Metabolomic study of saxitoxin analogues and biosynthetic intermediates in dinoflagellates using N-labelled sodium nitrate as a nitrogen source

Metabolomic study of saxitoxin analogues and biosynthetic intermediates in dinoflagellates using N-labelled sodium nitrate as a nitrogen source is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-019-39708-Y
P932PMC publication ID6401167
P698PubMed publication ID30837523

P2093author name stringKazuhiko Koike
Hiroshi Oikawa
Mari Yotsu-Yamashita
Keiichi Konoki
Yasukatsu Oshima
Yuko Cho
Takuo Omura
Shigeki Tsuchiya
P2860cites workiTRAQ-Based Quantitative Proteomic Analysis of a Toxigenic Dinoflagellate Alexandrium catenella and Its Non-toxigenic Mutant Exposed to a Cell Cycle Inhibitor Colchicine.Q52718410
Isotopic Combinatomer Analysis Provides in Vivo Evidence of the Direct Epimerization of Monoglucosyl Diacylglycerol in Cyanobacteria.Q54785775
OCEAN CLIMATE CHANGE, PHYTOPLANKTON COMMUNITY RESPONSES, AND HARMFUL ALGAL BLOOMS: A FORMIDABLE PREDICTIVE CHALLENGEQ56060267
Reflections on the ballast water dispersal—harmful algal bloom paradigmQ56777392
BIOCHEMICAL CHARACTERIZATION OF PARALYTIC SHELLFISH TOXIN BIOSYNTHESIS IN VITROQ60305060
The distribution and impacts of harmful algal bloom species in eastern boundary upwelling systemsQ60507618
Optimization of hydrophilic interaction liquid chromatography/mass spectrometry and development of solid-phase extraction for the determination of paralytic shellfish poisoning toxinsQ83315875
Synthesis and identification of proposed biosynthetic intermediates of saxitoxin in the cyanobacterium Anabaena circinalis (TA04) and the dinoflagellate Alexandrium tamarense (Axat-2)Q87649831
Dynamics of paralytic shellfish toxins and their metabolites during timecourse exposure of scallops Chlamys farreri and mussels Mytilus galloprovincialis to Alexandrium pacificumQ88738015
Discovery of nuclear-encoded genes for the neurotoxin saxitoxin in dinoflagellatesQ21135371
Neurotoxic alkaloids: saxitoxin and its analogsQ24632724
Biosynthetic intermediate analysis and functional homology reveal a saxitoxin gene cluster in cyanobacteriaQ24647171
The globally distributed genus Alexandrium: multifaceted roles in marine ecosystems and impacts on human healthQ28732311
Studies of marine planktonic diatoms. I. Cyclotella nana Hustedt, and Detonula confervacea (cleve) GranQ29617545
The toxic dinoflagellate Karenia brevis encodes novel type I-like polyketide synthases containing discrete catalytic domains.Q30369352
Tetrodotoxin, saxitoxin and their significance in the study of excitation phenomenaQ34231277
Microalgal metabolitesQ35165281
Biosynthetic route towards saxitoxin and shunt pathwayQ36542620
Synthesis of a tricyclic bisguanidine compound structurally related to saxitoxin and its identification in paralytic shellfish toxin-producing microorganisms.Q38887310
Column switching combined with hydrophilic interaction chromatography-tandem mass spectrometry for the analysis of saxitoxin analogues, and their biosynthetic intermediates in dinoflagellates.Q39211575
Evolution of saxitoxin synthesis in cyanobacteria and dinoflagellatesQ42018455
Quantitative determination of paralytic shellfish toxins in cultured toxic algae by LC-MS/MS.Q45839128
Identification of a saxitoxin biosynthesis gene with a history of frequent horizontal gene transfersQ46319923
Optimization of isotope-labeling conditions for lambertellin based on isotope patterns observed by mass spectrometryQ46465549
Biosynthesis of 15N-labeled cylindrospermopsin and its application as internal standard in stable isotope dilution analysisQ46860730
Using stable isotope labeling to study the nitrogen metabolism in Anabaena flos-aquae growth and anatoxin biosynthesisQ47423953
Amino acid contents and transport in oilseed rape (Brassica napus L.) under different nitrogen conditionsQ48159446
Synthesis and Identification of Key Biosynthetic Intermediates for the Formation of the Tricyclic Skeleton of Saxitoxin.Q48330538
Chemistry of a Unique Polyketide-like SynthaseQ49488740
Genetic Analysis of Human Norovirus Strains in Japan in 2016-2017.Q49702596
Proteins with high turnover rate in barley leaves estimated by proteome analysis combined with in planta isotope labeling.Q51706782
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectDinoflagellataQ120490
P304page(s)3460
P577publication date2019-03-05
P1433published inScientific ReportsQ2261792
P1476titleMetabolomic study of saxitoxin analogues and biosynthetic intermediates in dinoflagellates using N-labelled sodium nitrate as a nitrogen source
P478volume9

Reverse relations

cites work (P2860)
Q6488787515N Stable Isotope Labeling PSTs in Alexandrium minutum for Application of PSTs as Biomarker.
Q89599052Biosynthesis of Saxitoxin in Marine Dinoflagellates: An Omics Perspective
Q90133633Identification of a Novel Saxitoxin Analogue, 12β-Deoxygonyautoxin 3, in the Cyanobacterium, Anabaena circinalis (TA04)

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