Inhibition of APOBEC3G activity impedes double-stranded DNA repair

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Inhibition of APOBEC3G activity impedes double-stranded DNA repair is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/FEBS.13556
P932PMC publication ID4712096
P698PubMed publication ID26460502
P5875ResearchGate publication ID282874624

P50authorElena Britan-RosichQ71770161
P2093author name stringCelia A Schiffer
Moshe Kotler
Shivender M D Shandilya
Ponnandy Prabhu
Adi Nagler
P2860cites workAn anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22Q24292358
APOBEC3 proteins mediate the clearance of foreign DNA from human cellsQ24294583
Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.Q24311896
Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfacesQ24599263
Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysisQ39762406
Hypermutation by intersegmental transfer of APOBEC3G cytidine deaminaseQ39935230
Explaining differences in sensitivity to killing by ionizing radiation between human lymphoid cell linesQ41025975
A radioresistant variant derived from a human neuroblastoma cell line is less prone to radiation-induced apoptosisQ41278436
Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif.Q42152378
Evaluation of the radioprotective effects of propolis and flavonoids in gamma-irradiated mice: the alkaline comet assay studyQ46822654
Adaptive response to DNA-damaging agents: a review of potential mechanismsQ48031361
The effect of aging on the DNA damage and repair capacity in 2BS cells undergoing oxidative stress.Q54373923
The DNA-damage response in human biology and diseaseQ24606586
First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3GQ24615552
Mutational processes molding the genomes of 21 breast cancersQ24620915
HIV-1 Vif, APOBEC, and intrinsic immunityQ24647833
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray dosesQ24677973
The APOBEC3 family of retroelement restriction factorsQ26862780
Crystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding DomainQ27678176
NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificityQ27678249
The APOBEC3C crystal structure and the interface for HIV-1 Vif bindingQ27682427
The DNA damage response: putting checkpoints in perspectiveQ28131713
Lessons from hereditary colorectal cancerQ28131788
Retroviral restriction by APOBEC proteinsQ28290721
A simple technique for quantitation of low levels of DNA damage in individual cellsQ29014320
The patterns and dynamics of genomic instability in metastatic pancreatic cancerQ29618121
Human cancers express mutator phenotypes: origin, consequences and targetingQ33554201
Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeuticsQ33815187
APOBEC3G inhibits HIV-1 RNA elongation by inactivating the viral trans-activation response elementQ34052968
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancerQ34062924
Multiple mutations and cancerQ34327554
Repair of naturally occurring mismatches can induce mutations in flanking DNA.Q34420649
APOBEC3A can activate the DNA damage response and cause cell-cycle arrestQ34953340
Multifaceted counter-APOBEC3G mechanisms employed by HIV-1 Vif.Q35113622
APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasisQ35484686
Single-stranded DNA scanning and deamination by APOBEC3G cytidine deaminase at single molecule resolution.Q35939875
Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.Q35992079
Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family.Q36081987
APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repairQ36100420
DNA deamination in immunity: AID in the context of its APOBEC relatives.Q36845658
A computational analysis of the structural determinants of APOBEC3's catalytic activity and vulnerability to HIV-1 Vif.Q36871140
APOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotionQ36941097
The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelementsQ37096085
The expression of 16 genes related to the cell of origin and immune response predicts survival in elderly patients with diffuse large B-cell lymphoma treated with CHOP and rituximab.Q37174123
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.Q37345878
18F-FDG uptake rate is a biomarker of eosinophilic inflammation and airway response in asthmaQ37374625
Oligomerization transforms human APOBEC3G from an efficient enzyme to a slowly dissociating nucleic acid-binding protein.Q37631430
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)112-129
P577publication date2015-10-13
P1433published inFEBS JournalQ1388041
P1476titleInhibition of APOBEC3G activity impedes double-stranded DNA repair
P478volume283

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Q38790689Reassessing APOBEC3G Inhibition by HIV-1 Vif-Derived Peptidescites workP2860

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