Alternative splicing: new insights from global analyses

scientific article published on July 2006

Alternative splicing: new insights from global analyses is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/J.CELL.2006.06.023
P698PubMed publication ID16839875
P5875ResearchGate publication ID6945558

P50authorBenjamin J. BlencoweQ63212972
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectalternative mRNA splicing, via spliceosomeQ21114084
P304page(s)37-47
P577publication date2006-07-01
P1433published inCellQ655814
P1476titleAlternative splicing: new insights from global analyses
P478volume126

Reverse relations

cites work (P2860)
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Q37517945Alternative splicing modulates stem cell differentiation
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Q34077168An alternative splicing network links cell-cycle control to apoptosis
Q39588800An exon-centric perspective
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Q39798256An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons
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Q37240124Analysis of protein isoforms: can we do it better?
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Q39825334Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.
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Q35914084BIPASS: BioInformatics Pipeline Alternative Splicing Services
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Q38798600Beyond quantification: in situ analysis of transcriptome and pre-mRNA alternative splicing at the nanoscale
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Q28727771CD28 costimulation regulates genome-wide effects on alternative splicing
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Q36245773CUG-BP1 regulates RyR1 ASI alternative splicing in skeletal muscle atrophy
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Q38513923Characterization and comparison of intron structure and alternative splicing between Medicago truncatula, Populus trichocarpa, Arabidopsis and rice
Q42621345Characterization of a novel isoform of the human ORMDL3 gene
Q35159933Characterization of lacrimal proline-rich protein 4 (PRR4) in human tear proteome
Q28249240Characterization of splice variants of the genes encoding human mitochondrial HMG-CoA lyase and HMG-CoA synthase, the main enzymes of the ketogenesis pathway
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Q34769399Characterization of transcriptional complexity during longissimus muscle development in bovines using high-throughput sequencing
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Q35698947Computational and experimental approaches double the number of known introns in the pathogenic yeast Candida albicans
Q33708655Connections between alternative transcription and alternative splicing in mammals
Q34874403Conservation and functional influence of alternative splicing in wood formation of Populus and Eucalyptus
Q33426349Conserved alternative splicing and expression patterns of arthropod N-cadherin.
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Q90705843Construction of a model to predict the prognosis of patients with cholangiocarcinoma using alternative splicing events
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Q34575267Copy number variations in alternative splicing gene networks impact lifespan
Q33561283Core promoter structure and genomic context reflect histone 3 lysine 9 acetylation patterns
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Q27486159Cross-kingdom patterns of alternative splicing and splice recognition
Q33293249Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1
Q51475656Cystinosin-LKG rescues cystine accumulation and decreases apoptosis rate in cystinotic proximal tubular epithelial cells.
Q33604490Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells
Q39334970DENN/MADD/IG20 alternative splicing changes and cell death in Alzheimer's disease
Q37159006DNA sequencing methods in human genetics and disease research
Q31151038De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function
Q35970681Deciphering the plant splicing code: experimental and computational approaches for predicting alternative splicing and splicing regulatory elements
Q34022324Deciphering the splicing code
Q33543635Deep RNA sequencing at single base-pair resolution reveals high complexity of the rice transcriptome
Q29547470Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
Q36898112Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2.
Q54240155Detection of protein-RNA crosslinks by NanoLC-ESI-MS/MS using precursor ion scanning and multiple reaction monitoring (MRM) experiments.
Q34865319Determinants of Nam8-dependent splicing of meiotic pre-mRNAs
Q36768147Developing global insight into RNA regulation
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Q39831315Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins
Q28728163Developmental splicing deregulation in leukodystrophies related to EIF2B mutations
Q37810374Developments in RNA splicing and disease
Q33809160Differential alternative splicing of human transglutaminase 4 in benign prostate hyperplasia and prostate cancer
Q30638597Differential increases of specific FMR1 mRNA isoforms in premutation carriers
Q28591390Differential isoform expression and interaction with the P32 regulatory protein controls the subcellular localization of the splicing factor U2AF26
Q33419869Directing experimental biology: a case study in mitochondrial biogenesis
Q33285873Discovery and analysis of evolutionarily conserved intronic splicing regulatory elements
Q37072907Discovery and mass spectrometric analysis of novel splice-junction peptides using RNA-Seq
Q42710079Distinct patterns of expression and evolution of intronless and intron-containing mammalian genes
Q34964532Divergence of exonic splicing elements after gene duplication and the impact on gene structures.
Q21092736Diverse RNA-binding proteins interact with functionally related sets of RNAs, suggesting an extensive regulatory system
Q38295424Diverse roles of hnRNP L in mammalian mRNA processing: a combined microarray and RNAi analysis
Q33374539Diverse splicing patterns of exonized Alu elements in human tissues
Q33348728Dual coding in alternative reading frames correlates with intrinsic protein disorder.
Q34637786Dual role of G-runs and hnRNP F in the regulation of a mutation-activated pseudoexon in the fibrinogen gamma-chain transcript
Q36002580Dual-specificity splice sites function alternatively as 5' and 3' splice sites
Q40508997Dunning rat prostate adenocarcinomas and alternative splicing reporters: powerful tools to study epithelial plasticity in prostate tumors in vivo
Q36500142Dynamic expression pattern of neuro-oncological ventral antigen 1 (Nova1) in the rat brain after focal cerebral ischemia/reperfusion insults
Q41984492Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition
Q34779368Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution
Q38612755Dynamic usage of alternative splicing exons during mouse retina development
Q37341247Effect of exonic splicing regulation on synonymous codon usage in alternatively spliced exons of Dscam
Q43291305Effects of splice sites on the intron retention in histamine H3 receptors from rats and mice
Q38039409Emerging Roles of Alternative Pre-mRNA Splicing Regulation in Neuronal Development and Function
Q36631204Emerging roles for Sam68 in adipogenesis and neuronal development
Q33533332Endothelial cell processing and alternatively spliced transcripts of factor VIII: potential implications for coagulation cascades and pulmonary hypertension
Q36978479Enzyme isoforms may increase phenotypic robustness
Q37600658Evaluation of Bax and Bak gene mutations and expression in breast cancer
Q33791162Evolution at protein ends: major contribution of alternative transcription initiation and termination to the transcriptome and proteome diversity in mammals
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Q51469786Evolution of gene structural complexity: an alternative-splicing-based model accounts for intron-containing retrogenes.
Q60952340Evolution of maternal and zygotic mRNA complements in the early Drosophila embryo
Q36173074Exclusion of RPGRIP1 ins44 from primary causal association with early-onset cone-rod dystrophy in dogs.
Q33340712Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences
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Q33358687Exon expression arrays as a tool to identify new cancer genes
Q36643166Exon expression profiling reveals stimulus-mediated exon use in neural cells
Q34027831Exon-level microarray analyses identify alternative splicing programs in breast cancer
Q33758515Expanding roles for metabolite-sensing regulatory RNAs
Q55649364Exploration of potential roles of a new LOXL2 splicing variant using network knowledge in esophageal squamous cell carcinoma.
Q35381106Exploring the secrets of long noncoding RNAs
Q54345724Expression analysis of osteopontin mRNA splice variants in prostate cancer and benign prostatic hyperplasia.
Q35197073Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis
Q60046875Extensive Alternative Splicing of KIR Transcripts
Q33275964Eye development under the control of SRp55/B52-mediated alternative splicing of eyeless
Q34292752FOX-2 dependent splicing of ataxin-2 transcript is affected by ataxin-1 overexpression
Q24321295Fas-activated serine/threonine kinase (FAST K) synergizes with TIA-1/TIAR proteins to regulate Fas alternative splicing
Q24314362Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing
Q36642426Finding exonic islands in a sea of non-coding sequence: splicing related constraints on protein composition and evolution are common in intron-rich genomes
Q36970521Frequent S100A4 Expression with Unique Splicing Pattern in Gastric Cancers: A Hypomethylation Event Paralleled with E-cadherin Reduction and Wnt Activation
Q38061013From single splicing events to thousands: the ambiguous step forward in splicing research
Q46174244Functional characterization of the human-specific (type II) form of kallikrein 8, a gene involved in learning and memory
Q50753405Functional characterization of two alternatively spliced transcripts of tomato ABSCISIC ACID INSENSITIVE3 (ABI3) gene.
Q34632366Functional consequences of developmentally regulated alternative splicing
Q36672416Functional coordination of alternative splicing in the mammalian central nervous system
Q33331043Functional importance of different patterns of correlation between adjacent cassette exons in human and mouse
Q24337706Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation
Q33552998Functional selection and systematic analysis of intronic splicing elements identify active sequence motifs and associated splicing factors
Q41957401Fungal alternative splicing is associated with multicellular complexity and virulence: a genome-wide multi-species study
Q34098699Garbled messages and corrupted translations
Q39436207Gene Array Analyzer: alternative usage of gene arrays to study alternative splicing events
Q36459361Gene and genon concept: coding versus regulation. A conceptual and information-theoretic analysis of genetic storage and expression in the light of modern molecular biology
Q36978765Genes and proteins: dogmas in decline
Q40100749Genetic approaches to studying adenosine-to-inosine RNA editing.
Q26858897Genetic variation of pre-mRNA alternative splicing in human populations
Q28650280Genetics of gene expression in CNS
Q34657673Genome and proteome annotation: organization, interpretation and integration
Q37173731Genome-wide analysis of alternative pre-mRNA splicing and RNA-binding specificities of the Drosophila hnRNP A/B family members
Q38456544Genome-wide analysis of alternative splicing events in Hordeum vulgare: Highlighting retention of intron-based splicing and its possible function through network analysis.
Q34548324Genome-wide analysis of alternative splicing in Caenorhabditis elegans
Q28471962Genome-wide analysis of immune activation in human T and B cells reveals distinct classes of alternatively spliced genes
Q33881344Genome-wide evidence for selection acting on single amino acid repeats
Q33829781Genome-wide functional analysis of human 5' untranslated region introns
Q80565664Genome-wide identification of C2H2 zinc-finger gene family in rice and their phylogeny and expression analysis
Q33560271Genome-wide mapping of alternative splicing in Arabidopsis thaliana
Q33481246Genome-wide prediction of cis-acting RNA elements regulating tissue-specific pre-mRNA alternative splicing
Q33911844Genome-wide survey of Alternative Splicing in Sorghum Bicolor.
Q34249488Genomic HEXploring allows landscaping of novel potential splicing regulatory elements.
Q38061014Genomic analysis reveals novel connections between alternative splicing and circadian regulatory networks.
Q34631249Glial cell line-derived neurotrophic factor and neurturin inhibit neurite outgrowth and activate RhoA through GFR alpha 2b, an alternatively spliced isoform of GFR alpha 2.
Q40230210Global Gene Expression Profiling and Alternative Splicing Events during the Chondrogenic Differentiation of Human Cartilage Endplate-Derived Stem Cells
Q33333974Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays
Q24669968Global analysis of alternative splicing differences between humans and chimpanzees
Q35697465Global analysis of alternative splicing during T-cell activation
Q37205767Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells
Q36400692Global analysis of mRNA splicing
Q39678654Global analysis reveals SRp20- and SRp75-specific mRNPs in cycling and neural cells
Q46912463Global dissection of alternative splicing in paleopolyploid soybean
Q58605653Global dissection of alternative splicing uncovers transcriptional diversity in tissues and associates with the flavonoid pathway in tea plant (Camellia sinensis)
Q30497879Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer
Q50526762Global profiling of the gene expression and alternative splicing events during hypoxia-regulated chondrogenic differentiation in human cartilage endplate-derived stem cells.
Q24648963HITS-CLIP yields genome-wide insights into brain alternative RNA processing
Q42713273Heart failure-associated changes in RNA splicing of sarcomere genes
Q37406026Herpesvirus protein ICP27 switches PML isoform by altering mRNA splicing
Q38962228High-quality reference transcript datasets hold the key to transcript-specific RNA-sequencing analysis in plants
Q33420817High-throughput proteomics detection of novel splice isoforms in human platelets
Q33396813Highly diversified molecular evolution of downstream transcription start sites in rice and Arabidopsis
Q33705782Highly sensitive and multiplexed quantification of mRNA splice variants by the direct ligation of DNA probes at the exon junction and universal PCR amplification.
Q34630542Host cell transcriptome profile during wild-type and attenuated dengue virus infection
Q38265600How mRNA is misspliced in acute myelogenous leukemia (AML)?
Q35202794Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner
Q26746005Human Pituitary Adenoma Proteomics: New Progresses and Perspectives
Q36511718Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms
Q34621484Human transcriptome array for high-throughput clinical studies.
Q30857408IUTA: a tool for effectively detecting differential isoform usage from RNA-Seq data.
Q57737736Identification and characterization of a novel RPGR isoform in human retina
Q24337104Identification and characterization of new long chain acyl-CoA dehydrogenases
Q34779359Identification of MBNL1 and MBNL3 domains required for splicing activation and repression
Q83231535Identification of RBPMS as a mammalian smooth muscle master splicing regulator via proximity of its gene with super-enhancers
Q44948970Identification of a functional splice variant of 14-3-3E1 in rainbow trout
Q35575049Identification of a novel FRMD7 splice variant and functional analysis of two FRMD7 transcripts during human NT2 cell differentiation.
Q28537999Identification of a novel function of CX-4945 as a splicing regulator
Q39547082Identification of a novel protein isoform derived from cancer-related splicing variants using combined analysis of transcriptome and proteome
Q45909768Identification of androgen receptor variants in testis from humans and other vertebrates.
Q54643277Identification of exonic cis-elements regulating the alternative splicing of scleroderma-associated lysyl hydroxylase 2 mRNA.
Q33883077Identification, characterization, and utilization of single copy genes in 29 angiosperm genomes
Q33379609Implication of the F-Box Protein FBXL21 in circadian pacemaker function in mammals
Q37052723Improved identification of conserved cassette exons using Bayesian networks.
Q33291706Improved identification of enriched peptide RNA cross-links from ribonucleoprotein particles (RNPs) by mass spectrometry
Q37851045InTRONs in biotech
Q42022590Incomplete splicing of neutrophil-specific genes affects neutrophil development in a zebrafish model of poikiloderma with neutropenia
Q33361108Integrating expression data with domain interaction networks
Q42183268Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation
Q37420342Integrative transcriptome sequencing identifies trans-splicing events with important roles in human embryonic stem cell pluripotency.
Q35651203Intragenic alternative splicing coordination is essential for Caenorhabditis elegans slo-1 gene function
Q30366529Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene.
Q46260864Intron retention enhances gene regulatory complexity in vertebrates
Q35422927Intronic deletions of tva receptor gene decrease the susceptibility to infection by avian sarcoma and leukosis virus subgroup A.
Q39277603Intronic splicing enhancers, cognate splicing factors and context-dependent regulation rules
Q38909797Involvement of endocytosis and alternative splicing in the formation of the pathological process in the early stages of Parkinson's disease.
Q24651932Involvement of the nuclear cap-binding protein complex in alternative splicing in Arabidopsis thaliana
Q90390500Isoform-specific promotion of breast cancer tumorigenicity by TBX3 involves induction of angiogenesis
Q92391632Knockdown of spliceosome U2AF1 significantly inhibits the development of human erythroid cells
Q37690728LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies
Q57578017Language as ergonomic perfection
Q33319324Ligand-induced sequestering of branchpoint sequence allows conditional control of splicing
Q39031312Light Regulation of Alternative Pre-mRNA Splicing in Plants.
Q92832169LncRNA RP11-670E13.6, interacted with hnRNPH, delays cellular senescence by sponging microRNA-663a in UVB damaged dermal fibroblasts
Q37982678Long Noncoding RNAs: Insights from Biological Features and Functions to Diseases.
Q30301152Long non-coding RNAs as emerging regulators of differentiation, development, and disease
Q36406311Long-range RNA pairings contribute to mutually exclusive splicing
Q37232928Lymphocytes from P2X7-deficient mice exhibit enhanced P2X7 responses.
Q39970502MADS: a new and improved method for analysis of differential alternative splicing by exon-tiling microarrays
Q45729152Maize rough endosperm3 encodes an RNA splicing factor required for endosperm cell differentiation and has a nonautonomous effect on embryo development
Q37986326Making alternative splicing decisions during epithelial-to-mesenchymal transition (EMT).
Q38181600Measuring midkine: the utility of midkine as a biomarker in cancer and other diseases
Q35179872Mechanism of alternative splicing and its regulation
Q34467642Mechanisms and Regulation of Alternative Pre-mRNA Splicing
Q29615084Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
Q34670427Memory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLL
Q33767865MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development
Q30423199Mitogen-activated protein kinase phosphorylation of splicing factor 45 (SPF45) regulates SPF45 alternative splicing site utilization, proliferation, and cell adhesion
Q38357932Model-based probe set optimization for high-performance microarrays
Q42053969Modulating alternative splicing by cotranscriptional cleavage of nascent intronic RNA.
Q42787889Modulation of alternative splicing contributes to cancer development: focusing on p53 isoforms, p53β and p53γ.
Q59039798Molecular biology: RNA in control
Q53365994Molecular cloning, expression and subcellular distribution of an alternative splice variant of the porcine Sirt2 gene.
Q37157940Molecular determinants and evolutionary dynamics of wobble splicing
Q37865814More than a splicing code: integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation.
Q36223818Mucosal Expression of T Cell Gene Variants Is Associated with Differential Resistance to Teladorsagia circumcincta
Q39958784Multiple and specific mRNA processing targets for the major human hnRNP proteins
Q39293799Multiple isoforms of the translation initiation factor eIF4GII are generated via use of alternative promoters, splice sites and a non-canonical initiation codon
Q28732385Myocardial alternative RNA splicing and gene expression profiling in early stage hypoplastic left heart syndrome
Q38310537NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
Q40626048Nanog RNA-binding proteins YBX1 and ILF3 affect pluripotency of embryonic stem cells
Q34807839Networking in a global world: establishing functional connections between neural splicing regulators and their target transcripts
Q33328657Non-random retention of protein-coding overlapping genes in Metazoa
Q39862884Novel P2 promoter-derived HNF4alpha isoforms with different N-terminus generated by alternate exon insertion
Q37340064Novel fatty acid desaturase 3 (FADS3) transcripts generated by alternative splicing.
Q38531585Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal
Q50782119Novel transcripts and alternatively spliced genes are associated with early development in bovine embryos.
Q38301627Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB.
Q36878412OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds.
Q94562745ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms
Q38041981On the physiological significance of alternative splicing events in higher plants
Q38215322One gene, many neuropsychiatric disorders: lessons from Mendelian diseases.
Q39852005Oxidative stress-induced alternative splicing of transformer 2beta (SFRS10) and CD44 pre-mRNAs in gastric epithelial cells
Q35446814P transposable elements in Drosophila and other eukaryotic organisms
Q46047549PRPF31 alternative splicing and expression in human retina
Q55082864Physiological and Pathological Function of Serine/Arginine-Rich Splicing Factor 4 and Related Diseases.
Q91048607Physiological and druggable skipping of immunoglobulin variable exons in plasma cells
Q42566449Pin1 regulates parathyroid hormone mRNA stability
Q34498722Placenta-specific novel splice variants of Rho GDP dissociation inhibitor β are highly expressed in cancerous cells
Q38341668Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB.
Q36481243Position-dependent splicing activation and repression by SR and hnRNP proteins rely on common mechanisms.
Q38331266Post-transcriptional regulation of long noncoding RNAs in cancer
Q26853608Posttranscriptional gene regulation by long noncoding RNA
Q24646484Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol
Q26799301Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process
Q37868141Pre-mRNA splicing: where and when in the nucleus
Q33519499Predicting functional alternative splicing by measuring RNA selection pressure from multigenome alignments
Q38344582Predicting in vivo binding sites of RNA-binding proteins using mRNA secondary structure
Q33947267Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence homology
Q39740593Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments
Q33267346Probe selection and expression index computation of Affymetrix Exon Arrays
Q43067703Probe-level estimation improves the detection of differential splicing in Affymetrix exon array studies
Q26746120Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right end
Q58714868Profiles of alternative splicing in colorectal cancer and their clinical significance: A study based on large-scale sequencing data
Q91574624Prognostic index of aberrant mRNA splicing profiling acts as a predictive indicator for hepatocellular carcinoma based on TCGA SpliceSeq data
Q34042438Proteomic analysis reveals CACN-1 is a component of the spliceosome in Caenorhabditis elegans
Q33310420Proteomic study of the effects of complex environmental stresses in the livers of goldfish (Carassius auratus) that inhabit Gaobeidian Lake in Beijing, China.
Q30577352QUANTIFYING ALTERNATIVE SPLICING FROM PAIRED-END RNA-SEQUENCING DATA
Q34147077RBPDB: a database of RNA-binding specificities
Q38462589RNA sequencing provides insights into the toxicogenomic response of ZF4 cells to methyl methanesulfonate
Q35667587RNA splicing control: yet another gene regulatory role for long nuclear noncoding RNAs
Q37882854RNA splicing: disease and therapy
Q35619173RNA-Seq Uncovers SNPs and Alternative Splicing Events in Asian Lotus (Nelumbo nucifera).
Q34993977RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation
Q38198537RNA-binding proteins in neurological diseases.
Q42257010RNA-seq analysis of the C. briggsae transcriptome
Q28538998RNABindRPlus: a predictor that combines machine learning and sequence homology-based methods to improve the reliability of predicted RNA-binding residues in proteins
Q42916557Rapid generation of splicing reporters with pSpliceExpress
Q36151037Rapid, transcript-specific changes in splicing in response to environmental stress
Q39608589Rapid-response splicing reporter screens identify differential regulators of constitutive and alternative splicing.
Q35001141Re-capping the message
Q35018262Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation
Q37568412Regulation of Dscam exon 17 alternative splicing by steric hindrance in combination with RNA secondary structures
Q40091384Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways.
Q34820236Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference
Q34035543Regulation of alternative splicing by histone modifications
Q26999239Regulation of alternative splicing by local histone modifications: potential roles for RNA-guided mechanisms
Q38324240Regulation of alternative splicing by the circadian clock and food related cues
Q37383857Regulation of apoptosis and caspase-8 expression in neuroblastoma cells by isoforms of the IG20 gene
Q35822883Regulation of chemoresistance via alternative messenger RNA splicing
Q33371977Regulation of expression of two LY-6 family genes by intron retention and transcription induced chimerism
Q34330648Regulation of major histocompatibility complex class II gene expression, genetic variation and disease
Q37417141Regulation of mammalian pre-mRNA splicing
Q36748147Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay
Q41960596Regulation of neuron-specific alternative splicing of neurofibromatosis type 1 pre-mRNA.
Q90862545Regulation of zebrafish dorsoventral patterning by phase separation of RNA-binding protein Rbm14
Q41904897Repression of prespliceosome complex formation at two distinct steps by Fox-1/Fox-2 proteins
Q55043342Retained introns increase putative microRNA targets within 3' UTRs of human mRNA.
Q36877029Review: Alternative Splicing (AS) of Genes As An Approach for Generating Protein Complexity.
Q44324983Rewiring the dynamic interactome
Q37733017Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer.
Q38027974Role of splice variants in the metastatic progression of prostate cancer
Q35442986Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis
Q38772987Roles for RNA-binding proteins in development and disease
Q64107191Ryūtō: network-flow based transcriptome reconstruction
Q33656516SAW: a method to identify splicing events from RNA-Seq data based on splicing fingerprints
Q39115667SR Proteins: Binders, Regulators, and Connectors of RNA.
Q42115041SRRM4-dependent neuron-specific alternative splicing of protrudin transcripts regulates neurite outgrowth.
Q37208362SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart
Q36411169STAR family RNA-binding protein ASD-2 regulates developmental switching of mutually exclusive alternative splicing in vivo
Q24655267Sam68 regulates a set of alternatively spliced exons during neurogenesis
Q92276539Search for Novel Diagnostic Biomarkers of Prostate Inflammation-Related Disorders: Role of Transglutaminase Isoforms as Potential Candidates
Q35185573Secreted β3-integrin enhances natural killer cell activity against acute myeloid leukemia cells
Q47253622Serine/arginine rich splicing factor 2 expression and clinic pathological features indicating a prognostic factor in human hepatocellular carcinoma patients
Q37102591Sex-specific splicing in Drosophila: widespread occurrence, tissue specificity and evolutionary conservation
Q40625890Short linear motif acquisition, exon formation and alternative splicing determine a pathway to diversity for NCoR-family co-repressors.
Q33313872Signal-regulated Pre-mRNA occupancy by the general splicing factor U2AF.
Q92151753Single-Molecule Long-Read Sequencing Reveals the Diversity of Full-Length Transcripts in Leaves of Gnetum (Gnetales)
Q34667742Sodium channel point mutations associated with pyrethroid resistance in Chinese strains of Culex pipiens quinquefasciatus (Diptera: Culicidae).
Q29614572Spatio-temporal transcriptome of the human brain
Q35288257Specific correction of a splice defect in brain by nutritional supplementation.
Q37580763Specific regulation of low-abundance transcript variants encoding human Acyl-CoA binding protein (ACBP) isoforms
Q24669785Specific use of start codons and cellular localization of splice variants of human phosphodiesterase 9A gene
Q42270395Splice-mediated motif switching regulates disabled-1 phosphorylation and SH2 domain interactions
Q30791696SpliceVista, a tool for splice variant identification and visualization in shotgun proteomics data
Q99207600Spliced genes in muscle from Nelore Cattle and their association with carcass and meat quality
Q33534511SplicerAV: a tool for mining microarray expression data for changes in RNA processing
Q34318040SplicerEX: a tool for the automated detection and classification of mRNA changes from conventional and splice-sensitive microarray expression data
Q33871191Splicing factor and exon profiling across human tissues
Q55647209Splicing heterogeneity: separating signal from noise.
Q34582131Splicing in disease: disruption of the splicing code and the decoding machinery
Q35450183Splicing programs and cancer
Q50098862Splicing regulation by long noncoding RNAs.
Q24642620Splicing regulation: from a parts list of regulatory elements to an integrated splicing code
Q33552181Sporadic ALS has compartment-specific aberrant exon splicing and altered cell-matrix adhesion biology
Q34887390Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation
Q37022241Starvation actively inhibits splicing of glucose-6-phosphate dehydrogenase mRNA via a bifunctional ESE/ESS element bound by hnRNP K.
Q31108900Statistical modeling of isoform splicing dynamics from RNA-seq time series data
Q59357572Strand-Specific Dual RNA Sequencing of Bronchial Epithelial Cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions
Q34463372StringTie enables improved reconstruction of a transcriptome from RNA-seq reads
Q37452098Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation
Q30157105Structural diversity and differential expression of novel human intersectin 1 isoforms
Q33821535Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
Q36685861Synthetic RNA circuits
Q34223399Synthetic antibodies as tools to probe RNA-binding protein function
Q30835106Systematic analysis of alternative first exons in plant genomes
Q35212538Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators
Q90510554Systematic profiling of alternative splicing events and splicing factors in left- and right-sided colon cancer
Q36875501Systems perspectives on mRNA processing
Q41822867T-DNA insertion mutants reveal complex expression patterns of the aldehyde dehydrogenase 3H1 locus in Arabidopsis thaliana
Q39451094TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP.
Q55128284Targeting Splicing in Prostate Cancer.
Q38677249The Antisense Transcriptome and the Human Brain.
Q99711645The Crosstalk Between Epigenetic Mechanisms and Alternative RNA Processing Regulation
Q60534351The Evolution of Alternative Splicing in the Pax Family: The View from the Basal Chordate Amphioxus
Q41788378The Fox-1 family and SUP-12 coordinately regulate tissue-specific alternative splicing in vivo
Q47221632The Importance of ncRNAs as Epigenetic Mechanisms in Phenotypic Variation and Organic Evolution
Q24297656The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation
Q26777046The RNA Splicing Response to DNA Damage
Q36228723The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes.
Q28660089The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana
Q38885465The Working Modules of Long Noncoding RNAs in Cancer Cells
Q34135204The adaptive significance of unproductive alternative splicing in primates.
Q27321847The alternative splicing factor Nova2 regulates vascular development and lumen formation
Q48165841The alternative splicing of EAM8 contributes to early flowering and short-season adaptation in a landrace barley from the Qinghai-Tibetan Plateau
Q38763642The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators
Q33943786The asthma candidate gene NPSR1 mediates isoform specific downstream signalling
Q39924925The beta-catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression
Q38352748The cap binding complex influences H2B ubiquitination by facilitating splicing of the SUS1 pre-mRNA
Q39625449The characterization of two novel IRF-3 transcripts starting from intron 2 of the wild type of IRF-3.
Q36937324The chemokine network. II. On how polymorphisms and alternative splicing increase the number of molecular species and configure intricate patterns of disease susceptibility
Q37461082The coded functions of noncoding RNAs for gene regulation
Q47169888The comparison of alternative splicing among the multiple tissues in cucumber
Q47593150The contribution of alternative splicing to genetic risk for psychiatric disorders.
Q38239897The decalog of long non-coding RNA involvement in cancer diagnosis and monitoring.
Q34616355The differential transcription network between embryo and endosperm in the early developing maize seed
Q33661198The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events
Q28729039The evolution of Dscam genes across the arthropods
Q45812591The fitness cost of mis-splicing is the main determinant of alternative splicing patterns
Q37172305The gene regulatory logic of transcription factor evolution
Q28728363The human transcriptome: an unfinished story
Q35902056The impact of alternative splicing in vivo: mouse models show the way.
Q37327730The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction
Q36163483The induction of serine/threonine protein phosphorylations by a PDGFR/TrkA chimera in stably transfected PC12 cells
Q47152826The landscape of human mutually exclusive splicing.
Q46316816The long noncoding RNA Malat1: Its physiological and pathophysiological functions
Q39933660The low information content of Neurospora splicing signals: implications for RNA splicing and intron origin.
Q33351073The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
Q24676713The novel neuronal ceroid lipofuscinosis gene MFSD8 encodes a putative lysosomal transporter
Q58787070The prognostic significance of global aberrant alternative splicing in patients with myelodysplastic syndrome
Q37821623The regulation of parathyroid hormone secretion and synthesis
Q33303373The reverse in-gel kinase assay to profile physiological kinase substrates
Q38597347The role of Amh signaling in teleost fish--Multiple functions not restricted to the gonads
Q35996973The role of isoforms in the evolution of cryptic coloration in Peromyscus mice
Q42177302The shape-shifting quasispecies of RNA: one sequence, many functional folds
Q37359270The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts
Q38057608The spliceosome as a target of novel antitumour drugs
Q37335031The spliceosome as target for anticancer treatment
Q34097169The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration.
Q28510582The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function
Q33747803The structural complexity of the human BORIS gene in gametogenesis and cancer
Q41861173The terminator "Non-sense mediate mRNA decay": Its role in the termination of intron containing a premature termination codon.
Q34699824The tissue-specific RNA binding protein T-STAR controls regional splicing patterns of neurexin pre-mRNAs in the brain
Q33678966Tissue-specific and ubiquitous expression patterns from alternative promoters of human genes
Q33446942Tissue-specific expression of dentin sialophosphoprotein (DSPP) and its polymorphisms in mouse tissues
Q38288973Tissue-specific splicing factor gene expression signatures
Q56889970Toward a systems level view of the ECM and related proteins: a framework for the systematic definition and analysis of biological systems
Q33571089Towards reliable isoform quantification using RNA-SEQ data
Q66905238Toxoplasma gondii ROP17 inhibits the innate immune response of HEK293T cells to promote its survival
Q36706911Trans-regulation of the expression of the transcription factor MtHAP2-1 by a uORF controls root nodule development.
Q37349453TransComb: genome-guided transcriptome assembly via combing junctions in splicing graphs
Q33422097Transcription and splicing regulation in human umbilical vein endothelial cells under hypoxic stress conditions by exon array
Q39295049Transcriptional profiles underlying vulnerability and resilience in rats exposed to an acute unavoidable stress
Q89420917Transcriptome analysis of alternative splicing in peanut (Arachis hypogaea L.).
Q42705161Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation
Q52670066Transcriptome and alternative splicing analysis of nucleus pulposus cells in response to high oxygen tension: Involvement of high oxygen tension in the pathogenesis of intervertebral disc degeneration.
Q34041693Transcriptome instability as a molecular pan-cancer characteristic of carcinomas
Q34027064Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival
Q35553239Transcriptome profiling and sequencing of differentiated human hematopoietic stem cells reveal lineage-specific expression and alternative splicing of genes
Q35128057Transcriptome sequencing and analysis of the entomopathogenic fungus Hirsutella sinensis isolated from Ophiocordyceps sinensis
Q33610951Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types
Q93010182Transcriptomic analysis of early B-cell development in the chicken embryo
Q33552994Unconstrained mining of transcript data reveals increased alternative splicing complexity in the human transcriptome.
Q33283913Unfolding the mystery of alternative splicing through a unique method of in vivo selection
Q24321236Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5
Q27024947Using protein-binding microarrays to study transcription factor specificity: homologs, isoforms and complexes
Q36169650Variable exon usage of differentially-expressed genes associated with resistance of sheep to Teladorsagia circumcincta
Q49393183Variant snRNPs: New players within the spliceosome system.
Q43135720Variety is the splice of life
Q34128497What would you do if you could sequence everything?
Q34413222Whole transcriptome analyses of six thoroughbred horses before and after exercise using RNA-Seq
Q36940515Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
Q36587200Widespread splicing changes in human brain development and aging
Q39040344cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.
Q38142712hnRNP A1: the Swiss army knife of gene expression
Q33737589iCLIP predicts the dual splicing effects of TIA-RNA interactions.
Q44950735p53 is activated in response to disruption of the pre-mRNA splicing machinery.
Q38271411p600/UBR4 in the central nervous system

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