Conserved region 3 of human papillomavirus 16 E7 contributes to deregulation of the retinoblastoma tumor suppressor

scientific article

Conserved region 3 of human papillomavirus 16 E7 contributes to deregulation of the retinoblastoma tumor suppressor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01637-12
P932PMC publication ID3503127
P698PubMed publication ID23015707

P2093author name stringLawrence Banks
Paola Massimi
Gary S Shaw
Joe S Mymryk
Katherine Hung
Frederick A Dick
Biljana Todorovic
Nikita Avvakumov
P2860cites workHuman papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressorQ36098917
A point mutational analysis of human papillomavirus type 16 E7 proteinQ36828310
The major human papillomavirus protein in cervical cancers is a cytoplasmic phosphoproteinQ36888103
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene productQ37016112
Rapid induction of senescence in human cervical carcinoma cellsQ37268828
pRb, a local chromatin organizer with global possibilitiesQ37588543
Long term protection against cervical infection with the human papillomavirus: review of currently available vaccinesQ37838646
Identification of a novel retinoblastoma gene product binding site on human papillomavirus type 16 E7 proteinQ38310322
Induction of pRb degradation by the human papillomavirus type 16 E7 protein is essential to efficiently overcome p16INK4a-imposed G1 cell cycle ArrestQ39602729
Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.Q39606496
The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificityQ39633445
HPV E6 degradation of p53 and PDZ containing substrates in an E6AP null backgroundQ40068344
The adenovirus E4orf6 E3 ubiquitin ligase complex assembles in a novel fashionQ40157700
pRB Contains an E2F1-Specific Binding Domain that Allows E2F1-Induced Apoptosis to Be Regulated Separately from Other E2F ActivitiesQ40629059
Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosisQ41071971
E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.Q41158814
Transcription of human papillomavirus type-18 DNA in human cervical carcinoma cell linesQ44914495
Solution structure of the partially folded high-risk human papilloma virus 45 oncoprotein E7.Q45417338
Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomasQ70175894
An integral membrane green fluorescent protein marker, Us9-GFP, is quantitatively retained in cells during propidium iodide-based cell cycle analysis by flow cytometryQ74644944
The biochemical basis of CDK phosphorylation-independent regulation of E2F1 by the retinoblastoma proteinQ82810796
Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteinsQ22253968
Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressorQ24292803
Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein. Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7Q24296551
The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylationQ24300757
Interaction of the HPV E7 proteins with the pCAF acetyltransferaseQ24305508
Cyclin-binding motifs are essential for the function of p21CIP1Q24316125
Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedureQ28131658
Retinoblastoma protein recruits histone deacetylase to repress transcriptionQ28262144
The regulation of E2F by pRB-family proteinsQ28278789
FDA licensure of bivalent human papillomavirus vaccine (HPV2, Cervarix) for use in females and updated HPV vaccination recommendations from the Advisory Committee on Immunization Practices (ACIP)Q28283721
Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesionsQ28301685
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene productQ29618372
E2F: a link between the Rb tumor suppressor protein and viral oncoproteinsQ29618375
Classification of papillomavirusesQ29618731
Evidence for a causal association between human papillomavirus and a subset of head and neck cancersQ33180284
The human papillomavirus E7 oncoprotein functionally interacts with the S4 subunit of the 26 S proteasomeQ33292204
The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growthQ33292242
Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytesQ33844017
Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines.Q33929053
Structure-function analysis of the human papillomavirus type 16 E7 oncoproteinQ33932831
The Pezcoller lecture: cancer cell cycles revisitedQ33987290
Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.Q34122679
The retinoblastoma tumour suppressor in development and cancerQ34161991
Retinoblastoma protein partnersQ34305195
Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoproteinQ34742793
Human papillomavirus E7 enhances hypoxia-inducible factor 1-mediated transcription by inhibiting binding of histone deacetylasesQ34799489
The E7 open reading frame acts in cis and in trans to mediate differentiation-dependent activities in the human papillomavirus type 16 life cycle.Q35192986
Systematic analysis of the amino acid residues of human papillomavirus type 16 E7 conserved region 3 involved in dimerization and transformationQ35382611
Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathwaysQ35815917
Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cellsQ35838905
Human papillomavirus vaccines launch a new era in cervical cancer preventionQ35944623
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectretinoblastomaQ500695
human papillomavirus 16Q69461345
P304page(s)13313-13323
P577publication date2012-09-26
P1433published inJournal of VirologyQ1251128
P1476titleConserved region 3 of human papillomavirus 16 E7 contributes to deregulation of the retinoblastoma tumor suppressor
P478volume86

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cites work (P2860)
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Q38789833ERK Signaling Pathway Is Involved in HPV-16 E6 but not E7 Oncoprotein-Induced HIF-1α Protein Accumulation in NSCLC Cells
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