Autophagy controls p38 activation to promote cell survival under genotoxic stress

scientific article published on 4 December 2012

Autophagy controls p38 activation to promote cell survival under genotoxic stress is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M112.415224
P932PMC publication ID3548470
P698PubMed publication ID23212914

P50authorBenoit ViolletQ42482187
Lei QiangQ59687786
P2093author name stringYu-Ying He
Chunli Wu
Mei Ming
P2860cites workLC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formationQ24294635
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagyQ24312147
Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IPQ24314845
Network organization of the human autophagy systemQ24324004
AMPK phosphorylation of raptor mediates a metabolic checkpointQ24329244
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressorQ24569647
UVB-mediated activation of p38 mitogen-activated protein kinase enhances resistance of normal human keratinocytes to apoptosis by stabilizing cytoplasmic p53.Q40724097
Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cellsQ40955810
The regulation of ATF3 gene expression by mitogen-activated protein kinasesQ42104816
Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells.Q46421665
Activating transcription factor 3, a stress-inducible gene, suppresses Ras-stimulated tumorigenesisQ46937302
Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytesQ57082906
Involvement of P38 MAP kinase in the augmentation of UVB-mediated apoptosis via the epidermal platelet-activating factor receptorQ80164786
Specific regulation of cytokine-dependent p38 MAP kinase activation by p62/SQSTM1Q80763828
Hif-2alpha mediates UV-induced apoptosis through a novel ATF3-dependent death pathwayQ81358751
Selective autophagy: ubiquitin-mediated recognition and beyondQ84974064
The AMPK signalling pathway coordinates cell growth, autophagy and metabolismQ24616273
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cellsQ24671346
Autophagy: molecular machinery for self-eatingQ24678361
Autophagy in the Pathogenesis of DiseaseQ27860558
TOR signaling in growth and metabolismQ27860757
p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expressionQ28115373
p62 functions as a p38 MAP kinase regulatorQ28138047
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington diseaseQ28261987
Upstream and downstream of mTORQ28277365
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1Q28506431
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient miceQ28588080
The role of autophagy during the early neonatal starvation periodQ29547489
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagyQ29615616
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesisQ29617725
3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytesQ29617843
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphomaQ29622918
p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wastingQ30433011
Tor directly controls the Atg1 kinase complex to regulate autophagyQ33627273
The association of AMPK with ULK1 regulates autophagyQ33745164
Role of autophagy in cancer: management of metabolic stressQ33999458
G Protein betagamma subunits augment UVB-induced apoptosis by stimulating the release of soluble heparin-binding epidermal growth factor from human keratinocytesQ34634264
Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signallingQ35610059
Autophagy suppresses tumor progression by limiting chromosomal instabilityQ35812219
Antimalarial therapy prevents Myc-induced lymphomaQ36287308
Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brainQ36678446
Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulumQ36678530
Deconvoluting the context-dependent role for autophagy in cancerQ36876716
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomesQ37014368
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathiesQ37219529
AMPK in Health and DiseaseQ37543855
Autophagy and tumorigenesisQ37768714
AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cellsQ39733339
Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.Q39878605
AMP-activated protein kinase contributes to UV- and H2O2-induced apoptosis in human skin keratinocytesQ39948889
UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytesQ39986567
Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagyQ40052333
5'AMP-activated protein kinase alpha deficiency enhances stress-induced apoptosis in BHK and PC12 cellsQ40135196
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectgenotoxicityQ1009245
autophagyQ288322
P304page(s)1603-1611
P577publication date2012-12-04
P1433published inJournal of Biological ChemistryQ867727
P1476titleAutophagy controls p38 activation to promote cell survival under genotoxic stress
P478volume288

Reverse relations

cites work (P2860)
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