| P50 | author | Melissa J. Moore | Q85954688 |
| P2093 | author name string | Aaron A Hoskins | |
| P2860 | cites work | Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity | Q24563898 |
| | U4 small nuclear RNA dissociates from a yeast spliceosome and does not participate in the subsequent splicing reaction | Q24594525 |
| | Early commitment of yeast pre-mRNA to the spliceosome pathway | Q24627964 |
| | Prp43p is a DEAH-box spliceosome disassembly factor essential for ribosome biogenesis | Q27936468 |
| | Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components | Q27937542 |
| | The tandem affinity purification (TAP) method: a general procedure of protein complex purification | Q28131621 |
| | The spliceosome: design principles of a dynamic RNP machine | Q28131809 |
| | Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesis | Q28265874 |
| | Pre-mRNA splicing: awash in a sea of proteins | Q29547272 |
| | Pre-mRNA processing reaches back to transcription and ahead to translation | Q29615045 |
| | Expansion of the eukaryotic proteome by alternative splicing | Q29615083 |
| | Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches | Q29615084 |
| | Allosteric cascade of spliceosome activation | Q29615086 |
| | Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing | Q29620837 |
| | Conformational dynamics of single pre-mRNA molecules during in vitro splicing | Q30053690 |
| | The role of exon sequences in C complex spliceosome structure | Q30491940 |
| | Viewing dynamic assembly of molecular complexes by multi-wavelength single-molecule fluorescence | Q33243370 |
| | Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components | Q33280145 |
| | Visualizing the splicing of single pre-mRNA molecules in whole cell extract | Q33306330 |
| | A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing | Q33838525 |
| | Spliceosome discards intermediates via the DEAH box ATPase Prp43p | Q33933327 |
| | A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis | Q33938648 |
| | A computational analysis of sequence features involved in recognition of short introns | Q33944374 |
| | Mutational analysis of pre-mRNA splicing in Saccharomyces cerevisiae using a sensitive new reporter gene, CUP1 | Q33960716 |
| | Genomewide analysis of mRNA processing in yeast using splicing-specific microarrays | Q34126595 |
| | The spliceosome: the most complex macromolecular machine in the cell? | Q34278742 |
| | Yeast pre-mRNA splicing: methods, mechanisms, and machinery | Q34694763 |
| | Do-it-yourself guide: how to use the modern single-molecule toolkit | Q34782759 |
| | The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome | Q35014709 |
| | Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation | Q35018262 |
| | Real-time observation of transcription initiation and elongation on an endogenous yeast gene | Q35155140 |
| | Diverse environmental stresses elicit distinct responses at the level of pre-mRNA processing in yeast | Q35157735 |
| | Single-molecule imaging of transcriptionally coupled and uncoupled splicing | Q35633440 |
| | Rapid, transcript-specific changes in splicing in response to environmental stress | Q36151037 |
| | Cryo-electron microscopy of spliceosomal components | Q36475417 |
| | Prp43: An RNA helicase-like factor involved in spliceosome disassembly | Q36607359 |
| | Where in the cell is the minor spliceosome? | Q36735152 |
| | The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing | Q37043127 |
| | Exon ligation is proofread by the DExD/H-box ATPase Prp22p | Q37059609 |
| | Spliceosome assembly pathways for different types of alternative splicing converge during commitment to splice site pairing in the A complex. | Q37099916 |
| | "Nought may endure but mutability": spliceosome dynamics and the regulation of splicing | Q37197189 |
| | Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA. | Q37285454 |
| | Identification of alternative splicing regulators by RNA interference in Drosophila | Q37619393 |
| | Cross-talk in transcription, splicing and chromatin: who makes the first call? | Q37791583 |
| | Single molecule enzymology: watching the reaction | Q38351984 |
| | The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells | Q39648201 |
| | Insights into branch nucleophile positioning and activation from an orthogonal pre-mRNA splicing system in yeast | Q39978710 |
| | An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p | Q41607972 |
| | Exon, intron and splice site locations in the spliceosomal B complex | Q42087609 |
| | trans-splicing to spliceosomal U2 snRNA suggests disruption of branch site-U2 pairing during pre-mRNA splicing | Q42381501 |
| | Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome. | Q42679830 |
| | Ordered and dynamic assembly of single spliceosomes | Q42726090 |
| | Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing | Q42914749 |
| | Mechanistic insights from reversible splicing catalysis | Q42953067 |
| | Competition between the ATPase Prp5 and branch region-U2 snRNA pairing modulates the fidelity of spliceosome assembly | Q43049651 |
| | Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes | Q44165085 |
| | Deciphering 3'ss selection in the yeast genome reveals an RNA thermosensor that mediates alternative splicing | Q44838435 |
| | Preparation of fluorescent pre-mRNA substrates for an smFRET study of pre-mRNA splicing in yeast | Q45720413 |
| | Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing | Q45828510 |
| | RBM5/Luca-15/H37 regulates Fas alternative splice site pairing after exon definition. | Q46050971 |
| | Commitment to splice site pairing coincides with A complex formation | Q46357841 |
| | A mechanism to enhance mRNA splicing fidelity: the RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates | Q46565000 |
| | Suppression of multiple substrate mutations by spliceosomal prp8 alleles suggests functional correlations with ribosomal ambiguity mutants | Q47654036 |
| | Reverse self-splicing of group II intron RNAs in vitro | Q47858247 |
| | Isolation of an active step I spliceosome and composition of its RNP core | Q50336090 |
| | Repositioning of the reaction intermediate within the catalytic center of the spliceosome. | Q52568800 |
| | The yeast RNA gene products are essential for mRNA splicing in vitro | Q59198319 |
| | Bimolecular exon ligation by the human spliceosome | Q73407427 |
| | Dynamics of the U1 Small Nuclear Ribonucleoprotein during Yeast Spliceosome Assembly | Q73485917 |
| | Ten commandments of enzymology, amended | Q79165759 |
| | Both catalytic steps of nuclear pre-mRNA splicing are reversible | Q81534595 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | macromolecule | Q178593 |
| | spliceosome | Q915868 |
| P1104 | number of pages | 10 | |
| P304 | page(s) | 179-188 | |
| P577 | publication date | 2012-04-03 | |
| P1433 | published in | Trends in Biochemical Sciences | Q1565711 |
| P1476 | title | The spliceosome: a flexible, reversible macromolecular machine | |
| P478 | volume | 37 | |