Orexin modulates brown adipose tissue thermogenesis

scientific article published on August 2012

Orexin modulates brown adipose tissue thermogenesis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1515/BMC-2011-0066
P932PMC publication ID3535439
P698PubMed publication ID23293681

P50authorDomenico TuponeQ42373684
P2093author name stringShaun F Morrison
Christopher J Madden
P2860cites workElevated body temperature during sleep in orexin knockout mice.Q42055479
2010 Carl Ludwig Distinguished Lectureship of the APS Neural Control and Autonomic Regulation Section: Central neural pathways for thermoregulatory cold defenseQ42736843
Excitatory effects of hypocretin-1 (orexin-A) in the trigeminal motor nucleus are reversed by NMDA antagonismQ44336714
Neuronal activity of orexin and non-orexin waking-active neurons during wake-sleep states in the mouseQ45783558
Heating and eating: brown adipose tissue thermogenesis precedes food ingestion as part of the ultradian basic rest-activity cycle in ratsQ48027219
Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsyQ48473912
Orexin inputs to caudal raphé neurons involved in thermal, cardiovascular, and gastrointestinal regulationQ48560642
Increased body mass index (BMI) in male narcoleptic patients, but not in HLA-DR2-positive healthy male volunteersQ48614095
Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activitiesQ48680835
Low cerebrospinal fluid hypocretin (Orexin) and altered energy homeostasis in human narcolepsyQ48683622
Increased prevalence of obesity in narcoleptic patients and relativesQ48691377
Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesityQ48691942
Circadian distribution of motor activity and immobility in narcolepsy: assessment with continuous motor activity monitoringQ48820872
Increased body-mass index in patients with narcolepsy.Q54565465
Hypocretin (orexin) deficiency in human narcolepsy.Q55033530
Spontaneous food choice in narcolepsyQ71125158
Hypocretin deficiency in narcoleptic humans is associated with abdominal obesityQ73938524
Serotonin potentiates sympathetic responses evoked by spinal NMDAQ80264241
Orexin neurons are indispensable for stress-induced thermogenesis in miceQ84970915
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behaviorQ24315738
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activityQ24317782
Identification and importance of brown adipose tissue in adult humansQ24632425
The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 geneQ28142783
Cold-activated brown adipose tissue in healthy menQ29547382
High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposityQ29615454
Narcolepsy in orexin knockout mice: molecular genetics of sleep regulationQ29615680
Neurons containing hypocretin (orexin) project to multiple neuronal systemsQ29619641
GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue.Q31913424
Fos expression in orexin neurons varies with behavioral state.Q32062017
RVLM and raphe differentially regulate sympathetic outflows to splanchnic and brown adipose tissueQ33178096
Endogenous activation of spinal 5-hydroxytryptamine (5-HT) receptors contributes to the thermoregulatory activation of brown adipose tissueQ33523667
Brown adipose tissue in morbidly obese subjectsQ33842257
Orexin is required for brown adipose tissue development, differentiation, and functionQ34222436
Behavioral state instability in orexin knock-out mice.Q34333442
Central neural pathways for thermoregulation.Q34636440
An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesisQ35574603
Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibitionQ35693126
Central control of brown adipose tissue thermogenesisQ35796368
Brown adipose tissue sympathetic nerve activity is potentiated by activation of 5-hydroxytryptamine (5-HT)1A/5-HT7 receptors in the rat spinal cordQ36569699
Central control of thermogenesis in mammalsQ36812556
Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivityQ37071459
Brown adipose tissue thermogenesis heats brain and body as part of the brain-coordinated ultradian basic rest-activity cycle.Q37399620
Body mass index-independent metabolic alterations in narcolepsy with cataplexy.Q37402576
Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuitsQ40017136
Identification of sympathetic premotor neurons in medullary raphe regions mediating fever and other thermoregulatory functions.Q40532178
Paradoxical [correction of parodoxical] effect of orexin A: hypophagia induced by hyperthermiaQ40567450
P433issue4
P921main subjectthermogenesisQ965695
P304page(s)381-386
P577publication date2012-08-01
P1433published inBiomolecular conceptsQ26853930
P1476titleOrexin modulates brown adipose tissue thermogenesis
P478volume3

Reverse relations

cites work (P2860)
Q37208047A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance.
Q47207949CNS β3-adrenergic receptor activation regulates feeding behavior, white fat browning, and body weight
Q35618665Central nervous system regulation of brown adipose tissue
Q64067855Combined Effect of Fatty Diet and Cognitive Decline on Brain Metabolism, Food Intake, Body Weight, and Counteraction by Intranasal Insulin Therapy in 3×Tg Mice
Q52662325Contribution of Dynorphin and Orexin Neuropeptide Systems to the Motivational Effects of Alcohol.
Q35238259Early expression of hypocretin/orexin in the chick embryo brain
Q34404186Leptin receptor neurons in the dorsomedial hypothalamus are key regulators of energy expenditure and body weight, but not food intake
Q92537514Orexins/Hypocretins: Key Regulators of Energy Homeostasis
Q48101291Role of the Suprachiasmatic and Arcuate Nuclei in Diurnal Temperature Regulation in the Rat.
Q39026723Roles for Orexin/Hypocretin in the Control of Energy Balance and Metabolism
Q57817996Sleep-Wake Cycling and Energy Conservation: Role of Hypocretin and the Lateral Hypothalamus in Dynamic State-Dependent Resource Optimization
Q26865368The brain and brown fat
Q52316130The hypocretin/orexin system as a target for excessive motivation in alcohol use disorders.
Q38258673The role of orexin in motivated behaviours

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