Biological activities of toxins A and B of Clostridium difficile

scientific article

Biological activities of toxins A and B of Clostridium difficile is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/IAI.35.3.1147-1150.1982
P932PMC publication ID351167
P698PubMed publication ID7068215

P2093author name stringD M Lyerly
T D Wilkins
S H Richardson
D E Lockwood
P2860cites workPurification and characterization of toxins A and B of Clostridium difficileQ24604972
Pathophysiological effects of Vibrio cholerae and enterotoxigenic Escherichia coli and their exotoxins on eucaryotic cellsQ33623017
Clostridium difficile and the aetiology of pseudomembranous colitisQ34058811
Intestinal fluid accumulation induced by oral challenge with Vibrio cholerae or cholera toxin in infant miceQ34426570
Morphology of experimental antibiotic-associated enterocolitis in the hamster: a model for human pseudomembranous colitis and antibiotic-associated diarrhoeaQ34475487
Production of Vascular Permeability Factor by Enterotoxigenic Escherichia coli Isolated from ManQ34497661
Antibiotic-Associated Pseudomembranous Colitis Due to Toxin-Producing ClostridiaQ34708067
Role of Clostridium difficile in antibiotic-associated pseudomembranous colitisQ38537810
Antibiotic-induced lethal enterocolitis in hamsters: studies with eleven agents and evidence to support the pathogenic role of toxin-producing ClostridiaQ38537827
Partial purification of a toxin found in hamsters with antibiotic-associated colitis. Reversible binding of the toxin by cholestyramineQ39243143
Comparison of two toxins produced by Clostridium difficileQ40612560
Gastrointestinal and systemic toxicity of fecal extracts from hamsters with clindmycin-induced colitisQ40828456
Purification and characterization of Clostridium difficile toxinQ40877544
Clindamycin-induced enterocolitis in hamstersQ41039811
Clostridium difficile in gnotobiotic miceQ41162628
Enterotoxin production of Yersinia enterocolitica strains.Q41540595
Experimental clindamycin-associated colitis in rabbits. Evidence of toxin-mediated mucosal damageQ67251737
Identification of Clostridium difficile as a cause of pseudomembranous colitisQ67288099
Clindamycin-associated colitis due to a toxin-producing species of Clostridium in hamstersQ67697866
Clinical and laboratory observations in Clostridium difficile colitisQ71386018
Effects of Clostridium difficile Toxin on Tissue-Cultured CellsQ72847346
An experimental study of the mechanism of action of Vibriod cholerae on the intestinal mucous membraneQ73363678
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectClostridium difficileQ310543
P304page(s)1147-1150
P577publication date1982-03-01
P1433published inInfection and ImmunityQ6029193
P1476titleBiological activities of toxins A and B of Clostridium difficile
P478volume35

Reverse relations

cites work (P2860)
Q57445886Absence of intestinal secretion on supernatants from macrophages stimulated with Clostridium difficile toxin B on rabbit ileum
Q35710147Active and passive immunization against Clostridium difficile diarrhea and colitis
Q48356396Adaptive immune response to Clostridium difficile infection: A perspective for prevention and therapy
Q35122389Anti-Clostridium difficile bovine immunoglobulin concentrate inhibits cytotoxicity and enterotoxicity of C. difficile toxins.
Q41875678Association between production of toxins A and B and types of Clostridium difficile
Q35117848Asymptomatic neonatal colonisation by Clostridium difficile
Q36961946Binding kinetics of Clostridium difficile toxins A and B to intestinal brush border membranes from infant and adult hamsters
Q77349069Brewer's yeast and Saccharomyces boulardii both attenuate Clostridium difficile-induced colonic secretion in the rat
Q37025852Cell surface binding site for Clostridium difficile enterotoxin: evidence for a glycoconjugate containing the sequence Gal alpha 1-3Gal beta 1-4GlcNAc
Q36970376Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile
Q37144615Characterization of cross-reactive proteins detected by Culturette Brand Rapid Latex Test for Clostridium difficile
Q40638584Characterization of toxin A-negative, toxin B-positive Clostridium difficile isolates from outbreaks in different countries by amplified fragment length polymorphism and PCR ribotyping
Q37011926Characterization of toxins A and B of Clostridium difficile with monoclonal antibodies
Q35370377Clostridial enteric diseases of domestic animals
Q37419825Clostridium difficile 30 years on: what has, or has not, changed and why?
Q27339318Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism
Q41193374Clostridium difficile Toxins TcdA and TcdB Cause Colonic Tissue Damage by Distinct Mechanisms
Q70302615Clostridium difficile and antibiotic-associated colitis in risk patients: 2-month epidemiologic study in an intensive care unit
Q71298919Clostridium difficile and its toxins
Q34003957Clostridium difficile recombinant toxin A repeating units as a carrier protein for conjugate vaccines: studies of pneumococcal type 14, Escherichia coli K1, and Shigella flexneri type 2a polysaccharides in mice
Q40763960Clostridium difficile toxin A carboxyl-terminus peptide lacking ADP-ribosyltransferase activity acts as a mucosal adjuvant.
Q43220463Clostridium difficile toxin A induces a specific antisecretory factor which protects against intestinal mucosal damage
Q30452844Clostridium difficile toxin A induces the release of neutrophil chemotactic factors from rat peritoneal macrophages: role of interleukin-1beta, tumor necrosis factor alpha, and leukotrienes.
Q24561503Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers
Q35589374Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes
Q67732507Clostridium difficile toxin B disrupts the barrier function of T84 monolayers
Q35619086Clostridium difficile toxin B intoxicated mouse colonic epithelial CT26 cells stimulate the activation of dendritic cells.
Q34214675Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro
Q40159699Clostridium difficile toxins A and B inhibit human immune response in vitro
Q36640296Clostridium difficile: clinical disease and diagnosis
Q24617347Clostridium difficile: its disease and toxins
Q40144039Comparison of culture, cytotoxin assay and two EIA tests with clinical diagnosis of Clostridium difficile-associated diarrhea
Q40178561Comparison of four commercially available rapid enzyme immunoassays with cytotoxin assay for detection of Clostridium difficile toxin(s) from stool specimens.
Q36959185Construction and expression of the complete Clostridium difficile toxin A gene in Escherichia coli
Q55279053Cysteine Protease-Mediated Autocleavage of Clostridium difficile Toxins Regulates Their Proinflammatory Activity.
Q68875632Detection of Clostridium difficile Toxin A by immunoblotting
Q37246483Development of a rapid enzyme immunoassay for Clostridium difficile toxin A and its use in the diagnosis of C. difficile-associated disease
Q40160408Effect of Clostridium difficile enterotoxin A on ultrastructure of Chinese hamster ovary cells
Q30446178Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis
Q36492515Effect of toxin A and B of Clostridium difficile on rabbit ileum and colon
Q37021640Effect of various diets on toxin production by two strains of Clostridium difficile in gnotobiotic mice
Q52653036Effects of Clostridium difficile toxin A on K562/A02 cell proliferation, apoptosis and multi-drug resistance.
Q24651060Effects of Clostridium difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitro
Q37074797Effects of Clostridium difficile toxins given intragastrically to animals
Q40673310Effects of anti-inflammatory drugs on fever and neutrophilia induced by Clostridium difficile toxin B.
Q36441243Effects of the two toxins of Clostridium difficile in antibiotic-associated cecitis in hamsters.
Q36996688Emergence in gnotobiotic mice of nontoxinogenic clones of Clostridium difficile from a toxinogenic one
Q30449794Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion
Q42146936Enterotoxic activity of Klebsiella oxytoca cytotoxin in rabbit intestinal loops.
Q34601691Enterotoxigenicity of mature 45-kilodalton and processed 35-kilodalton forms of hemagglutinin protease purified from a cholera toxin gene-negative Vibrio cholerae non-O1, non-O139 strain
Q40216280Enzyme immunoassay for detection of antibody to toxins A and B of Clostridium difficile
Q24652980Enzyme-linked immunosorbent assay for Clostridium difficile toxin A
Q44737713Epidemiology of Clostridium difficile infection in a large teaching hospital in Singapore
Q39867842Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-alpha by macrophages
Q68046188Evaluation of an enzyme immunoassay for detection of Clostridium difficile toxin A
Q37305492Evaluation of the usefulness of counterimmunoelectrophoresis for diagnosis of Clostridium difficile-associated colitis in clinical specimens
Q30850682Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium
Q67667110Fast purification of Clostridium sordellii cytotoxin
Q52581850Fucoidin prevents Clostridium difficile toxin-A-induced ileal enteritis in mice.
Q42142150Harnessing the glucosyltransferase activities of Clostridium difficile for functional studies of toxins A and B.
Q24676013Human antibody response to Clostridium difficile toxin A in relation to clinical course of infection
Q46911443Ileal smooth muscle motility depression on rabbit induced by toxin A from Clostridium difficile
Q36630071Immunogenicity and protective efficacy of Clostridium difficile spore proteins
Q33866797Immunogenicity of a Salmonella typhimurium aroA aroD vaccine expressing a nontoxic domain of Clostridium difficile toxin A.
Q61806523Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027
Q89551586Insights into the Role of Human Gut Microbiota in Clostridioides difficile Infection
Q40155029Interaction of Clostridium difficile toxin A with cultured cells: cytoskeletal changes and nuclear polarization
Q39748439International typing study of toxin A-negative, toxin B-positive Clostridium difficile variants
Q35841034Intravenous immunoglobulin therapy for severe Clostridium difficile colitis
Q39606562Laboratory diagnosis of Clostridium difficile-associated diarrhoea
Q36946424Localization of two epitopes recognized by monoclonal antibody PCG-4 on Clostridium difficile toxin A
Q67919635Lower Intestinal Bleeding in the Elderly
Q36657238Modulation of cytotoxin production by Clostridium difficile in the intestinal tracts of gnotobiotic mice inoculated with various human intestinal bacteria
Q37274931Monoclonal and specific polyclonal antibodies for immunoassay of Clostridium difficile toxin A
Q40012214Multicenter evaluation of four methods for Clostridium difficile detection: ImmunoCard C. difficile, cytotoxin assay, culture, and latex agglutination
Q24607564Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit
Q30434555New developments in enteric bacterial toxins
Q39663975Novel one-step method for detection and isolation of active-toxin-producing Clostridium difficile strains directly from stool samples
Q37067252Open-label, dose escalation phase I study in healthy volunteers to evaluate the safety and pharmacokinetics of a human monoclonal antibody to Clostridium difficile toxin A.
Q36965686Passive immunization of hamsters against disease caused by Clostridium difficile by use of bovine immunoglobulin G concentrate
Q39664770Prevalence and genetic characterization of toxin A variant strains of Clostridium difficile among adults and children with diarrhea in France
Q35044119Progress in the discovery of treatments for C. difficile infection: A clinical and medicinal chemistry review.
Q36347003Pseudomembranous colitis in Clostridium difficile-monoassociated rats.
Q37004400Purification and characterization of Clostridium sordellii hemorrhagic toxin and cross-reactivity with Clostridium difficile toxin A (enterotoxin).
Q33602753Purification and characterization of alpha-toxin produced by Clostridium novyi type A
Q36942789Purification and characterization of an enterotoxin from Bacteroides fragilis
Q24604972Purification and characterization of toxins A and B of Clostridium difficile
Q37021851Purification of Clostridium difficile toxin A by affinity chromatography on immobilized thyroglobulin
Q54566485Role of tumor necrosis factor and nitric oxide in the cytotoxic effects of Clostridium difficile toxin A and toxin B on macrophages.
Q37098464Sealed adult mice: new model for enterotoxin evaluation
Q68199126Sensitivity in culture of epithelial cells from rhesus monkey kidney and human colon carcinoma to toxins A and B from Clostridium difficile
Q33673934Survey of incidence of Clostridium difficile infection in Canadian hospitals and diagnostic approaches.
Q40225012Survey of the extrachromosomal gene pool of Clostridium difficile
Q35131944Survival of anti-Clostridium difficile bovine immunoglobulin concentrate in the human gastrointestinal tract.
Q26775010The Role of Rho GTPases in Toxicity of Clostridium difficile Toxins
Q37954308The enterotoxicity of Clostridium difficile toxins
Q73519442The involvement of macrophage-derived tumour necrosis factor and lipoxygenase products on the neutrophil recruitment induced by Clostridium difficile toxin B
Q24562382The low molecular mass GTP-binding protein Rho is affected by toxin A from Clostridium difficile
Q49282081The role of purified Clostridium difficile glucosylating toxins in disease pathogenesis utilizing a murine cecum injection model
Q47734724The role of toxins in Clostridium difficile infection.
Q34623572The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection
Q92458052The xenobiotic sensing pregnane X receptor regulates tissue damage and inflammation triggered by C difficile toxins
Q35872353Time-resolved amino acid uptake of Clostridium difficile 630Δerm and concomitant fermentation product and toxin formation
Q38899041Tolevamer, an anionic polymer, neutralizes toxins produced by the BI/027 strains of Clostridium difficile
Q36159563Toward a structural understanding of Clostridium difficile toxins A and B.
Q33590965Toxin gene analysis of a variant strain of Clostridium difficile that causes human clinical disease
Q40668497Translocation of Clostridium difficile toxin B across polarized Caco-2 cell monolayers is enhanced by toxin A.
Q34880915Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin
Q40220668Two bacteriophages of Clostridium difficile.
Q37680481Variations in virulence and molecular biology among emerging strains of Clostridium difficile
Q42010469Yield of stool culture with isolate toxin testing versus a two-step algorithm including stool toxin testing for detection of toxigenic Clostridium difficile

Search more.