review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Maocai Yan | Q56380847 |
P2093 | author name string | Jing An | |
Guanqun Li | |||
P2860 | cites work | Structure of a human Tcf4-beta-catenin complex | Q24291910 |
Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation | Q24301873 | ||
Identification of c-MYC as a target of the APC pathway | Q24310637 | ||
Wnt/beta-catenin signaling: components, mechanisms, and diseases | Q24630938 | ||
Terminal regions of beta-catenin come into view | Q24642163 | ||
Wnt Signaling in Cancer Stem Cell Biology | Q26746101 | ||
Crystal structure of a beta-catenin/Tcf complex | Q27629129 | ||
The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin | Q27631714 | ||
Crystal Structure of a Full-Length β-Catenin | Q27650057 | ||
Three-dimensional structure of the armadillo repeat region of beta-catenin | Q27743283 | ||
The Wnt signaling pathway in development and disease | Q27861019 | ||
The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis | Q28144201 | ||
dishevelled and armadillo act in the wingless signalling pathway in Drosophila | Q28237239 | ||
A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin | Q28252615 | ||
From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion | Q28256172 | ||
Crystal structure of a beta-catenin/BCL9/Tcf4 complex | Q28269490 | ||
The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation | Q28294000 | ||
Structure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction | Q83188973 | ||
WNT signalling pathways as therapeutic targets in cancer | Q29615666 | ||
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex | Q31038919 | ||
2,4-Diamino-quinazolines as inhibitors of beta-catenin/Tcf-4 pathway: Potential treatment for colorectal cancer | Q33488429 | ||
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway | Q33843109 | ||
An updated overview on Wnt signaling pathways: a prelude for more | Q34122601 | ||
Virtual screening methods as tools for drug lead discovery from large chemical libraries | Q34422811 | ||
Rational design of small-molecule inhibitors for β-catenin/T-cell factor protein-protein interactions by bioisostere replacement | Q34526416 | ||
A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells | Q34787867 | ||
Beta-catenin simultaneously induces activation of the p53-p21WAF1 pathway and overexpression of cyclin D1 during squamous differentiation of endometrial carcinoma cells | Q35098096 | ||
Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells | Q35557572 | ||
β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. | Q35585837 | ||
Can we safely target the WNT pathway? | Q35591995 | ||
Discovery of Selective Small-Molecule Inhibitors for the β-Catenin/T-Cell Factor Protein-Protein Interaction through the Optimization of the Acyl Hydrazone Moiety. | Q35634252 | ||
Enhancement of Radiation Sensitivity in Lung Cancer Cells by a Novel Small Molecule Inhibitor That Targets the β-Catenin/Tcf4 Interaction | Q35970241 | ||
Wnt/beta-catenin signaling pathway as a novel cancer drug target | Q35971885 | ||
Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin. | Q36410444 | ||
Transcription under the control of nuclear Arm/beta-catenin. | Q36483987 | ||
Mining the Wnt pathway for cancer therapeutics | Q36670448 | ||
CWP232228 targets liver cancer stem cells through Wnt/β-catenin signaling: a novel therapeutic approach for liver cancer treatment | Q37190326 | ||
Targeting Wnt signaling: can we safely eradicate cancer stem cells? | Q37763415 | ||
Wnt signaling in stem and cancer stem cells | Q38076537 | ||
Virtual screening in drug design | Q38097356 | ||
Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control | Q38256327 | ||
Henryin, an ent-kaurane diterpenoid, inhibits Wnt signaling through interference with β-catenin/TCF4 interaction in colorectal cancer cells | Q38314212 | ||
A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis. | Q38813747 | ||
A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/β-catenin signaling and colon cancer cell tumorigenesis | Q38857207 | ||
Design, synthesis, and biological evaluation of new diaminoquinazolines as β-catenin/Tcf4 pathway inhibitors | Q39415146 | ||
Inhibition of beta-catenin/Tcf signaling by flavonoids. | Q39690460 | ||
Design and synthesis of novel diaminoquinazolines with in vivo efficacy for beta-catenin/T-cell transcriptional factor 4 pathway inhibition | Q39760826 | ||
High-Throughput Selectivity Assays for Small-Molecule Inhibitors of β-Catenin/T-Cell Factor Protein-Protein Interactions | Q39777606 | ||
The Bcl-w promoter is activated by beta-catenin/TCF4 in human colorectal carcinoma cells | Q39898570 | ||
Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells. | Q40465905 | ||
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. | Q40543122 | ||
Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis | Q40855199 | ||
Hot spots in Tcf4 for the interaction with beta-catenin | Q44376501 | ||
Targeting the Tcf4 G13ANDE17 binding site to selectively disrupt β-catenin/T-cell factor protein-protein interactions. | Q51773966 | ||
Transcriptional activation of interleukin-8 by beta-catenin-Tcf4. | Q52115561 | ||
Inhibition of protein-protein interactions: The discovery of druglike β-catenin inhibitors by combining virtual and biophysical screening | Q57937295 | ||
P433 | issue | 11 | |
P304 | page(s) | 1185-1197 | |
P577 | publication date | 2017-01-01 | |
P1433 | published in | Experimental Biology and Medicine | Q15716535 |
P1476 | title | Discovery of small molecule inhibitors of the Wnt/β-catenin signaling pathway by targeting β-catenin/Tcf4 interactions | |
P478 | volume | 242 |
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Q92236596 | TMF inhibits miR-29a/Wnt/β-catenin signaling through upregulating Foxo3a activity in osteoarthritis chondrocytes |
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