DNA methylation status as a biomarker of anti-epidermal growth factor receptor treatment for metastatic colorectal cancer

scientific article

DNA methylation status as a biomarker of anti-epidermal growth factor receptor treatment for metastatic colorectal cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/CAS.12827
P932PMC publication ID4714671
P698PubMed publication ID26426205

P50authorHiroyuki AburataniQ87657008
P2093author name stringYasuhide Yamada
Naoki Takahashi
Hidekazu Takahashi
Shin Takahashi
Chikashi Ishioka
Masanobu Takahashi
Kenji Tatsuno
Hideki Shimodaira
Kota Ouchi
Shingo Tsuji
P2860cites workGlobal cancer statisticsQ22241238
CpG island methylator phenotype in colorectal cancerQ24672170
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancerQ27851407
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.Q27851422
K-ras mutations and benefit from cetuximab in advanced colorectal cancer.Q27851454
Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancerQ27851456
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysisQ27851573
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancerQ27860681
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trialQ28036747
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR studyQ28189472
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancerQ28240089
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancerQ28271324
Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancerQ28298328
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancerQ29614277
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancerQ29616236
Three DNA methylation epigenotypes in human colorectal cancerQ33520394
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancerQ33913953
A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer.Q34282412
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study.Q34590731
Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer.Q34624122
PEAK: a randomized, multicenter phase II study of panitumumab plus modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) or bevacizumab plus mFOLFOX6 in patients with previously untreated, unresectable, wild-type KRAS exon 2 metastatic colorQ34660907
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trialQ34663697
Genome-scale analysis of aberrant DNA methylation in colorectal cancerQ35694387
CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studiesQ35760749
Advanced colorectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-upQ37489147
The role of the CpG island methylator phenotype in colorectal cancer prognosis depends on microsatellite instability screening statusQ38417609
A phase I/II study of decitabine in combination with panitumumab in patients with wild-type (wt) KRAS metastatic colorectal cancerQ39450048
DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLightQ39853397
Phase II trial of cetuximab plus irinotecan for oxaliplatin- and irinotecan-based chemotherapy-refractory patients with advanced and/or metastatic colorectal cancer: evaluation of efficacy and safety based on KRAS mutation status (T-CORE0801).Q54342085
Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer.Q54568648
Sessile serrated adenoma (SSA) vs. traditional serrated adenoma (TSA)Q80418165
Genome-wide identification of possible methylation markers chemosensitive to targeted regimens in colorectal cancersQ84785186
P433issue12
P921main subjectcolorectal cancerQ188874
biomarkerQ864574
DNA methylationQ874745
metastatic colon cancerQ108566365
P304page(s)1722-1729
P577publication date2015-10-01
P1433published inCancer ScienceQ326125
P1476titleDNA methylation status as a biomarker of anti-epidermal growth factor receptor treatment for metastatic colorectal cancer
P478volume106

Reverse relations

cites work (P2860)
Q37725589ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer.
Q97525750Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance
Q37321131Blood-based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance)
Q55124199Consensus molecular subtypes classification of colorectal cancer as a predictive factor for chemotherapeutic efficacy against metastatic colorectal cancer.
Q50607666CpG island methylator phenotype is associated with the efficacy of sequential oxaliplatin- and irinotecan-based chemotherapy and EGFR-related gene mutation in Japanese patients with metastatic colorectal cancer.
Q52536411DNA methylation as a marker of response in rheumatoid arthritis.
Q55342871Optimising the use of cetuximab in the continuum of care for patients with metastatic colorectal cancer.
Q38805790Potential biomarkers for anti-EGFR therapy in metastatic colorectal cancer

Search more.