Acidification of the endocytic and exocytic pathways

scientific article published on January 1986

Acidification of the endocytic and exocytic pathways is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1146/ANNUREV.BI.55.070186.003311
P698PubMed publication ID2874766

P2093author name stringHelenius A
Mellman I
Fuchs R
P407language of work or nameEnglishQ1860
P1104number of pages38
P304page(s)663-700
P577publication date1986-01-01
P1433published inAnnual Review of BiochemistryQ567356
P1476titleAcidification of the endocytic and exocytic pathways
P478volume55

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Q37590087Exocytosis from neuronal large dense-cored vesicles
Q36135389Expression of 16 kDa proteolipid of vacuolar-type H(+)-ATPase in human pancreatic cancer
Q34020609Expression of a proteolipid gene from a high-copy-number plasmid confers trifluoperazine resistance to Saccharomyces cerevisiae
Q41201766Expression of beta 2-microglobulin-free HLA class I alpha-chains on activated T cells requires internalization of HLA class I heterodimers
Q40589703Extracellular acidification alters lysosomal trafficking in human breast cancer cells
Q39062953Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology
Q46968580F1-like properties of an ATPase from the archaebacterium Halobacterium saccharovorum
Q67654415FITC-dextran as a probe for endosome function and localization in kidney
Q37442480Fabrication of pRNA nanoparticles to deliver therapeutic RNAs and bioactive compounds into tumor cells
Q35773185Fate of Listeria monocytogenes in murine macrophages: evidence for simultaneous killing and survival of intracellular bacteria
Q81613848Flow cytometric detection of perforin upregulation in human CD8 T cells
Q41053838Flow cytometric sorting and biochemical characterization of the late endosomal rab7-containing compartment.
Q43070506Fluorescent ligands for studying neuropeptide receptors by confocal microscopy.
Q34286193Fluorescent pigments of the retinal pigment epithelium and age-related macular degeneration
Q34609485Folate-mediated intracellular drug delivery increases the anticancer efficacy of nanoparticulate formulation of arsenic trioxide
Q40043591Formation of rhinovirus-soluble ICAM-1 complexes and conformational changes in the virion.
Q24310771Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation
Q42820649Fractionation of endocytic vesicles and glucose-transporter-containing vesicles in rat adipocytes
Q38705664From blood-brain barrier to blood-brain interface: new opportunities for CNS drug delivery
Q59067805From organelle to organelle
Q27472928Functional analysis of hepatitis C virus envelope proteins, using a cell-cell fusion assay
Q37618788Functional analysis of lysosomes during mouse preimplantation embryo development
Q57344870Functional aqueous assemblies of linear-dendron hybrids
Q38095361Functional block copolymer assemblies responsive to tumor and intracellular microenvironments for site-specific drug delivery and enhanced imaging performance.
Q34641749Functional block copolymer nanoparticles: toward the next generation of delivery vehicles
Q39094332Functional coupling of V-ATPase and CLC-5.
Q36274983Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes
Q42456411Functional expression of a vacuolar-type H+-ATPase in the plasma membrane and intracellular vacuoles of Trypanosoma cruzi
Q42952236Functional reconstitution of influenza virus envelopes
Q28631613Further studies on the reconstitution of glucosylceramidase activity by Sap C and anionic phospholipids
Q40117341Gamma-aminobutyric acid type B receptors are constitutively internalized via the clathrin-dependent pathway and targeted to lysosomes for degradation
Q28582354Gastric GATA-6 DNA-binding protein: proteolysis induced by cAMP
Q41488095Gene Transfer Using a Novel Fusion Protein, GAL4/Invasin
Q39581687Gene transfer into the nervous system
Q45749294Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway
Q35384428Genetic and cell biological aspects of the yeast vacuolar H(+)-ATPase
Q36218555Glucocorticoid-regulated localization of cell surface glycoproteins in rat hepatoma cells is mediated within the Golgi complex
Q68274335Glucose transporters in chromaffin cells: subcellular distribution and characterization
Q39178047Glycoprotein H and α4β1 integrins determine the entry pathway of alphaherpesviruses
Q30436006Glycoprotein-dependent acidification of vesicular stomatitis virus enhances release of matrix protein
Q45176585Glycosaminoglycans modulate activation, activity, and stability of tripeptidyl-peptidase I in vitro and in vivo
Q27935848Golgi localization and functionally important domains in the NH2 and COOH terminus of the yeast CLC putative chloride channel Gef1p
Q96822686HA stabilization promotes replication and transmission of swine H1N1 gamma influenza viruses in ferrets
Q73666817HIV-1 protein gp120 crosses the blood-brain barrier: role of adsorptive endocytosis
Q86652042Head and stalk structures of soybean vacuolar membranes
Q83228107Hemozoin produced by mammals confers heme tolerance
Q42857892Heparan sulphate-degrading endoglycosidase in liver plasma membranes
Q34127097Heterogeneity in ATP-dependent acidification in endocytic vesicles from kidney proximal tubule. Measurement of pH in individual endocytic vesicles in a cell-free system
Q58243580Heteroloaous expression of yeast prepro‐a‐factor in rat GH3cells
Q41492766Heterologous expression of delta F508 CFTR results in decreased sialylation of membrane glycoconjugates
Q47293335High-performance CE: an effective method to study lactonization of alpha2,8-linked oligosialic acid
Q41967930High-yield isolation of functionally competent endosomes from mouse lymphocytes
Q38759514History of Polymeric Gene Delivery Systems
Q36052536Hochu-ekki-to inhibits rhinovirus infection in human tracheal epithelial cells
Q37033185Host cell factors and functions involved in vesicular stomatitis virus entry
Q41871487How Glycosaminoglycans Promote Fibrillation of Salmon Calcitonin
Q41030314Hsp47 binds to the KDEL receptor and cell surface expression is modulated by cytoplasmic and endosomal pH.
Q41091293Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism
Q43153233Human rhinovirus type 2 uncoating at the plasma membrane is not affected by a pH gradient but is affected by the membrane potential
Q41111810Human- and mouse-inducible nitric oxide synthase promoters require activation of phosphatidylcholine-specific phospholipase C and NF-kappa B.
Q41919323Hyaluronan enters keratinocytes by a novel endocytic route for catabolism
Q37854742Hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis and its safety in pregnancy
Q45078956Hypertonic sucrose inhibition of endocytic transport suggests multiple early endocytic compartments
Q51205868Hypothesis: The Ecological Advantage of Chloroplast ER - The Ability to Outcompete at Low Dissolved CO(2) Concentrations.
Q40686820ICAM-1 Binding Rhinoviruses A89 and B14 Uncoat in Different Endosomal Compartments
Q38183567IFITM proteins-cellular inhibitors of viral entry.
Q39965091IFN-gamma upregulation and protection by macrophage-adapted infectious bursal disease virus
Q28248818Identification and characterization of cathepsin B as the cellular MARCKS cleaving enzyme
Q24312304Identification and characterization of the gene encoding a second proteolipid subunit of human vacuolar H(+)-ATPase (ATP6F)
Q24646771Identification and functional characterization of a voltage-gated chloride channel and its novel splice variant in taste bud cells
Q22010798Identification of an acid-activated Cl(-) channel from human skeletal muscles
Q77121488Identification of cystic fibrosis transmembrane conductance regulator in renal endosomes
Q42678438Identification of major proteins associated with Dictyostelium discoideum endocytic vesicles
Q39251064Imaging of lysosomal pH changes with a fluorescent sensor containing a novel lysosome-locating group
Q56395701Immune Evasion of Enteroviruses Under Innate Immune Monitoring
Q46136552Immunocytochemical Localization of the Vacuolar H-ATPase in Maize Root Tip Cells
Q69727293Immunoisolation using magnetic solid supports: subcellular fractionation for cell-free functional studies
Q44759442Immunological detection of the mitochondrial F1-ATPase alpha subunit in the matrix of rat liver peroxisomes. A protein involved in organelle biogenesis?
Q36220850Impaired lysosomes in a temperature-sensitive mutant of Chinese hamster ovary cells
Q33659110In vitro bioassay of endotoxin using fluorescein as a pH indicator in a macrophage cell culture system
Q36954167In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101
Q58763062In vitro cellular localization and efficient accumulation of fluorescently tagged biomaterials from monodispersed chitosan nanoparticles for elucidation of controlled release pathways for drug delivery systems
Q43181151In vitro evaluation of folic acid modified carboxymethyl chitosan nanoparticles loaded with doxorubicin for targeted delivery
Q41930505In vitro fusion of endocytic vesicles: effects of reagents that alter endosomal pH.
Q40996848In vitro fusion of phagosomes with different endocytic organelles from J774 macrophages.
Q36167940In vitro methods in the study of viral and prion permeability across the blood-brain barrier
Q36224257In vitro reconstitution of intercompartmental protein transport to the yeast vacuole
Q37272347In vitro studies of endocytic membrane traffic
Q74340494In vivo interaction between alveolar macrophages and Cryptococcus neoformans
Q73486513In vivo rapid reduction of alloantigen-activated CD8+ mature cytotoxic T cells by inhibitors of acidification of intracellular organelles, prodigiosin 25-C and concanamycin B
Q73707598Inactivation and proteolytic degradation of perforin within lytic granules upon neutralization of acidic pH
Q35995074Incorporation and controlled release of silyl ether prodrugs from PRINT nanoparticles
Q36155333Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core
Q53520906Increased pH and tumorigenicity of fibroblasts expressing a yeast proton pump.
Q40412413Increased rhinovirus replication in nasal mucosa cells in allergic subjects is associated with increased ICAM-1 levels and endosomal acidification and is inhibited by L-carbocisteine
Q44615924Induction of neurite outgrowth of PC12 cells by an inhibitor of vacuolar H(+)-ATPase, bafilomycin A1.
Q41494084Induction of phagocytic activity of M1 cells by an inhibitor of vacuolar H+-ATPase, bafilomycin A1.
Q45421104Infectious bursal disease virus infection induces macrophage activation via p38 MAPK and NF-kappaB pathways
Q33851643Infectious entry by amphotropic as well as ecotropic murine leukemia viruses occurs through an endocytic pathway
Q39889673Influence of subculturing on gene expression in a Theileria lestoquardi-infected cell line
Q54230830Influenza Hemagglutinin Protein Stability, Activation, and Pandemic Risk.
Q32162762Inhibition effects of di(2-ethylhexyl)phthalate on mouse-liver lysosomal vacuolar H(+)-ATPase
Q41152773Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudine
Q28323345Inhibition of Human Immunodeficiency Virus Infectivity by Chloroquine
Q40920297Inhibition of Na+-H+ exchange impairs receptor-mediated albumin endocytosis in renal proximal tubule-derived epithelial cells from opossum
Q28360301Inhibition of Na+-H+ exchanger-3 interferes with apical receptor-mediated endocytosis via vesicle fusion
Q38730715Inhibition of breast cancer metastasis by paclitaxel-loaded pH responsive poly(β-amino ester) copolymer micelles
Q41517909Inhibition of cell growth by bafilomycin A1, a selective inhibitor of vacuolar H(+)-ATPase
Q34354703Inhibition of endosomal/lysosomal degradation increases the infectivity of human immunodeficiency virus
Q40046355Inhibition of endosome-lysosome system acidification enhances porcine circovirus 2 infection of porcine epithelial cells
Q44627991Inhibition of influenza A virus sialidase activity by sulfatide
Q42269980Inhibition of mitogen-induced DNA synthesis by bafilomycin A1 in Swiss 3T3 fibroblasts.
Q57269820Inhibition of the vacuolar H+-ATPase perturbs the transport, sorting, processing and release of regulated secretory proteins
Q39434688Inhibitors of intravesicular acidification protect against Shiga toxin in a pH-independent manner
Q89864744Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells
Q33794681Initial events in infectious salmon anemia virus infection: evidence for the requirement of a low-pH step.
Q40463902Insertion of targeting domains into the envelope glycoprotein of Moloney murine leukemia virus (MoMLV)-based vectors modulates the route of mCAT-1-mediated viral entry.
Q35189406Insider information: what viruses tell us about endocytosis
Q28616315Insulin receptor internalization and signalling
Q36719682Insulin receptor kinase activation releases a constraint maintaining the receptor on microvilli
Q46716340Interaction of 125I-labelled ceruloplasmin with human trophoblast cells in vitro
Q41911744Interactions of cholera toxin with isolated hepatocytes. Effects of low pH, chloroquine and monensin on toxin internalization, processing and action
Q36739568Intercellular transport of lysosomal acid lipase mediates lipoprotein cholesteryl ester metabolism in a human vascular endothelial cell-fibroblast coculture system
Q42770973Interference with the endosomal acidification by a monoclonal antibody directed toward the 116 (100)-kD subunit of the vacuolar type proton pump
Q42822091Intracellular Ca2+ storage in acidocalcisomes of Trypanosoma cruzi
Q41508323Intracellular chromobody delivery by mesoporous silica nanoparticles for antigen targeting and visualization in real time
Q33715962Intracellular fate of spherical nucleic acid nanoparticle conjugates.
Q36218414Intracellular fusion of sequentially formed endocytic compartments
Q36849355Intracellular precursors and secretion of alkaline extracellular protease of Yarrowia lipolytica
Q40185789Intracellular route and mechanism of action of ERB-hRNase, a human anti-ErbB2 anticancer immunoagent
Q38723115Intracellular trafficking and cellular uptake mechanism of PHBV nanoparticles for targeted delivery in epithelial cell lines.
Q41006762Intracellular trafficking of tropoelastin
Q45941447Intracellular transport of class II MHC molecules directed by invariant chain.
Q34719366Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins
Q38684644Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development.
Q37113422Intravesicular acidification correlates with binding of ADP-ribosylation factor to microsomal membranes
Q92717896Inventory of molecular markers affecting biological characteristics of avian influenza A viruses
Q28201098Involvement of cathepsin H in the processing of the hydrophobic surfactant-associated protein C in type II pneumocytes
Q30734938Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II pneumocytes of the human lung.
Q38230708Ion transport in pigmentation
Q40367090Ionic milieu controls the compartment-specific activation of pro-opiomelanocortin processing in AtT-20 cells
Q30442290Isolation and characterization of the Fc receptor from the fetal yolk sac of the rat
Q33569930Isolation and sequence of a cDNA clone encoding the 31-kDa subunit of bovine kidney vacuolar H+-ATPase
Q41678802Isolation by fluorescence-activated cell sorting of Chinese hamster ovary cell lines with pleiotropic, temperature-conditional defects in receptor recycling
Q36483877Jaagsiekte sheep retrovirus utilizes a pH-dependent endocytosis pathway for entry.
Q42984444Japanese encephalitis virus infection in Vero cells: the involvement of intracellular acidic vesicles in the early phase of viral infection was observed with the treatment of a specific vacuolar type H+-ATPase inhibitor, bafilomycin A1.
Q40915648Kinetics of doxorubicin handling in the LLC-PK1 kidney epithelial cell line is mediated by both vesicle formation and P-glycoprotein drug transport.
Q72098072Kinetics of endosomal pH evolution in Dictyostelium discoideum amoebae Study by fluorescence spectroscopy
Q27470014Kinetics of endosome acidification detected by mutant and wild-type Semliki Forest virus
Q36217308Kinetics of endosome acidification in mutant and wild-type Chinese hamster ovary cells
Q36217696Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins
Q71567625Kinetics of receptor-mediated endocytosis of albumin in cells derived from the proximal tubule of the kidney (opossum kidney cells): influence of Ca2+ and cAMP
Q41734072L is for lytic granules: lysosomes that kill
Q45388029Leupeptin and ammonium chloride inhibit intrinsic factor mediated transcytosis of [57Co]cobalamin across polarized renal epithelial cells
Q36171734Levofloxacin inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells.
Q35617859Ligand-mediated autophosphorylation activity of the epidermal growth factor receptor during internalization
Q30486673Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes
Q34119970Linkage of azurophil granule secretion in neutrophils to chloride ion transport and endosomal transcytosis
Q33646634Liposomes as a gene delivery system
Q47073906Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo
Q42137340Local pH-dependent conformational changes leading to proteolytic susceptibility of cystatin C.
Q35595148Localization of a proton-pumping ATPase in rat kidney
Q71940863Localization of cyclic-AMP receptors with acidosomes in Dictyostelium discoideum
Q28592336Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules
Q41571336Low cytoplasmic pH inhibits endocytosis and transport from the trans-Golgi network to the cell surface
Q42092014Low endocytic pH and capsid protein autocleavage are critical components of Flock House virus cell entry
Q51770076Lucifer Yellow as a live cell fluorescent probe for imaging water transport in subcellular organelles.
Q38611314Lumenal and transmembrane domains play a role in sorting type I membrane proteins on endocytic pathways
Q67849812Lumenal labeling of rat hepatocyte endocytic compartments. Distribution of several acid hydrolases and membrane receptors
Q38684097Lysosomal enzyme replacement therapies: Historical development, clinical outcomes, and future perspectives
Q72591829Lysosomal hydrolases are present in melanosomes and are elevated in melanizing cells
Q42371528Lysosomal pH-inducible supramolecular dissociation of polyrotaxanes possessing acid-labile N-triphenylmethyl end groups and their therapeutic potential for Niemann-Pick type C disease
Q33179423Lysosomal trapping as an important mechanism involved in the cellular distribution of perazine and in pharmacokinetic interaction with antidepressants
Q38256378Lysosomal-specific cholesterol reduction by biocleavable polyrotaxanes for ameliorating Niemann-Pick type C disease.
Q37228891Lysosomes in apoptosis
Q36885390Lysosomes: fusion and function
Q34023676Lytic cycle of Toxoplasma gondii
Q33957690MHC class II-restricted antigen processing and presentation
Q45116951Macrophage activation by a DNA/cationic liposome complex requires endosomal acidification and TLR9-dependent and -independent pathways.
Q34060313Macropinosome maturation and fusion with tubular lysosomes in macrophages.
Q44895882Maturation of human tripeptidyl-peptidase I in vitro
Q77575409Maturation of phagosomes is accompanied by specific patterns of small GTPases
Q40820717Measurement of secretory vesicle pH reveals intravesicular alkalinization by vesicular monoamine transporter type 2 resulting in inhibition of prohormone cleavage
Q106995827Mechanism of action of hydroxychloroquine as an antirheumatic drug
Q34479011Mechanisms and clinical implications of renal drug excretion
Q33185845Mechanisms of cellular distribution of psychotropic drugs. Significance for drug action and interactions
Q33868181Mechanisms of internalization of Staphylococcus aureus by cultured human osteoblasts
Q30278773Membrane associated cancer-oocyte neoantigen SAS1B/ovastacin is a candidate immunotherapeutic target for uterine tumors
Q38780411Membrane dynamics in mammalian embryogenesis: Implication in signal regulation
Q40735884Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity
Q40293294Membrane perforations inhibit lysosome fusion by altering pH and calcium in Listeria monocytogenes vacuoles
Q75294636Membrane trafficking along the phagocytic pathway
Q41732273Membrane transport in rat liver endocytic pathways: preparation, biochemical properties and functional roles of hepatic endosomes
Q72150602Metabolic pathways in Ehrlich ascites tumor cells recovering from a low bioenergetic status
Q42737491Metal ions and electrolytes regulate the dissociation of heme from human hemopexin at physiological pH.
Q89561704Misfolded amyloid-β-42 impairs the endosomal-lysosomal pathway
Q37691503Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model.
Q46115420Modifying mesoporous silica nanoparticles to avoid the metabolic deactivation of 6-mercaptopurine and methotrexate in combinatorial chemotherapy
Q77675957Modulation of phagosome processing as a key strategy for Mycobacterium avium survival within macrophages
Q37533644Molecular and cellular mechanisms involved in transepithelial transport
Q36389592Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
Q35240301Molecular biology of G-protein-coupled receptors
Q24291060Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network
Q40856173Molecular cloning and characterization of an intracellular chloride channel in the proximal tubule cell line, LLC-PK1.
Q42618186Molecular cloning and characterization of the structural gene coding for the developmentally regulated lysosomal enzyme, alpha-mannosidase, in Dictyostelium discoideum
Q35622988Molecular mechanisms of host-pathogen interaction: entry and survival of mycobacteria in macrophages.
Q39689071Molecular pathogenesis of neurotropic viral infections
Q38096444Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products.
Q41522162Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
Q71847822Monensin and verapamil do not alter intracellular localisation of daunorubicin in multidrug resistant human KB cells
Q42127390Monensin disruption of neutrophil granule genesis
Q88935183Morphology and ultrastructure of the gut in Spadella cephaloptera (chaetognatha)
Q33922460Mouse B lymphocyte specific endocytosis and recycling of MHC class II molecules
Q40484328Multidrug resistance and mutagenesis
Q26739932Multiple Roles of the Small GTPase Rab7
Q63255707Multivesicular bodies mature from the trans-Golgi network/early endosome in Arabidopsis
Q33808160Mutations in the E1 hydrophobic domain of rubella virus impair virus infectivity but not virus assembly
Q42056773Mutations in vacuolar H+ -ATPase subunits lead to biliary developmental defects in zebrafish.
Q28575217NHE3 Na+/H+ exchanger supports proximal tubular protein reabsorption in vivo
Q34143409NHE3 serves as a molecular tool for cAMP-mediated regulation of receptor-mediated endocytosis
Q38306096NMR evidence for oligosaccharide release from the dendritic-cell specific intercellular adhesion molecule 3-grabbing non-integrin-related (CLEC4M) carbohydrate recognition domain at low pH.
Q49166359Nanobody-triggered lockdown of VSRs reveals ligand reloading in the Golgi.
Q36853778Nanocarriers enhance Doxorubicin uptake in drug-resistant ovarian cancer cells.
Q24290827Negative factor from SIV binds to the catalytic subunit of the V-ATPase to internalize CD4 and to increase viral infectivity
Q39188137Nicotinamide inhibits the lysosomal cathepsin b-like protease and kills African trypanosomes
Q64274109Non-Viral Delivery System and Targeted Bone Disease Therapy
Q28142071Normal lysosomal morphology and function in LAMP-1-deficient mice
Q33676634Novel pH-sensitive polyacetal-based block copolymers for controlled drug delivery.
Q43938273Off-on-off fluorescent chemosensor for pH measurement with a terbium(iii) complex based on a tripodal salicylic-acid derivative
Q41695135Oligomerization and intracellular protein transport: dimerization of intestinal dipeptidylpeptidase IV occurs in the Golgi apparatus
Q45088423Omeprazole induces apoptosis in jurkat cells
Q42514828Omeprazole inhibits natural killer cell functions
Q46534431On the mechanism of hyperacidification in lemon. Comparison of the vacuolar H(+)-ATPase activities of fruits and epicotyls
Q41094039On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells.
Q35057000Organelle acidification and disease
Q27930188Organelle acidification is important for localisation of vacuolar proteins in Saccharomyces cerevisiae
Q41724391Organelle pH studies using targeted avidin and fluorescein-biotin
Q34588909Osteoclastic acidification pathways during bone resorption
Q34054137PEGylated polyamidoamine dendrimers with bis-aryl hydrazone linkages for enhanced gene delivery.
Q34208247Pathways of processing of the gastrin precursor in rat antral mucosa
Q57594290Penetratin tandemly linked to a CTL peptide induces anti-tumour T-cell responses via a cross-presentation pathway
Q40149570Penetration and replication of Edwardsiella spp. in HEp-2 cells
Q33815435Peptide exchange in MHC molecules
Q28538039Peptide-mediated liposomal Doxorubicin enhances drug delivery efficiency and therapeutic efficacy in animal models
Q41064448Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.
Q73111134Perturbation of epidermal growth factor clearance after radioiodination and its implications
Q50512962Phagocytosis of yeast: a method for concurrent quantification of binding and internalization using differential interference contrast microscopy.
Q46902375Phagolysosomal pH in alveolar macrophages from smokers and non-smokers
Q42949358Phase separation in lipid bilayers triggered by low pH
Q42833733Phosphatidylinositol 3-kinase and Ca2+ influx dependence for ligand-stimulated internalization of the c-Kit receptor.
Q28637388Phosphorylation and internalization of gp130 occur after IL-6 activation of Jak2 kinase in hepatocytes
Q47977437Physiological consequence of disruption of the VMA1 gene in the riboflavin overproducer Ashbya gossypii
Q40515582Physiological functions of endosomal proteolysis
Q41619024Picornaviruses
Q30581160Pinpointing retrovirus entry sites in cells expressing alternatively spliced receptor isoforms by single virus imaging
Q45064469Platinum (IV) pro-drug conjugated NaYF4 :Yb(3+) /Er(3+) nanoparticles for targeted drug delivery and up-conversion cell imaging.
Q40605445Poly(2-alkylacrylic acid) polymers deliver molecules to the cytosol by pH-sensitive disruption of endosomal vesicles.
Q41914534Polymeric chloroquine as an inhibitor of cancer cell migration and experimental lung metastasis
Q38578305Polymersomes and their applications in cancer delivery and therapy
Q41540271Pool of ligand‐bound platelet‐derived growth factor β‐receptors remain activated and tyrosine phosphorylated after internalization
Q35196312Population distribution analyses reveal a hierarchy of molecular players underlying parallel endocytic pathways
Q41926356Porcine submaxillary mucin forms disulfide-linked multimers through its amino-terminal D-domains
Q69536940Postembedding detection of acidic compartments
Q73731997Potential role of vacuolar H-adenosine triphosphatase in neointimal formation in cultured human saphenous vein
Q41566479Prelysosomal acidic vacuoles in Dictyostelium discoideum
Q39476079Preparation of non-aggregated fluorescent nanodiamonds (FNDs) by non-covalent coating with a block copolymer and proteins for enhancement of intracellular uptake
Q51613172Processing of the gastrin precursor. Modulation of phosphorylated, sulfated, and amidated products
Q41370851Prodigiosin 25-C uncouples vacuolar type H(+)-ATPase, inhibits vacuolar acidification and affects glycoprotein processing
Q42159115Prodigiosins uncouple lysosomal vacuolar-type ATPase through promotion of H+/Cl- symport
Q42090065Productive entry pathways of human rhinoviruses
Q36386960Profiling lipid-protein interactions using nonquenched fluorescent liposomal nanovesicles and proteome microarrays
Q43547877Progression of microalbuminuria in SHR is associated with lower expression of critical components of the apical endocytic machinery in the renal proximal tubule.
Q54307087Properties of ATPase activity associated with peroxisomes of rat and bovine liver
Q84747750Prosaposin sorting is mediated by oligomerization
Q46503400Protein kinase A regulates chloride conductance in endocytic vesicles from proximal tubule
Q37694922Protein kinase C regulates MARCKS cycling between the plasma membrane and lysosomes in fibroblasts.
Q42598142Protein uptake by bacteria: An endocytosis-like process in the planctomycete Gemmata obscuriglobus
Q28612038Proteolysis and antigen presentation by MHC class II molecules
Q36531504Proteolysis of the major yolk glycoproteins is regulated by acidification of the yolk platelets in sea urchin embryos
Q38684254Proton Transport and pH Control in Fungi
Q86669889Proton and anion transport at the tonoplast in crassulacean-acid-metabolism plants: specificity of the malate-influx system in Kalanchoë daigremontiana
Q71771018Proton gradient formation in early endosomes from proximal tubules
Q39225828Proton translocating ATPases: issues in structure and function
Q42793819Pseudoarginine: synthesis and properties of derivatives of delta-(1-imidazolyl)norvaline
Q34190689Pumping iron: the strange partnership of the hemochromatosis protein, a class I MHC homolog, with the transferrin receptor
Q33686106Purification and reconstitution of the proton-translocating ATPase of Golgi-enriched membranes
Q35100507Purification of the Clostridium spiroforme binary toxin and activity of the toxin on HEp-2 cells
Q40539858Quantification of EGFP expression on Molt-4 T cells using calibration standards
Q38755764Quantitative Analysis of Endocytic Recycling of Membrane Proteins by Monoclonal Antibody-Based Recycling Assays
Q34418433Quantitative measurement of intraorganelle pH in the endosomal-lysosomal pathway in neurons by using ratiometric imaging with pyranine
Q29620369Rab7: a key to lysosome biogenesis
Q37348438Rabies virus stimulates nitric oxide production and CXC chemokine ligand 10 expression in macrophages through activation of extracellular signal-regulated kinases 1 and 2.
Q36215953Rapid analytical and preparative isolation of functional endosomes by free flow electrophoresis
Q35294889Rat liver endocytic coated vesicles do not exhibit ATP-dependent acidification in vitro
Q41865540Reagents for astatination of biomolecules. 5. Evaluation of hydrazone linkers in (211)At- and (125)I-labeled closo-decaborate(2-) conjugates of Fab' as a means of decreasing kidney retention
Q51063354Real-time monitoring of vesicle pH in an endocytic pathway using an EGF-conjugated two-photon probe.
Q37974590Recent advances in stealth coating of nanoparticle drug delivery systems
Q42055944Receptor-activity-modifying proteins are required for forward trafficking of the calcium-sensing receptor to the plasma membrane.
Q74526240Receptor-mediated endocytosis in kidney proximal tubules: recent advances and hypothesis
Q41927972Receptor-mediated endocytosis of angiotensin II in rat myometrial cells
Q42150866Reciprocal effects of rab7 deletion in activated and neglected T cells
Q58122191Reconstituted HDL: Drug Delivery Platform for Overcoming Biological Barriers to Cancer Therapy
Q42797079Reconstitution in vitro of the pH-dependent aggregation of pancreatic zymogens en route to the secretory granule: implication of GP-2.
Q68243038Reconstitution of the association of endocytic vacuoles and acidosomes from Dictyostelium
Q33880907Reconstitution of vesicle fusions occurring in endocytosis with a cell-free system
Q31631129Regulation of AQP6 mRNA and protein expression in rats in response to altered acid-base or water balance
Q36351024Regulation of antigen presentation by acidic pH.
Q37302318Regulation of calcium-sensing-receptor trafficking and cell-surface expression by GPCRs and RAMPs
Q33831627Regulation of endocytic pH by the Na+,K+-ATPase in living cells
Q41817734Regulation of hepatocyte plasma membrane alpha 1-adrenergic receptors by 4 beta-phorbol 12-myristate 13-acetate
Q39485522Regulation of intracellular pH in eukaryotic cells
Q42239490Regulation of membrane-type 1 matrix metalloproteinase activity by vacuolar H+-ATPases
Q44054963Regulation of secretory granule pH in insulin-secreting cells
Q44666427Regulation of tyrosinase processing and trafficking by organellar pH and by proteasome activity
Q35224251Relating surface-enhanced Raman scattering signals of cells to gold nanoparticle aggregation as determined by LA-ICP-MS micromapping.
Q41942715Relationship between pinocytic rate and uptake of transferrin by suspended rat hepatocytes
Q36553395Reminiscence of our research on membrane phospholipids in mammalian cells by using the novel technology
Q34350645Renal vacuolar H+-ATPase
Q39869648Requirement for vacuolar proton-ATPase activity during entry of influenza virus into cells
Q33619179Requirements for invasion of epithelial cells by Actinobacillus actinomycetemcomitans
Q36531385Retention of secretory proteins in an intermediate compartment and disappearance of the Golgi complex in an END4 mutant of Chinese hamster ovary cells
Q40791910Retrieval of TGN proteins from the cell surface requires endosomal acidification.
Q36937813Retrograde transport from the pre-Golgi intermediate compartment and the Golgi complex is affected by the vacuolar H+-ATPase inhibitor bafilomycin A1.
Q91860311Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA expression data (FANTOM5)
Q33781665Reversible association between the V1 and V0 domains of yeast vacuolar H+-ATPase is an unconventional glucose-induced effect
Q37246334Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles
Q73186597Rhodamine 123 accumulates extensively in the isolated perfused rat kidney and is secreted by the organic cation system
Q33578498Role for intracellular proteases in the processing and transport of class II HLA antigens
Q40883470Role of ATP7B in biliary copper excretion in a human hepatoma cell line and normal rat hepatocytes
Q36398647Role of Enzyme Receptors and Inhibitors in Regulating Proteolytic Activities of Macrophages
Q38736122Role of LAMP1 Binding and pH Sensing by the Spike Complex of Lassa Virus
Q36126724Role of TRP channels in the regulation of the endosomal pathway
Q35814223Role of receptor cycling in the regulation of angiotensin II surface receptor number and angiotensin II uptake in rat vascular smooth muscle cells
Q57374339Role of receptor-mediated endocytosis, endosomal acidification and cathepsin D in cholera toxin cytotoxicity
Q26828035Role of the bicarbonate-responsive soluble adenylyl cyclase in pH sensing and metabolic regulation
Q56396086Role of the vacuolar ATPase in the replication cycle
Q27933484Role of vacuolar acidification in protein sorting and zymogen activation: a genetic analysis of the yeast vacuolar proton-translocating ATPase
Q72134510Role of vacuolar adenosine triphosphatase in the regulation of cytosolic pH in hepatocytes
Q36531965Second messengers regulate endosomal acidification in Swiss 3T3 fibroblasts
Q36222374Selective degradation of insulin within rat liver endosomes
Q28612958Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH
Q39592862Semliki forest virus budding: assay, mechanisms, and cholesterol requirement
Q37101293Sensitivity to vanadate and isoforms of subunits A and B distinguish the osteoclast proton pump from other vacuolar H+ ATPases
Q77073723Separation of endosomes by aqueous two-phase partition and free-flow electrophoresis
Q68293149Sequential processing of epidermal growth factor in early and late endosomes of rat liver
Q40819887Sequential processing of lysosomal acid phosphatase by a cytoplasmic thiol proteinase and a lysosomal aspartyl proteinase
Q37609647Serum IgE clearance is facilitated by human FcεRI internalization
Q35089382Sex-specific effects of cigarette mentholation on brain nicotine accumulation and smoking behavior
Q30351350Sialidase activity of influenza A virus in an endocytic pathway enhances viral replication.
Q90248037Significance of Ligand-Anchored Polymers for Drug Targeting in the Treatment of Colonic Disorders
Q34660074Small-molecule regulators of autophagy and their potential therapeutic applications
Q57345679Smart Stimuli-Responsive Nano-sized Hosts for Drug Delivery
Q39643292Some general characteristics of the transport of nutrients and toxic compounds in yeasts and fungi
Q40744676Sorting and processing of secretory proteins
Q30457026Sorting and secretory pathways in exocrine cells
Q36232964Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process
Q35648960Spatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation
Q40405417Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells
Q40744778Specific modulation of Kex2/furin family proteases by potassium
Q40101850Spike protein oligomerization control of Semliki Forest virus fusion
Q37635793Sterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP).
Q38103174Stimuli responsive synthetic polypeptides derived from N-carboxyanhydride (NCA) polymerisation
Q45243331Storage and degradation of secretory proteins in adenomatous and secondary hyperplastic parathyroid cells. An immunoelectron microscope study
Q27658132Structural Characterization of the E2 Domain of APL-1, a Caenorhabditis elegans Homolog of Human Amyloid Precursor Protein, and Its Heparin Binding Site
Q34218474Structural and functional characterization of two human V-ATPase subunit gene promoters
Q37728008Structural changes of tumor necrosis factor alpha associated with membrane insertion and channel formation
Q35384447Structural conservation and functional diversity of V-ATPases
Q48305633Structural gene organization and evolutionary aspects of the V-ATPase accessory subunit Ac45.
Q37861434Structural properties of vacuolar proton pumps
Q38260407Structure and function of the yeast vacuolar membrane proton ATPase
Q37083782Structure and pharmacology of the proton-ATPases
Q36216857Structure of the novel membrane-coating material in proton-secreting epithelial cells and identification as an H+ATPase
Q83266226Structure, Function, and Evolution of Proton-ATPases
Q38260405Structure, molecular genetics, and evolution of vacuolar H+-ATPases
Q35314263Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria
Q37385618Subcellular distribution and targeting of the intracellular chloride channel p64
Q74424205Subchronic cadmium treatment affects the abundance and arrangement of cytoskeletal proteins in rat renal proximal tubule cells
Q24298213Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery
Q24531411Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptins
Q86711270Sugar nucleotides dissipate ATP-generated transmembrane pH gradient in Golgi vesicles from suspension-cell protoplasts ofChenopodium rubrum L
Q36827437Surface annexin II on placental membranes of the fetomaternal interface
Q35672613Surface modification of cobalt oxide nanoparticles using phosphonomethyl iminodiacetic acid followed by folic acid: a biocompatible vehicle for targeted anticancer drug delivery
Q42576990Surface-Cross-Linked Micelles as Multifunctionalized Organic Nanoparticles for Controlled Release, Light Harvesting, and Catalysis
Q37455123Symmetric dimethyl arginine and N-acetyl-β-D-glucosaminidase lysozimuria of proximal renal tubules as a target for nephrotoxicity in patients with rheumatoid arthritis treated with disease modifying antirheumatic drugs
Q28145518Syntaxin 7 mediates endocytic trafficking to late endosomes
Q41912199Synthesis and Evaluation of Chloroquine-Containing DMAEMA Copolymers as Efficient Anti-miRNA Delivery Vectors with Improved Endosomal Escape and Antimigratory Activity in Cancer Cells
Q41940280Synthesis and brush border expression of intrinsic factor-cobalamin receptor from rat renal cortex
Q72112886Synthesis and characterization of N-acylated, pH-sensitive ‘caged’ aminophospholipids
Q57346582Synthesis and self-assembly of pH-responsive amphiphilic poly(ε-caprolactone)-block-poly(acrylic acid) copolymer
Q37427328Synthesis, characterization, and in vitro transfection activity of charge-reversal amphiphiles for DNA delivery.
Q33445361Systematic review of hydroxychloroquine use in pregnant patients with autoimmune diseases
Q101241865TMEM16A/ANO1 calcium-activated chloride channel as a novel target for the treatment of human respiratory syncytial virus infection
Q89655663TORC1 regulates vacuole membrane composition through ubiquitin- and ESCRT-dependent microautophagy
Q39665507TRPV2 has a pivotal role in macrophage particle binding and phagocytosis
Q37093489Tactics of Mycobacterium avium subsp. paratuberculosis for intracellular survival in mononuclear phagocytes
Q35126990Tamoxifen inhibits acidification in cells independent of the estrogen receptor
Q38358020Target cell-specific DNA transfer mediated by a chimeric multidomain protein. Novel non-viral gene delivery system
Q37276857Targeted gene delivery to CD117-expressing cells in vivo with lentiviral vectors co-displaying stem cell factor and a fusogenic molecule
Q33831383Targeting of membrane transporters in renal epithelia: when cell biology meets physiology
Q36783676Temperature-sensitive transport of glycoproteins to the surface of a variant mouse lymphoma cell line
Q53846775Thallium induces apoptosis in Jurkat cells.
Q41663618The Architecture of the Rag GTPase Signaling Network.
Q35192382The Cell and Molecular Biology of Eggshell Formation in Schistosoma mansoni
Q33593973The ClC-3 Cl-/H+ antiporter becomes uncoupled at low extracellular pH
Q28475418The G215R Mutation in the Cl−/H+-Antiporter ClC-7 Found in ADO II Osteopetrosis Does Not Abolish Function but Causes a Severe Trafficking Defect
Q36944562The Histoplasma capsulatum vacuolar ATPase is required for iron homeostasis, intracellular replication in macrophages and virulence in a murine model of histoplasmosis
Q36324437The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells
Q40436256The N370S (Asn370-->Ser) mutation affects the capacity of glucosylceramidase to interact with anionic phospholipid-containing membranes and saposin C
Q74781826The Tonoplast H+-ATPase of Acer pseudoplatanus Is a Vacuolar-Type ATPase That Operates with a Phosphoenzyme Intermediate
Q42829759The acidic environment in endocytic compartments
Q73695358The antineoplastic drug lonidamine interferes with the acidification mechanism of cell organelles
Q42830196The cell adhesion molecule DdCAD-1 in Dictyostelium is targeted to the cell surface by a nonclassical transport pathway involving contractile vacuoles
Q36707417The cell biology of antigen processing
Q35069256The condensing vacuole of exocrine cells is more acidic than the mature secretory vesicle
Q40468559The conserved glycine residues in the transmembrane domain of the Semliki Forest virus fusion protein are not required for assembly and fusion.
Q82305697The delivery of an antigen from the endocytic compartment into the cytosol for cross-presentation is restricted to early immature dendritic cells
Q35131420The diffuse endocrine system: from embryogenesis to carcinogenesis.
Q37004117The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines.
Q47678072The endogenous lectins of the chick blastoderm are present in association with an apolipoprotein in distinct organelles and in the extracellular matrix
Q43959077The fate of newly synthesized V-ATPase accessory subunit Ac45 in the secretory pathway
Q24634743The fungal vacuole: composition, function, and biogenesis
Q41512888The giant organelles in beige and Chediak-Higashi fibroblasts are derived from late endosomes and mature lysosomes
Q34081123The golden age: gold nanoparticles for biomedicine
Q27486630The heterodimeric association between the membrane proteins of Semliki Forest virus changes its sensitivity to low pH during virus maturation
Q41642217The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan
Q35676581The immunological aspects of latency in tuberculosis
Q90124861The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant
Q33929567The influenza hemagglutinin precursor as an acid-sensitive probe of the biosynthetic pathway
Q38255435The insulin secretory granule
Q32121432The interaction of tributyllead with lysosomes from rat liver
Q73774547The interactions of trialkyltin compounds with lysosomes from rat liver
Q33930204The internalization of nerve growth factor by high-affinity receptors on pheochromocytoma PC12 cells.
Q53763485The intracellular controlled release from bioresponsive mesoporous silica with folate as both targeting and capping agent.
Q41469115The kinetic aspects of intracellular fluorescence labeling with TMA-DPH support the maturation model for endocytosis in L929 cells
Q38710979The liver and intracellular digestion: how liver cells eat!
Q36661989The lysosomal proenzyme receptor that binds procathepsin L to microsomal membranes at pH 5 is a 43-kDa integral membrane protein
Q36224120The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments
Q57960197The mannose 6-phosphate receptor and the biogenesis of lysosomes
Q40954759The non-antibiotic macrolide EM900 inhibits rhinovirus infection and cytokine production in human airway epithelial cells.
Q38035142The phagosome-lysosome membrane system and its regulation in Paramecium.
Q36687639The position of lysosomes within the cell determines their luminal pH
Q43915631The progenitor of ATP synthases was closely related to the current vacuolar H+-ATPase
Q36220522The propeptide of preprosomatostatin mediates intracellular transport and secretion of alpha-globin from mammalian cells
Q38185435The proton pump ATPase of lysosomes and related organelles of the vacuolar apparatus
Q33824729The road taken: past and future foundations of membrane traffic
Q26864223The role of TRPMLs in endolysosomal trafficking and function
Q33776753The role of the activated macrophage in clearing Listeria monocytogenes infection
Q36863973The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles
Q42608290The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin.
Q24290722The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif
Q51900688The transcription factor HNF1α regulates expression of chloride-proton exchanger ClC-5 in the renal proximal tubule
Q38731626The uptake and intracellular fate of PLGA nanoparticles in epithelial cells
Q36416690The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPase
Q27936889The yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle trafficking
Q37266848The yeast lysosome-like vacuole: endpoint and crossroads
Q33907147Theoretical considerations on the role of membrane potential in the regulation of endosomal pH
Q42694508Thermodynamic analysis of the increased stability of major histocompatibility complex class II molecule I-Ek complexed with an antigenic peptide at an acidic pH.
Q44919348Three-dimensional imaging of single nanotube molecule endocytosis on plasmonic substrates
Q39294022Toxicity mechanisms of amphotericin B and its neutralization by conjugation with arabinogalactan
Q37638812Trans-Golgi reticulum
Q40574579Transduction of skin-migrating dendritic cells by human adenovirus 5 occurs via an actin-dependent phagocytic pathway
Q28610251Transfer of free polymannose-type oligosaccharides from the cytosol to lysosomes in cultured human hepatocellular carcinoma HepG2 cells
Q41761028Transfer of zymosan (yeast cell walls) to the parasitophorous vacuoles of macrophages infected with Leishmania amazonensis
Q46600582Transformational process of the endosomal compartment in nephrocytes of Drosophila melanogaster
Q36217654Translocation and clustering of endosomes and lysosomes depends on microtubules
Q30537573Transmembrane protein OSTA-1 shapes sensory cilia morphology via regulation of intracellular membrane trafficking in C. elegans
Q41317185Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump.
Q27486207Transport of incoming influenza virus nucleocapsids into the nucleus
Q54610706Transport of residual endocytosed products into terminal lysosomes occurs slowly in rat liver endothelial cells.
Q50083508Transporting carriers for intracellular targeting delivery via non-endocytic uptake pathways.
Q44774840Triggering by ATP of product release by mucous granules of the land slug Ariolimax columbianus
Q40117268Tripartite polyionic complex (PIC) micelles as non-viral vectors for mesenchymal stem cell siRNA transfection
Q36559721Tripeptidyl-peptidase I in health and disease
Q41921451Truncated TrkB mediates the endocytosis and release of BDNF and neurotrophin-4/5 by rat astrocytes and schwann cells in vitro
Q37328046Tulobuterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells
Q34989667Tunable Bifunctional Silyl Ether Cross-Linkers for the Design of Acid-Sensitive Biomaterials
Q41355768Two threshold values of low pH block endocytosis at different stages.
Q39447357Two types of H+-ATPase are involved in the acidification of internal compartments in Trypanosoma cruzi
Q41744280Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils
Q38328811Tyrosine 67 in the epidermal growth factor-like domain of tissue-type plasminogen activator is important for clearance by a specific hepatic receptor
Q46348155Tyrphostin A8 stimulates a novel trafficking pathway of apically endocytosed transferrin through Rab11-enriched compartments in Caco-2 cells.
Q47894769Tyrphostin A9 and wortmannin perturb the Golgi complex and block proliferation of vascular smooth muscle cells
Q74501935Ultrastructural and cytochemical evaluation of sepsis-induced changes in the rat pulmonary intravascular mononuclear phagocytes
Q40040947Uncoating of human rhinovirus serotype 2 from late endosomes
Q42156561Uptake of denatured collagen into hepatic stellate cells: evidence for the involvement of urokinase plasminogen activator receptor-associated protein/Endo180.
Q33907871Use of the green fluorescent protein and its mutants in quantitative fluorescence microscopy
Q96174376Utilising magnetically isolated lysosomes for direct quantification of intralysosomal drug concentrations by LC-MS/MS analysis: An investigatory study with imipramine
Q30515861V-ATPase V1 sector is required for corpse clearance and neurotransmission in Caenorhabditis elegans
Q24301314V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway
Q35384317V-type ATPases. Introduction
Q43984455V-type H+-ATPase in the human eccrine sweat duct: immunolocalization and functional demonstration
Q27931900VMA12 encodes a yeast endoplasmic reticulum protein required for vacuolar H+-ATPase assembly
Q38872440Vaccine delivery by penetratin: mechanism of antigen presentation by dendritic cells
Q67898943Vacuolar Acidification and Bafilomycin-Sensitive Proton Translocating ATPase in Human Epidermal Langerhans Cells
Q41298430Vacuolar H(+)-ATPase: from mammals to yeast and back
Q28142699Vacuolar and plasma membrane proton-adenosinetriphosphatases
Q38260409Vacuolar proton pumps
Q32109561Vacuolar-type H+-ATPase regulates cytoplasmic pH in Toxoplasma gondii tachyzoites
Q33825601Vesicular stomatitis virus G protein acquires pH-independent fusion activity during transport in a polarized endometrial cell line
Q39868443Viral RNA modulates the acid sensitivity of foot-and-mouth disease virus capsids.
Q26750146Viral entry pathways: the example of common cold viruses
Q30275435Viral factors in influenza pandemic risk assessment.
Q38226881Virus entry into animal cells
Q77748464Visualization of actin dynamics during macropinocytosis and exocytosis
Q24681388Visualizing infection of individual influenza viruses
Q24619581Vma21p is a yeast membrane protein retained in the endoplasmic reticulum by a di-lysine motif and is required for the assembly of the vacuolar H(+)-ATPase complex
Q27936421Vma22p is a novel endoplasmic reticulum-associated protein required for assembly of the yeast vacuolar H(+)-ATPase complex
Q53518588Vps33B is required for delivery of endocytosed cargo to lysosomes.
Q34874744What's special about secretory lysosomes?
Q39436103YVO4:Eu3+ functionalized porous silica submicrospheres as delivery carriers of doxorubicin
Q34335302Yeast competence for exogenous DNA uptake: towards understanding its genetic component
Q40898883Yeast extracellular proteases
Q36234260Yolk platelets in Xenopus oocytes maintain an acidic internal pH which may be essential for sodium accumulation
Q34310701Zebrafish tyrosylprotein sulfotransferase: molecular cloning, expression, and functional characterization
Q39029155Zinc sulfide nanoparticles selectively induce cytotoxic and genotoxic effects on leukemic cells: involvement of reactive oxygen species and tumor necrosis factor alpha
Q24556620beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform
Q33635382cDNA sequence encoding the 16-kDa proteolipid of chromaffin granules implies gene duplication in the evolution of H+-ATPases
Q39578611fus-1, a pH shift mutant of Semliki Forest virus, acts by altering spike subunit interactions via a mutation in the E2 subunit
Q55234485pH Responsive Polymer Micelles Enhances Inhibitory Efficacy on Metastasis of Murine Breast Cancer Cells.
Q35430061pH and calcium dependence of hemolysis due to Rickettsia prowazekii: comparison with phospholipase activity.
Q46323059pH-Driven preparation of two related platinum(ii) complexes exhibiting distinct cytotoxic properties
Q60917799pH-Induced Folding of the Caspase-Cleaved Par-4 Tumor Suppressor: Evidence of Structure Outside of the Coiled Coil Domain
Q90669006pH-Responsive Artesunate Polymer Prodrugs with Enhanced Ablation Effect on Rodent Xenograft Colon Cancer
Q38695106pH-Sensitive stimulus-responsive nanocarriers for targeted delivery of therapeutic agents.
Q41142545pH-dependent processing of secretogranin II by the endopeptidase PC2 in isolated immature secretory granules.
Q36234623pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle
Q44924078pH-independent endocytic cycling of the chemokine receptor CCR5.
Q34317633pH-responsive NIR enhanced drug release from gold nanocages possesses high potency against cancer cells
Q37087260pH-responsive biodegradable assemblies containing tunable phenyl-substituted vinyl ethers for use as efficient gene delivery vehicles.
Q38168593pH-sensitive drug-delivery systems for tumor targeting
Q50527256pH-sensitive fluorescent sensors based on europium(III) complexes.
Q41930572pH-sensitive, cationic liposomes: a new synthetic virus-like vector

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