Association of alpha-, beta-, and gamma-Synuclein with diffuse lewy body disease

scientific article published on August 2010

Association of alpha-, beta-, and gamma-Synuclein with diffuse lewy body disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1001/ARCHNEUROL.2010.177
P932PMC publication ID4727539
P698PubMed publication ID20697047
P5875ResearchGate publication ID45583492

P50authorCarles Vilariño-GüellQ24283836
Zbigniew K WszolekQ64754704
Alex RajputQ64855014
Owen A. RossQ67167640
Barbara Jasinska-MygaQ83920460
Tanis J FermanQ91521563
Alexandra I Soto-OrtolazaQ114336709
Jennifer M KachergusQ114430207
Dennis W. DicksonQ30504740
Matthew J. FarrerQ37380292
P2093author name stringKenya Nishioka
Sarah J Lincoln
Christopher A Robinson
Christian Wider
P2860cites workEvolutionarily conserved elements in vertebrate, insect, worm, and yeast genomesQ24534193
alpha-Synuclein promoter confers susceptibility to Parkinson's disease.Q54699461
-Synuclein and Parkinson disease susceptibilityQ57983273
Lrrk2 pathogenic substitutions in Parkinson's diseaseQ57983291
Evaluation of the γ-synuclein gene in German Parkinson's disease patientsQ60689238
No pathogenic mutations in the beta-synuclein gene in Parkinson's disease.Q64858749
Diffuse Lewy body diseaseQ64917946
Lewy body disease with and without dementia: a clinicopathological study of 35 casesQ68029418
Beta-synuclein inhibits formation of alpha-synuclein protofibrils: a possible therapeutic strategy against Parkinson's diseaseQ73196542
Validation of the neuropathologic criteria of the third consortium for dementia with Lewy bodies for prospectively diagnosed casesQ24653609
Beta-synuclein gene alterations in dementia with Lewy bodiesQ24684579
Mutation in the alpha-synuclein gene identified in families with Parkinson's diseaseQ27860459
Alpha-synuclein in Lewy bodiesQ27860680
Developmental expression and biochemical characterization of Emu family membersQ28504556
Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of dataQ28943545
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementiaQ29547174
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's diseaseQ29547175
Diagnosis and management of dementia with Lewy bodies: third report of the DLB ConsortiumQ29614409
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disordersQ29614754
Widespread alterations of alpha-synuclein in multiple system atrophyQ30444927
Gamma-synucleinopathy: neurodegeneration associated with overexpression of the mouse proteinQ30487162
Multiple regions of alpha-synuclein are associated with Parkinson's diseaseQ31155710
Improved accuracy of clinical diagnosis of Lewy body Parkinson's diseaseQ33183045
Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain BankQ33445409
Absence of mutation in the beta- and gamma-synuclein genes in familial autosomal dominant Parkinson's disease.Q33853344
A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each otherQ33909759
Alzheimer disease with amygdala Lewy bodies: a distinct form of alpha-synucleinopathyQ33997481
beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factorQ34099593
Beta-synuclein modulates alpha-synuclein neurotoxicity by reducing alpha-synuclein protein expressionQ34564479
Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's diseaseQ34565111
Beta-synuclein gene variants and Parkinson's disease: a preliminary case-control studyQ35994987
Genetics of Parkinson disease: paradigm shifts and future prospects.Q36423921
SNCA variants are associated with increased risk for multiple system atrophyQ36460907
Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synucleinQ36677512
Diffuse Lewy body disease in JapanQ37941288
Phylemon: a suite of web tools for molecular evolution, phylogenetics and phylogenomicsQ42148193
Diffuse type of Lewy body disease: progressive dementia with abundant cortical Lewy bodies and senile changes of varying degree--a new disease?Q42445413
Reply to: SNCA variants are associated with increased risk of multiple system atrophyQ43067213
The Sydney multicenter study of Parkinson's disease: the inevitability of dementia at 20 yearsQ44801054
Mutations in the gene encoding human persyn are not associated with amyotrophic lateral sclerosis or familial Parkinson's diseaseQ47918224
P433issue8
P921main subjectSynucleinQ24767155
P304page(s)970-975
P577publication date2010-08-01
P1433published inArchives of NeurologyQ15766672
P1476titleAssociation of alpha-, beta-, and gamma-Synuclein with diffuse lewy body disease
P478volume67

Reverse relations

cites work (P2860)
Q60960028A Meta-Analysis of α-Synuclein Multiplication in Familial Parkinsonism
Q38121773Advances in the genetics of Parkinson disease
Q39117185An exome study of Parkinson's disease in Sardinia, a Mediterranean genetic isolate
Q42427291Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients
Q64242757Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity
Q35094391Bridging molecular genetics and biomarkers in lewy body and related disorders
Q43063576CD4⁺ but not CD8⁺ T cells revert the impaired emotional behavior of immunocompromised RAG-1-deficient mice
Q36618103Can we clinically diagnose dementia with Lewy bodies yet?
Q48366824Common genetic etiology between "multiple sclerosis-like" single-gene disorders and familial multiple sclerosis
Q35186314Comparative analysis of human tissue interactomes reveals factors leading to tissue-specific manifestation of hereditary diseases
Q38501488Dementia With Lew Body: Impacts of Surgery
Q34389030Evaluation of the role of SNCA variants in survival without neurological disease
Q58740519Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course
Q38594414Genetic susceptibility variants in parkinsonism
Q38310765Genetics and underlying pathology of dementia
Q41954719Mutations in PRKN and SNCA Genes Important for the Progress of Parkinson's Disease
Q42062219New α- and γ-synuclein immunopathological lesions in human brain
Q64236121Next Generation Sequencing Analysis in Early Onset Dementia Patients
Q36321837Possible alterations in β-Synuclein, the non-amyloidogenic homologue of α-Synuclein, during progression of sporadic α-synucleinopathies
Q34323256Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis
Q27694711The Synaptic Function of α-Synuclein
Q38139561The function of α-synuclein
Q34074501The genetic contributions of SNCA and LRRK2 genes to Lewy Body pathology in Alzheimer's disease
Q34450376UPDATE ON DEMENTIA WITH LEWY BODIES.
Q44085138Zebrafish brain proteomics reveals central proteins involved in neurodegeneration
Q39841127α-synuclein genetic variability: A biomarker for dementia in Parkinson disease

Search more.