The B cell response in multiple sclerosis

scientific article published in April 2006

The B cell response in multiple sclerosis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1179/016164106X98099
P698PubMed publication ID16687047
P5875ResearchGate publication ID7094311

P2093author name stringDonald H Gilden
Gregory P Owens
Jeffrey L Bennett
Mark P Burgoon
P2860cites workBAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphomaQ24646563
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Comparison of immunoglobulin G heavy-chain sequences in MS and SSPE brains reveals an antigen-driven responseQ30854079
Restricted use of VH4 germline segments in an acute multiple sclerosis brainQ32107477
Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulationQ33784134
Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosisQ34098936
B cells and antibodies in CNS demyelinating diseaseQ34100103
Characterization of immune complexes in progressive rubella panencephalitisQ34283025
Oligoclonal bands and antibody responses in multiple sclerosisQ34609976
Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin.Q35168188
Three or more routes for leukocyte migration into the central nervous systemQ35183162
B cells in multiple sclerosisQ35650942
The CD4-Th1 model for multiple sclerosis: a critical [correction of crucial] re-appraisalQ35702792
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Regulation of plasma-cell developmentQ36058417
Temporal invariance and clonal uniformity of brain and cerebrospinal IgG, IgA, and IgM in multiple sclerosisQ36351504
Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reactionQ36368672
Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and bloodQ36602220
Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.Q37285430
Protective long-term antibody memory by antigen-driven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organsQ37290484
Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis.Q37385073
A reappraisal of the epidemiology of multiple sclerosis in Olmsted County, MinnesotaQ37786871
The T lymphocyte in experimental allergic encephalomyelitisQ37925549
HTLV-I-associated myelopathy: oligoclonal immunoglobulin G bands contain anti-HTLV-I p24 antibodyQ39033631
Immunoglobulin class and light chain type of oligoclonal bands in CSF in multiple sclerosis determined by agarose gel electrophoresis and immunofixationQ39692368
Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patientsQ40656580
Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosisQ41788436
Mumps Meningitis: Prolonged Pleocytosis and Occurrence of Mumps Virus-Specific Oligoclonal IgG in the Cerebrospinal FluidQ41873376
Oligoclonal immunoglobulins in cerebrospinal fluid during varicella zoster virus (VZV) vasculopathy are directed against VZVQ42606319
Accumulation of clonally related B lymphocytes in the cerebrospinal fluid of multiple sclerosis patientsQ42619341
Analysis of the intrathecal humoral immune response in Brown Norway (BN) rats, infected with the murine coronavirus JHM.Q43484023
Antibody-mediated CNS demyelination II. Focal spinal cord lesions induced by implantation of an IgM antisulfatide-secreting hybridomaQ44728931
An isoelectric focusing study in herpes simplex virus encephalitisQ44804340
Neurosyphilis: intrathecal synthesis of oligoclonal antibodies to Treponema pallidumQ44960784
Detection of CSF-specific oligoclonal antibodies to recombinant JC virus VP1 in patients with progressive multifocal leukoencephalopathy.Q45762642
An isoelectric focusing overlay study of the humoral immune response in Theiler's virus demyelinating diseaseQ45830882
Oligoclonal measles virus-specific IgG antibodies isolated from cerebrospinal fluids, brain extracts, and sera from patients with subacute sclerosing panencephalitis and multiple sclerosisQ45885704
B-lymphocyte and plasma cell clonal expansion in monosymptomatic optic neuritis cerebrospinal fluidQ47242758
Comparative analysis of the CD19+ and CD138+ cell antibody repertoires in the cerebrospinal fluid of patients with multiple sclerosisQ47309556
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.Q47357498
The immunogenesis of the multiple sclerosis plaqueQ47742417
Determinants of Human B Cell Migration Across Brain Endothelial CellsQ48328973
Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: a new viewQ48400195
Transfer of central nervous system autoantigens and presentation in secondary lymphoid organsQ48451211
Multiple sclerosis: in situ evidence for antibody- and complement-mediated demyelinationQ48489118
The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesionQ48646930
Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosisQ48949365
The immunoglobulin G heavy chain repertoire in multiple sclerosis plaques is distinct from the heavy chain repertoire in peripheral blood lymphocytesQ49065980
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
Single-cell repertoire analysis demonstrates that clonal expansion is a prominent feature of the B cell response in multiple sclerosis cerebrospinal fluid.Q54759503
Intrathecal IgM synthesis predicts the onset of new relapses and a worse disease course in MS.Q55036043
Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complementQ59099066
Anti-myelin antibodies do not allow earlier diagnosis of multiple sclerosisQ59273850
Unveiling the enigma of the CNS as a B-cell fostering environmentQ61657776
Patterns of oligodendroglia pathology in multiple sclerosisQ61709808
Cryptococcus neoformans-specific oligoclonal immunoglobulins in cerebrospinal fluid in cryptococcal meningitisQ66695381
Distribution of cerebrospinal fluid oligoclonal IgM bands in neurological diseases: a comparison between agarose electrophoresis and isoelectric focusingQ68034474
Multiple sclerosis: capping of surface immunoglobulin G on macrophages engaged in myelin breakdownQ70180407
Comparison of agar gel electrophoresis and isoelectric focusing in multiple sclerosis and subacute sclerosing panencephalitisQ72630861
Multiple Sclerosis: Distribution of T Cell Subsets Within Active Chronic LesionsQ72773066
Pathogenesis of multiple sclerosis: the eyes only see what the mind is prepared to comprehendQ79834864
Receptor revision and atypical mutational characteristics in clonally expanded B cells from the cerebrospinal fluid of recently diagnosed multiple sclerosis patientsQ81119751
P433issue3
P921main subjectmultiple sclerosisQ8277
P304page(s)236-244
P577publication date2006-04-01
P1433published inNeurological ResearchQ15765622
P1476titleThe B cell response in multiple sclerosis
P478volume28

Reverse relations

cites work (P2860)
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Q51890165[Atacicept: a new B lymphocyte-targeted therapy for multiple sclerosis].

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