Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells (scientific article)

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Q37145705	Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions
Q40786543	Drug sequestration in cytoplasmic organelles does not contribute to the diminished sensitivity of anthracyclines in multidrug resistant K562 cells
Q41932269	Dynamic measurements of the acute and chronic effects of lysosomotropic agents on hepatocyte lysosomal pH using flow cytometry
Q33868877	Early acidification of phagosomes containing Brucella suis is essential for intracellular survival in murine macrophages.
Q35104639	Early, H+-V-ATPase-dependent proton flux is necessary for consistent left-right patterning of non-mammalian vertebrates
Q24301618	Ebola virus uses clathrin-mediated endocytosis as an entry pathway
Q73604830	Effect of acute increases in filtered HCO3- on renal hydrogen transporters: II. H(+)-ATPase
Q43605812	Effect of bafilomycin A1, a specific inhibitor of vacuolar (V-type) proton ATPases, on the capacitation of rabbit spermatozoa
Q42255479	Effect of increasing intravesicular pH on nitrite production and leishmanicidal activity of activated macrophages
Q34060367	Effect of omeprazole, an inhibitor of H+,K(+)-ATPase, on bone resorption in humans
Q40270260	Effects of ATPase inhibitors on the response of HeLa cells to Helicobacter pylori vacuolating toxin.
Q30722232	Effects of Bafilomycin A1 and Metabolic Inhibitors on the Maintenance of Vacuolar Acidity in Maize Root Hair Cells
Q71961711	Effects of Bafilomycin A1 on Cytosolic pH of sheep Alveolar and Peritoneal Macrophages: Evaluation of the pH-Regulatory Role of Plasma Membrane V-ATPases
Q42504932	Effects of bafilomycin A1 and amiloride on the apical potassium and proton gradients in Drosophila Malpighian tubules studied by X-ray microanalysis and microelectrode measurements
Q40285836	Effects of dirithromycin and erythromycylamine on human neutrophil degranulation
Q36638410	Effects of estrogen on proton secretion via the apical membrane in vaginal-ectocervical epithelial cells of postmenopausal women
Q43600609	Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
Q41735986	Effects of reduced vesicular filling on synaptic transmission in rat hippocampal neurones.
Q39591317	Efficient DNA transfection mediated by the C-terminal domain of human immunodeficiency virus type 1 viral protein R
Q97412728	Efficient Preparation of Bafilomycin A1 from Marine Streptomyces lohii Fermentation Using Three-Phase Extraction and High-Speed Counter-Current Chromatography
Q46856395	Efficient execution of cell death in non-glycolytic cells requires the generation of ROS controlled by the activity of mitochondrial H+-ATP synthase
Q33526436	Electrophysiological characterization of ATPases in native synaptic vesicles and synaptic plasma membranes
Q35549166	Elevation of vacuolar pH inhibits the cytotoxic activity of furin-cleaved exotoxin A.
Q45357434	Endocytic processing of adeno-associated virus type 8 vectors for transduction of target cells
Q39387594	Endocytosis and trafficking of human lactoferrin in macrophage-like human THP-1 cells (1).
Q34351730	Endocytosis is a critical step in entry of subgroup B avian leukosis viruses.
Q39745537	Endosomal dynamics of Met determine signaling output
Q37376783	Endosome acidification and receptor trafficking: bafilomycin A1 slows receptor externalization by a mechanism involving the receptor's internalization motif
Q26992067	Endosome maturation
Q42442529	Energy turnover of vascular endothelial cells
Q73791112	Energy-dependent accumulation of calcium antagonists in catecholamine storage vesicles
Q28551823	Engineering an Anti-Transferrin Receptor ScFv for pH-Sensitive Binding Leads to Increased Intracellular Accumulation
Q90194187	Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression
Q34124112	Enhanced delivery of exogenous peptides into the class I antigen processing and presentation pathway
Q33848083	Enhanced efficacy of photodynamic therapy via a sequential targeting protocol
Q34140422	Enhanced expression of the human vacuolar H+-ATPase c subunit gene (ATP6L) in response to anticancer agents.
Q35094530	Enhanced real-time monitoring of adeno-associated virus trafficking by virus-quantum dot conjugates
Q47200065	Enhancement of natural killer activity and IFN-γ production in an IL-12-dependent manner by a Brassica rapa L.
Q35194907	Enhancing gene delivery of adeno-associated viruses by cell-permeable peptides
Q92727065	Entry of Challenge Virus Standard (CVS) -11 into N2a cells via a clathrin-mediated, cholesterol-, dynamin-, pH-dependent endocytic pathway
Q40046346	Entry of poliovirus into cells does not require a low-pH step.
Q36898654	Enzootic nasal tumor virus envelope requires a very acidic pH for fusion activation and infection.
Q50136458	Enzymatic characterization of FliI. An ATPase involved in flagellar assembly in Salmonella typhimurium
Q42960230	Essential role of vesicular nucleotide transporter in vesicular storage and release of nucleotides in platelets
Q45326430	Estimating the rotation rate in the vacuolar proton-ATPase in native yeast vacuolar membranes
Q36681330	Estrogen acidifies vaginal pH by up-regulation of proton secretion via the apical membrane of vaginal-ectocervical epithelial cells
Q72899291	Ethinyl estradiol decreases acidification of rat liver endocytic vesicles
Q39975416	Evaluation of the effect of vector architecture on DNA condensation and gene transfer efficiency
Q54038239	Evidence for a K+ channel in bovine chromaffin granule membranes: single-channel properties and possible bioenergetic significance.
Q41202107	Evidence for vacuolar-type proton pumps in nonmitochondrial and inositol 1,4,5-trisphosphate-sensitive calcium stores of insulin-secreting cells
Q41369369	Evidence that the thyrotropin-releasing hormone receptor and its ligand are recycled dissociated from each other
Q41258132	Exchanging the extracellular domain of amyloid precursor protein for horseradish peroxidase does not interfere with alpha-secretase cleavage of the beta-amyloid region, but randomizes secretion in Madin-Darby canine kidney cells
Q33725968	Excitability and synaptic communication within the oligodendrocyte lineage
Q42075014	Exocytosis of ATP from astrocyte progenitors modulates spontaneous Ca2+ oscillations and cell migration.
Q74158051	Expression and characterization of a Synechocystis PCC 6803 P-type ATPase in E. coli plasma membranes
Q36135389	Expression of 16 kDa proteolipid of vacuolar-type H(+)-ATPase in human pancreatic cancer
Q24796021	Expression of a prokaryotic P-type ATPase in E. coli plasma membranes and purification by Ni2+-affinity chromatography
Q37125290	Expression of human papilloma virus type 16 E5 protein in amelanotic melanoma cells regulates endo-cellular pH and restores tyrosinase activity
Q42837745	Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
Q67898769	Expression of the yeast plasma membrane [H+]ATPase in secretory vesicles. A new strategy for directed mutagenesis
Q42473340	Extracellular protons differentially potentiate the responses of native AMPA receptor subtypes regulating neurotransmitter release
Q47149285	F-actin reorganization by V-ATPase inhibition in prostate cancer.
Q73968904	FD-891, a structural analogue of concanamycin A that does not affect vacuolar acidification or perforin activity, yet potently prevents cytotoxic T lymphocyte-mediated cytotoxicity through the blockage of conjugate formation
Q36046404	FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1.
Q27486208	Fc receptor-mediated, antibody-dependent enhancement of bacteriophage lambda-mediated gene transfer in mammalian cells
Q34335805	Fgf8-related secondary organizers exert different polarizing planar instructions along the mouse anterior neural tube.
Q46626879	Flufenamic acid affects multiple currents and causes intracellular Ca2+ release in Aplysia bag cell neurons
Q43716843	Fluorescent verapamil analogue for monitoring acidic intracellular organelles in multidrug resistant and sensitive cells
Q42542379	Formamicin, a novel antifungal antibiotic produced by a strain of Saccharothrix sp. I. Taxonomy, production, isolation and biological properties.
Q42456411	Functional expression of a vacuolar-type H+-ATPase in the plasma membrane and intracellular vacuoles of Trypanosoma cruzi
Q35873387	Functional properties of the uptake of amines in immortalised peptidergic neurones (transport-P).
Q38351713	Functionalized polystyrene nanoparticles as a platform for studying bio-nano interactions.
Q59447842	Further Evidence for Stachyose and Sucrose/H+ Antiporters on the Tonoplast of Japanese Artichoke (Stachys sieboldii) Tubers
Q36234415	G-protein ligands inhibit in vitro reactions of vacuole inheritance
Q68430927	GTP-induced fusion of isolated pancreatic microsomal vesicles is increased by acidification of the vesicle lumen
Q36105134	Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation
Q35384428	Genetic and cell biological aspects of the yeast vacuolar H(+)-ATPase
Q46937496	Glial cell-derived glutamate mediates autocrine cell volume regulation in the retina: activation by VEGF.
Q39158612	Glucosylceramide modulates endolysosomal pH in Gaucher disease
Q40790058	Glucosylceramide synthesis inhibitors block pharmacologically induced dispersal of the Golgi and anterograde membrane flow from the endoplasmic reticulum: implication of sphingolipid metabolism in maintenance of the Golgi architecture and anterograd
Q41820272	Golgi alkalinization by the papillomavirus E5 oncoprotein
Q42827804	Group IB secretory phospholipase A2 promotes matrix metalloproteinase-2-mediated cell migration via the phosphatidylinositol 3-kinase and Akt pathway
Q67488876	H+ extrusion by an apical vacuolar-type H+-ATPase in rat renal proximal tubules
Q36814754	HCO3-dependent pHi regulation in tracheal epithelial cells
Q30634144	HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus
Q33701989	HIV-1-Tat excites cardiac parasympathetic neurons of nucleus ambiguus and triggers prolonged bradycardia in conscious rats
Q33727577	Herpesvirus Entry into Host Cells Mediated by Endosomal Low pH.
Q79800165	Heterogeneity of the vacuolar pyrophosphatase protein from Chenopodium rubrum
Q92835738	High-resolution detection of ATP release from single cultured mouse dorsal horn spinal cord glial cells and its modulation by noradrenaline
Q35353325	High-throughput screening platform for natural product-based drug discovery against 3 neglected tropical diseases: human African trypanosomiasis, leishmaniasis, and Chagas disease.
Q42482259	Histamine depletion does not affect pancreastatin secretion from isolated rat stomach ECL cells
Q34314221	Histamine-mediated increases in cytosolic [Ca2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells
Q46903428	Histidine-mediated xylem loading of zinc is a species-wide character in Noccaea caerulescens.
Q34456743	Histidine-rich peptides and polymers for nucleic acids delivery
Q39541959	Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides
Q42941738	Histoplasma capsulatum modulates the acidification of phagolysosomes
Q37693338	How MHC class II molecules reach the endocytic pathway
Q48163816	Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals.
Q34301880	Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion
Q36289031	Human cytomegalovirus uses two distinct pathways to enter retinal pigmented epithelial cells
Q30307077	Human immunodeficiency virus type 1 particles pseudotyped with envelope proteins that fuse at low pH no longer require Nef for optimal infectivity
Q34340830	Human platelet dense granules contain polyphosphate and are similar to acidocalcisomes of bacteria and unicellular eukaryotes.
Q35860935	Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking
Q28573716	Hydrophobic bile salts trigger ceramide formation through endosomal acidification
Q33484022	Hydrostatic pressure promotes the acidification of vacuoles inSaccharomyces cerevisiae
Q39692502	Hygrobafilomycin, a cytotoxic and antifungal macrolide bearing a unique monoalkylmaleic anhydride moiety, from Streptomyces varsoviensis
Q36160407	Hyperspectral Imaging Using Intracellular Spies: Quantitative Real-Time Measurement of Intracellular Parameters In Vivo during Interaction of the Pathogenic Fungus Aspergillus fumigatus with Human Monocytes
Q39153043	IL-12 and IL-27 regulate the phagolysosomal pathway in mycobacteria-infected human macrophages
Q27934808	Identification and characterization of Vnx1p, a novel type of vacuolar monovalent cation/H+ antiporter of Saccharomyces cerevisiae
Q28217034	Identification of a factor that links apoptotic cells to phagocytes
Q27936461	Identification of a gene for a polyamine transport protein in yeast
Q38862240	Identification of a lung cancer cell line deficient in atg7-dependent autophagy
Q44565970	Identification of a new chondropsin class of antitumor compound that selectively inhibits V-ATPases
Q34091383	Imaging multiple intermediates of single-virus membrane fusion mediated by distinct fusion proteins
Q73323232	Immunolocalization of proton-ATPase in the gills of the elasmobranch, Squalus acanthias
Q83225617	Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo
Q42804744	In bafilomycin A1-resistant cells, bafilomycin A1 raised lysosomal pH and both prodigiosins and concanamycin A inhibited growth through apoptosis
Q28369524	In vitro activities of free and liposomal drugs against Mycobacterium avium-M. intracellulare complex and M. tuberculosis
Q41930505	In vitro fusion of endocytic vesicles: effects of reagents that alter endosomal pH.
Q36236283	In vitro reconstitution of cytoplasm to vacuole protein targeting in yeast
Q73486513	In vivo rapid reduction of alloantigen-activated CD8+ mature cytotoxic T cells by inhibitors of acidification of intracellular organelles, prodigiosin 25-C and concanamycin B
Q37033090	Inactivation of rho GTPases by statins attenuates anthrax lethal toxin activity
Q40675083	Increase in secretion of glial cell line-derived neurotrophic factor from glial cell lines by inhibitors of vacuolar ATPase
Q44443800	Increased tumour extracellular pH induced by Bafilomycin A1 inhibits tumour growth and mitosis in vivo and alters 5-fluorouracil pharmacokinetics
Q53552776	Increased valinomycin production in mutants of Streptomyces sp. M10 defective in bafilomycin biosynthesis and branched-chain α-keto acid dehydrogenase complex expression.
Q33825385	Induction of apoptosis by Sindbis virus occurs at cell entry and does not require virus replication.
Q44615924	Induction of neurite outgrowth of PC12 cells by an inhibitor of vacuolar H(+)-ATPase, bafilomycin A1.
Q41494084	Induction of phagocytic activity of M1 cells by an inhibitor of vacuolar H+-ATPase, bafilomycin A1.
Q35105641	Induction of type I interferon signaling determines the relative pathogenicity of Staphylococcus aureus strains.
Q51336052	Infection by Zika viruses requires the transmembrane protein AXL, endocytosis and low pH.
Q33851643	Infectious entry by amphotropic as well as ecotropic murine leukemia viruses occurs through an endocytic pathway
Q39589898	Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors
Q44054986	Influence of ANG II on cytoplasmic sodium in cultured rabbit nonpigmented ciliary epithelium
Q36984268	Influence of histidine incorporation on buffer capacity and gene transfection efficiency of HPMA-co-oligolysine brush polymers
Q36555298	Influenza A virus-induced early activation of ERK and PI3K mediates V-ATPase-dependent intracellular pH change required for fusion
Q34348512	Influenza virus can enter and infect cells in the absence of clathrin-mediated endocytosis
Q37462540	Inhibiting autophagy increases epirubicin's cytotoxicity in breast cancer cells
Q36301420	Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness.
Q42126221	Inhibition of Ca2+ release from Trypanosoma brucei acidocalcisomes by 3,5-dibutyl-4-hydroxytoluene: role of the Na+/H+ exchanger
Q35706815	Inhibition of Ebola and Marburg Virus Entry by G Protein-Coupled Receptor Antagonists
Q41880567	Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore.
Q28360301	Inhibition of Na+-H+ exchanger-3 interferes with apical receptor-mediated endocytosis via vesicle fusion
Q37442973	Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons
Q41517909	Inhibition of cell growth by bafilomycin A1, a selective inhibitor of vacuolar H(+)-ATPase
Q24338482	Inhibition of macroautophagy triggers apoptosis
Q42269980	Inhibition of mitogen-induced DNA synthesis by bafilomycin A1 in Swiss 3T3 fibroblasts.
Q38704678	Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells.
Q57269820	Inhibition of the vacuolar H+-ATPase perturbs the transport, sorting, processing and release of regulated secretory proteins
Q44298202	Inhibition of the yeast V-type ATPase by cytosolic ADP.
Q40285852	Inhibition of vacuolar-type (H+)-ATPase by the cytostatic macrolide apicularen A and its role in apicularen A-induced apoptosis in RAW 264.7 cells
Q50519141	Inhibitors of V-type ATPases, bafilomycin A1 and concanamycin A, protect against beta-amyloid-mediated effects on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.
Q39434688	Inhibitors of intravesicular acidification protect against Shiga toxin in a pH-independent manner
Q39802163	Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory-pathway proteins
Q89864744	Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells
Q37718852	Innate immunity to adenovirus
Q39523437	Inorganic cation transport and energy transduction in Enterococcus hirae and other streptococci
Q40463902	Insertion of targeting domains into the envelope glycoprotein of Moloney murine leukemia virus (MoMLV)-based vectors modulates the route of mCAT-1-mediated viral entry.
Q35031898	Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells
Q91137012	Insights into the release mechanism of astrocytic glutamate evoking in neurons NMDA receptor-mediated slow depolarizing inward currents
Q42982981	Interaction of dibutyltin-3-hydroxyflavone bromide with the 16 kDa proteolipid indicates the disposition of proton translocation sites of the vacuolar ATPase
Q48401229	Interaction of the clathrin-coated vesicle V-ATPase with ADP and sodium azide
Q39604793	Internalization of Sambucus nigra agglutinins I and II in insect midgut CF-203 cells
Q36799181	Intra-Golgi transport inhibition by megalomicin.
Q48051315	Intracellular Ca2+ pool content and signaling and expression of a calcium pump are linked to virulence in Leishmania mexicana amazonesis amastigotes
Q42822091	Intracellular Ca2+ storage in acidocalcisomes of Trypanosoma cruzi
Q34237847	Intracellular Vibrio parahaemolyticus escapes the vacuole and establishes a replicative niche in the cytosol of epithelial cells
Q35216845	Intracellular angiotensin II activates rat myometrium.
Q35310056	Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide
Q36436029	Intracellular endothelin type B receptor-driven Ca2+ signal elicits nitric oxide production in endothelial cells.
Q52542835	Intracellular pH regulation by the plasma membrane V-ATPase in Malpighian tubules of Drosophila larvae.
Q36218205	Intracellular trafficking of nonviral vectors
Q36340735	Intranuclear delivery of an antiviral peptide mediated by the B subunit of Escherichia coli heat-labile enterotoxin.
Q37113422	Intravesicular acidification correlates with binding of ADP-ribosylation factor to microsomal membranes
Q46533583	Intravesicular calcium release mediates the motion and exocytosis of secretory organelles: a study with adrenal chromaffin cells
Q36128722	Investigation of endosome and lysosome biology by ultra pH-sensitive nanoprobes
Q67488522	Involvement of a non‐proton pump factor (possibly Donnan‐type equilibrium) in maintenance of an acidic pH in lysosomes
Q35892408	Involvement of lysosomal dysfunction in silver nanoparticle-induced cellular damage in A549 human lung alveolar epithelial cells
Q35556685	Involvement of p21racA, phosphoinositide 3-kinase, and vacuolar ATPase in phagocytosis of bacteria and erythrocytes by Entamoeba histolytica: suggestive evidence for coincidental evolution of amebic invasiveness.
Q44527918	Ion regulation in the different life stages of Trypanosoma cruzi
Q36014556	Isolation Driven Divergence in Osmoregulation in Galaxias maculatus (Jenyns, 1848) (Actinopterygii: Osmeriformes).
Q33956805	Isolation and characterization of PEP5, a gene essential for vacuolar biogenesis in Saccharomyces cerevisiae
Q71991569	Isolation and characterization of new 18-membered macrolides FD-891 and FD-892
Q39939513	Isolation and characterization of the high-affinity K(+)-translocating ATPase from Rhodobacter sphaeroides
Q43831733	Isolation and structural determination of a new macrolide, makinolide, from the newly isolated Streptomyces sp. MK-30.
Q85706855	Isolation and structural determination of makinolide B from Streptomyces sp. MK-19
Q68033702	Isolation, characterization and biological activities of concanamycins as inhibitors of lysosomal acidification
Q36483877	Jaagsiekte sheep retrovirus utilizes a pH-dependent endocytosis pathway for entry.
Q42984444	Japanese encephalitis virus infection in Vero cells: the involvement of intracellular acidic vesicles in the early phase of viral infection was observed with the treatment of a specific vacuolar type H+-ATPase inhibitor, bafilomycin A1.
Q36506756	Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism
Q39776421	Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) infection of human fibroblast cells occurs through endocytosis
Q72098072	Kinetics of endosomal pH evolution in Dictyostelium discoideum amoebae Study by fluorescence spectroscopy
Q71567625	Kinetics of receptor-mediated endocytosis of albumin in cells derived from the proximal tubule of the kidney (opossum kidney cells): influence of Ca2+ and cAMP
Q35828541	Labeling HIV-1 virions with two fluorescent proteins allows identification of virions that have productively entered the target cell
Q55716663	Lanyamycin, a macrolide antibiotic from Sorangium cellulosum, strain Soce 481 (Myxobacteria).
Q43510353	Leishmania plasma membrane Mg2+-ATPase is a H+/K+-antiporter involved in glucose symport. Studies with sealed ghosts and vesicles of opposite polarity
Q36292016	Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion.
Q52800048	Links between Osmoregulation and Nitrogen-Excretion in Insects and Crustaceans.
Q33620738	Lipid and cationic polymer based transduction of botulinum holotoxin, or toxin protease alone, extends the target cell range and improves the efficiency of intoxication
Q24680571	Listeria monocytogenes exploits normal host cell processes to spread from cell to cell
Q41487914	Live-cell Microscopy and Fluorescence-based Measurement of Luminal pH in Intracellular Organelles
Q36234982	Localization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells
Q34273258	Localized Reactive Oxygen and Nitrogen Intermediates Inhibit Escape ofListeria monocytogenesfrom Vacuoles in Activated Macrophages
Q34020776	Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction.
Q73783915	Luminal arginine vasopressin stimulates Na(+)-H+ exchange and H(+)-ATPase in cortical distal tubule via V1 receptor
Q35652092	Luminal flow modulates H+-ATPase activity in the cortical collecting duct (CCD).
Q33637795	Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMP
Q48121086	Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes.
Q36717186	Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
Q35703000	Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance.
Q36512760	Lysosome-targeted stress reveals increased stability of lipofuscin-containing lysosomes
Q40887042	Lyssavirus matrix protein induces apoptosis by a TRAIL-dependent mechanism involving caspase-8 activation
Q38998257	Macrolactam analogues of macrolide natural products.
Q39658366	Macrolides of the bafilomycin family produced by Streptomyces sp. CS
Q45116951	Macrophage activation by a DNA/cationic liposome complex requires endosomal acidification and TLR9-dependent and -independent pathways.
Q27976514	Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
Q36559528	Macropinocytosis-like HIV-1 internalization in macrophages is CCR5 dependent and leads to efficient but delayed degradation in endosomal compartments
Q34470955	Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins
Q43846071	Mechanism involved in phagocytosis and killing of Listeria monocytogenes by Acanthamoeba polyphaga
Q35458800	Mechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process
Q28507749	Mechanism of the facilitation of PC2 maturation by 7B2: involvement in ProPC2 transport and activation but not folding
Q45069782	Mechanisms of VEGF- and glutamate-induced inhibition of osmotic swelling of murine retinal glial (Müller) cells: indications for the involvement of vesicular glutamate release and connexin-mediated ATP release
Q36647815	Mechanisms of acid and base secretion by the airway epithelium
Q44681091	Mechanisms of caspase-independent neuronal death: energy depletion and free radical generation.
Q28379027	Mechanisms of manganese transport in rabbit erythroid cells
Q38725187	Mechanisms of modulation of brain microvascular endothelial cells function by thrombin
Q27938078	Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase
Q37365344	Metabolic acidosis stimulates H+ secretion in the rabbit outer medullary collecting duct (inner stripe) of the kidney
Q39949932	Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2
Q87720891	Metacycloprodigiosin induced cell death selectively in β-catenin-mutated tumor cells
Q46137292	Methods to investigate autophagy during starvation and regeneration in hydra
Q27692058	Methuosis: nonapoptotic cell death associated with vacuolization of macropinosome and endosome compartments
Q37593388	Microbial toxin's effect on mitochondrial survival by increasing K+ uptake
Q34573748	Microenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy
Q43195196	Mitochondrial Ca2+ activates a cation current in Aplysia bag cell neurons
Q49304282	Mitochondrial dysfunction activates lysosomal-dependent mitophagy selectively in cancer cells
Q33697866	MnSOD upregulation induces autophagic programmed cell death in senescent keratinocytes
Q42104901	Mobilization of Ca2+ by thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone in permeabilized insulin-secreting RINm5F cells: evidence for separate uptake and release compartments in inositol 1,4,5-trisphosphate-sensitive Ca2+ pool
Q91793432	Mode-of-action analysis of the effects induced by nicotine in the in vitro micronucleus assay
Q54295700	Modification of bafilomycin structure to efficiently synthesize solid-state NMR probes that selectively bind to vacuolar-type ATPase.
Q34314053	Modification of membrane permeability by animal viruses.
Q28211647	Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CAL
Q44087120	Modulation of proton pumping across proteoliposome membranes reconstituted with tonoplast H(+)-ATPase from cultured rice (Oryza sativa L. var. Boro) cells by acyl steryl glucoside and steryl glucoside
Q42944165	Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO.
Q42992153	Molecular aspects of the endocytic pathway
Q37944859	Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease
Q48391505	Monensin‐sensitive cellular events modulate neurite extension on laminin: An example of higher‐order regulation of cell motility
Q40292963	Mouse polyomavirus enters early endosomes, requires their acidic pH for productive infection, and meets transferrin cargo in Rab11-positive endosomes.
Q37639380	Multiple A2E treatments lead to melanization of rod outer segment-challenged ARPE-19 cells
Q32052826	Multiple modulation pathways of calcium channel activity by a beta subunit. Direct evidence of beta subunit participation in membrane trafficking of the alpha1C subunit
Q27933436	Multiple polyamine transport systems on the vacuolar membrane in yeast
Q77747831	Mutational analysis of aspartate residues in the transmembrane regions and cytoplasmic loops of rat vesicular acetylcholine transporter
Q38294393	Mutations in subunit C of the vacuolar ATPase confer resistance to bafilomycin and identify a conserved antibiotic binding site
Q41928273	Mutations of pma-1, the gene encoding the plasma membrane H+-ATPase of Neurospora crassa, suppress inhibition of growth by concanamycin A, a specific inhibitor of vacuolar ATPases
Q39723487	Myxoma and vaccinia viruses exploit different mechanisms to enter and infect human cancer cells.
Q37635358	NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa
Q50700993	NAADP controls cross-talk between distinct Ca2+ stores in the heart.
Q42917771	NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors
Q37298467	NAADP receptors mediate calcium signaling stimulated by endothelin-1 and norepinephrine in renal afferent arterioles
Q36033195	NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes
Q54241856	NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages.
Q74315946	NH4+ as a substrate for apical and basolateral Na(+)-H+ exchangers of thick ascending limbs of rat kidney: evidence from isolated membranes
Q41223543	NH4Cl-induced hypertrophy is mediated by weak base effects and is independent of cell cycle processes.
Q47113074	Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity
Q41076731	Nature and control of chloride transport in insect absorptive epithelia
Q24655380	Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane
Q43691911	Neutralization of pH in the Golgi apparatus causes redistribution of glycosyltransferases and changes in the O-glycosylation of mucins.
Q24814618	Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells.
Q38518488	New cytotoxic bafilomycin C1-amide produced by Kitasatospora cheerisanensis.
Q41920840	New insight into the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium, a new type of antimalarial.
Q28295380	New insights into roles of acidocalcisomes and contractile vacuole complex in osmoregulation in protists
Q36697460	New resorption assay with mouse osteoclast-like multinucleated cells formed in vitro
Q64086128	Niclosamide Triggers Non-Canonical LC3 Lipidation
Q36230597	Nitric oxide derived from L-arginine impairs cytoplasmic pH regulation by vacuolar-type H+ ATPases in peritoneal macrophages
Q43787326	Nitrophenylphosphate as a tool to characterize gill Na(+), K(+)-ATPase activity in hyperregulating Crustacea.
Q40535263	Non-P-glycoprotein multidrug resistance in cell lines which are defective in the cellular accumulation of drug
Q40973289	Non-transferrin-bound iron uptake in Belgrade and normal rat erythroid cells
Q44028787	Norepinephrine triggers Ca2+-dependent exocytosis of 5-hydroxytryptamine from rat pinealocytes in culture
Q40051547	Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments
Q42811827	Octaarginine- and octalysine-modified nanoparticles have different modes of endosomal escape.
Q48727541	Optogenetic activation of LiGluR-expressing astrocytes evokes anion channel-mediated glutamate release.
Q28079130	Optogenetic and Chemogenetic Approaches for Studying Astrocytes and Gliotransmitters
Q42035980	Organization and characterization of a biosynthetic gene cluster for bafilomycin from Streptomyces griseus DSM 2608.
Q38203222	Osmoregulation and excretion
Q38289071	Osteoblastic Lrp4 promotes osteoclastogenesis by regulating ATP release and adenosine-A2AR signaling.
Q38384916	Our research on proton pumping ATPases over three decades: their biochemistry, molecular biology and cell biology
Q39150052	Overcoming endosomal barrier by amphotericin B-loaded dual pH-responsive PDMA-b-PDPA micelleplexes for siRNA delivery.
Q43658321	Overproduction of a functional A1 ATPase from the archaeon Methanosarcina mazei Gö1 in Escherichia coli
Q34104922	Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death.
Q34721240	Oxidized ATP protection against anthrax lethal toxin
Q72150653	Oxygen exchange reactions catalyzed by vacuolar H(+)-translocating pyrophosphatase. Evidence for reversible formation of enzyme-bound pyrophosphate
Q36551305	PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease.
Q105006036	PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity.
Q24307987	Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing
Q34187267	Papillomaviruses infect cells via a clathrin-dependent pathway
Q44402045	Partial purification and characterization of the vacuolar H(+)-ATPase of mammalian synaptic vesicles
Q52537129	Patch clamp studies on V-type ATPase of vacuolar membrane of haploid Saccharomyces cerevisiae. Preparation and utilization of a giant cell containing a giant vacuole.
Q40420991	Peroxisomes as novel players in cell calcium homeostasis
Q35023172	Persistent inhibition of ABL tyrosine kinase causes enhanced apoptotic response to TRAIL and disrupts the pro-apoptotic effect of chloroquine
Q39714351	Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages.
Q46846250	Phagocytosis-induced apoptosis of macrophages is linked to uptake, killing and degradation of bacteria
Q58211887	Phagosomal Maturation, Acidification, and Inhibition of Bacterial Growth in Nonphagocytic Cells Transfected with FcγRIIA Receptors
Q39517446	Phagosome acidification has opposite effects on intracellular survival of Bordetella pertussis and B. bronchiseptica
Q33694769	Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells.
Q44239905	Physiological and morphological evidences for the presence acidocalcisomes in Trypanosoma evansi: single cell fluorescence and 31P NMR studies
Q40398238	Picornavirus inhibitors
Q37023814	Plasmalemmal vacuolar H+-ATPases in angiogenesis, diabetes and cancer
Q36362439	Pleiotropic control of secondary metabolism and morphological development by KsbC, a butyrolactone autoregulator receptor homologue in Kitasatospora setae
Q64260067	Pma1p Contributes to Growth, pH Homeostasis, and Hyphal Formation
Q44297173	Polyamine transport, accumulation, and release in brain.
Q40810570	Polyethylenimine-mediated gene delivery: a mechanistic study
Q31010609	Polyimidazole conjugated oligonucleotides reach the nucleus of HeLa cells.
Q41926356	Porcine submaxillary mucin forms disulfide-linked multimers through its amino-terminal D-domains
Q80478071	Possible involvement of hyphal phosphatase in phosphate efflux from intraradical hyphae isolated from mycorrhizal roots colonized by Gigaspora margarita
Q35815729	Postsynaptic VAMP/Synaptobrevin Facilitates Differential Vesicle Trafficking of GluA1 and GluA2 AMPA Receptor Subunits
Q42629820	Potassium depletion increases proton pump (H(+)-ATPase) activity in intercalated cells of cortical collecting duct
Q73731997	Potential role of vacuolar H-adenosine triphosphatase in neointimal formation in cultured human saphenous vein
Q59177961	Preparation of Plasma Membrane Vesicles from Black Spruce and Jack Pine Roots
Q42183824	Probing the endocytic pathways of the filamentous bacteriophage in live cells using ratiometric pH fluorescent indicator
Q42139486	Processing and trafficking of a prohormone convertase 2 active site mutant
Q42159115	Prodigiosins uncouple lysosomal vacuolar-type ATPase through promotion of H+/Cl- symport
Q38741538	Production of macrolide antibiotics from a cytotoxic soil Streptomyces sp. strain ZDB.
Q41081503	Productive penetration of rotavirus in cultured cells induces coentry of the translation inhibitor alpha-sarcin
Q92883445	Progeny Varicella-Zoster Virus Capsids Exit the Nucleus but Never Undergo Secondary Envelopment during Autophagic Flux Inhibition by Bafilomycin A1
Q47962047	Properties and molecular cloning of Ca2+/H+ antiporter in the vacuolar membrane of mung bean
Q37406074	Protective actions of the vesicular monoamine transporter 2 (VMAT2) in monoaminergic neurons
Q37635848	Protein kinase C activates an H+ (equivalent) conductance in the plasma membrane of human neutrophils
Q28612038	Proteolysis and antigen presentation by MHC class II molecules
Q48619578	Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology
Q24795540	Proteolytic cleavage of pertussis toxin S1 subunit is not essential for its activity in mammalian cells
Q34682192	Proteomic analysis of the acidocalcisome, an organelle conserved from bacteria to human cells
Q83273262	Proton Transport Activity of the Purified Vacuolar H-ATPase from Oats : Direct Stimulation by Cl
Q38684254	Proton Transport and pH Control in Fungi
Q79855311	Proton modulation of ion channels in isolated horizontal cells of the goldfish retina
Q30837316	Proton pumping accompanies calcification in foraminifera
Q50795795	Proton transport mechanism in the cell membrane of Xenopus laevis oocytes
Q74516086	Proton-ATPase activities involved in the uptake of an S-adenosylmethionine analogue
Q46274294	Protoparvovirus Cell Entry.
Q33971830	Pumping ions: rapid parallel evolution of ionic regulation following habitat invasions
Q45041227	Rapamycin induces of protective autophagy in vascular endothelial cells exposed to oxygen-glucose deprivation
Q100521473	Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain
Q42978427	Reactive and bioactive cationic α-helical polypeptide template for nonviral gene delivery
Q47732958	Reappearance of hydrolytic activities and tonoplast proteins in the regenerated vacuole of evacuolated protoplasts
Q40132929	Receptor Priming of Major Group Human Rhinoviruses for Uncoating and Entry at Mild Low-pH Environments
Q36047074	Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment
Q34142939	Receptor-mediated entry by equine infectious anemia virus utilizes a pH-dependent endocytic pathway
Q35127561	Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification
Q38347408	Recycling, degradation and sensitivity to the synergistic anion of transferrin in the receptor-independent route of iron uptake by human hepatoma (HuH-7) cells
Q40967431	Reduced capacitative calcium entry correlates with vesicle accumulation and apoptosis
Q43757171	Reduction of quantal size and inhibition of neuromuscular transmission by bafilomycin A.
Q61943159	Regeneration of a Lytic Central Vacuole and of Neutral Peripheral Vacuoles Can Be Visualized by Green Fluorescent Proteins Targeted to Either Type of Vacuoles
Q37408504	Regulation of apoptosis and innate immune stimuli in inflammation-induced preterm labor
Q35272942	Regulation of chlamydial infection by host autophagy and vacuolar ATPase-bearing organelles.
Q41390709	Regulation of intracellular pH in J774 murine macrophage cells: H+ extrusion processes
Q42239490	Regulation of membrane-type 1 matrix metalloproteinase activity by vacuolar H+-ATPases
Q35107596	Regulation of purinergic signaling in biliary epithelial cells by exocytosis of SLC17A9-dependent ATP-enriched vesicles
Q44666427	Regulation of tyrosinase processing and trafficking by organellar pH and by proteasome activity
Q36931418	Regulation of vacuolar pH and its modulation by some microbial species
Q34447935	Release of ATP from marginal cells in the cochlea of neonatal rats can be induced by changes in extracellular and intracellular ion concentrations
Q28349783	Release of amines from acidified stores following accumulation by Transport-P
Q71816621	Release of noradrenaline from isolated rat tail artery induced by bafilomycin A1
Q30539701	Renal intercalated cells are rather energized by a proton than a sodium pump
Q34350645	Renal vacuolar H+-ATPase
Q39869648	Requirement for vacuolar proton-ATPase activity during entry of influenza virus into cells
Q34253333	Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion.
Q48552373	Rethinking the Combination of Proton Exchanger Inhibitors in Cancer Therapy
Q36937813	Retrograde transport from the pre-Golgi intermediate compartment and the Golgi complex is affected by the vacuolar H+-ATPase inhibitor bafilomycin A1.
Q36469011	Retrovirus entry by endocytosis and cathepsin proteases
Q36021212	Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway.
Q95432362	Reversibility of H+-ATPase and H+-pyrophosphatase in tonoplast vesicles from maize coleoptiles and seeds
Q33781665	Reversible association between the V1 and V0 domains of yeast vacuolar H+-ATPase is an unconventional glucose-induced effect
Q34296031	Rhesus rhadinovirus infection of rhesus fibroblasts occurs through clathrin-mediated endocytosis
Q40678543	Role for a P-type H+-ATPase in the acidification of the endocytic pathway of Trypanosoma cruzi.
Q41925628	Role for the plasmodium falciparum digestive vacuole in chloroquine resistance
Q45150137	Role of H+-ATPase-mediated acidification in sorting and release of the regulated secretory protein chromogranin A: evidence for a vesiculogenic function
Q42048523	Role of macrophage scavenger receptors in response to Listeria monocytogenes infection in mice
Q35160411	Role of pH in a nitric oxide-dependent increase in cytosolic Cl- in retinal amacrine cells
Q33927836	Role of pH in tumor-trapping of the anticancer drug 5-fluorouracil
Q48137567	Role of synaptic vesicle proton gradient and protein phosphorylation on ATP-mediated activation of membrane-associated brain glutamate decarboxylase
Q56396086	Role of the vacuolar ATPase in the replication cycle
Q33938004	Role of vacuolar ATPase in the trafficking of renal type IIa sodium-phosphate cotransporter.
Q27933484	Role of vacuolar acidification in protein sorting and zymogen activation: a genetic analysis of the yeast vacuolar proton-translocating ATPase
Q72134510	Role of vacuolar adenosine triphosphatase in the regulation of cytosolic pH in hepatocytes
Q36479718	Rotenone inhibits autophagic flux prior to inducing cell death.
Q42501171	Rubidium reduces potassium permeability and fluid secretion in Malpighian tubules of Locusta migratoria, L.
Q40551623	S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients
Q52537667	SNARE protein-dependent glutamate release from astrocytes.
Q34752168	STIM1 and STIM2 are located in the acidic Ca2+ stores and associates with Orai1 upon depletion of the acidic stores in human platelets
Q44785422	Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1.
Q36660048	Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells
Q30480354	Salmonella trafficking is defined by continuous dynamic interactions with the endolysosomal system.
Q81391389	Salt stress in Thellungiella halophila activates Na+ transport mechanisms required for salinity tolerance
Q90436782	Schnyder Corneal Dystrophy-Associated UBIAD1 is Defective in MK-4 Synthesis and Resists Autophagy-Mediated Degradation
Q35040033	Secretion of L-glutamate from osteoclasts through transcytosis.
Q36324064	Selective internalization of sodium channels in rat dorsal root ganglion neurons infected with herpes simplex virus-1
Q34722924	Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis.
Q31027669	Sensing and adaptation to low pH mediated by inducible amino acid decarboxylases in Salmonella
Q37101293	Sensitivity to vanadate and isoforms of subunits A and B distinguish the osteoclast proton pump from other vacuolar H+ ATPases
Q51075537	Separate Ca2+ sources are buffered by distinct Ca2+ handling systems in aplysia neuroendocrine cells.
Q41226753	Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease
Q42595034	Silk-Based Gene Carriers with Cell Membrane Destabilizing Peptides
Q72192983	Simultaneous isolation and biochemical characterization of connecting and collecting tubules by ficoll gradient
Q27935796	Site-directed mutagenesis of the 100-kDa subunit (Vph1p) of the yeast vacuolar (H+)-ATPase
Q37714909	Small molecules for bone diseases
Q40128897	Small-molecule screening identifies modulators of aquaporin-2 trafficking.
Q42981661	Sodium-proton exchange stimulates Ca2+ release from acidocalcisomes of Trypanosoma brucei
Q41870990	Soluble form of complement C3b/C4b receptor (CR1) results from a proteolytic cleavage in the C-terminal region of CR1 transmembrane domain
Q52374319	Some assembly required: Contributions of Tom Stevens' lab to the V-ATPase field.
Q35139299	Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host
Q30631709	Stable expression of protective protein/cathepsin A-green fluorescent protein fusion genes in a fibroblastic cell line from a galactosialidosis patient. Model system for revealing the intracellular transport of normal and mutated lysosomal enzymes
Q80149584	Sterically stabilized ph-sensitive liposomes
Q41096025	Stress protein (hsp73)-mediated, TAP-independent processing of endogenous, truncated SV40 large T antigen for Db-restricted peptide presentation
Q92614212	Structural comparison of the vacuolar and Golgi V-ATPases from Saccharomyces cerevisiae
Q35384447	Structural conservation and functional diversity of V-ATPases
Q35185933	Structure and Properties of the Coated Vesicle Proton Pump
Q35384331	Structure and properties of the coated vesicle (H+)-ATPase
Q27937111	Structure and properties of the vacuolar (H+)-ATPases
Q33881725	Structure, function and regulation of the plant vacuolar H(+)-translocating ATPase
Q77746225	Structure, function and regulation of the vacuolar (H+)-ATPases
Q38260405	Structure, molecular genetics, and evolution of vacuolar H+-ATPases
Q36647895	Structure-based organic synthesis of drug prototypes: a personal odyssey
Q70990124	Studies on the mechanism of swelling-induced lysosomal alkalinization in vascular smooth muscle cells
Q42825339	Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport
Q67494274	Substrate-induced modulation of ATP turnover in dog and rabbit proximal tubules
Q47917223	Subunit Composition and Organization of the Vacuolar H-ATPase from Oat Roots
Q46745788	Subunit a of the yeast V-ATPase participates in binding of bafilomycin
Q28541701	Suppressing dengue-2 infection by chemical inhibition of Aedes aegypti host factors
Q35115803	Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1.
Q36692413	Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons
Q37137079	Synaptic vesicle-bound pyruvate kinase can support vesicular glutamate uptake
Q28343929	Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans
Q39281821	Synthesis and biological evaluation of a potent salicylihalamide A lactam analogue.
Q38163949	Synthesis of cytotoxic palmerolides
Q40652342	Synthesis of photoactivable inhibitors of osteoclast vacuolar ATPase
Q34973666	Synthetic histidine-rich peptides inhibit Candida species and other fungi in vitro: role of endocytosis and treatment implications
Q42831593	TAN-1323 C and D, new concanamycin-group antibiotics; detection of the angiostatic activity with a wide range of macrolide antibiotics
Q35646047	TNF-α Induced by Hepatitis C Virus via TLR7 and TLR8 in Hepatocytes Supports Interferon Signaling via an Autocrine Mechanism
Q35972458	TOR-induced resistance to toxic adenosine analogs in Leishmania brought about by the internalization and degradation of the adenosine permease
Q52631856	TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons.
Q36694073	TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction.
Q39849413	TRPM2 functions as a lysosomal Ca2+-release channel in beta cells
Q38358020	Target cell-specific DNA transfer mediated by a chimeric multidomain protein. Novel non-viral gene delivery system
Q30525356	Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis
Q52025256	Tetanic stimulation recruits vesicles from reserve pool via a cAMP-mediated process in Drosophila synapses.
Q27478473	The E5 oncoprotein of human papillomavirus type 16 inhibits the acidification of endosomes in human keratinocytes
Q60119507	The Effect of Moulting and Sodium Depletion on Sodium Transport and the Activities of Na+K+-ATPase, and V-ATPase in the Freshwater Crayfish Cherax destructor (Crustacea: Parastacidae)
Q34983654	The Erv41-Erv46 complex serves as a retrograde receptor to retrieve escaped ER proteins
Q42807820	The HPV-16 E5 oncogene and bafilomycin A(1) influence cell motility
Q40833610	The HPV16 E5 oncogene inhibits endocytic trafficking
Q36944562	The Histoplasma capsulatum vacuolar ATPase is required for iron homeostasis, intracellular replication in macrophages and virulence in a murine model of histoplasmosis
Q26765437	The Ins and Outs of Anthrax Toxin
Q28510158	The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis
Q34464231	The PHD/LAP-domain protein M153R of myxomavirus is a ubiquitin ligase that induces the rapid internalization and lysosomal destruction of CD4
Q33770926	The PLC/IP 3 R/PKC pathway is required for ethanol-enhanced GABA release.
Q59328893	The Trans Golgi Region is a Labile Intracellular Ca Store Sensitive to Emetine
Q24298252	The a-subunit of the V-type H+-ATPase interacts with phosphofructokinase-1 in humans
Q53992214	The absence of stereoselective P-glycoprotein- and multidrug resistance-associated protein-mediated transport of daunorubicin.
Q73695358	The antineoplastic drug lonidamine interferes with the acidification mechanism of cell organelles
Q44456159	The bafilomycin/concanamycin binding site in subunit c of the V-ATPases from Neurospora crassa and Saccharomyces cerevisiae
Q42012323	The binding site of the V-ATPase inhibitor apicularen is in the vicinity of those for bafilomycin and archazolid.
Q40997484	The cellular basis of metabolic alkalosis
Q41829565	The chondroitin sulfate form of invariant chain trimerizes with conventional invariant chain and these complexes are rapidly transported from the trans-Golgi network to the cell surface
Q41606448	The colon carcinoma cell line Caco-2 contains an H+/K(+)-ATPase that contributes to intracellular pH regulation
Q39577308	The coronavirus transmissible gastroenteritis virus causes infection after receptor-mediated endocytosis and acid-dependent fusion with an intracellular compartment
Q46334128	The diversity and antibiotic properties of actinobacteria associated with endemic deepwater amphipods of Lake Baikal.
Q78033435	The effect of Mg2+, nucleotides and ATPase inhibitors on the uptake of [3H]-cGMP to inside-out vesicles from human erythrocytes
Q57717462	The effect of acute metabolic alkalosis on bicarbonate transport along the loop of Henle. The role of active transport processes and passive paracellular backflux
Q39873180	The entry of reovirus into L cells is dependent on vacuolar proton-ATPase activity
Q24634743	The fungal vacuole: composition, function, and biogenesis
Q34178284	The human papillomavirus type 16 E5 oncoprotein inhibits epidermal growth factor trafficking independently of endosome acidification
Q30513403	The induction of autophagy by mechanical stress.
Q35592082	The insect plasma membrane H+ V-ATPase: intra-, inter-, and supramolecular aspects
Q44086480	The internal pH of synaptic-like microvesicles in rat pinealocytes in culture
Q48292816	The pH-sensitive dye acridine orange as a tool to monitor exocytosis/endocytosis in synaptosomes
Q38672395	The packing density of a supramolecular membrane protein cluster is controlled by cytoplasmic interactions.
Q71825204	The pegs on the decorated tubules of the contractile vacuole complex of Paramecium are proton pumps
Q35185943	The plasma membrane ATPase of archaebacteria. A chimeric energy converter
Q27937461	The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae
Q46794715	The relative contribution of mannose salvage pathways to glycosylation in PMI-deficient mouse embryonic fibroblast cells
Q35922601	The role of CD38 in Fcγ receptor (FcγR)-mediated phagocytosis in murine macrophages
Q37123177	The role of E3 in pH protection during alphavirus assembly and exit
Q42123116	The role of a H(+)-ATPase in the regulation of cytoplasmic pH in Trypanosoma cruzi epimastigotes
Q73194808	The role of vacuolar malate-transport capacity in crassulacean acid metabolism and nitrate nutrition. Higher malate-transport capacity in ice plant after crassulacean acid metabolism-induction and in tobacco under nitrate nutrition
Q36863973	The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles
Q36695464	The taming of the cell penetrating domain of the HIV Tat: myths and realities
Q64077911	The tricyclic antidepressant clomipramine inhibits neuronal autophagic flux
Q28585336	The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores
Q41076100	The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.
Q92839152	The use of green fluorescent protein-tagged virus-like particles as a tracer in the early phase of chikungunya infection
Q35384366	The vacuolar ATPase of Neurospora crassa
Q41359135	The vacuolar H(+)-ATPase inhibitor bafilomycin A1 differentially affects proteolytic processing of mutant and wild-type beta-amyloid precursor protein
Q24530182	The vacuolar H+-ATPase: a universal proton pump of eukaryotes
Q24293671	The vacuolar-ATPase inhibitor bafilomycin and mutant VPS35 inhibit canonical Wnt signaling
Q37266848	The yeast lysosome-like vacuole: endpoint and crossroads
Q59488014	Tolbutamide stimulates exocytosis of glucagon by inhibition of a mitochondrial-like ATP-sensitive K+ (KATP) conductance in rat pancreatic A-cells
Q43031196	Tonoplast Na+/H+ Antiport Activity and Its Energization by the Vacuolar H+-ATPase in the Halophytic Plant Mesembryanthemum crystallinum L.
Q40519775	Trafficking of exogenous peptides into proteasome-dependent major histocompatibility complex class I pathway following enterotoxin B subunit-mediated delivery
Q43944914	Transcytosis of iota-toxin across polarized CaCo-2 cells
Q28610251	Transfer of free polymannose-type oligosaccharides from the cytosol to lysosomes in cultured human hepatocellular carcinoma HepG2 cells
Q35650838	Transferrin receptor 2: evidence for ligand-induced stabilization and redirection to a recycling pathway
Q41317185	Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump.
Q74790018	Transport of Ascorbic and Dehydroascorbic Acids across Protoplast and Vacuole Membranes Isolated from Barley (Hordeum vulgare L. cv Gerbel) Leaves
Q74121193	Transport of lucifer yellow CH into plant vacuoles--evidence for direct energization of a sulphonated substance and implications for the design of new molecular probes
Q36372323	Triple-Layered pH-Responsive Micelleplexes Loaded with siRNA and Cisplatin Prodrug for NF-Kappa B Targeted Treatment of Metastatic Breast Cancer
Q57976335	Two Mechanisms of Synaptic Vesicle Recycling in Rat Brain Nerve Terminals
Q35872288	Two-Pore Channel 2 activity is required for slow muscle cell-generated Ca(2+) signaling during myogenesis in intact zebrafish.
Q40040947	Uncoating of human rhinovirus serotype 2 from late endosomes
Q46207582	Unconventional secretion of FABP4 by endosomes and secretory lysosomes.
Q31120131	Undecylprodigiosin induced apoptosis in P388 cancer cells is associated with its binding to ribosome
Q38913294	Uptake of clostridium botulinum C3 exoenzyme into intact HT22 and J774A.1 cells
Q86639087	Uptake of the fluorescent indicator atebrin into acidic vacuoles in the halotolerant alga Dunaliella satina
Q37724223	Urotensin II promotes vagal-mediated bradycardia by activating cardiac-projecting parasympathetic neurons of nucleus ambiguus
Q35853210	V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation
Q43526617	V-ATPase dysfunction suppresses polyphosphate synthesis in Saccharomyces cerevisiae.
Q39069422	V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activation in vivo
Q36476071	V-ATPases as drug targets
Q43984455	V-type H+-ATPase in the human eccrine sweat duct: immunolocalization and functional demonstration
Q41935351	Vacuolar ATPase inactivation blocks recycling to the trans-Golgi network from the plasma membrane.
Q67898943	Vacuolar Acidification and Bafilomycin-Sensitive Proton Translocating ATPase in Human Epidermal Langerhans Cells
Q42859055	Vacuolar H(+)-ATPase of adrenal secretory granules. Rapid partial purification and reconstitution into proteoliposomes
Q41666245	Vacuolar H(+)-ATPases. Targets for drug discovery?
Q35727795	Vacuolar H(+)-pumping ATPase variable transport coupling ratio controlled by pH.
Q35384391	Vacuolar H(+)-translocating ATPases from plants: structure, function, and isoforms
Q71875410	Vacuolar H(+)-translocating pyrophosphatase is induced by anoxia or chilling in seedlings of rice
Q59072675	Vacuolar H+-ATPase: An Essential Multitasking Enzyme in Physiology and Pathophysiology
Q92915796	Vacuolar H+-ATPases (V-ATPases) as therapeutic targets: a brief review and recent developments
Q36761876	Vacuolar and plasma membrane proton pumps collaborate to achieve cytosolic pH homeostasis in yeast
Q61811397	Vacuolar proton-translocating ATPase is required for antifungal resistance and virulence of Candida glabrata
Q32109561	Vacuolar-type H+-ATPase regulates cytoplasmic pH in Toxoplasma gondii tachyzoites
Q37194511	Vacuolar-type proton pumps in insect epithelia
Q50605863	Vacuole dynamics in the salivary glands of Drosophila melanogaster during prepupal development.
Q36669880	Vesicle trafficking and recycling at the neuromuscular junction: two pathways for endocytosis
Q39648002	Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1.
Q44804042	Vesicular glutamate transporter-dependent glutamate release from astrocytes.
Q39375097	Vesicular nucleotide transporter (VNUT): appearance of an actress on the stage of purinergic signaling
Q81241755	Vesicular release of glutamate from hippocampal neurons in culture: an immunocytochemical assay
Q50461676	Vestibular hair bundles control pH with (Na+, K+)/H+ exchangers NHE6 and NHE9.
Q24299858	Virus entry. Lassa virus entry requires a trigger-induced receptor switch
Q38042428	Virus infection-induced bronchial asthma exacerbation
Q41948748	Virus-mediated release of endosomal content in vitro: different behavior of adenovirus and rhinovirus serotype 2
Q47073663	Visualization in zebrafish larvae of Na(+) uptake in mitochondria-rich cells whose differentiation is dependent on foxi3a
Q28534404	Visualization of DC-SIGN-mediated entry pathway of engineered lentiviral vectors in target cells
Q35630375	Visualization of intracellular pathways of engineered baculovirus in mammalian cells
Q24646930	Visualization of targeted transduction by engineered lentiviral vectors
Q34298435	Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages
Q30156041	WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification
Q31086160	Water secretion associated with exocytosis in endocrine cells revealed by micro forcemetry and evanescent wave microscopy
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P819	ADS bibcode	1988PNAS...85.7972B
P356	DOI	10.1073/PNAS.85.21.7972
P8608	Fatcat ID	release_mpnhocexbfbtzdtpwlojthly34
P932	PMC publication ID	282335
P698	PubMed publication ID	2973058
P5875	ResearchGate publication ID	20183320

P2093	author name string	K Altendorf
		A Siebers
		E J Bowman
P2860	cites work	Protein measurement with the Folin phenol reagent	Q20900776
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		Purification of a putative K+-ATPase from Streptococcus faecalis	Q72555456
		Modification of the Neurospora crassa plasma membrane [H+]-ATPase with N,N'-dicyclohexylcarbodiimide	Q72774734
		Mechanism of the Na+, K+ pump. Protein structure and conformations of the pure (Na+ +K+)-ATPase	Q30412322
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		59 Inhibitors of the ATP synthetase systems	Q36026849
		The cDNA sequence of the 69-kDa subunit of the carrot vacuolar H+-ATPase. Homology to the beta-chain of F0F1-ATPases	Q36416078
		Identification of the dicyclohexylcarbodiimide-reactive protein component of the adenosine 5'-triphosphate energy-transducing system of Escherichia coli	Q36609039
		Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae	Q36924028
		The mitochondrial electron transport and oxidative phosphorylation system	Q39382891
		Chemical probes of the mitochondrial ATP synthesis and translocation	Q39382923
		Acidification of the endocytic and exocytic pathways	Q39459758
		H+-ATPases from mitochondria, plasma membranes, and vacuoles of fungal cells	Q39461998
		Nuclear mutations conferring oligomycin resistance in Neurospora crassa	Q39856000
		An automated continuous assay of membrane-bound and soluble ATPases and related enzymes	Q39993384
		The Proton-Translocating Pumps of Oxidative Phosphorylation	Q40098476
		Polymorphism and conformational dynamics of F1-ATPases from bacterial membranes a model for the regulation of these enzymes on the basis of molecular plasticity	Q40103642
		Structure and function of proton-translocating adenosine triphosphatase (F0F1): biochemical and molecular biological approaches	Q40115807
		Plasma membrane ATPase of fungi and plants as a novel type of proton pump	Q40142202
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		Isolation of ATPase I, the proton pump of chromaffin-granule membranes	Q42064873
		A simple technique for eliminating interference by detergents in the Lowry method of protein determination	Q43517303
		Partial purification of a tonoplast ATPase from corn coleoptiles	Q44543530
		Purification and characterization of (Na+ plus K+ )-ATPase. 3. Purification from the outer medulla of mammalian kidney after selective removal of membrane components by sodium dodecylsulphate	Q45249662
		Size of the plasma membrane H+-ATPase from Neurospora crassa determined by radiation inactivation and comparison with the sarcoplasmic reticulum Ca2+-ATPase from skeletal muscle.	Q47222452
		Subunit composition and ATP site labeling of the coated vesicle proton-translocating adenosinetriphosphatase	Q48193686
		Isolation and reconstitution of the clathrin-coated vesicle proton translocating complex	Q48376496
		Discovery, production and purification of the Na+, K+ activated ATPase inhibitor, L-681,110 from the fermentation broth of Streptomyces sp. MA-5038.	Q48631687
		On the mechanism of Na+- and K+-stimulated hydrolysis of adenosine triphosphate. 1. Purification and properties of a Na+-and K+-activated ATPase from ox brain.	Q51214480
		Inhibition of the plasma membrane [H+]-ATPase of Neurospora crassa by N-ethylmaleimide. Protection by nucleotides	Q62993034
		Purification and characterization of the plasma membrane ATPase of Neurospora crassa	Q62993075
		Formation of a beta-aspartyl phosphate intermediate by the vanadate-sensitive ATPase of Streptococcus faecalis	Q67274229
		Similarities and differences between the tonoplast-type and the mitochondrial H+-ATPases of oat roots	Q69868472
		The purified ATPase from chromaffin granule membranes is an anion-dependent proton pump	Q69901288
		Isolation and reconstitution of the dicyclohexylcarbodiimide-sensitive proton pore of the clathrin-coated vesicle proton translocating complex	Q69907804
		Purification of vacuolar membranes, mitochondria, and plasma membranes from Neurospora crassa and modes of discriminating among the different H+-ATPases	Q69930665
		Proton-conducting portion (F0) from Escherichia coli ATP synthase: preparation, dissociation into subunits, and reconstitution of an active complex	Q69933155
		Preparation and reconstitution of F1F0 and F0 from Escherichia coli	Q69933157
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		K+-ATPase from Escherichia coli: isolation and characterization	Q70069901
P433	issue	21
P407	language of work or name	English	Q1860
P304	page(s)	7972-7976
P577	publication date	1988-11-01
P1433	published in	Proceedings of the National Academy of Sciences of the United States of America	Q1146531
P1476	title	Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells
P478	volume	85

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells

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