review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1080/03602530600569919 |
P698 | PubMed publication ID | 16684653 |
P2093 | author name string | David E Williams | |
Sharon K Krueger | |||
Ronald N Hines | |||
Jonathan E Vandyke | |||
P2860 | cites work | The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein | Q22004271 |
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Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione | Q24293146 | ||
Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics | Q24539077 | ||
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Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans | Q28203039 | ||
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Stereoselective metabolism of (S)-(-)-nicotine in humans: formation of trans-(S)-(-)-nicotine N-1'-oxide | Q28250108 | ||
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Phenotypes of flavin-containing monooxygenase activity determined by ranitidine N-oxidation are positively correlated with genotypes of linked FM03 gene mutations in a Korean population | Q28374623 | ||
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Study on the organoleptic intensity scale for measuring oral malodor. | Q34285698 | ||
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An overview of the mechanism, substrate specificities, and structure of FMOs | Q34818980 | ||
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Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen. | Q40463031 | ||
CYP2D6-mediated catalysis of tamoxifen aromatic hydroxylation with an NIH shift: similar hydroxylation mechanism in chicken, rat and human liver microsomes | Q44353593 | ||
Evaluation of xenobiotic N- and S-oxidation by variant flavin-containing monooxygenase 1 (FMO1) enzymes | Q44771795 | ||
Tamoxifen and metabolite concentrations in serum and breast cancer tissue during three dose regimens in a randomized preoperative trial. | Q44836596 | ||
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Genetic polymorphisms of human flavin monooxygenase 3 in sulindac-mediated primary chemoprevention of familial adenomatous polyposis | Q45205080 | ||
Organ specificity of DNA adduct formation by tamoxifen and alpha-hydroxytamoxifen in the rat: implications for understanding the mechanism(s) of tamoxifen carcinogenicity and for human risk assessment | Q46520781 | ||
Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin | Q46575106 | ||
Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes. | Q53468349 | ||
A comparative study of tamoxifen metabolism in female rat, mouse and human liver microsomes. | Q53473144 | ||
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Microsomal oxidase. IV. Properties of a mixed-function amine oxidase isolated from pig liver microsomes | Q70378536 | ||
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Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3 | Q77425114 | ||
P433 | issue | 1-2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | tamoxifen | Q412178 |
P304 | page(s) | 139-147 | |
P577 | publication date | 2006-01-01 | |
P1433 | published in | Drug Metabolism Reviews | Q5308857 |
P1476 | title | The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines | |
P478 | volume | 38 |
Q92229907 | Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs |
Q45218281 | Development of a CD-MEKC method for investigating the metabolism of tamoxifen by flavin-containing monooxygenases and the inhibitory effects of methimazole, nicotine and DMXAA. |
Q51770720 | Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. |
Q45050255 | Differential gene expression in ERα-positive and ERα-negative breast cancer cells upon leptin stimulation |
Q37008890 | Flavin-containing monooxygenase 3 and human disease |
Q55359029 | In silico prediction of potential chemical reactions mediated by human enzymes. |
Q34038020 | Partial inhibition of estrogen-induced mammary carcinogenesis in rats by tamoxifen: balance between oxidant stress and estrogen responsiveness |
Q90525391 | Production of drug metabolites by human FMO3 in Escherichia coli |
Q46639348 | Role of the Red Ginseng in Defense against the Environmental Heat Stress in Sprague Dawley Rats. |
Q36140832 | SLC15A2 genomic variation is associated with the extraordinary response of sorafenib treatment: whole-genome analysis in patients with hepatocellular carcinoma |
Q37772507 | The potential of knockout mouse lines in defining the role of flavin-containing monooxygenases in drug metabolism |
Q36107130 | Tissue distribution of 4-hydroxy-N-desmethyltamoxifen and tamoxifen-N-oxide |
Q47155427 | Variations in plasma concentrations of tamoxifen metabolites and the effects of genetic polymorphisms on tamoxifen metabolism in Korean patients with breast cancer |
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