Hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis and its safety in pregnancy

scientific article published on 22 March 2011

Hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis and its safety in pregnancy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1517/14740338.2011.566555
P698PubMed publication ID21417950

P50authorWilbert S AronowQ67208280
P2093author name stringKirk Sperber
Julia Y Ash
Deborah L Shapiro
Chun Peng Chao
Crispin Abarientos
P2860cites workChloroquine enhances human CD8+ T cell responses against soluble antigens in vivoQ27485211
Toll-like receptorsQ27860671
Anti-inflammatory and immunosuppressive drugs and reproductionQ28218219
Effect of hydroxychloroquine on the survival of patients with systemic lupus erythematosus: data from LUMINA, a multiethnic US cohort (LUMINA L)Q31107094
Hydroxychloroquine in lupus pregnancyQ33373145
Systematic review of hydroxychloroquine use in pregnant patients with autoimmune diseasesQ33445361
Protective effect of hydroxychloroquine on renal damage in patients with lupus nephritis: LXV, data from a multiethnic US cohortQ33455990
Lupus pregnancy. Case-control prospective study demonstrating absence of lupus exacerbation during or after pregnancyQ33478819
Hydroxychloroquine and lupus pregnancy: review of a series of 36 casesQ33579097
Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.Q33731760
Effects of weakly basic amines on proteolytic processing and terminal glycosylation of secretory proteins in cultured rat hepatocytesQ34180904
Antimalarial drugs in systemic lupus erythematosus: use in pregnancyQ34458596
Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agentsQ34556950
Lysosomal sequestration of amine-containing drugs: analysis and therapeutic implicationsQ34583259
Hydroxychloroquine and chloroquine retinopathy: screening for drug toxicityQ34626216
IL-17 and the Th17 lineage in systemic lupus erythematosusQ34807773
Pharmacogenetics of disease-modifying anti-rheumatic drugsQ35761889
Safety of hydroxychloroquine in pregnant patients with connective tissue diseases. Review of the literatureQ36049718
Influence of hydroxychloroquine on the bioavailability of oral metoprololQ36055442
Antirheumatic drugs in pregnancy and lactationQ36272347
Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cellsQ36275163
Chloroquine affects biosynthesis of Ia molecules by inhibiting dissociation of invariant (gamma) chains from alpha-beta dimers in B cellsQ36350981
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.Q36403678
Disease-modifying antirheumatic drugs in pregnancy: current status and implications for the futureQ36592626
The dominant self and the cryptic self: shaping the autoreactive T-cell repertoireQ36676063
Ocular adverse effects associated with systemic medications : recognition and managementQ36702081
Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic reviewQ37356697
Management of RA medications in pregnant patientsQ37511730
Methotrexate nodulosisQ38527495
Chloroquine, quinine, procaine, quinidine, tricyclic antidepressants, and methylxanthines as prostaglandin agonists and antagonistsQ39409324
Acidification of the endocytic and exocytic pathwaysQ39459758
Inhibition of mitogen-activated protein kinase signaling by chloroquineQ40733870
The antiphospholipid syndrome and SLE: is there a clue in the link between complement and coagulation?Q40951725
Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recyclingQ41337499
Capture and processing of exogenous antigens for presentation on MHC molecules.Q41464375
Antimalarial drugs in the treatment of rheumatological diseasesQ41560764
Systemic lupus erythematosus in three ethnic groups: XVI. Association of hydroxychloroquine use with reduced risk of damage accrualQ41912319
Follow-up of infants exposed to hydroxychloroquine given to mothers during pregnancy and lactationQ41913288
Multifocal electroretinographic evaluation of long-term hydroxychloroquine usersQ41913752
Safety of hydroxychloroquine in pregnant patients with connective tissue diseases: A study of one hundred thirty‐three cases compared with a control groupQ41915008
The incidence of irreversible retinal toxicity in patients treated with hydroxychloroquine: a reappraisalQ41915573
Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications: results of a two-year, randomized, double-blind, placebo-controlled trialQ41917264
Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritisQ41917273
Evidence of transplacental passage of hydroxychloroquine in humansQ41917690
Hydroxychloroquine (HCQ) in lupus pregnancy: double-blind and placebo-controlled study.Q41919391
Antimalarial drugs for rheumatoid arthritisQ41920359
Chloroquine interferes with lipopolysaccharide-induced TNF-alpha gene expression by a nonlysosomotropic mechanismQ41921412
Dose-loading with hydroxychloroquine improves the rate of response in early, active rheumatoid arthritis: a randomized, double-blind six-week trial with eighteen-week extensionQ41924609
Antimalarial therapy for lupus erythematosus: an apparent advantage of quinacrineQ41925679
Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medicationsQ41930813
Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosusQ41935707
Previous antimalarial therapy in patients diagnosed with lupus nephritis: influence on outcomes and survivalQ41941085
Pregnancy outcome following first trimester exposure to chloroquineQ41942091
Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosusQ41942520
Cholesterol-lowering effect of hydroxychloroquine in patients with rheumatic disease: reversal of deleterious effects of steroids on lipidsQ41943371
Low blood concentration of hydroxychloroquine is a marker for and predictor of disease exacerbations in patients with systemic lupus erythematosusQ41944460
Mode of action of hydroxychloroquine in RA-evidence of an inhibitory effect on toll-like receptor signalingQ41944676
Chloroquine treatment influences proinflammatory cytokine levels in systemic lupus erythematosus patientsQ41945144
Hydroxychloroquine potentiates Fas-mediated apoptosis of rheumatoid synoviocytes.Q41945241
Multifocal electroretinographic changes in patients receiving hydroxychloroquine therapyQ41946375
Successful Desensitization for Hydroxychloroquine AnaphylaxisQ42920228
Effect of antimalarials on thrombosis and survival in patients with systemic lupus erythematosus.Q43417859
Ocular toxicity and antenatal exposure to chloroquine or hydroxychloroquine for rheumatic diseasesQ43743058
Antimalarial agents in pregnancyQ45712596
RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3.Q46687345
New insights into the antiviral effects of chloroquine.Q46913485
Treatment of rheumatoid arthritisQ56060521
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectsystemic lupus erythematosusQ1485
rheumatoid arthritisQ187255
lupus erythematosusQ188297
hydroxychloroquineQ421094
P304page(s)705-714
P577publication date2011-03-22
P1433published inExpert Opinion on Drug SafetyQ5421206
P1476titleHydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis and its safety in pregnancy
P478volume10