Toward a core nutraceutical program for cancer management

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Toward a core nutraceutical program for cancer management is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1177/1534735406288443
P698PubMed publication ID16685077

P50authorKeith I BlockQ94114016
P2093author name stringMark F McCarty
P2860cites workEffects of water-soluble Ganoderma lucidum polysaccharides on the immune functions of patients with advanced lung cancer.Q53268582
Thrombin receptor expression is upregulated in prostate cancer.Q53652220
Oral magnesium supplementation improves insulin sensitivity in non-diabetic subjects with insulin resistance. A double-blind placebo-controlled randomized trial.Q53891794
Nutritional supplementation of the leucine metabolite beta-hydroxy-beta-methylbutyrate (hmb) during resistance training.Q54037648
Immune receptors for polysaccharides from Ganoderma lucidum.Q54702908
An in vivo study of hepatic and splenic interleukin-1 beta mRNA expression following oral PSK or LEM administration.Q55109509
Diet and body mass index in 38 000 EPIC-Oxford meat-eaters, fish-eaters, vegetarians and vegansQ57421556
Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trialQ57943255
Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signallingQ24307907
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitorsQ24676378
Oxygen-regulated transcription factors and their role in pulmonary diseaseQ24791474
One year soy protein supplementation has positive effects on bone formation markers but not bone density in postmenopausal womenQ24800268
Prevention of Cancer Through Lifestyle ChangesQ24808755
IL-12 Production Induced by Agaricus blazei Fraction H (ABH) Involves Toll-like Receptor (TLR)Q24808841
Regulation of multiple insulin-like growth factor binding protein genes by 1alpha,25-dihydroxyvitamin D3.Q24816287
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinomaQ28166746
A prospective study of plasma C-peptide and colorectal cancer risk in menQ28168133
Aspirin inhibits in vitro maturation and in vivo immunostimulatory function of murine myeloid dendritic cellsQ28184794
Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in vitro invasion of tumor cellsQ28184976
Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cellsQ28192896
Suppression of lung metastasis by aspirin but not indomethacin in an in vivo model of chemically induced hepatocellular carcinomaQ28194117
Inhibition of human colon carcinoma development by lentinan from shiitake mushrooms (Lentinus edodes)Q28216802
Tissue factor and fibrin in tumor angiogenesisQ28251842
Daily ingestion of fermented milk containing Lactobacillus casei DN114001 improves innate-defense capacity in healthy middle-aged peopleQ28285488
Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humansQ28289663
Role of chromium in human health and in diabetesQ28289713
A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese dietQ28298898
Oral magnesium supplementation inhibits platelet-dependent thrombosis in patients with coronary artery diseaseQ28369787
Folate: a key to optimizing health and reducing disease risk in the elderlyQ28645810
Inhibition of NF-kappa B by sodium salicylate and aspirinQ29614708
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-betaQ29617188
Magnesium deficiency is associated with insulin resistance in obese children.Q30436679
Hypercalcaemia of malignancy and basic research on mechanisms responsible for osteolytic and osteoblastic metastasis to boneQ30438085
The profibrinolytic enzyme subtilisin NAT purified from Bacillus subtilis Cleaves and inactivates plasminogen activator inhibitor type 1.Q30666324
Effect of glutamine supplementation of the diet on tissue protein synthesis rate of glucocorticoid-treated ratsQ31881027
Polysaccharides from Agaricus blazei stimulate lymphocyte T-cell subsets in miceQ32065119
Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallateQ32159522
PTHrP gene expression in cancer: do all paths lead to Ets?Q33705984
The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancerQ33874156
Effect of oral eicosapentaenoic acid on weight loss in patients with pancreatic cancer.Q33909028
Proteolysis-inducing factor is expressed in tumours of patients with gastrointestinal cancers and correlates with weight lossQ33950842
Reversal of cancer-related wasting using oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamineQ33958795
Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trialQ33968290
Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial).Q33977885
An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: a North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effortQ33979114
Natural killer cell activity and quality of life were improved by consumption of a mushroom extract, Agaricus blazei Murill Kyowa, in gynecological cancer patients undergoing chemotherapyQ33980579
Mechanism of the attenuation of proteolysis-inducing factor stimulated protein degradation in muscle by beta-hydroxy-beta-methylbutyrateQ33983462
The relationship between a urinary cachectic factor and weight loss in advanced cancer patientsQ33984284
Attenuation of proteasome-induced proteolysis in skeletal muscle by {beta}-hydroxy-{beta}-methylbutyrate in cancer-induced muscle lossQ33984500
NF-kappaB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscleQ33985083
Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse modelQ33986996
Extrinsic-pathway activation in cancer with high factor VIIa and tissue factorQ34057583
Induction of muscle protein degradation by a tumour factorQ34065542
Nuclear factor-kappaB: the enemy withinQ35893620
Tumor-host interactionsQ35902161
Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathwaysQ35926915
Hypercoagulability in the metabolic syndrome.Q36076184
Molecular signaling pathways regulating muscle proteolysis during atrophyQ36089017
Parathyroid hormone-related protein in prostate cancerQ36098134
On the role of galectin-3 in cancer apoptosisQ36103556
The epidemiology of vitamin D and cancer incidence and mortality: a review (United States).Q36114755
Copper lowering therapy with tetrathiomolybdate as an antiangiogenic strategy in cancerQ36126566
Minireview: role of the growth hormone/insulin-like growth factor system in mammalian agingQ36141285
The insulin-like growth factor-I receptor as a target for cancer therapyQ36219706
Failure of vitamin E in clinical trials: is gamma-tocopherol the answer?Q36270921
Current insights into the role of transforming growth factor-beta in bone resorption.Q36283949
Multifocal angiostatic therapy: an updateQ36311166
I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone lossQ36402985
Season of diagnosis is a prognostic factor in Hodgkin's lymphoma: a possible role of sun-induced vitamin D.Q36615246
Protracted venous infusion 5-fluorouracil in combination with subcutaneous interleukin-2 and alpha-interferon in patients with metastatic renal cell cancer: a phase II studyQ36621976
Increased expression of the ubiquitin-proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB.Q36648384
Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapyQ36689936
Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancerQ36975194
Induction of tissue factor expression in human endothelial cells by CD40 ligand is mediated via activator protein 1, nuclear factor kappa B, and Egr-1.Q38289775
Transcriptional regulation of tissue factor expression in human endothelial cellsQ38295839
Transforming growth factor beta regulates parathyroid hormone-related protein expression in MDA-MB-231 breast cancer cells through a novel Smad/Ets synergismQ38296040
Induction of protein catabolism in myotubes by 15(S)-hydroxyeicosatetraenoic acid through increased expression of the ubiquitin-proteasome pathwayQ38304915
Involvement of Nuclear Factor-κB in the Inhibition of Interleukin-12 Production from Mouse Macrophages by Baicalein, a Flavonoid inScutellaria baicalensisQ38349534
Role of protein kinase C and NF-kappaB in proteolysis-inducing factor-induced proteasome expression in C(2)C(12) myotubesQ38799171
Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activationQ38802465
Topotecan blocks hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cellsQ40414489
Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma lucidum, in mice.Q40416233
Autocrine metabolism of vitamin D in normal and malignant breast tissueQ40427845
Inhibition of interleukin-12 production in mouse macrophages via decreased nuclear factor-kappaB DNA binding activity by myricetin, a naturally occurring flavonoidQ40434748
Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathwaysQ40495382
IKKbeta/NF-kappaB activation causes severe muscle wasting in miceQ40505119
Signalling pathways in the induction of proteasome expression by proteolysis-inducing factor in murine myotubesQ40510613
Curcumin (diferuloylmethane) inhibits receptor activator of NF-kappa B ligand-induced NF-kappa B activation in osteoclast precursors and suppresses osteoclastogenesisQ40558772
Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenograftsQ40568556
PTH-related protein enhances MCF-7 breast cancer cell adhesion, migration, and invasion via an intracrine pathwayQ40578212
Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implicationsQ40585883
The prostate 25-hydroxyvitamin D-1 alpha-hydroxylase is not influenced by parathyroid hormone and calcium: implications for prostate cancer chemoprevention by vitamin D.Q40598330
Antitumour activity of the silybin-phosphatidylcholine complex, IdB 1016, against human ovarian cancerQ40626611
Efficacy of Vitamin D compounds to modulate estrogen receptor negative breast cancer growth and invasion.Q40652893
Ets2 and protein kinase C epsilon are important regulators of parathyroid hormone-related protein expression in MCF-7 breast cancer cellsQ40665255
Parathyroid hormone-related protein enhances PC-3 prostate cancer cell growth via both autocrine/paracrine and intracrine pathwaysQ40745072
Chemopreventive effect of Lactobacillus rhamnosus on growth of a subcutaneously implanted bladder cancer cell line in the mouseQ40755997
Natural history of HLA expression during tumour development.Q40797268
Tumor cell adhesion to endothelial cells is increased by endotoxin via an upregulation of beta-1 integrin expressionQ40810258
Monomethyl selenium--specific inhibition of MMP-2 and VEGF expression: implications for angiogenic switch regulationQ40828475
Identification and immune regulation of 25-hydroxyvitamin D-1-alpha-hydroxylase in murine macrophagesQ40887948
Antiproliferative activity of flavonoids on several cancer cell linesQ40946396
The NF-kappaB binding site is essential for transcriptional activation of the IL-15 geneQ41040079
Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: role of the nuclear transcription factor NF-kappa B.Q41085611
Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by loss of the aminophospholipid translocaseQ41087163
The noncalcemic vitamin D analogues EB1089 and 22-oxacalcitriol interact with the vitamin D receptor and suppress parathyroid hormone-related peptide gene expressionQ41120912
Regulation of the tissue factor gene in human monocytic cells. Role of AP-1, NF-kappa B/Rel, and Sp1 proteins in uninduced and lipopolysaccharide-induced expressionQ41129739
Harry M. Vars Research Award. Glutamine enhances immunoregulation of tumor growthQ41433982
Point of view--a role for "nutritional insurance" supplementation in preventive medicineQ41633269
Pharmacological interference with tissue hypercatabolism in tumour-bearing ratsQ42142955
Hypoxia-associated induction of early growth response-1 gene expressionQ42472170
Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group.Q42528232
Development of an in-vitro model system to investigate the mechanism of muscle protein catabolism induced by proteolysis-inducing factorQ42559551
Inhibition of 15-lipoxygenases by flavonoids: structure-activity relations and mode of actionQ43486331
Enhancement of natural killer cytotoxicity delayed murine carcinogenesis by a probiotic microorganismQ43564045
Growth hormone together with glutamine-containing total parenteral nutrition maintains muscle glutamine levels and results in a less negative nitrogen balance after surgical traumaQ43594348
The effect of thiamine supplementation on tumour proliferation. A metabolic control analysis studyQ43698055
Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy.Q43718558
Glutamine supplementation in cancer patientsQ43723202
The association of diet and thrombotic risk factors in healthy male vegetarians and meat-eaters.Q43788296
Unexpected serious toxicity with chemotherapy and antiangiogenic combinations: time to take stock!Q43918759
Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosisQ43919085
Effect of palm oil carotene on breast cancer tumorigenicity in nude miceQ44066120
Increased tumor necrosis factor alpha (TNF-alpha) and natural killer cell (NK) function using an integrative approach in late stage cancersQ44083311
Eicosapentaenoic acid supplementation reduces tumor volume and attenuates cachexia in a rat model of progressive non-metastasizing malignancyQ44128613
Vitamin D receptor-dependent antitumour effects of 1,25-dihydroxyvitamin D3 and two synthetic analogues in three in vivo models of prostate cancerQ44136002
Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitusQ44205749
Observations on the doubling time of prostate cancer.The use of serial prostate-specific antigen in patients with untreated disease as a measure of increasing cancer volumeQ44226068
Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trialQ44381365
Prostaglandin E2 Suppresses NK Activity In Vivo and Promotes Postoperative Tumor Metastasis in RatsQ44431969
A wholly nutritional 'multifocal angiostatic therapy' for control of disseminated cancerQ44462149
Vitamin D2 analog 19-nor-1,25-dihydroxyvitamin D2: antitumor activity against leukemia, myeloma, and colon cancer cellsQ44482258
Prostate cancer cell type-specific regulation of the human PTHrP gene via a negative VDRE.Q44506068
Dietary n-3 fatty acids decrease osteoclastogenesis and loss of bone mass in ovariectomized miceQ44509153
Gold compounds inhibit adhesion of human cancer cells to vascular endothelial cellsQ44512775
Selenium and immune cell functions. II. Effect on lymphocyte-mediated cytotoxicityQ44519731
Effects of Lentinus edodes, Grifola frondosa and Pleurotus ostreatus administration on cancer outbreak, and activities of macrophages and lymphocytes in mice treated with a carcinogen, N-butyl-N-butanolnitrosoamineQ44529214
Weight loss reduces tissue factor in morbidly obese patientsQ44548928
Thrombin induces neoangiogenesis in the chick chorioallantoic membraneQ44604222
Effect of glutamine on the initiation and promotion phases of DMBA‐induced mammary tumor developmentQ44657684
Phase 1B study to improve immune responses in head and neck cancer patients using escalating doses of 25-hydroxyvitamin D3.Q44675420
Modified citrus pectin (MCP) increases the prostate-specific antigen doubling time in men with prostate cancer: a phase II pilot studyQ44685336
The association between magnesium intake and fasting insulin concentration in healthy middle-aged womenQ44699048
Plasma levels of tissue factor antigen in patients with non-insulin-dependent diabetes mellitusQ44789225
Vitamin D3 from sunlight may improve the prognosis of breast-, colon- and prostate cancer (Norway).Q44797217
Simvastatin treatment partially prevents ovariectomy-induced bone loss while increasing cortical bone formationQ44819483
Regulation of parathyroid hormone-related protein gene expression by epidermal growth factor-family ligands in primary human keratinocytesQ44836090
Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS).Q44895898
25-hydroxyvitamin D3-1alpha-hydroxylase expression in normal and malignant human colon.Q44945503
Sub-optimal taurine status may promote platelet hyperaggregability in vegetariansQ45003165
HMG-CoA reductase inhibitors and the risk of vertebral fractureQ45018992
Statin lipid-lowering drugs and bone mineral densityQ45073873
Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and proliferation by targeting phosphatidylinositol 3'-kinase activity.Q45134048
A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer.Q45158856
Dendritic cells might be one of key factors for eliciting antitumor effect by chemoimmunotherapy in vivoQ45183771
Magnesium may mediate the favorable impact of whole grains on insulin sensitivity by acting as a mild calcium antagonistQ45200412
Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistanceQ45205116
Solar radiation, vitamin D and survival rate of colon cancer in NorwayQ45263203
Pilot study: potential role of vitamin D (Cholecalciferol) in patients with PSA relapse after definitive therapyQ45304293
Nutritional treatment for acquired immunodeficiency virus-associated wasting using beta-hydroxy beta-methylbutyrate, glutamine, and arginine: a randomized, double-blind, placebo-controlled studyQ45742019
Growth inhibitory and antimetastatic effect of green tea polyphenols on metastasis-specific mouse mammary carcinoma 4T1 cells in vitro and in vivo systemsQ46365785
Sequential, randomized trial of a low-fat, high-fiber diet and soy supplementation: effects on circulating IGF-I and its binding proteins in premenopausal womenQ46413160
Cyclooxygenase inhibitors modulate NK activities that control metastatic diseaseQ46488570
Dietary treatment of rheumatoid cachexia with beta-hydroxy-beta-methylbutyrate, glutamine and arginine: a randomised controlled trialQ46492688
The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenograftsQ46652649
1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activationQ46665943
Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).Q47397491
Immuno-potentiating effects of the antler-shaped fruiting body of Ganoderma lucidum (Rokkaku-Reishi).Q47671495
A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitroQ47879899
Potentiation of cytotoxic activity in naïve and tumor-bearing mice by oral administration of hot-water extracts from Agaricus brazei fruiting bodiesQ48013976
ABC of palliative care. Anorexia, cachexia, and nutritionQ34065633
Thrombosis in cancer patientsQ34083025
Vitamin K and bone healthQ34099640
Meta-analyses of therapies for postmenopausal osteoporosis. VII. Meta-analysis of calcium supplementation for the prevention of postmenopausal osteoporosisQ34146697
Effects of a mushroom mycelium extract on the treatment of prostate cancerQ34154980
The insulin-like growth factor system and cancerQ34200058
Insulin-like growth factor-I in muscle metabolism and myotherapies.Q34329895
Modulation of natural killer cell activity by supplementation of fermented milk containing Lactobacillus casei in habitual smokers.Q34400266
Hypercalcemia of malignancyQ34437562
Intensive lifestyle changes may affect the progression of prostate cancerQ34442113
Platelet-derived growth factor receptors: a therapeutic target in solid tumorsQ34461490
Control of protein synthesis by amino acid availabilityQ34493700
Effect of omega 3 polyunsaturated fatty acid ingestion on bone metabolism and osteoporosisQ34589619
Role of growth hormone, insulin-like growth factor-I, and insulin-like growth factor binding proteins in the catabolic response to injury and infectionQ34601336
Folic acid and homocysteine in age-related diseaseQ34662356
The argument for increasing selenium intakeQ34754393
Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organsQ34768486
Insulin-like growth factor-1 inscribes a gene expression profile for angiogenic factors and cancer progression in breast epithelial cellsQ34928974
Low magnesium and atherosclerosis: an evidence-based link.Q35049639
HMG-CoA reductase inhibitors in osteoporosis: do they reduce the risk of fracture?Q35107704
Vitamin D in preventive medicine: are we ignoring the evidence?Q35117137
Protective role of n-3 lipids and soy protein in osteoporosisQ35150595
Pathogenesis of increased risk of thrombosis in cancer.Q35187967
Nutritional and clinical relevance of lutein in human healthQ35545380
Antiproliferative role of vitamin D and its analogs--a brief overviewQ35584913
Selective protein kinase C inhibitors and their applicationsQ35610642
Natural killer cells and cancerQ35622883
Insulin and cancerQ35624527
Galectin-3 and metastasisQ35646658
The anti-angiogenic basis of metronomic chemotherapyQ35788112
Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancerQ35791879
Signaling pathways responsible for cancer cell invasion as targets for cancer therapyQ35793957
Galectin-3 induces endothelial cell morphogenesis and angiogenesisQ35809815
Evidence for a link between IGF-I and cancer.Q35875689
P433issue2
P921main subjectnutraceuticalQ533025
P304page(s)150-171
P577publication date2006-06-01
P1433published inIntegrative Cancer TherapiesQ15708568
P1476titleToward a core nutraceutical program for cancer management
P478volume5

Reverse relations

cites work (P2860)
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Q37127379Influence of diet on metastasis and tumor dormancy.
Q24651188Modified citrus pectin anti-metastatic properties: one bullet, multiple targets
Q34171005Reduced cancer risk in vegetarians: an analysis of recent reports
Q33967052Type IIB procollagen NH(2)-propeptide induces death of tumor cells via interaction with integrins alpha(V)beta(3) and alpha(V)beta(5).

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