GM1 ganglioside: another nuclear lipid that modulates nuclear calcium. GM1 potentiates the nuclear sodium-calcium exchanger

scientific article published on March 2006

GM1 ganglioside: another nuclear lipid that modulates nuclear calcium. GM1 potentiates the nuclear sodium-calcium exchanger is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1139/Y05-133
P698PubMed publication ID16902585

P2093author name stringGusheng Wu
Robert W Ledeen
P2860cites workPresence of sodium-calcium exchanger/GM1 complex in the nuclear envelope of non-neural cells: nature of exchanger-GM1 interaction.Q40468087
C6 cells express a sodium-calcium exchanger/GM1 complex in the nuclear envelope but have no exchanger in the plasma membrane: comparison to astrocytesQ40567687
A new Na/Ca exchanger splicing pattern identified in situ leads to a functionally active 70kDa NH(2)-terminal proteinQ40785723
Inositides and the nucleus and inositides in the nucleusQ40856677
Variable subcellular localization of glycosphingolipids.Q41574985
Functional analysis of a disulfide bond in the cardiac Na(+)-Ca(2+) exchangerQ41711555
Stimulation of nuclear sphingosine kinase activity by platelet-derived growth factorQ42826338
NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptorsQ42917771
Characterization of cholera toxin B subunit-induced Ca(2+) influx in neuroblastoma cells: evidence for a voltage-independent GM1 ganglioside-associated Ca(2+) channelQ44124997
Sodium/calcium exchanger subtypes NCX1, NCX2 and NCX3 show cell-specific expression in rat hippocampus culturesQ44212172
Identification of cholera toxin-binding sites in the nucleus of intestinal epithelial cellsQ44600249
Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: rescue by GM1 and LIGA20.Q45130172
Enhanced susceptibility to kainate-induced seizures, neuronal apoptosis, and death in mice lacking gangliotetraose gangliosides: protection with LIGA 20, a membrane-permeant analog of GM1.Q46818702
Developmental appearance of nuclear GM1 in neurons of the central and peripheral nervous systemsQ48162098
Potentiation of a sodium-calcium exchanger in the nuclear envelope by nuclear GM1 gangliosideQ48577116
Na,K-ATPase in the nuclear envelope regulates Na+: K+ gradients in hepatocyte nucleiQ48859495
Calcium release from the nucleus by InsP3 receptor channels.Q49075257
Characterization of nuclear gangliosides in rat brain: concentration, composition, and developmental changes.Q52124193
Gangliosides of sea urchin embryos. Their localization and participation in early development.Q52243911
Changes in rabbit brain cytosolic and membrane-bound gangliosides during prenatal life.Q52294875
Calcium orchestrates apoptosis.Q54055382
The nucleus is insulated from large cytosolic calcium ion changesQ59053398
Sodium-calcium exchange: a molecular perspectiveQ33938688
Nuclear phospholipase C and signalingQ34244229
Ganglioside GM1 binds to the Trk protein and regulates receptor functionQ34289656
Traveling for the glycosphingolipid pathQ34290912
Re-examination of the mechanisms regulating nuclear inositol lipid metabolismQ34369672
Cerebellar neurons lacking complex gangliosides degenerate in the presence of depolarizing levels of potassiumQ34595643
Nuclear lipid metabolism and signalingQ34720510
Ganglioside function in calcium homeostasis and signalingQ34955771
Functional role of phospholipids in the nuclear eventsQ34980909
Nuclear lipid signallingQ35120151
Nuclear lipids: key signaling effectors in the nervous system and other tissuesQ35574286
New aspects of nuclear calcium signallingQ35822670
The role of intranuclear lipids.Q35935663
Depletion of calcium from the lumen of endoplasmic reticulum reversibly inhibits passive diffusion and signal-mediated transport into the nucleusQ36235166
Gangliosides of the nuclear membrane: a crucial locus of cytoprotective modulationQ36366607
Active nuclear import and export is independent of lumenal Ca2+ stores in intact mammalian cellsQ36421285
Lipid-dependent nuclear signalling: morphological and functional features.Q36724939
ATP-dependent accumulation and inositol trisphosphate- or cyclic ADP-ribose-mediated release of Ca2+ from the nuclear envelopeQ39386361
P433issue3-4
P304page(s)393-402
P577publication date2006-03-01
P1433published inCanadian Journal of Physiology and PharmacologyQ5030248
P1476titleGM1 ganglioside: another nuclear lipid that modulates nuclear calcium. GM1 potentiates the nuclear sodium-calcium exchanger
P478volume84

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cites work (P2860)
Q38920622A new cell-penetrating peptide that blocks the autoinhibitory XIP domain of NCX1 and enhances antiporter activity
Q35416888Anti-ganglioside antibodies in amyotrophic lateral sclerosis revisited
Q36994575GM1 in the nuclear envelope regulates nuclear calcium through association with a nuclear sodium-calcium exchanger
Q38588644Interorganellar membrane microdomains: dynamic platforms in the control of calcium signaling and apoptosis
Q33682632Lysosomal multienzyme complex: pros and cons of working together
Q57060151Lysosomal storage diseases
Q52729770Mitochondria-associated ER membranes (MAMs) and lysosomal storage diseases.
Q36648248Nuclear Na+/K+-ATPase plays an active role in nucleoplasmic Ca2+ homeostasis
Q37535345Pathophysiological actions of neuropathy-related anti-ganglioside antibodies at the neuromuscular junction
Q36796685Sodium-calcium exchangers in the nucleus: an unexpected locus and an unusual regulatory mechanism
Q27004097The pre-synaptic motor nerve terminal as a site for antibody-mediated neurotoxicity in autoimmune neuropathies and synaptopathies
Q92193049Trends in Glycolipid Biomarker Discovery in Neurodegenerative Disorders by Mass Spectrometry

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