
Q46489215Plasma TuM2-PK correlates with tumor size, CRP and CA 15-3 in metastatic breast carcinomas; short versus long term follow up study of the Egyptian breast cancer patients.
Q47094780Prognostic significance of metabolic enzyme pyruvate kinase M2 in breast cancer: A meta-analysis
Q42339119Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancer
Q58607131Signaling Pathways Induced by Leptin during Epithelial⁻Mesenchymal Transition in Breast Cancer
Q89667670Targeting cancer stem cell pathways for cancer therapy

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