Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.

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Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JAUT.2012.07.007
P932PMC publication ID3516707
P698PubMed publication ID22921335
P5875ResearchGate publication ID230743176

P50authorNikolaus ThuilleQ43291712
Natascha Hermann-KleiterQ120598795
P2093author name stringGottfried Baier
Mathias Müller
Andreas Katopodis
Friedrich Fresser
Lukas Roth
Marlies Meisel
P2860cites workTGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat functionQ24314628
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Generation of pathogenic T(H)17 cells in the absence of TGF-β signallingQ24625230
Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5Q24635387
The AP-1 transcription factor Batf controls T(H)17 differentiationQ24644525
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cellsQ24655629
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TH17 cells in development: an updated view of their molecular identity and genetic programmingQ28276449
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cellsQ28296956
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gammaQ28506783
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineagesQ29547871
Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokinesQ33500916
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Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitisQ34093829
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T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitisQ34107156
Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiationQ34519854
IL-21 signaling is critical for the development of type I diabetes in the NOD mouseQ34823699
Transcriptional regulation of the Th17 immune response by IKK(alpha)Q35102214
Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3.Q35117339
1,25-dihydroxyvitamin D(3) ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A.Q35192119
Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2.Q35724805
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.Q36189566
Ets-1 is a negative regulator of Th17 differentiationQ36229174
Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cellsQ36652900
The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancerQ36897846
The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunityQ37087730
Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.Q37106760
Critical regulation of early Th17 cell differentiation by interleukin-1 signalingQ37250727
Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expressionQ37295003
The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunityQ37377446
Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinaseQ37399188
Transcriptional regulatory networks in Th17 cell differentiationQ37425866
Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cellsQ37736265
Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammatQ39988736
T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype.Q42742129
TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cellsQ43532692
PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradationQ44764543
Crucial role for nuclear factor of activated T cells in T cell receptor-mediated regulation of human interleukin-17.Q45086536
Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their ExpansionQ57202941
IκBζ regulates TH17 development by cooperating with ROR nuclear receptorsQ59067213
Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiationQ79544847
T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunityQ79609622
[The progresses of research on SOCS family in the central nervous system]Q79932783
[Foxp3-transfected CD4+ CD25- T cells suppress function of dendritic cells]Q80810244
Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesoderminQ84159819
P433issue4
P304page(s)428-440
P577publication date2012-08-24
P1433published inJournal of AutoimmunityQ15716783
P1476titleNuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter
P478volume39