Brown adipose tissue sympathetic nerve activity is potentiated by activation of 5-hydroxytryptamine (5-HT)1A/5-HT7 receptors in the rat spinal cord

scientific article published on 5 November 2007

Brown adipose tissue sympathetic nerve activity is potentiated by activation of 5-hydroxytryptamine (5-HT)1A/5-HT7 receptors in the rat spinal cord is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEUROPHARM.2007.10.019
P8608Fatcat IDrelease_cbsqsj3zzjcgjndjybt6xb2nam
P932PMC publication ID2322875
P698PubMed publication ID18082230
P5875ResearchGate publication ID5766874

P2093author name stringS F Morrison
C J Madden
P2860cites workAdditive effect of A-->G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesityQ71902459
Autoradiographic localization of 5-hydroxytryptamine1A, 5-hydroxytryptamine1B and 5-hydroxytryptamine1C/2 binding sites in the rat spinal cordQ72878525
Serotonin potentiates sympathetic responses evoked by spinal NMDAQ80264241
Effects of the 5-HT7 receptor antagonist SB-269970 on rat hormonal and temperature responses to the 5-HT1A/7 receptor agonist 8-OH-DPATQ83945291
A review of central 5-HT receptors and their functionQ28142963
[(3)H]-SB-269970--A selective antagonist radioligand for 5-HT(7) receptorsQ28344255
Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult ratQ28565096
5-HT5A receptor localization in the rat spinal cord suggests a role in nociception and control of pelvic floor musculatureQ28584178
Brown adipose tissue: function and physiological significanceQ29547448
Hypoxic activation of arterial chemoreceptors inhibits sympathetic outflow to brown adipose tissue in ratsQ31170930
Activation of 5-HT1A receptors in raphe pallidus inhibits leptin-evoked increases in brown adipose tissue thermogenesisQ33197094
Thermoregulation: some concepts have changed. Functional architecture of the thermoregulatory systemQ33999825
The human uncoupling protein-1 gene (UCP1): present status and perspectives in obesity researchQ34139112
The distribution of brown adipose tissue in the humanQ34228011
Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agentsQ34262666
Activation of 5-HT1A receptors in rostral medullary raphé inhibits cutaneous vasoconstriction elicited by cold exposure in rabbitsQ34490962
Thermoregulatory responses to serotonin (5-HT) receptor stimulation in the rat. Evidence for opposing roles of 5-HT2 and 5-HT1A receptorsQ34562816
5-Hydroxytryptamine receptorsQ35270959
Central pathways controlling brown adipose tissue thermogenesisQ35689268
Subcutaneous fat in normal and diseased states: 2. Anatomy and physiology of white and brown adipose tissueQ36274260
Immunocytochemical studies of the 5-HT(1A) receptor in ventral medullaryneurons that project to the intermediolateral cell column and contain serotonin or tyrosine hydroxylase immunoreactivityQ36848575
Neurotransmitters in temperature controlQ39441046
Changes in body temperature after administration of adrenergic and serotonergic agents and related drugs including antidepressants: II.Q39479345
5-HT2A-mu opioid receptor mechanisms in the hypothalamus mediate interleukin-1beta fever in ratsQ40508946
The influence of 5-hydroxytryptamine agonists and antagonists on identified sympathetic preganglionic neurones in the rat, in vivoQ41983990
5-Hydroxytryptamine 1A receptors inhibit cold-induced sympathetically mediated cutaneous vasoconstriction in rabbits.Q44543846
8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodentsQ44806863
Spinal 5-HT2A receptors regulate cutaneous sympathetic vasomotor outflow in rabbits and rats; relevance for cutaneous vasoconstriction elicited by MDMA (3,4-methylenedioxymethamphetamine, "Ecstasy") and its reversal by clozapineQ44948786
Cloned human 5-HT1A receptor pharmacology determined using agonist binding and measurement of cAMP accumulationQ45105452
Thermogenesis in brown adipose tissue: increase by 5-HT2A receptor activation and decrease by 5-HT1A receptor activation in conscious ratsQ46808943
The cellular localization of 5-HT2A receptors in the spinal cord and spinal ganglia of the adult rat.Q47962801
Selective labelling of 5-HT7 receptor recognition sites in rat brain using [3H]5-carboxamidotryptamineQ48307092
Anatomical substrates for the central control of sympathetic outflow to interscapular adipose tissue during cold exposure.Q48336978
Autoradiographic mapping of 5-HT1, 5-HT1A, 5-HT1B and 5-HT2 receptors in the rat spinal cordQ48719545
Origins of serotonergic projections to the spinal cord in rat: an immunocytochemical-retrograde transport studyQ49135237
Serotoninergic and nonserotoninergic neurons in the medullary raphe system have axon collateral projections to autonomic and somatic cell groups in the medulla and spinal cord.Q50766814
Uncoupling protein gene: quantification of expression levels in adipose tissues of obese and non-obese humans.Q50923377
The vertebral level of origin of spinal nerves in the ratQ67582687
Contribution of BAT and skeletal muscle to thermogenesis induced by ephedrine in manQ69944611
The thermoregulatory effects of noradrenaline, serotonin and carbachol injected into the rat spinal subarachnoid spaceQ71865622
P433issue3
P1104number of pages10
P304page(s)487-496
P577publication date2007-11-05
P1433published inNeuropharmacologyQ15332439
P1476titleBrown adipose tissue sympathetic nerve activity is potentiated by activation of 5-hydroxytryptamine (5-HT)1A/5-HT7 receptors in the rat spinal cord
P478volume54

Reverse relations

cites work (P2860)
Q39278472An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesis
Q37564409Autonomic regulation of brown adipose tissue thermogenesis in health and disease: potential clinical applications for altering BAT thermogenesis
Q33841082Bradycardia in serotonin-deficient Pet-1-/- mice: influence of respiratory dysfunction and hyperthermia over the first 2 postnatal weeks
Q35796368Central control of brown adipose tissue thermogenesis
Q36812556Central control of thermogenesis in mammals
Q35618665Central nervous system regulation of brown adipose tissue
Q34636440Central neural pathways for thermoregulation.
Q33523667Endogenous activation of spinal 5-hydroxytryptamine (5-HT) receptors contributes to the thermoregulatory activation of brown adipose tissue
Q33994940Inhibition of brown adipose tissue thermogenesis by neurons in the ventrolateral medulla and in the nucleus tractus solitarius
Q41471294Monoaminergic modulation of spinal viscero-sympathetic function in the neonatal mouse thoracic spinal cord
Q37641816Multiple thermoregulatory effectors with independent central controls.
Q30434312Neurochemistry of bulbospinal presympathetic neurons of the medulla oblongata
Q36503608Orexin modulates brown adipose tissue thermogenesis
Q35025821Potentiation of 5-methoxy-N,N-dimethyltryptamine-induced hyperthermia by harmaline and the involvement of activation of 5-HT1A and 5-HT2A receptors
Q36316193Role of the Oxytocin Receptor Expressed in the Rostral Medullary Raphe in Thermoregulation During Cold Conditions
Q38431920Serotonin and Serotonin Transporters in the Adrenal Medulla: A Potential Hub for Modulation of the Sympathetic Stress Response
Q90625353Systemic serotonin inhibits brown adipose tissue sympathetic nerve activity via a GABA input to the dorsomedial hypothalamus, not via 5HT1A receptor activation in raphe pallidus
Q41572299Telemetry monitoring for non-invasive assessment of changes in core temperature after spinal drug administration in freely moving rats
Q92342404The capacity for oestrogen to influence obesity through brown adipose tissue thermogenesis in animal models: A systematic review and meta-analysis
Q46778118The inhibition of neurons in the central nervous pathways for thermoregulatory cold defense induces a suspended animation state in the rat.

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