Activation of the neurokinin-1 receptor by substance P triggers the release of substance P from cultured adult rat dorsal root ganglion neurons

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Activation of the neurokinin-1 receptor by substance P triggers the release of substance P from cultured adult rat dorsal root ganglion neurons is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1018635361
P356DOI10.1186/1744-8069-3-42
P932PMC publication ID2235838
P698PubMed publication ID18157919
P5875ResearchGate publication ID5691241

P50authorYu-Sang LiQ43125008
He-Bin TangQ57049791
Koji ArihiroQ100731130
Yoshihiro NakataQ117843641
P2860cites workDelineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptorQ24619237
Myofilament anchoring of protein kinase C-epsilon in cardiac myocytesQ28252357
Structure, expression, and some regulatory mechanisms of the rat preprotachykinin gene encoding substance P, neurokinin A, neuropeptide K, and neuropeptide gammaQ28262382
Distinct mechanism for antidepressant activity by blockade of central substance P receptorsQ28281932
Primary afferent tachykinins are required to experience moderate to intense painQ28506575
Neurokinin-1 receptor enhances TRPV1 activity in primary sensory neurons via PKCepsilon: a novel pathway for heat hyperalgesiaQ28569084
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functionsQ29547189
Peptide autoreceptors: does an autoreceptor for substance P exist?Q33781838
The neuropeptide substance P activates p38 mitogen-activated protein kinase resulting in IL-6 expression independently from NF-kappa B.Q33924460
The role of substance P in stress and anxiety responsesQ33997424
Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesiaQ34208152
Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and miceQ35042293
Substance P increases neutrophil adhesion to human umbilical vein endothelial cellsQ35045505
Substance P stimulates cyclooxygenase-2 and prostaglandin E2 expression through JAK-STAT activation in human colonic epithelial cellsQ36994010
Amyloid beta peptide (25-35) activates protein kinase C leading to cyclooxygenase-2 induction and prostaglandin E2 release in primary midbrain astrocytes.Q40483597
Tachykinin receptors: a radioligand binding perspective.Q40853954
Intrathecal substance P-induced thermal hyperalgesia and spinal release of prostaglandin E2 and amino acidsQ41613425
The long-term exposure of rat cultured dorsal root ganglion cells to bradykinin induced the release of prostaglandin E2 by the activation of cyclooxygenase-2.Q42492857
PGE(2) increases release of substance P from renal sensory nerves by activating the cAMP-PKA transduction cascadeQ43993537
Involvement of p38 and JNK MAPKs pathways in Substance P-induced production of TNF-alpha by peritoneal mast cellsQ44049735
Substance P-induced activation of p42/44 mitogen-activated protein kinase associated with cell proliferation in human tracheal smooth muscle cellsQ44130932
Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons.Q45056215
CB(1) cannabinoid receptor stimulation modulates transient receptor potential vanilloid receptor 1 activities in calcium influx and substance P Release in cultured rat dorsal root ganglion cells.Q45305582
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibitionQ46223466
Olopatadine attenuates the enhancement of capsaicin-evoked substance P release by bradykinin from cultured dorsal root ganglion neurons.Q46351136
Zaltoprofen inhibits bradykinin-induced responses by blocking the activation of second messenger signaling cascades in rat dorsal root ganglion cells.Q46460606
Loperamide inhibits tachykinin NK3-receptor-triggered serotonin release without affecting NK2-receptor-triggered serotonin release from guinea pig colonic mucosaQ46533546
Inhibition of spinal protein kinase C blocks substance P-mediated hyperalgesiaQ46973494
Effects of habenular lesions on the substance P content of various brain regionsQ48343030
Small sensory neurons in the rat dorsal root ganglia express functional NK-1 tachykinin receptorQ48388874
Evidence for the existence of substance P autoreceptor in the membrane of rat dorsal root ganglion neurons.Q53972267
Cultured rat sensory neurones express functional tachykinin receptor subtypes 1, 2 and 3.Q54380858
Substance P release evoked by capsaicin or potassium from rat cultured dorsal root ganglion neurons is conversely modulated with bradykinin.Q64917455
A Potent Nonpeptide Antagonist of the Substance P (NK 1 ) ReceptorQ67679280
Interleukin-1beta induces substance P release from primary afferent neurons through the cyclooxygenase-2 systemQ73120805
Capsaicin-stimulated release of substance P from cultured dorsal root ganglion neurons: involvement of two distinct mechanismsQ73634933
Substance PQ74220103
Glucagon-like peptide 1 activates protein kinase C through Ca2+-dependent activation of phospholipase C in insulin-secreting cellsQ79998841
P407language of work or nameEnglishQ1860
P921main subjectsubstance PQ411041
P304page(s)42
P577publication date2007-12-25
P1433published inMolecular PainQ15766244
P1476titleActivation of the neurokinin-1 receptor by substance P triggers the release of substance P from cultured adult rat dorsal root ganglion neurons
P478volume3

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cites work (P2860)
Q50027724A Nociceptive Role for Integrin Signaling in Pain After Mechanical Injury to the Spinal Facet Capsular Ligament
Q34720115Activation of CaMKII and ERK1/2 contributes to the time-dependent potentiation of Ca2+ response elicited by repeated application of capsaicin in rat DRG neurons
Q43701447Activation of transient receptor potential ankyrin 1 evokes nociception through substance P release from primary sensory neurons.
Q41850845Effects of NSAIDs and paracetamol (acetaminophen) on protein kinase C epsilon translocation and on substance P synthesis and release in cultured sensory neurons
Q42426842Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways
Q58749497Extract of the Blood Circulation-Promoting Recipe-84 Can Protect Rat Retinas by Inhibiting the β-Catenin Signaling Pathway
Q93213096Intracellular emetic signaling cascades by which the selective neurokinin type 1 receptor (NK1R) agonist GR73632 evokes vomiting in the least shrew (Cryptotis parva)
Q38333909Neuronal Fc gamma receptor I as a novel mediator for IgG immune complex-induced peripheral sensitization
Q35147369Neuronal Fc-gamma receptor I mediated excitatory effects of IgG immune complex on rat dorsal root ganglion neurons.
Q42728412Nimesulide inhibits protein kinase C epsilon and substance P in sensory neurons - comparison with paracetamol
Q36845421Nutmeg oil alleviates chronic inflammatory pain through inhibition of COX-2 expression and substance P release in vivo
Q30519202Reactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neurons
Q41376512Resolvin E1 Inhibits Substance P-Induced Potentiation of TRPV1 in Primary Sensory Neurons
Q41950284Role of fosaprepitant, a neurokinin Type 1 receptor antagonist, in morphine-induced antinociception in rats
Q41635275Substance P is increased in patients with sickle cell disease and associated with haemolysis and hydroxycarbamide use.
Q34459294Synergism between methamphetamine and the neuropeptide substance P on the production of nitric oxide in the striatum of mice
Q37118783TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis
Q35749792The effect of spinal cord injury on the neurochemical properties of vagal sensory neurons
Q36219440Transient receptor potential canonical 3 (TRPC3) is required for IgG immune complex-induced excitation of the rat dorsal root ganglion neurons
Q35656935Up-Regulation of the Biosynthesis and Release of Substance P through Wnt/β-Catenin Signaling Pathway in Rat Dorsal Root Ganglion Cells
Q38375846n-3 Polyunsaturated fatty acids and mast cell activation
Q34772099β-catenin accumulation in nuclei of hepatocellular carcinoma cells up-regulates glutathione-s-transferase M3 mRNA.

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