Cannabinoid-1 receptor: a novel target for the treatment of neuropsychiatric disorders

scientific article

Cannabinoid-1 receptor: a novel target for the treatment of neuropsychiatric disorders is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1517/14728222.10.2.203
P698PubMed publication ID16548770

P2093author name stringBasalingappa L Hungund
K Yaragudri Vinod
P2860cites workEndocannabinoid signalling in the blood of patients with schizophreniaQ24800061
CNR1, central cannabinoid receptor gene, associated with susceptibility to hebephrenic schizophreniaQ28206825
Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cellsQ28212245
Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonistQ28262546
Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophreniaQ44748286
Upregulation of CB1 receptors and agonist-stimulated [35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victimsQ44765964
Chronic ethanol consumption regulates cannabinoid CB1 receptor gene expression in selected regions of rat brainQ44785227
Differences in basal cannabinoid CB1 receptor function in selective brain areas and vulnerability to voluntary alcohol consumption in Fawn Hooded and Wistar rats.Q44945320
Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptomsQ45049153
Enhancement of anxiety-like responsiveness to the cannabinoid CB(1) receptor agonist HU-210 following chronic stressQ45069054
Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stressQ45138851
Enhancing cannabinoid neurotransmission augments the extinction of conditioned fearQ45215137
Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodentsQ45251047
Elevated levels of endocannabinoids and CB1 receptor-mediated G-protein signaling in the prefrontal cortex of alcoholic suicide victimsQ45287377
Ethanol self-administration and ethanol conditioned place preference are reduced in mice lacking cannabinoid CB1 receptorsQ46685295
In-vitro and in-vivo action of cannabinoidsQ48109698
Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat.Q48183236
Function of cannabinoid receptors in the neuroendocrine regulation of hormone secretionQ48285208
The functional neuroanatomy of brain cannabinoid receptorsQ48285221
Chronic ethanol increases the cannabinoid receptor agonist anandamide and its precursor N-arachidonoylphosphatidylethanolamine in SK-N-SH cellsQ48292854
Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory actionQ48309971
Anandamide hydrolysis by human cells in culture and brainQ48346766
Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptorsQ48664473
Genetic deletion of CB1 receptors improves non-associative learningQ48880717
Involvement of CB1 cannabinoid receptors in emotional behaviour.Q51055974
Anandamide: a candidate neurotransmitter heads for the big leagues.Q51090766
Acute administration of the CB1 cannabinoid receptor antagonist SR 141716A induces anxiety-like responses in the rat.Q51106735
The motivation for beer in rats: effects of ritanserin, naloxone and SR 141716.Q52897872
EndocannabinoidsQ55282369
Pharmacology of AntidepressantsQ56016664
Identification and functional characterization of brainstem cannabinoid CB2 receptorsQ28276972
2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brainQ28290395
Molecular characterization of a peripheral receptor for cannabinoidsQ28298338
Cognitive and emotional influences in anterior cingulate cortexQ29547440
Isolation and structure of a brain constituent that binds to the cannabinoid receptorQ29547476
Modulation of anxiety through blockade of anandamide hydrolysisQ29615902
Formation and inactivation of endogenous cannabinoid anandamide in central neuronsQ29620558
Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developmentsQ33695248
The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptorsQ33940288
Endogenous cannabinoids mediate retrograde signalling at hippocampal synapsesQ33940688
Cannabis as a risk factor for psychosis: systematic reviewQ33986870
Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptorsQ34098397
Endocannabinoid signaling in the brainQ34125520
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysisQ34234907
Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjectsQ34253509
Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potentialQ34418106
Cannabis use and psychotic disorders: an updateQ34555939
Neuronal localization of cannabinoid receptors in the basal ganglia of the rat.Q34602111
Schizophrenia: diverse approaches to a complex diseaseQ34614652
The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actionsQ35045001
Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranesQ35592076
The etiopathogenesis of schizophreniasQ35951559
Role of endogenous cannabinoids in cognition and emotionalityQ36198923
Pharmacology of cannabinoid receptorsQ40437020
Search for endogenous ligands of the cannabinoid receptorQ40643774
Dopamine activation of endogenous cannabinoid signaling in dorsal striatumQ41646203
Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brainQ42451047
Antidepressant-like and anorectic effects of the cannabinoid CB1 receptor inverse agonist AM251 in miceQ42615187
The effects of genetic and pharmacological blockade of the CB1 cannabinoid receptor on anxiety.Q42686860
The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolaseQ43512138
Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use.Q43581230
Cannabis induced dopamine release: an in-vivo SPECT studyQ43744306
Coexpression of the cannabinoid receptor type 1 with dopamine and serotonin receptors in distinct neuronal subpopulations of the adult mouse forebrain.Q43873792
Chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid CB(1) receptor binding and mRNA levelsQ43890403
Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour.Q43975380
The endogenous cannabinoid system controls extinction of aversive memoriesQ44085607
Cellular localization of cannabinoid receptors and activated G-proteins in rat anterior cingulate cortexQ44127906
Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbensQ44299680
Opioid and cannabinoid receptor-mediated regulation of the increase in adrenocorticotropin hormone and corticosterone plasma concentrations induced by central administration of delta(9)-tetrahydrocannabinol in ratsQ44352771
'One-trial sensitization' to the anxiolytic-like effects of cannabinoid receptor antagonist SR141716A in the mouse elevated plus-maze.Q44386848
Chronic ethanol inhibits the anandamide transport and increases extracellular anandamide levels in cerebellar granule neurons.Q44392539
Decreased alcohol self-administration and increased alcohol sensitivity and withdrawal in CB1 receptor knockout mice.Q44697078
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcannabinoid receptorQ421237
cannabinoidsQ422936
CNR2Q17907844
P304page(s)203-210
P577publication date2006-04-01
P1433published inExpert Opinion on Therapeutic TargetsQ5421214
P1476titleCannabinoid-1 receptor: a novel target for the treatment of neuropsychiatric disorders
P478volume10

Reverse relations

cites work (P2860)
Q40647052Altered CB1 receptor coupling to G-proteins in the post-mortem caudate nucleus and cerebellum of alcoholic subjects.
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Q34609936Expression of CB1 cannabinoid receptor in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression
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Q30465425Startle reactivity and prepulse inhibition in prodromal and early psychosis: effects of age, antipsychotics, tobacco and cannabis in a vulnerable population
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