A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication

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A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01593-07
P932PMC publication ID2224595
P698PubMed publication ID17989180
P5875ResearchGate publication ID5857904

P2093author name stringYoshitaka Sato
Ayumi Kudoh
Hiroki Isomura
Sanae Nakayama
Satoko Iwahori
Takayuki Murata
Tatsuya Tsurumi
Mark F Stinski
P2860cites workInactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene expressionQ24543400
Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86Q24670535
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
Functional profiling of a human cytomegalovirus genomeQ28185252
Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase IIQ28199201
The general transcription factors of RNA polymerase IIQ28298663
Integrating mRNA processing with transcriptionQ28610124
TBP, a universal eukaryotic transcription factor?Q28626484
An extensive network of coupling among gene expression machinesQ29547273
Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutantQ33782001
A cis repression sequence adjacent to the transcription start site of the human cytomegalovirus US3 gene is required to down regulate gene expression at early and late times after infectionQ33785972
Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replicationQ33908697
High efficiency mutagenesis, repair, and engineering of chromosomal DNA using single-stranded oligonucleotidesQ33948878
Requirement of multiple cis-acting elements in the human cytomegalovirus major immediate-early distal enhancer for viral gene expression and replicationQ34326898
Human cytomegalovirus gene expression during infection of primary hematopoietic progenitor cells: a model for latencyQ34415946
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
The human cytomegalovirus major immediate-early enhancer determines the efficiency of immediate-early gene transcription and viral replication in permissive cells at low multiplicity of infectionQ34743775
Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expressionQ34998851
The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus.Q35784878
Growth kinetics of human cytomegalovirus are altered in monocyte-derived macrophages.Q35839951
The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesisQ35857242
The human cytomegalovirus virion possesses an activated casein kinase II that allows for the rapid phosphorylation of the inhibitor of NF-kappaB, IkappaBalphaQ35857513
Cellular or viral protein binding to a cytomegalovirus promoter transcription initiation site: effects on transcriptionQ35861289
Effect of a modulator deletion on transcription of the human cytomegalovirus major immediate-early genes in infected undifferentiated and differentiated cells.Q35876849
The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infectionQ35887796
Human cytomegalovirus latent infection of granulocyte-macrophage progenitorsQ35945151
Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start siteQ36680389
A cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2Q36680417
A human cytomegalovirus early gene has three inducible promoters that are regulated differentially at various times after infectionQ36780228
The IE2 gene products of human cytomegalovirus specifically down-regulate expression from the major immediate-early promoter through a target sequence located near the cap siteQ36796246
Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducible promoterQ36919288
Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individualsQ37313098
Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replicationQ37596556
Sequence of protein synthesis in cells infected by human cytomegalovirus: early and late virus-induced polypeptidesQ37601559
Binding of the human cytomegalovirus 80-kDa immediate-early protein (IE2) to minor groove A/T-rich sequences bounded by CG dinucleotides is regulated by protein oligomerization and phosphorylationQ38329864
Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genesQ39602194
Regulation of a human cytomegalovirus immediate-early gene (US3) by a silencer-enhancer combinationQ39872965
A novel mechanism for persistence of human cytomegalovirus in macrophagesQ39873810
Unrestricted replication of human cytomegalovirus in hydrocortisone-treated macrophagesQ40113755
Human cytomegalovirus gene expression is silenced by Daxx-mediated intrinsic immune defense in model latent infections established in vitroQ40114561
Human cytomegalovirus productively infects primary differentiated macrophagesQ40115481
A sequence motif in the simian virus 40 (SV40) early core promoter affects alternative splicing of transcribed mRNA.Q40164682
Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoterQ40221207
Analysis of proteins binding to the proximal promoter region of the human cytomegalovirus IE-1/2 enhancer/promoter reveals both consensus and aberrant recognition sequences for transcription factors Sp1 and CREB.Q40422902
Cloning of the genomes of human cytomegalovirus strains Toledo, TownevarRIT3, and Towne long as BACs and site-directed mutagenesis using a PCR-based techniqueQ40659928
Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression.Q40677826
Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cellsQ42154128
Organization and expression of the major genes from the long inverted repeat of the human cytomegalovirus genomeQ70152485
Tissue macrophages are infected by human cytomegalovirus in vivoQ70826656
Fibroblasts, epithelial cells, endothelial cells and smooth muscle cells are major targets of human cytomegalovirus infection in lung and gastrointestinal tissuesQ73107960
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectCytomegalovirusQ6946
P304page(s)849-858
P577publication date2007-11-07
P1433published inJournal of VirologyQ1251128
P1476titleA cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication
P478volume82

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