Biosynthetic route towards saxitoxin and shunt pathway

scientific article published on 4 February 2016

Biosynthetic route towards saxitoxin and shunt pathway is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1044864613
P356DOI10.1038/SREP20340
P932PMC publication ID4740887
P698PubMed publication ID26842222
P5875ResearchGate publication ID293010332

P50authorShigeki TsuchiyaQ87113679
P2093author name stringKazuo Nagasawa
Mari Yotsu-Yamashita
Keiichi Konoki
Yasukatsu Oshima
Yuko Cho
P2860cites workA stereospecific total synthesis of dl-saxitoxinQ56484259
A reinvestigation of saxitoxin production and sxtA in the ‘non-toxic’ Alexandrium tamarense Group V cladeQ58386542
Total Synthesis of (−)-DecarbamoyloxysaxitoxinQ59441659
THE FRESHWATER CYANOBACTERIUM PLANKTOTHRIX SP. FP1: MOLECULAR IDENTIFICATION AND DETECTION OF PARALYTIC SHELLFISH POISONING TOXINSQ60305279
Actions of saxitoxin on peripheral neuromuscular systemsQ72639717
A synthetic route to the saxitoxin skeleton: synthesis of decarbamoyl α-saxitoxinol, an analogue of saxitoxin produced by the cyanobacterium Lyngbya wolleiQ84396505
Terpendole E and its derivative inhibit STLC- and GSK-1-resistant Eg5Q87477101
Synthesis and identification of proposed biosynthetic intermediates of saxitoxin in the cyanobacterium Anabaena circinalis (TA04) and the dinoflagellate Alexandrium tamarense (Axat-2)Q87649831
The γ-aminobutyric acid shunt contributes to closing the tricarboxylic acid cycle in Synechocystis sp. PCC 6803Q88205917
Discovery of nuclear-encoded genes for the neurotoxin saxitoxin in dinoflagellatesQ21135371
Biosynthetic intermediate analysis and functional homology reveal a saxitoxin gene cluster in cyanobacteriaQ24647171
Evolution and distribution of saxitoxin biosynthesis in dinoflagellatesQ28681124
The globally distributed genus Alexandrium: multifaceted roles in marine ecosystems and impacts on human healthQ28732311
Biosynthesis of saxitoxin analogs: the unexpected pathwayQ29029289
Origin of saxitoxin biosynthetic genes in cyanobacteriaQ33457157
Paralytic shellfish poisoning toxin-producing cyanobacterium Aphanizomenon gracile in northeast GermanyQ33649146
The first evidence of paralytic shellfish toxins in the fresh water cyanobacterium Cylindrospermopsis raciborskii, isolated from Brazil.Q33868713
Voltage-gated sodium channels at 60: structure, function and pathophysiologyQ34265707
Detection of Saxitoxin-Producing Cyanobacteria and Anabaena circinalis in Environmental Water Blooms by Quantitative PCRQ34334788
Preparation of calibration standards of N1-H paralytic shellfish toxin analogues by large-scale culture of cyanobacterium Anabaena circinalis (TA04).Q34874426
Evidence for paralytic shellfish poisons in the freshwater cyanobacterium Lyngbya wollei (Farlow ex Gomont) comb. nov.Q35203836
sxtA-based quantitative molecular assay to identify saxitoxin-producing harmful algal blooms in marine watersQ35271581
A stereocontrolled synthesis of (+)-saxitoxin.Q35872306
Saxitoxin, a toxic marine natural product that targets a multitude of receptorsQ36435221
Evolutionary acquisition and loss of saxitoxin biosynthesis in dinoflagellates: the second "core" gene, sxtGQ36757380
An overview on the marine neurotoxin, saxitoxin: genetics, molecular targets, methods of detection and ecological functionsQ36994197
Cyanobacterial toxins: biosynthetic routes and evolutionary rootsQ38050848
Saxitoxin.Q38207566
Synthesis of a tricyclic bisguanidine compound structurally related to saxitoxin and its identification in paralytic shellfish toxin-producing microorganisms.Q38887310
Evolution of saxitoxin synthesis in cyanobacteria and dinoflagellatesQ42018455
A synthesis of (+)-saxitoxinQ46103027
Comparative proteomics reveals that a saxitoxin-producing and a nontoxic strain of Anabaena circinalis are two different ecotypes.Q46941867
Extraordinary conservation, gene loss, and positive selection in the evolution of an ancient neurotoxinQ47343948
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)20340
P577publication date2016-02-04
P1433published inScientific ReportsQ2261792
P1476titleBiosynthetic route towards saxitoxin and shunt pathway
P478volume6

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cites work (P2860)
Q47870149A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens.
Q92236294Biocatalytic synthesis of α-amino ketones
Q49488740Chemistry of a Unique Polyketide-like Synthase
Q39097793Cyanotoxins: producing organisms, occurrence, toxicity, mechanism of action and human health toxicological risk evaluation
Q90133633Identification of a Novel Saxitoxin Analogue, 12β-Deoxygonyautoxin 3, in the Cyanobacterium, Anabaena circinalis (TA04)
Q64065126Metabolomic study of saxitoxin analogues and biosynthetic intermediates in dinoflagellates using N-labelled sodium nitrate as a nitrogen source
Q48330538Synthesis and Identification of Key Biosynthetic Intermediates for the Formation of the Tricyclic Skeleton of Saxitoxin.
Q51175669The chemistry and biology of guanidine natural products.

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