| scholarly article | Q13442814 |
| P356 | DOI | 10.1517/14728222.2016.1154945 |
| P8608 | Fatcat ID | release_m3mjricr4bfu7mknxzvlhlzu6q |
| P698 | PubMed publication ID | 26882052 |
| P2093 | author name string | Jing Li | |
| Juan Chen | |||
| Xiaoming Liu | |||
| William C Cho | |||
| Juan Shi | |||
| Jiali Yang | |||
| Jinxi He | |||
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| Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-small-cell lung cancer | Q28260824 | ||
| Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation | Q28306934 | ||
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| Inhibitory Effects of Salinomycin on Cell Survival, Colony Growth, Migration, and Invasion of Human Non-Small Cell Lung Cancer A549 and LNM35: Involvement of NAG-1 | Q28534136 | ||
| Mechanism of Resistance and Novel Targets Mediating Resistance to EGFR and c-Met Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer | Q28547446 | ||
| Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers | Q29615475 | ||
| WNT signalling pathways as therapeutic targets in cancer | Q29615666 | ||
| Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma | Q30318752 | ||
| Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis | Q38521125 | ||
| Clinicopathological significance of ALDH1A1 in lung, colorectal, and breast cancers: a meta-analysis | Q38558296 | ||
| MiR-761 Promotes Progression and Metastasis of Non-Small Cell Lung Cancer by Targeting ING4 and TIMP2. | Q38843313 | ||
| Silencing of LRRFIP1 reverses the epithelial-mesenchymal transition via inhibition of the Wnt/β-catenin signaling pathway. | Q38866999 | ||
| Wnt signaling regulates the stemness of lung cancer stem cells and its inhibitors exert anticancer effect on lung cancer SPC-A1 cells | Q38904614 | ||
| Inhibition of β-Catenin enhances the anticancer effect of irreversible EGFR-TKI in EGFR-mutated non-small-cell lung cancer with a T790M mutation. | Q38941502 | ||
| Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status | Q38942314 | ||
| MicroRNA-191, by promoting the EMT and increasing CSC-like properties, is involved in neoplastic and metastatic properties of transformed human bronchial epithelial cells | Q38953681 | ||
| Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both β-catenin dependent and independent Wnt signalling. | Q38957643 | ||
| Anti-tumor activity of three ginsenoside derivatives in lung cancer is associated with Wnt/β-catenin signaling inhibition | Q38958638 | ||
| Dishevelled-3 activates p65 to upregulate p120-catenin transcription via a p38-dependent pathway in non-small cell lung cancer | Q38962862 | ||
| Curcumin suppresses proliferation and invasion in non-small cell lung cancer by modulation of MTA1-mediated Wnt/β-catenin pathway | Q38983853 | ||
| Targeting Wnts at the source--new mechanisms, new biomarkers, new drugs | Q38434892 | ||
| Translational potential of cancer stem cells: A review of the detection of cancer stem cells and their roles in cancer recurrence and cancer treatment | Q38476083 | ||
| Interplay between microRNAs and WNT/β-catenin signalling pathway regulates epithelial-mesenchymal transition in cancer | Q38508400 | ||
| miR-483-5p promotes invasion and metastasis of lung adenocarcinoma by targeting RhoGDI1 and ALCAM. | Q39006783 | ||
| Activated leukocyte cell adhesion molecule (CD166): an "inert" cancer stem cell marker for non-small cell lung cancer? | Q39026693 | ||
| MicroRNAs associated with tumour migration, invasion and angiogenic properties in A549 and SK-Lu1 human lung adenocarcinoma cells. | Q39041381 | ||
| Silibinin inhibits β-catenin/ZEB1 signaling and suppresses bladder cancer metastasis via dual-blocking epithelial-mesenchymal transition and stemness | Q39099119 | ||
| hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression. | Q39124675 | ||
| β-Catenin overexpression is associated with gefitinib resistance in non-small cell lung cancer cells | Q39147460 | ||
| Inhibition of cytoplasmic GSK-3β increases cisplatin resistance through activation of Wnt/β-catenin signaling in A549/DDP cells | Q39152228 | ||
| β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma | Q39173908 | ||
| 2,3,6-Trisubstituted quinoxaline derivative, a small molecule inhibitor of the Wnt/beta-catenin signaling pathway, suppresses cell proliferation and enhances radiosensitivity in A549/Wnt2 cells | Q39205233 | ||
| β-Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/β-catenin-signaling pathway | Q39454255 | ||
| The hypomethylation agent bisdemethoxycurcumin acts on the WIF-1 promoter, inhibits the canonical Wnt pathway and induces apoptosis in human non-small-cell lung cancer | Q39471041 | ||
| The gamma catenin/CBP complex maintains survivin transcription in β-catenin deficient/depleted cancer cells | Q39620090 | ||
| Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells | Q39751974 | ||
| ING4 induces cell growth inhibition in human lung adenocarcinoma A549 cells by means of Wnt-1/beta-catenin signaling pathway | Q39993710 | ||
| Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. | Q40543122 | ||
| Constitutive activation of the Wnt signaling pathway by CTNNB1 (beta-catenin) mutations in a subset of human lung adenocarcinoma | Q40828450 | ||
| Characterization of microRNA transcriptome in tumor, adjacent, and normal tissues of lung squamous cell carcinoma. | Q41153497 | ||
| Stem cell-like ALDH(bright) cellular states in EGFR-mutant non-small cell lung cancer: a novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin | Q41878464 | ||
| EMX2 is epigenetically silenced and suppresses growth in human lung cancer | Q42729659 | ||
| Suppression of Wnt signaling by the miR-29 family is mediated by demethylation of WIF-1 in non-small-cell lung cancer | Q47794745 | ||
| Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer. | Q53326540 | ||
| Wnt signaling promoter hypermethylation distinguishes lung primary adenocarcinomas from colorectal metastasis to the lung. | Q53341755 | ||
| Mechanism of miR-21 via Wnt/β-catenin signaling pathway in human A549 lung cancer cells and Lewis lung carcinoma in mice. | Q53415969 | ||
| Wnt3 gene expression promotes tumor progression in non-small cell lung cancer. | Q54340040 | ||
| Aberrant Wnt1/β-catenin expression is an independent poor prognostic marker of non-small cell lung cancer after surgery. | Q54611531 | ||
| DNA Methylation and Cancer | Q57239860 | ||
| Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex | Q31038919 | ||
| A small-molecule inhibitor of Tcf/beta-catenin signaling down-regulates PPARgamma and PPARdelta activities | Q33324196 | ||
| A first-in-human phase I dose-escalation, pharmacokinetic, and pharmacodynamic evaluation of intravenous LY2090314, a glycogen synthase kinase 3 inhibitor, administered in combination with pemetrexed and carboplatin | Q33426189 | ||
| Molecular characterisation of side population cells with cancer stem cell-like characteristics in small-cell lung cancer. | Q33566627 | ||
| Genetic variants of the Wnt signaling pathway as predictors of recurrence and survival in early-stage non-small cell lung cancer patients | Q33705233 | ||
| Molecular docking studies of flavonoids for their inhibition pattern against β-catenin and pharmacophore model generation from experimentally known flavonoids to fabricate more potent inhibitors for Wnt signaling pathway | Q33833103 | ||
| Fibulin-3 suppresses Wnt/β-catenin signaling and lung cancer invasion. | Q34009946 | ||
| Aberrant nuclear localization and gene mutation of beta-catenin in low-grade adenocarcinoma of fetal lung type: up-regulation of the Wnt signaling pathway may be a common denominator for the development of tumors that form morules | Q34133482 | ||
| NGX6 inhibits cell invasion and adhesion through suppression of Wnt/beta-catenin signal pathway in colon cancer | Q34169467 | ||
| Interactions between cancer stem cells and their niche govern metastatic colonization | Q34239769 | ||
| Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors | Q34323825 | ||
| AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model | Q34350571 | ||
| β-catenin contributes to lung tumor development induced by EGFR mutations | Q34353437 | ||
| Cardio-miRNAs and onco-miRNAs: circulating miRNA-based diagnostics for non-cancerous and cancerous diseases | Q34391443 | ||
| Silencing of bidirectional promoters by DNA methylation in tumorigenesis | Q34527442 | ||
| Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature | Q34562736 | ||
| Distinct radiosensitivity of lung carcinoma stem-like side population and main population cells | Q34628749 | ||
| Evidence for tankyrases as antineoplastic targets in lung cancer. | Q34690600 | ||
| A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells | Q34787867 | ||
| Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer. | Q34788226 | ||
| Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma | Q34976628 | ||
| Clinical significance of aberrant Wnt7a promoter methylation in human non-small cell lung cancer in Koreans | Q35028440 | ||
| Molecularly targeted therapies in non-small-cell lung cancer annual update 2014 | Q35136424 | ||
| Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells | Q35147451 | ||
| Astrocyte elevated gene-1(AEG-1) induces epithelial-mesenchymal transition in lung cancer through activating Wnt/β-catenin signaling | Q35174883 | ||
| Stimulation of Wnt/β-catenin signaling pathway with Wnt agonist reduces organ injury after hemorrhagic shock. | Q35220618 | ||
| Activation of Wnt/β-catenin signalling promotes mesenchymal stem cells to repair injured alveolar epithelium induced by lipopolysaccharide in mice | Q35552670 | ||
| Can we safely target the WNT pathway? | Q35591995 | ||
| miR-203 Inhibits Frizzled-2 Expression via CD82/KAI1 Expression in Human Lung Carcinoma Cells | Q35679905 | ||
| The ameliorative effect of silibinin against radiation-induced lung injury: protection of normal tissue without decreasing therapeutic efficacy in lung cancer | Q35682826 | ||
| Targeting DDX3 with a small molecule inhibitor for lung cancer therapy | Q35822589 | ||
| Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung. | Q35853581 | ||
| Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update | Q35904534 | ||
| Elevated β-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs | Q35948915 | ||
| A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction | Q36056178 | ||
| Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators | Q36067911 | ||
| Silibinin inhibits Wnt/β-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells | Q36303639 | ||
| Inhibition of lung cancer cells growth, motility and induction of apoptosis by Klotho, a novel secreted Wnt antagonist, in a dose-dependent manner | Q36312166 | ||
| Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription | Q36370019 | ||
| Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice | Q36383418 | ||
| DNA Methylation status of Wnt antagonist SFRP5 can predict the response to the EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer. | Q36471888 | ||
| Wnt pathway activation predicts increased risk of tumor recurrence in patients with stage I nonsmall cell lung cancer | Q36536565 | ||
| Mutations of the beta- and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas | Q36623104 | ||
| Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis | Q36638089 | ||
| Role of Wnt Inhibitory Factor-1 in Inhibition of Bisdemethoxycurcumin Mediated Epithelial-to-Mesenchymal Transition in Highly Metastatic Lung Cancer 95D Cells | Q36794497 | ||
| Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition | Q36905632 | ||
| Anti-HDGF targets cancer and cancer stromal stem cells resistant to chemotherapy | Q36998991 | ||
| Lung cancer stem cells | Q37182291 | ||
| Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. | Q37395251 | ||
| The role of microRNAs in the regulation of cancer stem cells | Q37428403 | ||
| Wif1 hypermethylation as unfavorable prognosis of non-small cell lung cancers with EGFR mutation | Q37462417 | ||
| Flow cytometric analysis of CD133- and EpCAM-positive cells in the peripheral blood of patients with lung cancer | Q37503324 | ||
| Wnt signalling and cancer stem cells. | Q37539422 | ||
| Cancer stem cells in lung cancer: Evidence and controversies. | Q37709551 | ||
| Targeting Wnt signaling: can we safely eradicate cancer stem cells? | Q37763415 | ||
| A systematic-analysis of predicted miR-21 targets identifies a signature for lung cancer | Q37975821 | ||
| Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer: a new era begins. | Q38119594 | ||
| Exploiting APC function as a novel cancer therapy | Q38160580 | ||
| Cancer stem cells: A contentious hypothesis now moving forward. | Q38170914 | ||
| Safely targeting cancer stem cells via selective catenin coactivator antagonism | Q38224211 | ||
| Klotho: a novel biomarker for cancer | Q38236358 | ||
| The emerging role of microRNAs in resistance to lung cancer treatments. | Q38319706 | ||
| MicroRNAs and Targeted Therapies in Non-small Cell Lung Cancer: Minireview | Q38328822 | ||
| Ror2 as a therapeutic target in cancer | Q38329559 | ||
| Insight into the role of Wnt5a-induced signaling in normal and cancer cells | Q38331676 | ||
| Development of Small Molecules Targeting the Wnt Signaling Pathway in Cancer Stem Cells for the Treatment of Colorectal Cancer | Q38387547 | ||
| Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy | Q38402026 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | lung cancer | Q47912 |
| P304 | page(s) | 999-1015 | |
| P577 | publication date | 2016-02-16 | |
| P1433 | published in | Expert Opinion on Therapeutic Targets | Q5421214 |
| P1476 | title | Wnt signaling as potential therapeutic target in lung cancer | |
| P478 | volume | 20 |
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