Cleavage of anti-apoptotic Bcl-2 family members after TCR stimulation contributes to the decision between T cell activation and apoptosis

scientific article

Cleavage of anti-apoptotic Bcl-2 family members after TCR stimulation contributes to the decision between T cell activation and apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1201610
P932PMC publication ID3529753
P698PubMed publication ID23203923

P2093author name stringJin Wang
Min Chen
Alan D Guerrero
Robert L Welschhans
P2860cites workApoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or BakQ24296478
CD95's deadly mission in the immune systemQ28142072
Apoptosis by death factorQ28304002
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligandQ28513283
Caspases 3 and 7: key mediators of mitochondrial events of apoptosisQ28588439
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosisQ30080034
Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environmentQ33652471
The many roles of FAS receptor signaling in the immune systemQ34205697
Critical role for perforin and Fas-dependent killing of dendritic cells in the control of inflammationQ35651696
Modulation of cell death by Bcl-XL through caspase interactionQ35739439
NRAS mutation causes a human autoimmune lymphoproliferative syndrome.Q35829141
Role of Bim and other Bcl-2 family members in autoimmune and degenerative diseasesQ36361205
Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunityQ36501636
Life and death in peripheral T cellsQ36858872
Critical role for BIM in T cell receptor restimulation-induced deathQ36862396
Delineation of the caspase-9 signaling cascadeQ40075487
Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarizationQ40213057
Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosisQ40245914
Autoimmune disease. a problem of defective apoptosisQ40393793
Fas and Fas ligand: lpr and gld mutationsQ40398275
Caspase-9 and effector caspases have sequential and distinct effects on mitochondriaQ40399437
Lentiviral transduction of human dendritic cells.Q40588784
Differential requirement for caspase 9 in apoptotic pathways in vivo.Q41015558
Conversion of Bcl-2 to a Bax-like death effector by caspasesQ41073693
The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene clusterQ41471760
Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contractionQ43493690
Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosisQ43539775
Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members.Q52582383
gld/gld mice are unable to express a functional ligand for Fas.Q55063278
T cell growth cytokines cause the superinduction of molecules mediating antigen-induced T lymphocyte deathQ74463460
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamiliesQ79370601
Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunityQ80703822
Dendritic cell apoptosis in the maintenance of immune toleranceQ82647177
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
P304page(s)168-173
P577publication date2012-11-30
P1433published inJournal of ImmunologyQ3521441
P1476titleCleavage of anti-apoptotic Bcl-2 family members after TCR stimulation contributes to the decision between T cell activation and apoptosis
P478volume190

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cites work (P2860)
Q38980598Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells
Q57492030Control of Immunoregulatory Molecules by miRNAs in T Cell Activation
Q94452467JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction
Q36052919Loss of marginal zone B-cells in SHIVSF162P4 challenged rhesus macaques despite control of viremia to low or undetectable levels in chronic infection
Q41007184Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor-dependent apoptosis.
Q35882987Protective effect of bone marrow mesenchymal stem cells on PC12 cells apoptosis mediated by TAG1
Q50278432The Antitumor Effects of Vaccine-Activated CD8+ T Cells Associate with Weak TCR Signaling and Induction of Stem-Like Memory T Cells
Q36216308The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses.

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