Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion

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Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.80.2.710-722.2006
P932PMC publication ID1346879
P698PubMed publication ID16378974

P50authorMichael A. JarvisQ42424922
P2093author name stringJay A Nelson
David C Johnson
Michael A Jarvis
Derek D Drummond
Brent J Ryckman
P2860cites workConstruction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deletedQ24655638
Roles for Endocytosis and Low pH in Herpes Simplex Virus Entry into HeLa and Chinese Hamster Ovary CellsQ24679497
On the entry of Semliki forest virus into BHK-21 cellsQ27482326
An efficient recombination system for chromosome engineering in Escherichia coliQ29615038
Role of glycoprotein B of herpes simplex virus type 1 in viral entry and cell fusionQ36877928
Human cytomegalovirus induces monocyte differentiation and migration as a strategy for dissemination and persistenceQ37422612
Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteomeQ37568012
Cellular integrins function as entry receptors for human cytomegalovirus via a highly conserved disintegrin-like domainQ37593516
Mutations in herpes simplex virus glycoprotein D distinguish entry of free virus from cell-cell spreadQ39593535
Human cytomegalovirus infection of caco-2 cells occurs at the basolateral membrane and is differentiation state dependentQ39593923
Herpes simplex virus gE/gI sorts nascent virions to epithelial cell junctions, promoting virus spreadQ39601524
Requirement for vacuolar proton-ATPase activity during entry of influenza virus into cellsQ39869648
Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains.Q39872953
Human cytomegalovirus UL131-128 genes are indispensable for virus growth in endothelial cells and virus transfer to leukocytesQ39960937
Pseudorabies virus glycoproteins gII and gp50 are essential for virus penetrationQ40107079
Infectious cell entry mechanism of influenza virus.Q40141916
Alternate replication in B cells and epithelial cells switches tropism of Epstein-Barr virusQ40727982
Cell types involved in replication and distribution of human cytomegalovirus.Q40958077
Human cytomegalovirus penetrates host cells by pH-independent fusion at the cell surfaceQ41597223
Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropismQ41839444
Entry of human cytomegalovirus into retinal pigment epithelial and endothelial cells by endocytosisQ41923033
Penetration of cells by herpes simplex virus does not require a low pH-dependent endocytic pathwayQ41942419
Pathway of vesicular stomatitis virus entry leading to infectionQ43674816
Initiation of human cytomegalovirus infection requires initial interaction with cell surface heparan sulfateQ46056201
Clinical failure of CMV retinitis with intravitreal cidofovir is associated with antiviral resistanceQ46657547
Genetic content of wild-type human cytomegalovirusQ47709383
Rescue of human cytomegalovirus strain AD169 tropism for both leukocytes and human endothelial cellsQ57275307
Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomyQ71210092
Tropism of human cytomegalovirus for endothelial cells is determined by a post-entry step dependent on efficient translocation to the nucleusQ73209433
Nuclear import as a barrier to infection of human umbilical vein endothelial cells by human cytomegalovirus strain AD169Q77447839
Human cytomegalovirus as a direct pathogen: correlation of multiorgan involvement and cell distribution with clinical and pathological findings in a case of congenital inclusion diseaseQ78052127
A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNAQ29615197
Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cellsQ33661004
Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1.Q33788855
Human cytomegalovirus cell-to-cell spread in the absence of an essential assembly proteinQ33837853
Herpes simplex virus type 1 enters human epidermal keratinocytes, but not neurons, via a pH-dependent endocytic pathwayQ33843108
Human cytomegalovirus UL130 protein promotes endothelial cell infection through a producer cell modification of the virion.Q33843302
Poly(ethylene glycol) (PEG)-mediated fusion between pure lipid bilayers: a mechanism in common with viral fusion and secretory vesicle release?Q33892321
Deletion of gpUL132, a structural component of human cytomegalovirus, results in impaired virus replication in fibroblastsQ33987451
A review of genetic differences between limited and extensively passaged human cytomegalovirus strainsQ34263661
Directed egress of animal viruses promotes cell-to-cell spreadQ34327423
Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entryQ34344174
The human cytomegalovirus ribonucleotide reductase homolog UL45 is dispensable for growth in endothelial cells, as determined by a BAC-cloned clinical isolate of human cytomegalovirus with preserved wild-type characteristicsQ34345137
Human cytomegalovirus US7, US8, US9, and US10 are cytoplasmic glycoproteins, not found at cell surfaces, and US9 does not mediate cell-to-cell spread.Q34364995
Coding potential of laboratory and clinical strains of human cytomegalovirusQ34388908
Do pathogens accelerate atherosclerosis?Q34389205
Epidermal growth factor receptor is a cellular receptor for human cytomegalovirusQ34535736
Rapid genetic engineering of human cytomegalovirus by using a lambda phage linear recombination system: demonstration that pp28 (UL99) is essential for production of infectious virus.Q34553401
Human cytomegalovirus retinitis: pathogenicity, immune evasion and persistenceQ35111605
Cellular and viral requirements for rapid endocytic entry of herpes simplex virusQ35122489
The human cytomegalovirus.Q35143349
Microtubule network facilitates nuclear targeting of human cytomegalovirus capsidQ35155425
Herpesvirus entry: an updateQ35217323
Pathogenesis of human cytomegalovirus infection and cellular targetsQ35789320
Endocytosis of influenza virusesQ35862726
Integrin alphavbeta3 is a coreceptor for human cytomegalovirusQ35865693
Membrane proteins specified by herpes simplex viruses. III. Role of glycoprotein VP7(B2) in virion infectivityQ36495307
Correlation between infectivity and physical virus particles in human cytomegalovirusQ36510535
A herpes simplex virus 1 US11-expressing cell line is resistant to herpes simplex virus infection at a step in viral entry mediated by glycoprotein DQ36633169
Envelope glycoprotein gp50 of pseudorabies virus is essential for virus entry but is not required for viral spread in miceQ36639085
A mutant herpes simplex virus type 1 unable to express glycoprotein L cannot enter cells, and its particles lack glycoprotein HQ36686818
Epstein-Barr virus enters B cells and epithelial cells by different routesQ36697940
Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virusQ36825917
A herpes simplex virus mutant in which glycoprotein D sequences are replaced by beta-galactosidase sequences binds to but is unable to penetrate into cellsQ36866557
Herpes simplex viruses lacking glycoprotein D are unable to inhibit virus penetration: quantitative evidence for virus-specific cell surface receptorsQ36873841
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectCytomegalovirusQ6946
endotheliumQ111140
P304page(s)710-722
P577publication date2006-01-01
P1433published inJournal of VirologyQ1251128
P1476titleHuman cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion
P478volume80

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cites work (P2860)
Q36069719A Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig Cytomegalovirus
Q37182670A Novel Non-Replication-Competent Cytomegalovirus Capsid Mutant Vaccine Strategy Is Effective in Reducing Congenital Infection
Q40060063A comparative review of viral entry and attachment during large and giant dsDNA virus infections.
Q91675842A fifty-year odyssey: prospects for a cytomegalovirus vaccine in transplant and congenital infection
Q33648958A human cytomegalovirus gO-null mutant fails to incorporate gH/gL into the virion envelope and is unable to enter fibroblasts and epithelial and endothelial cells
Q35378089A viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism.
Q37127280An attenuated cytomegalovirus vaccine with a deletion of a viral chemokine gene is protective against congenital CMV transmission in a guinea pig model
Q36667906An endothelial cell-specific requirement for the UL133-UL138 locus of human cytomegalovirus for efficient virus maturation
Q91264520Analysis of relationships between polymorphisms in the genes encoding the pentameric complex and neutralization of clinical cytomegalovirus isolates
Q28550400Antigenic Characterization of the HCMV gH/gL/gO and Pentamer Cell Entry Complexes Reveals Binding Sites for Potently Neutralizing Human Antibodies
Q21559401BST2/Tetherin enhances entry of human cytomegalovirus
Q54217767CD147 Promotes Entry of Pentamer-Expressing Human Cytomegalovirus into Epithelial and Endothelial Cells.
Q37347325Cell Surface THY-1 Contributes to Human Cytomegalovirus Entry via a Macropinocytosis-Like Process
Q42572343Characterization of a discontinuous neutralizing epitope on glycoprotein B of human cytomegalovirus
Q45942829Characterization of the guinea pig cytomegalovirus genome locus that encodes homologs of human cytomegalovirus major immediate-early genes, UL128, and UL130.
Q36423984Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells.
Q39943786Charge cluster-to-alanine scanning of UL128 for fine tuning of the endothelial cell tropism of human cytomegalovirus
Q40067378Chemokines encoded by herpesviruses
Q63246525Chewing the Fat: The Conserved Ability of DNA Viruses to Hijack Cellular Lipid Metabolism
Q36685041Coding potential of UL/b' from the initial source of rhesus cytomegalovirus Strain 68-1.
Q37123419Comparative analysis of gO isoforms reveals that strains of human cytomegalovirus differ in the ratio of gH/gL/gO and gH/gL/UL128-131 in the virion envelope
Q37406553Congenital cytomegalovirus infection: molecular mechanisms mediating viral pathogenesis
Q37336684Contributions of herpes simplex virus 1 envelope proteins to entry by endocytosis
Q33557172Cytomegalovirus Restructures Lipid Rafts via a US28/CDC42-Mediated Pathway, Enhancing Cholesterol Efflux from Host Cells
Q40145257Cytomegalovirus UL128 homolog mutants that form a pentameric complex produce virus with impaired epithelial and trophoblast cell tropism and altered pathogenicity in the guinea pig.
Q41786108Cytomegalovirus UL131-128 products promote gB conformational transition and gB-gH interaction during entry into endothelial cells
Q37559627Cytomegalovirus and varicella-zoster virus vaccines in hematopoietic stem cell transplantation
Q27000998Cytomegalovirus antivirals and development of improved animal models
Q37252609Cytomegalovirus vaccine strain towne-derived dense bodies induce broad cellular immune responses and neutralizing antibodies that prevent infection of fibroblasts and epithelial cells
Q36517096Cytomegalovirus vaccines and methods of production (WO20009049138): the emerging recognition of the importance of virus neutralization at the epithelial/endothelial interface
Q36973592Cytomegalovirus vaccines fail to induce epithelial entry neutralizing antibodies comparable to natural infection
Q33351523Cytomegalovirus: pathogen, paradigm, and puzzle
Q37574334Developing a Vaccine against Congenital Cytomegalovirus (CMV) Infection: What Have We Learned from Animal Models? Where Should We Go Next?
Q36757818Development of a high-throughput assay to measure the neutralization capability of anti-cytomegalovirus antibodies
Q58598607Development of a primary human cell model for the study of human cytomegalovirus replication and spread within salivary epithelium
Q90271787Development of novel vaccines against human cytomegalovirus
Q92890550Differential Expression of PDGF Receptor-α in Human Placental Trophoblasts Leads to Different Entry Pathways by Human Cytomegalovirus Strains
Q38741498Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 Expression.
Q91198936Distribution of the CMV glycoprotein gH/gL/gO and gH/gL/pUL128/pUL130/pUL131A complex variants and associated clinical manifestations in infants infected congenitally or postnatally
Q37997733Diverse immune evasion strategies by human cytomegalovirus
Q57039007Dynamin is required for efficient cytomegalovirus maturation and envelopment
Q37875379Early inhibitors of human cytomegalovirus: state-of-art and therapeutic perspectives
Q37018933Efficient replication of rhesus cytomegalovirus variants in multiple rhesus and human cell types
Q95661029Enhancement of guinea pig cytomegalovirus infection by two endogenously expressed components of the pentameric glycoprotein complex in epithelial cells
Q42220221Entry of human cytomegalovirus into porcine endothelial cells depends on both the cellular vascular origin and the viral strain
Q54216733Expression levels of glycoprotein O (gO) vary between strains of human cytomegalovirus, influencing the assembly of gH/gL complexes and virion infectivity.
Q38793250Expression of Oncogenic Alleles Induces Multiple Blocks to Human Cytomegalovirus Infection
Q40178622Fibroblast-adapted human CMV vaccines elicit predominantly conventional CD8 T cell responses in humans.
Q90600086First Impressions-the Potential of Altering Initial Host-Virus Interactions for Rational Design of Herpesvirus Vaccine Vectors
Q37519151Functional screening for anti-CMV biologics identifies a broadly neutralizing epitope of an essential envelope protein
Q38796870Genetic Stability of Bacterial Artificial Chromosome-Derived Human Cytomegalovirus during Culture In Vitro.
Q38411353Genetic variability of cytomegalovirus glycoprotein O in hematopoietic stem cell transplant recipients
Q33918304Glycoprotein B switches conformation during murid herpesvirus 4 entry
Q36517126Guinea Pig Cytomegalovirus (GPCMV): A Model for the Study of the Prevention and Treatment of Maternal-Fetal Transmission
Q98461001Guinea pig cytomegalovirus trimer complex gH/gL/gO uses PDGFRA as universal receptor for cell fusion and entry
Q40877837HCMV Induces Macropinocytosis for Host Cell Entry in Fibroblasts
Q36501775HCMV gB shares structural and functional properties with gB proteins from other herpesviruses.
Q36893722HCMV gH/gL/UL128-131 interferes with virus entry into epithelial cells: evidence for cell type-specific receptors
Q37673149HCMV infection of human trophoblast progenitor cells of the placenta is neutralized by a human monoclonal antibody to glycoprotein B and not by antibodies to the pentamer complex
Q33798083HCMV spread and cell tropism are determined by distinct virus populations
Q64235200HCMV trimer- and pentamer-specific antibodies synergize for virus neutralization but do not correlate with congenital transmission
Q89554848Herpes Simplex Virus Glycoprotein C Regulates Low-pH Entry
Q34285628Herpes virus fusion and entry: a story with many characters.
Q33727577Herpesvirus Entry into Host Cells Mediated by Endosomal Low pH.
Q26774203Herpesvirus gB: A Finely Tuned Fusion Machine
Q26863328Herpesviruses and intermediate filaments: close encounters with the third type
Q37436158Heterogeneous pathways of maternal-fetal transmission of human viruses (review).
Q40653356Host protein Snapin interacts with human cytomegalovirus pUL130 and affects viral DNA replication
Q36535574Human CMV infection of endothelial cells induces an angiogenic response through viral binding to EGF receptor and beta1 and beta3 integrins
Q92127331Human Cytomegalovirus Cell Tropism and Host Cell Receptors
Q92225749Human Cytomegalovirus Enters the Primary CD34+ Hematopoietic Progenitor Cells Where It Establishes Latency by Macropinocytosis
Q39100413Human Cytomegalovirus Requires Epidermal Growth Factor Receptor Signaling To Enter and Initiate the Early Steps in the Establishment of Latency in CD34+ Human Progenitor Cells.
Q35745418Human Cytomegalovirus UL135 and UL136 Genes Are Required for Postentry Tropism in Endothelial Cells
Q35991173Human Cytomegalovirus gH/gL Forms a Stable Complex with the Fusion Protein gB in Virions
Q35913890Human Cytomegalovirus gH/gL/gO Promotes the Fusion Step of Entry into All Cell Types, whereas gH/gL/UL128-131 Broadens Virus Tropism through a Distinct Mechanism
Q38732318Human Cytomegalovirus miR-UL148D Facilitates Latent Viral Infection by Targeting Host Cell Immediate Early Response Gene 5.
Q38753357Human Cytomegalovirus nuclear egress and secondary envelopment are negatively affected in the absence of cellular p53.
Q84974854Human Cytomegalovirus: Propagation, Quantification, and Storage
Q36936292Human cytomegalovirus (HCMV) glycoprotein gB promotes virus entry in trans acting as the viral fusion protein rather than as a receptor-binding protein
Q33649006Human cytomegalovirus TR strain glycoprotein O acts as a chaperone promoting gH/gL incorporation into virions but is not present in virions
Q36325778Human cytomegalovirus and human immunodeficiency virus type-1 co-infection in human cervical tissue
Q37431029Human cytomegalovirus entry into cells
Q34230355Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner
Q36741322Human cytomegalovirus gH stability and trafficking are regulated by ER-associated degradation and transmembrane architecture
Q92709054Human cytomegalovirus glycoprotein B variants affect viral entry, cell fusion, and genome stability
Q35531288Human cytomegalovirus glycoprotein gO complexes with gH/gL, promoting interference with viral entry into human fibroblasts but not entry into epithelial cells
Q36974741Human cytomegalovirus glycoproteins gB and gH/gL mediate epithelial cell-cell fusion when expressed either in cis or in trans
Q36232248Human cytomegalovirus induction of a unique signalsome during viral entry into monocytes mediates distinct functional changes: a strategy for viral dissemination
Q37967568Human cytomegalovirus infection and atherothrombosis
Q41909075Human cytomegalovirus infection of langerhans-type dendritic cells does not require the presence of the gH/gL/UL128-131A complex and is blocked after nuclear deposition of viral genomes in immature cells
Q35780389Human cytomegalovirus is protected from inactivation by reversible binding to villous trophoblasts
Q36363329Human cytomegalovirus pUL78 G protein-coupled receptor homologue is required for timely cell entry in epithelial cells but not fibroblasts
Q36587164Human cytomegalovirus tropism for endothelial cells: not all endothelial cells are created equal
Q34422068Human cytomegalovirus tropism for mucosal myeloid dendritic cells
Q36289031Human cytomegalovirus uses two distinct pathways to enter retinal pigmented epithelial cells
Q21089588Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex
Q38430703Human cytomegalovirus: taking the strain
Q24635001Human herpesvirus 6 glycoprotein complex formation is required for folding and trafficking of the gH/gL/gQ1/gQ2 complex and its cellular receptor binding
Q37772887Human herpesvirus-6 entry into host cells
Q41773417Identification by mass spectrometry and immune response analysis of guinea pig cytomegalovirus (GPCMV) pentameric complex proteins GP129, 131 and 133.
Q34992770Identification of a neutralizing epitope within antigenic domain 5 of glycoprotein B of human cytomegalovirus
Q92252211Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infection
Q37252891Impact of sequence variation in the UL128 locus on production of human cytomegalovirus in fibroblast and epithelial cells
Q30832341Importance of Highly Conserved Peptide Sites of Human Cytomegalovirus gO for Formation of the gH/gL/gO Complex
Q36208168Inactivation of the Human Cytomegalovirus US20 Gene Hampers Productive Viral Replication in Endothelial Cells
Q36146446Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus
Q36736886Infection of a Single Cell Line with Distinct Strains of Human Cytomegalovirus Can Result in Large Variations in Virion Production and Facilitate Efficient Screening of Virus Protein Function
Q36414448Infection of vascular endothelial cells with human cytomegalovirus under fluid shear stress reveals preferential entry and spread of virus in flow conditions simulating atheroprone regions of the artery
Q38838830Inhibition of endocytic pathways impacts cytomegalovirus maturation.
Q34708600Intravaginal cytomegalovirus (CMV) challenge elicits maternal viremia and results in congenital transmission in a guinea pig model
Q38711117Loss of the Human Cytomegalovirus US16 Protein Abrogates Virus Entry into Endothelial and Epithelial Cells by Reducing the Virion Content of the Pentamer.
Q33769277Low pH-induced conformational change in herpes simplex virus glycoprotein B.
Q35382962Low-pH-dependent changes in the conformation and oligomeric state of the prefusion form of herpes simplex virus glycoprotein B are separable from fusion activity
Q27683850Mechanism for neutralizing activity by the anti-CMV gH/gL monoclonal antibody MSL-109
Q35599273Modeling of human cytomegalovirus maternal-fetal transmission in a novel decidual organ culture
Q38257810Models of vertical cytomegalovirus (CMV) transmission and pathogenesis
Q41786247Mutational mapping of UL130 of human cytomegalovirus defines peptide motifs within the C-terminal third as essential for endothelial cell infection
Q39451875Mutational mapping of pUL131A of human cytomegalovirus emphasizes its central role for endothelial cell tropism
Q54254744Navigating the Host Cell Response during Entry into Sites of Latent Cytomegalovirus Infection.
Q47167247Neutralization of Human Cytomegalovirus Entry into Fibroblasts and Epithelial Cells
Q42284197Neutralizing antibodies are unable to inhibit direct viral cell-to-cell spread of human cytomegalovirus
Q64890257Novel trimeric human cytomegalovirus glycoprotein B elicits a high-titer neutralizing antibody response.
Q63246311OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism
Q41881987Onset of human cytomegalovirus replication in fibroblasts requires the presence of an intact vimentin cytoskeleton
Q35076699Open reading frames carried on UL/b' are implicated in shedding and horizontal transmission of rhesus cytomegalovirus in rhesus monkeys.
Q34426442PDGF receptor-α does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway
Q60960757Pathogen at the Gates: Human Cytomegalovirus Entry and Cell Tropism
Q91219173Pathogen interactions with endothelial cells and the induction of innate and adaptive immunity
Q34885758Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells
Q37032510Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer
Q40330182Pneumonitis in human cytomegalovirus infection
Q36286850Polyethylene glycol-mediated fusion of herpes simplex type 1 virions with the plasma membrane of cells that support endocytic entry
Q36812617Preventing Congenital Cytomegalovirus Infection: Protection to a 'T'.
Q37409233Production of Cytomegalovirus Dense Bodies by Scalable Bioprocess Methods Maintains Immunogenicity and Improves Neutralizing Antibody Titers
Q42081310Protein pUL128 of human cytomegalovirus is necessary for monocyte infection and blocking of migration
Q39714762RASCAL is a new human cytomegalovirus-encoded protein that localizes to the nuclear lamina and in cytoplasmic vesicles at late times postinfection
Q54347426Rapid and accurate determination of the potency of varicella vaccine by quantitative polymerase chain reaction.
Q39304512Recombinant HCMV UL128 expression and functional identification of PBMC-attracting activity in vitro
Q34090187Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication.
Q59349678Restriction of human cytomegalovirus infection by galectin-9
Q57061992Role of PDGF receptor-α during human cytomegalovirus entry into fibroblasts
Q39336485Role of human cytomegalovirus genotype polymorphisms in AIDS patients with cytomegalovirus retinitis
Q33712506Role of the UL45 protein in herpes simplex virus entry via low pH-dependent endocytosis and its relationship to the conformation and function of glycoprotein B
Q35866191Scanning Mutagenesis of Human Cytomegalovirus Glycoprotein gH/gL.
Q34642568Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture
Q35090089Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes
Q34317887Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody
Q27487974Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme
Q28538007Systematic microRNA analysis identifies ATP6V0C as an essential host factor for human cytomegalovirus replication
Q37685690Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions
Q37183914Tegument proteins of human cytomegalovirus
Q40686811Tetraspanin CD151 Promotes Initial Events in Human Cytomegalovirus Infection
Q38837603Tetraspanins in infections by human cytomegalo- and papillomaviruses
Q40483485The D-form of a novel heparan binding peptide decreases cytomegalovirus infection in vivo and in vitro.
Q34819531The HCMV gH/gL/UL128-131 complex triggers the specific cellular activation required for efficient viral internalization into target monocytes
Q59354480The Human Cytomegalovirus Trimer and Pentamer Promote Sequential Steps in Entry into Epithelial and Endothelial Cells at Cell Surfaces and Endosomes
Q36878894The Human Cytomegalovirus UL116 Gene Encodes an Envelope Glycoprotein Forming a Complex with gH Independently from gL
Q37256740The M33 chemokine receptor homolog of murine cytomegalovirus exhibits a differential tissue-specific role during in vivo replication and latency.
Q37378850The Microtubule Inhibitor Podofilox Inhibits an Early Entry Step of Human Cytomegalovirus
Q92511027The N Terminus of Human Cytomegalovirus Glycoprotein O Is Important for Binding to the Cellular Receptor PDGFRα
Q36827232The ULb' region of the human cytomegalovirus genome confers an increased requirement for the viral protein kinase UL97.
Q36086685The US16 gene of human cytomegalovirus is required for efficient viral infection of endothelial and epithelial cells
Q38940024The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis
Q33609914The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus
Q40061531The infection of human primary cells and cell lines by human cytomegalovirus: new tropism and new reservoirs for HCMV.
Q40340374The m74 gene product of murine cytomegalovirus (MCMV) is a functional homolog of human CMV gO and determines the entry pathway of MCMV.
Q100762135The structural basis of herpesvirus entry
Q37296023The susceptibility of primary cultured rhesus macaque kidney epithelial cells to rhesus cytomegalovirus strains.
Q58327099The transcriptome of human mammary epithelial cells infected with the HCMV-DB strain displays oncogenic traits
Q38252422The use of microRNA by human viruses: lessons from NK cells and HCMV infection
Q34916655The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex
Q59356187There Is Always Another Way! Cytomegalovirus' Multifaceted Dissemination Schemes
Q36281094Vaccine-Derived Neutralizing Antibodies to the Human Cytomegalovirus gH/gL Pentamer Potently Block Primary Cytotrophoblast Infection
Q34742892Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaques.
Q39502095Vectored co-delivery of human cytomegalovirus gH and gL proteins elicits potent complement-independent neutralizing antibodies
Q37161687Viral binding-induced signaling drives a unique and extended intracellular trafficking pattern during infection of primary monocytes
Q26745798Virion Glycoprotein-Mediated Immune Evasion by Human Cytomegalovirus: a Sticky Virus Makes a Slick Getaway
Q37146814gH/gL supercomplexes at early stages of herpesvirus entry

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