WNT protein-independent constitutive nuclear localization of beta-catenin protein and its low degradation rate in thalamic neurons

scientific article published on 09 July 2011

WNT protein-independent constitutive nuclear localization of beta-catenin protein and its low degradation rate in thalamic neurons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.229666
P932PMC publication ID3173118
P698PubMed publication ID21757747

P50authorJacek KuźnickiQ16560755
Katarzyna MisztalQ59100202
Andrzej NagalskiQ59100205
Marta B WisniewskaQ63386798
P2093author name stringMateusz Ambrozkiewicz
P2860cites workNovel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/ArrowQ24291392
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The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cellsQ47605940
Nuclear localization of beta-catenin in adult mouse thalamus correlates with low levels of GSK-3betaQ48097834
Wnt signaling is required at distinct stages of development for the induction of the posterior forebrainQ48182309
GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleenQ48299832
Assessment of CMV, RSV and SYN1 promoters and the woodchuck post-transcriptional regulatory element in adenovirus vectors for transgene expression in cortical neuronal culturesQ48485317
Axotomy-induced neuronal death and reactive astrogliosis in the lateral geniculate nucleus following a lesion of the visual cortex in the rat.Q48505155
The derivatives of the Wnt3a lineage in the central nervous systemQ80802362
Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor poolQ81390907
Wnt signaling regulates symmetry of division of neural stem cells in the adult brain and in response to injuryQ83677362
Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6Q28115808
Wnt2 regulates progenitor proliferation in the developing ventral midbrainQ28116566
Balancing cell adhesion and Wnt signaling, the key role of beta-cateninQ28288763
LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brainQ28509315
Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutantsQ28509865
Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1Q28512684
Neuronal production and precursor proliferation defects in the neocortex of mice with loss of function in the canonical Wnt signaling pathwayQ28586950
Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalonQ28592524
Wnt signalling regulates adult hippocampal neurogenesisQ29619688
Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumorsQ29619814
GSK3: a multifaceted kinase in Wnt signalingQ33712410
Expression of the diabetes-associated gene TCF7L2 in adult mouse brainQ34252656
Bursting of thalamic neurons and states of vigilanceQ34504333
NMDA-receptor activation induces calpain-mediated beta-catenin cleavages for triggering gene expression.Q34608600
T-cell factors: turn-ons and turn-offsQ34634821
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.Q35122385
Adenomatous Polyposis Coli Is Essential for Both Neuronal Differentiation and Maintenance of Adult Neural Stem Cells in Subventricular Zone and HippocampusQ35915127
Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processingQ36375819
Wnt/beta-catenin signaling: new (and old) players and new insightsQ37109729
Wnt signaling from development to disease: insights from model systemsQ37342306
Synaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-beta-catenin at excitatory synapsesQ37431274
Endogenous Wnt signaling maintains neural progenitor cell potencyQ37436994
GSK-3 is a master regulator of neural progenitor homeostasisQ37670059
Targeting Wnt signaling: can we safely eradicate cancer stem cells?Q37763415
GSK3 signalling in neural developmentQ37774552
Members of the Wnt, Fz, and Frp gene families expressed in postnatal mouse cerebral cortexQ38341919
The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest inductionQ38350690
Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.Q38520593
Differential activity of Wnt/beta-catenin signaling in the embryonic mouse thalamus.Q39238298
Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patientsQ39766205
A protocol for rapid generation of recombinant adenoviruses using the AdEasy systemQ40124490
Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signalingQ40690911
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerizationQ41791636
Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortexQ42468444
Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channelsQ43702724
Regulation of cell survival in the developing thalamus: an in vitro analysisQ44413760
Expression of regulatory genes during differentiation of thalamic nuclei in mouse and monkeyQ44998263
Activity-dependent synaptic Wnt release regulates hippocampal long term potentiationQ46254513
Establishment of the telencephalon during gastrulation by local antagonism of Wnt signalingQ47073120
P4510describes a project that usesImageQuantQ112270642
P433issue36
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)31781-31788
P577publication date2011-07-09
P1433published inJournal of Biological ChemistryQ867727
P1476titleWNT protein-independent constitutive nuclear localization of beta-catenin protein and its low degradation rate in thalamic neurons
P478volume286

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cites work (P2860)
Q64866631Genomic convergence of locus-based GWAS meta-analysis identifies AXIN1 as a novel Parkinson's gene
Q92541896Inflammatory breast cancer: Activation of the aryl hydrocarbon receptor and its target CYP1B1 correlates closely with Wnt5a/b-β-catenin signalling, the stem cell phenotype and disease progression
Q34479682Novel β-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability
Q38078834Physiological role of β-catenin/TCF signaling in neurons of the adult brain
Q37301034Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain
Q34169022The expression and activity of β-catenin in the thalamus and its projections to the cerebral cortex in the mouse embryo.
Q92892451Wnt/β-catenin signaling in brain development and mental disorders: keeping TCF7L2 in mind

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