APOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotion

scientific article published on 18 April 2013

APOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/0008-5472.CAN-13-0728
P932PMC publication ID3686885
P698PubMed publication ID23598277

P2093author name stringMoshe Kotler
Roni Nowarski
P2860cites workAn anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22Q24292358
APOBEC3 proteins mediate the clearance of foreign DNA from human cellsQ24294583
Post-replicative base excision repair in replication fociQ24534209
Mutational processes molding the genomes of 21 breast cancersQ24620915
Human CtIP promotes DNA end resectionQ24646062
HIV-1 Vif, APOBEC, and intrinsic immunityQ24647833
Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPAQ27628426
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processingQ27929897
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1Q27938100
Lessons from hereditary colorectal cancerQ28131788
Regulation of DNA double-strand break repair pathway choiceQ28262730
Retroviral restriction by APOBEC proteinsQ28290721
Cytidine deamination of retroviral DNA by diverse APOBEC proteinsQ28578747
Hypermutation of an ancient human retrovirus by APOBEC3GQ28757351
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaksQ29465538
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaksQ29614215
Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damageQ29614221
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break endsQ29615269
The patterns and dynamics of genomic instability in metastatic pancreatic cancerQ29618121
BRCA2 is required for homology-directed repair of chromosomal breaksQ29618799
HIV-1 accessory proteins--ensuring viral survival in a hostile environmentQ29619538
The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammalsQ33385376
Human cancers express mutator phenotypes: origin, consequences and targetingQ33554201
Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targetingQ33582128
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequencesQ34081887
Multiple mutations and cancerQ34327554
B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracilQ34427857
RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycleQ34537165
Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolismQ34720629
APOBEC3A can activate the DNA damage response and cause cell-cycle arrestQ34953340
Focus on lymphomasQ35008948
APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasisQ35484686
Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.Q35992079
APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repairQ36100420
Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3AQ36298528
Inducible DNA breaks in Ig S regions are dependent on AID and UNGQ36402801
The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells.Q36490746
Differential usage of non-homologous end-joining and homologous recombination in double strand break repairQ36522562
DNA deamination in immunity: AID in the context of its APOBEC relatives.Q36845658
Role of AID in tumorigenesisQ36845685
The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelementsQ37096085
The expression of 16 genes related to the cell of origin and immune response predicts survival in elderly patients with diffuse large B-cell lymphoma treated with CHOP and rituximab.Q37174123
APOBEC3B is an enzymatic source of mutation in breast cancer.Q37533713
Live imaging of induced and controlled DNA double-strand break formation reveals extremely low repair by homologous recombination in human cellsQ39439217
APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.Q40464899
APOBEC3 proteins and genomic stability: the high cost of a good defenseQ40848214
DNA helicases Sgs1 and BLM promote DNA double-strand break resectionQ42750184
A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.Q46255308
Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancersQ46437306
MRE11/RAD50 cleaves DNA in the AID/UNG-dependent pathway of immunoglobulin gene diversificationQ46802323
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)3494-3498
P577publication date2013-04-18
P1433published inCancer ResearchQ326097
P1476titleAPOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotion
P478volume73

Reverse relations

cites work (P2860)
Q28085553AID/APOBEC deaminases and cancer
Q34992751APOBEC3A functions as a restriction factor of human papillomavirus
Q58764658APOBEC3B Activity Is Prevalent in Urothelial Carcinoma Cells and Only Slightly Affected by LINE-1 Expression
Q33743603APOBEC3B, a molecular driver of mutagenesis in human cancers
Q41552553APOBEC3G acts as a therapeutic target in mesenchymal gliomas by sensitizing cells to radiation-induced cell death
Q96606908Activation of DNA damage repair factors in HPV positive oropharyngeal cancers
Q34062924Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer
Q40513376Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors
Q45881268Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells.
Q88427699DNA Methylation-a Potential Source of Mitochondria DNA Base Mismatch in the Development of Diabetic Retinopathy
Q38723760Elucidation of the genetic and epigenetic landscape alterations in RNA binding proteins in glioblastoma
Q57174223Expressed HNSCC variants by HPV-status in a well-characterized Michigan cohort
Q90815056Genomic heterogeneity in bladder cancer: challenges and possible solutions to improve outcomes
Q40125151Global Mapping of the Macrophage-HIV-1 Transcriptome Reveals that Productive Infection Induces Remodeling of Host Cell DNA and Chromatin
Q104492841HIV-2 Vif and foamy virus Bet antagonize APOBEC3B by different mechanisms
Q39852184Increased APOBEC3B Predicts Worse Outcomes in Lung Cancer: A Comprehensive Retrospective Study
Q36460087Inhibition of APOBEC3G activity impedes double-stranded DNA repair
Q36265144Progressive APOBEC3B mRNA expression in distant breast cancer metastases.
Q61812531RNA Editors, Cofactors, and mRNA Targets: An Overview of the C-to-U RNA Editing Machinery and Its Implication in Human Disease
Q40076776Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression
Q37518666Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties
Q88548676Treatment resistance in urothelial carcinoma: an evolutionary perspective
Q47568875Viral subversion of APOBEC3s: Lessons for anti-tumor immunity and tumor immunotherapy

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