NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors

scientific article published on October 20, 2003

NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1083/JCB.200306134
P953full work available at URLhttps://rupress.org/jcb/article-pdf/163/2/271/1311279/jcb1632271.pdf
https://europepmc.org/articles/PMC2173522
https://europepmc.org/articles/PMC2173522?pdf=render
https://rupress.org/jcb/article-pdf/163/2/271/1868709/jcb1632271.pdf
P932PMC publication ID2173522
P698PubMed publication ID14568993
P5875ResearchGate publication ID231584324

P50authorOle Holger PetersenQ21165017
Alexei V TepikinQ59983506
P2093author name stringYoshio Maruyama
Kojiro Yano
Julia V. Gerasimenko
Oleg V. Gerasimenko
Nick J. Dolman
P2860cites workNature Reviews Molecular Cell BiologyQ1573120
Pharmacological ReviewsQ2085079
Nicotinate-adenine dinucleotide phosphate-induced Ca(2+)-release does not behave as a Ca(2+)-induced Ca(2+)-release systemQ24534332
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cellsQ28138792
NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggsQ28216586
Inositol trisphosphate and calcium signallingQ28262867
A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-riboseQ28306365
Potentiation and inhibition of Ca(2+) release-activated Ca(2+) channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP(3) receptorsQ28360565
Termination of cytosolic Ca2+ signals: Ca2+ reuptake into intracellular stores is regulated by the free Ca2+ concentration in the store lumenQ42636599
Novel biochemical and functional insights into nuclear Ca(2+) transport through IP(3)Rs and RyRs in osteoblastsQ42802061
A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasisQ42808493
Calcium uptake via endocytosis with rapid release from acidifying endosomes.Q42823932
Nicotinic acid-adenine dinucleotide phosphate activates the skeletal muscle ryanodine receptorQ43002260
Fast biphasic regulation of type 3 inositol trisphosphate receptors by cytosolic calciumQ43903268
Calcium signalling: more messengers, more channels, more complexityQ44113649
Ryanodine receptor type I and nicotinic acid adenine dinucleotide phosphate receptors mediate Ca2+ release from insulin-containing vesicles in living pancreatic beta-cells (MIN6).Q44285317
The distribution of the endoplasmic reticulum in living pancreatic acinar cells.Q44288130
Effects of 1-methyladenine on nuclear Ca2+ transients and meiosis resumption in starfish oocytes are mimicked by the nuclear injection of inositol 1,4,5-trisphosphate and cADP-riboseQ48956036
Changes in either cytosolic or nucleoplasmic inositol 1,4,5-trisphosphate levels can control nuclear Ca2+ concentrationQ49061136
Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells.Q51725359
Sequential-replenishment mechanism of exocytosis in pancreatic aciniQ57861706
Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphateQ63387803
Receptor-activated cytoplasmic Ca2+ spiking mediated by inositol trisphosphate is due to Ca2(+)-induced Ca2+ releaseQ67677043
The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of proteinQ68256578
Effects of ryanodine in skinned cardiac cellsQ68947466
Inositol 1,4,5-trisphosphate receptor is located to the inner nuclear membrane vindicating regulation of nuclear calcium signaling by inositol 1,4,5-trisphosphate. Discrete distribution of inositol phosphate receptors to inner and outer nuclear membQ70870915
Nicotinate adenine dinucleotide phosphate (NAADP) triggers a specific calcium release system in sea urchin eggsQ72536435
Non-uniform distribution of mitochondria in pancreatic acinar cellsQ73601455
Differential involvement of vacuolar H(+)-ATPase in the refilling of thapsigargin- and agonist-mobilized Ca(2+) storesQ73754378
Subcellular Ca(2+) DynamicsQ73967429
The calcium store in the nuclear envelopeQ74589675
An examination of the secretion-like coupling model for the activation of the Ca2+ release-activated Ca2+ current I(CRAC) in RBL-1 cellsQ28361709
Energized mitochondria increase the dynamic range over which inositol 1,4,5-trisphosphate activates store-operated calcium influx.Q28366124
Calcium signalling: dynamics, homeostasis and remodellingQ29547635
Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF proteinQ29618202
Specific Ca2+ signaling evoked by cholecystokinin and acetylcholine: the roles of NAADP, cADPR, and IP3.Q31963644
Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cellsQ33661004
New Ca2+-releasing messengers: are they important in the nervous system?Q33756111
An inositol 1,4,5-trisphosphate-sensitive Ca2+ pool in liver nucleiQ33777321
Stereospecific inositol 1,4,5-[32P]trisphosphate binding to isolated rat liver nuclei: evidence for inositol trisphosphate receptor-mediated calcium release from the nucleusQ33913373
Local uncaging of caged Ca(2+) reveals distribution of Ca(2+)-activated Cl(-) channels in pancreatic acinar cells.Q33943984
Coupling of the IP3 receptor/Ca2+ channel with Ca2+ storage proteins chromogranins A and B in secretory granulesQ34001977
A dynamic model of the type-2 inositol trisphosphate receptorQ34013433
The comeback of mitochondria to calcium signallingQ34104027
The endoplasmic reticulum: one continuous or several separate Ca(2+) stores?Q34224635
Nuclear pore complexes: dynamics in unexpected placesQ34305908
Caffeine-induced inhibition of inositol(1,4,5)-trisphosphate-gated calcium channels from cerebellumQ34439930
Nicotinic acid adenine dinucleotide phosphate: a new intracellular second messenger?Q34628924
Polarized calcium and calmodulin signaling in secretory epitheliaQ34711235
Depletion of calcium from the lumen of endoplasmic reticulum reversibly inhibits passive diffusion and signal-mediated transport into the nucleusQ36235166
Ca2+-activated K+-channels in the nuclear envelope isolated from single pancreatic acinar cellsQ36693713
ATP-dependent accumulation and inositol trisphosphate- or cyclic ADP-ribose-mediated release of Ca2+ from the nuclear envelopeQ39386361
Ca(2+) dynamics in the lumen of the endoplasmic reticulum in sensory neurons: direct visualization of Ca(2+)-induced Ca(2+) release triggered by physiological Ca(2+) entryQ39646604
Transformation of local Ca2+ spikes to global Ca2+ transients: the combinatorial roles of multiple Ca2+ releasing messengersQ39646750
Mitochondria are morphologically and functionally heterogeneous within cells.Q39646958
Two different but converging messenger pathways to intracellular Ca(2+) release: the roles of nicotinic acid adenine dinucleotide phosphate, cyclic ADP-ribose and inositol trisphosphateQ39958870
The pharmacology of intracellular Ca(2+)-release channelsQ40527842
Calcium and hormone actionQ40660663
Besides affecting intracellular calcium signaling, 2-APB reversibly blocks gap junctional coupling in confluent monolayers, thereby allowing measurement of single-cell membrane currents in undissociated cellsQ40665591
NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cellsQ40672258
Molecular and cellular physiology of intracellular calcium storesQ40674713
Cyclic ADP-ribose regulation of ryanodine receptors involved in agonist evoked cytosolic Ca2+ oscillations in pancreatic acinar cells.Q40791699
Calcium regulation of nuclear pore permeabilityQ40858038
Nuclear Ca2+ concentration measured with specifically targeted recombinant aequorinQ40875238
Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channelsQ40896605
Different patterns of receptor-activated cytoplasmic Ca2+ oscillations in single pancreatic acinar cells: dependence on receptor type, agonist concentration and intracellular Ca2+ buffering.Q41080006
Cytoplasmic Ca2+ oscillations evoked by receptor stimulation, G-protein activation, internal application of inositol trisphosphate or Ca2+: simultaneous microfluorimetry and Ca2+ dependent Cl- current recording in single pancreatic acinar cellsQ41204025
The pharmacology of ryanodine and related compounds.Q41402480
A Ca2+ release mechanism gated by the novel pyridine nucleotide, NAADP.Q41468938
The endoplasmic reticulum Ca2+ store: a view from the lumenQ41710104
Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive poolQ41865560
The Golgi apparatus is an inositol 1,4,5-trisphosphate-sensitive Ca2+ store, with functional properties distinct from those of the endoplasmic reticulumQ42000247
Spatial characterisation of ryanodine-induced calcium release in mouse pancreatic acinar cellsQ42129837
Long distance communication between muscarinic receptors and Ca2+ release channels revealed by carbachol uncaging in cell-attached patch pipetteQ42438814
Polarized expression of Ca2+ channels in pancreatic and salivary gland cells. Correlation with initiation and propagation of [Ca2+]i wavesQ42439757
Localized Ca2+ uncaging reveals polarized distribution of Ca2+-sensitive Ca2+ release sites: mechanism of unidirectional Ca2+ wavesQ42523763
Nuclear calcium signalling by individual cytoplasmic calcium puffsQ42633868
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)271-282
P577publication date2003-10-20
P1433published inJournal of Cell BiologyQ1524550
P1476titleNAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors
P478volume163

Reverse relations

cites work (P2860)
Q38291664Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release
Q27025044Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling
Q28294394An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals
Q39598749An emerging role for NAADP-mediated Ca2+ signaling in the pancreatic β-cell
Q38226562An integrated mechanism of cardiomyocyte nuclear Ca(2+) signaling
Q34000580Bile acids induce Ca2+ release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors
Q38202209Ca(2+) signals, NAADP and two-pore channels: role in cellular differentiation
Q42156376Ca2+ accumulation into acidic organelles mediated by Ca2+- and vacuolar H+-ATPases in human platelets
Q43258173Ca2+ release triggered by NAADP in hepatocyte microsomes
Q36554212Ca2+-stores in sperm: their identities and functions.
Q37617084Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release
Q41467010Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation
Q26823072Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches
Q35822230Calcium at fertilization and in early development
Q38969543Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes
Q36651062Calcium pathway machinery at fertilization in echinoderms
Q34203749Calcium signaling in synapse-to-nucleus communication
Q34552073Calcium signaling of pancreatic acinar cells in the pathogenesis of pancreatitis
Q36790538Calcium signalling and pancreatic cell death: apoptosis or necrosis?
Q36255273Calcium signalling by nicotinic acid adenine dinucleotide phosphate (NAADP).
Q28591507Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors
Q34937098Contribution of NADPH oxidase to membrane CD38 internalization and activation in coronary arterial myocytes
Q37704928Cyclic ADP-Ribose and NAADP in Vascular Regulation and Diseases
Q38245455Decoding calcium signaling across the nucleus
Q39646703Differential redistribution of Ca2+-handling proteins during polarisation of MDCK cells: Effects on Ca2+ signalling
Q42959504Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals
Q28250269Domain assembly of NAADP-gated two-pore channels
Q42808510Dual sensitivity of sarcoplasmic/endoplasmic Ca2+-ATPase to cytosolic and endoplasmic reticulum Ca2+ as a mechanism of modulating cytosolic Ca2+ oscillations.
Q24316454Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling
Q28287124Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology
Q50283631Frontrunners of T cell activation: Initial, localized Ca2+ signals mediated by NAADP and the type 1 ryanodine receptor.
Q46548901Functional metabotropic glutamate receptors on nuclei from brain and primary cultured striatal neurons. Role of transporters in delivering ligand
Q46387081Functional ryanodine receptor expression is required for NAADP-mediated local Ca2+ signaling in T-lymphocytes.
Q36562730GM1 ganglioside: another nuclear lipid that modulates nuclear calcium. GM1 potentiates the nuclear sodium-calcium exchanger
Q37513754Homer and the ryanodine receptor
Q48568852IP3-dependent nuclear Ca2+ signalling in the mammalian heart
Q34190629InsP3 signaling induces pulse-modulated Ca2+ signals in the nucleus of airway epithelial ciliated cells.
Q88320325Integration of nicotinic acid adenine dinucleotide phosphate (NAADP)-dependent calcium signalling
Q37942052Intracellular organelles in the saga of Ca2+ homeostasis: different molecules for different purposes?
Q37292810Investigating cADPR and NAADP in intact and broken cell preparations
Q42130020Involvement of P2X receptors in the NAD(+)-induced rise in [Ca (2+)] (i) in human monocytes
Q28265293Linking NAADP to ion channel activity: a unifying hypothesis
Q33840424Lysosome-dependent Ca(2+) release response to Fas activation in coronary arterial myocytes through NAADP: evidence from CD38 gene knockouts
Q45032464Lysosome-sarcoplasmic reticulum junctions. A trigger zone for calcium signaling by nicotinic acid adenine dinucleotide phosphate and endothelin-1.
Q34883560Malignant hyperthermia: a pharmacogenetic disorder
Q28305783Messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiation
Q34467099Monovalent cationic channel activity in the inner membrane of nuclei from skeletal muscle fibers
Q42497166NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells
Q42815147NAADP binding to its target protein in sea urchin eggs requires phospholipids
Q42076235NAADP induces pH changes in the lumen of acidic Ca2+ stores
Q24318546NAADP mobilizes calcium from acidic organelles through two-pore channels
Q50698075NAADP mobilizes calcium from the endoplasmic reticular Ca(2+) store in T-lymphocytes.
Q53403701NAADP regulates human platelet function.
Q37229250NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist
Q33596032Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-Lymphocytes
Q41815298Nicotinic acid adenine dinucleotide phosphate (NAADP) degradation by alkaline phosphatase
Q36217193Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling
Q36890713Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by β-adrenergic stimulation
Q36648248Nuclear Na+/K+-ATPase plays an active role in nucleoplasmic Ca2+ homeostasis
Q40179587Nuclear localization of functional metabotropic glutamate receptor mGlu1 in HEK293 cells and cortical neurons: role in nuclear calcium mobilization and development
Q36662666Nuclear sphingolipids: metabolism and signaling
Q38083888Nucleoplasmic calcium signaling and cell proliferation: calcium signaling in the nucleus
Q80497629Nucleoplasmic reticulum is not essential in nuclear calcium signalling mediated by cyclic ADPribose in primary neurons
Q37294792Orais and STIMs: physiological mechanisms and disease
Q37227943Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors
Q37147714Pancreatitis and calcium signalling: report of an international workshop.
Q46849872Physical properties of two types of calcium stores and SERCAs in human platelets.
Q38872878Preferential Coupling of the NAADP Pathway to Exocytosis in T-Cells.
Q44917284Production of NAADP and its role in Ca2+ mobilization associated with lysosomes in coronary arterial myocytes
Q33816664Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking
Q45957021Recruitment of NAADP-sensitive acidic Ca2+ stores by glutamate.
Q43981218Regulation of nuclear Ca2+ signaling by translocation of the Ca2+ messenger synthesizing enzyme ADP-ribosyl cyclase during neuronal depolarization.
Q37730290Review: NAD +: a modulator of immune functions
Q37970419Role of the nuclear envelope in calcium signalling
Q38017031Roles of cADPR and NAADP in pancreatic cells
Q36493307Route of glucocorticoid-induced macromolecules across the nuclear envelope as viewed by atomic force microscopy
Q48586012Selective inhibition of spontaneous but not Ca2+ -dependent release machinery by presynaptic group II mGluRs in rat cerebellar slices
Q37229265Sodium-calcium exchanger complexed with GM1 ganglioside in nuclear membrane transfers calcium from nucleoplasm to endoplasmic reticulum
Q24642734Sperm express a Ca2+-regulated NAADP synthase
Q50672008Steroids dilate nuclear pores imaged with atomic force microscopy.
Q51893719Structural evidence for perinuclear calcium microdomains in cardiac myocytes.
Q33840138TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP
Q37118266TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytes
Q42940716The Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex?
Q35841898The NAADP receptor: commentary on Billington et al.
Q28256879The hunt for an alternate way to generate NAADP. Focus on "NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells"
Q26865292The role of Ca2+ in the pathophysiology of pancreatitis
Q37349965The role of dietary niacin intake and the adenosine-5'-diphosphate-ribosyl cyclase enzyme CD38 in spatial learning ability: is cyclic adenosine diphosphate ribose the link between diet and behaviour?
Q34131094The ryanodine receptor is expressed in human pancreatic acinar cells and contributes to acinar cell injury
Q28585336The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores
Q41819567Time sensing by NAADP receptors.
Q36093938Twenty years of calcium imaging: cell physiology to dye for.
Q34065665Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals
Q39412197cAMP-dependent recruitment of acidic organelles for Ca2+ signaling in the salivary gland

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