DNA immunization circumvents deficient induction of T helper type 1 and cytotoxic T lymphocyte responses in neonates and during early life

scientific article published on August 1997

DNA immunization circumvents deficient induction of T helper type 1 and cytotoxic T lymphocyte responses in neonates and during early life is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1997PNAS...94.8726M
P356DOI10.1073/PNAS.94.16.8726
P932PMC publication ID23100
P698PubMed publication ID9238045
P5875ResearchGate publication ID235610638

P2093author name stringBrandt C
Dougan G
Lambert PH
Siegrist CA
Tougne C
Wild F
Barrios C
Martinez X
Saddallah F
P2860cites workCpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gammaQ24568172
Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunizationQ24599495
Selective expression of an interleukin-12 receptor component by human T helper 1 cellsQ24670175
Immunostimulatory DNA sequences necessary for effective intradermal gene immunizationQ34384185
Immunization with plasmid DNA encoding for the measles virus hemagglutinin and nucleoprotein leads to humoral and cell-mediated immunityQ34407452
Photolysis of the carbon monoxide complex of myoglobin: nanosecond time-resolved crystallography.Q34408873
Immune response in mice following immunization with DNA encoding fragment C of tetanus toxin.Q35511588
Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunityQ36366499
Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cellsQ36376864
Measles virus haemagglutinin gene: cloning, complete nucleotide sequence analysis and expression in COS cellsQ36481562
Vaccinia virus recombinants expressing either the measles virus fusion or hemagglutinin glycoprotein protect dogs against canine distemper virus challengeQ36797309
Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaquesQ36952733
Induction of neonatal tolerance by plasmid DNA vaccination of miceQ37362104
Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptideQ37434689
Immune response to neonatal genetic immunizationQ41127211
Long-term persistence of plasmid DNA and foreign gene expression in mouse muscleQ41607156
Decreased interleukin-12 (IL-12) from activated cord versus adult peripheral blood mononuclear cells and upregulation of interferon-gamma, natural killer, and lymphokine-activated killer activity by IL-12 in cord blood mononuclear cellsQ42519883
DNA immunization of newborn mice with a plasmid-expressing nucleoprotein of influenza virusQ43469587
Induction of protective CTL responses in newborn mice by a murine retrovirusQ44865656
Passively administered antibody suppresses the induction of measles virus antibodies by vaccinia-measles recombinant virusesQ45787814
Evaluation of a protease activation mutant of Sendai virus as a potent live vaccineQ45880498
Role of antigen-presenting cells in the polarized development of helper T cell subsets: evidence for differential cytokine production by Th0 cells in response to antigen presentation by B cells and macrophagesQ46912975
Induction of TH1 and TH2 immunity in neonatal mice.Q52048769
Up-regulation of murine neonatal T helper cell responses by accessory cell factors.Q52056273
Biological and immunogenic properties of a canarypox-rabies recombinant, ALVAC-RG (vCP65) in non-avian species.Q52846225
Synthesis of T helper 2-type cytokines at the maternal-fetal interface.Q52885481
Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: predominance of a Th2-biased pattern which persists after adult boosting.Q52888854
Partial correction of the TH2/TH1 imbalance in neonatal murine responses to vaccine antigens through selective adjuvant effects.Q52891067
Heterologous and homologous protection against influenza A by DNA vaccination: optimization of DNA vectors.Q54649033
Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic CellsQ56338635
Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNAQ71396642
DNA vaccinesQ71504602
Autoimmunity following neonatal tolerance to alloantigens: role of donor I-A and I-E moleculesQ71880510
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cellsQ72191659
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectcytotoxicityQ246181
immunizationQ1415366
P304page(s)8726-8731
P577publication date1997-08-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleDNA immunization circumvents deficient induction of T helper type 1 and cytotoxic T lymphocyte responses in neonates and during early life
P478volume94

Reverse relations

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