Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells.

scientific article

Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1371/JOURNAL.PGEN.1007051
P932PMC publication ID5656329
P698PubMed publication ID29028794

P50authorPaul L FoxQ56939534
Michelle S LongworthQ56939548
Kommireddy VasuQ56939565
Peter A LarsonQ89628028
P2093author name stringJohn V Moran
Dalia Halawani
Belinda Willard
Dongmei Zhang
Emily Deutschman
Jacqueline R Ward
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
Characterization of LINE-1 ribonucleoprotein particlesQ21092434
Condensin II promotes the formation of chromosome territories by inducing axial compaction of polyploid interphase chromosomesQ21144911
Identification of genes that promote or antagonize somatic homolog pairing using a high-throughput FISH-based screenQ21144920
L13a blocks 48S assembly: role of a general initiation factor in mRNA-specific translational controlQ24292991
Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cellsQ24297107
Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production.Q38757484
LINE-1 Cultured Cell Retrotransposition AssayQ38792667
Haploinsufficiency of an RB-E2F1-Condensin II complex leads to aberrant replication and aneuploidyQ39003315
Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE-1 retrotransposonQ39457323
Determination of L1 retrotransposition kinetics in cultured cellsQ39586006
Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequenceQ39855931
Efficient translation initiation directed by the 900-nucleotide-long and GC-rich 5' untranslated region of the human retrotransposon LINE-1 mRNA is strictly cap dependent rather than internal ribosome entry site mediatedQ40139032
Twin priming: a proposed mechanism for the creation of inversions in L1 retrotranspositionQ40415833
Functional reverse transcriptase encoded by the human LINE-1 from baculovirus-infected insect cellsQ40662096
Isolation of an active human transposable elementQ42614185
Cis-preferential LINE-1 reverse transcriptase activity in ribonucleoprotein particlesQ42688858
A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertionQ42693461
RNA truncation by premature polyadenylation attenuates human mobile element activityQ42833909
LINE-1 retrotransposition: impact on genome stability and diversity and human diseaseQ43092307
Efficient supercoiling of DNA by a single condensin complex as revealed by electron spectroscopic imagingQ44042955
A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis.Q47071869
Many human genes are transcribed from the antisense promoter of L1 retrotransposonQ48306054
A chromatin insulator determines the nuclear localization of DNA.Q52584471
A transient assay reveals that cultured human cells can accommodate multiple LINE-1 retrotransposition events.Q53905712
hCAP-D3 Expression Marks a Prostate Cancer Subtype With Favorable Clinical Behavior and Androgen Signaling SignatureQ60691593
Ty elements transpose through an RNA intermediateQ70078812
Identification of critical CpG sites for repression of L1 transcription by DNA methylationQ73378476
Genomic deletions created upon LINE-1 retrotranspositionQ74604693
Human l1 retrotransposition is associated with genetic instability in vivoQ74604697
Cancers Complicating Inflammatory Bowel DiseaseQ85556516
Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational controlQ24298100
Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translationQ24306776
Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotranspositionQ24309049
LINE-1 ORF1 protein localizes in stress granules with other RNA-binding proteins, including components of RNA interference RNA-induced silencing complexQ24309597
DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expressionQ24313051
Ribonucleoprotein particle formation is necessary but not sufficient for LINE-1 retrotranspositionQ24336732
Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genesQ24550997
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in CancerQ24608391
Condensins: universal organizers of chromosomes with diverse functionsQ24617958
The Vienna RNA websuiteQ24646014
Two-site phosphorylation of EPRS coordinates multimodal regulation of noncanonical translational control activityQ24646890
Trex1 prevents cell-intrinsic initiation of autoimmunityQ24648757
Analysis of repetitive element DNA methylation by MethyLightQ24814952
Restricting retrotransposons: a reviewQ26741496
Crossing the LINE Toward Genomic Instability: LINE-1 Retrotransposition in CancerQ26770538
The Influence of LINE-1 and SINE Retrotransposons on Mammalian GenomesQ26851352
Trimeric structure and flexibility of the L1ORF1 protein in human L1 retrotranspositionQ27671601
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
Human L1 retrotransposon encodes a conserved endonuclease required for retrotranspositionQ28114795
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene listsQ28131785
Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at nightQ28241693
Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotranspositionQ28297748
L1 retrotransposons, cancer stem cells and oncogenesisQ28394080
The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu RetrotranspositionQ28547090
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3LQ28585211
LINE-1 elements in structural variation and diseaseQ28654758
RNase L restricts the mobility of engineered retrotransposons in cultured human cellsQ28660459
Landscape of somatic retrotransposition in human cancersQ29617664
Reverse Transcriptase Encoded by a Human Transposable ElementQ29618213
High frequency retrotransposition in cultured mammalian cellsQ29618259
Cytosine methylation and the ecology of intragenomic parasitesQ29618264
Human LINE retrotransposons generate processed pseudogenesQ29618327
Human L1 retrotransposition: cis preference versus trans complementationQ29618363
Biology of mammalian L1 retrotransposonsQ29618630
Natural mutagenesis of human genomes by endogenous retrotransposonsQ29619443
Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosisQ33377468
WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expressionQ33642469
Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adultsQ33684572
Translation of LINE-1 DNA elements in vitro and in human cellsQ33785234
Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencingQ33839390
HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functionsQ33922394
Multiple fates of L1 retrotransposition intermediates in cultured human cells.Q33925050
Human L1 retrotransposition: insights and peculiarities learned from a cultured cell retrotransposition assayQ34010455
Translational silencing of ceruloplasmin requires the essential elements of mRNA circularization: poly(A) tail, poly(A)-binding protein, and eukaryotic translation initiation factor 4GQ34012243
Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivoQ34132565
Human L1 element target-primed reverse transcription in vitroQ34207225
Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancerQ34233218
LINE-1 hypomethylation in blood and tissue samples as an epigenetic marker for cancer risk: a systematic review and meta-analysisQ34282505
Spatial and temporal regulation of Condensins I and II in mitotic chromosome assembly in human cells.Q34321072
Unconventional translation of mammalian LINE-1 retrotransposons.Q34324122
Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1.Q34371066
Distinct functions of condensin I and II in mitotic chromosome assemblyQ34372373
Mutation analysis in the BRCA2 gene in primary breast cancersQ34381070
MOV10 RNA helicase is a potent inhibitor of retrotransposition in cellsQ34456088
Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactionsQ34475839
Insulator function and topological domain border strength scale with architectural protein occupancyQ34485099
Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man.Q34553577
Condensins: organizing and segregating the genomeQ34556670
Condensin mutations and abnormal chromosomal structures in pyothorax-associated lymphomaQ34626529
The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin IIQ34628585
Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisionsQ34634010
L1 retrotransposition in nondividing and primary human somatic cellsQ34650044
Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexesQ34667055
Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosisQ34679213
Condensin II mutation causes T-cell lymphoma through tissue-specific genome instabilityQ34679227
ERCC1/XPF limits L1 retrotranspositionQ34768580
Chromosome alignment and transvection are antagonized by condensin II.Q34890028
Condensin II subunit dCAP-D3 restricts retrotransposon mobilization in Drosophila somatic cellsQ35034310
Transcriptional landscape of repetitive elements in normal and cancer human cellsQ35204880
Widespread rearrangement of 3D chromatin organization underlies polycomb-mediated stress-induced silencingQ35470559
The Broad-Spectrum Antiviral Protein ZAP Restricts Human RetrotranspositionQ35639494
Chromosome-associated protein D3 promotes bacterial clearance in human intestinal epithelial cells by repressing expression of amino acid transportersQ35655815
SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation.Q35680916
Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNAQ35844482
Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2.Q35943987
Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolutionQ36084302
Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retrovirusesQ36127858
Architectural proteins, transcription, and the three-dimensional organization of the genomeQ36137518
Two additional potential retrotransposons isolated from a human L1 subfamily that contains an active retrotransposable elementQ36416853
RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3Q36585506
Widespread RNA binding by chromatin-associated proteinsQ36587843
hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotranspositionQ36668906
Translation of the human LINE-1 element, L1HsQ36712171
Cell division promotes efficient retrotransposition in a stable L1 reporter cell lineQ36715813
The GAIT system: a gatekeeper of inflammatory gene expression.Q36798907
Many human L1 elements are capable of retrotranspositionQ36859141
APOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotionQ36941097
A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancerQ36959154
The MOV10 helicase inhibits LINE-1 mobility.Q37175149
Protein-protein interactions and multi-component complexes of aminoacyl-tRNA synthetasesQ38144988
Studies on p40, the leucine zipper motif-containing protein encoded by the first open reading frame of an active human LINE-1 transposable elementQ38325406
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P304page(s)e1007051
P577publication date2017-10-13
P1433published inPLOS GeneticsQ1893441
P1476titleCondensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells
P478volume13

Reverse relations

cites work (P2860)
Q58554665Condensin action and compaction
Q91595880Recurrent Losses and Rapid Evolution of the Condensin II Complex in Insects
Q52324535Structural control of caspase-generated glutamyl-tRNA synthetase by appended noncatalytic WHEP domains.
Q52691403Subunits of human condensins are potential therapeutic targets for cancers.

Search more.