Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo

scientific article (publication date: 19 September 2005)

Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.20051106
P932PMC publication ID2212941
P698PubMed publication ID16157687
P5875ResearchGate publication ID7604581

P50authorMargherita DoriaQ40745487
Mario MondelliQ56480714
P2093author name stringCaroline Molette
Daniele Accapezzato
Maria Rosaria Torrisi
Marino Paroli
Tiziana Donato
Vincenzo Barnaba
Vincenzo Visco
Vittorio Francavilla
P2860cites workAntigen presentation and T cell stimulation by dendritic cellsQ22255632
Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cellsQ24653129
Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial productsQ24678867
Significance of the immune response to a major, conformational B-cell epitope on the hepatitis C virus NS3 region defined by a human monoclonal antibodyQ27485923
Dendritic cells and the control of immunityQ27860918
A human homologue of the Drosophila Toll protein signals activation of adaptive immunityQ28131769
Of mice and not men: differences between mouse and human immunologyQ28246229
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alphaQ28251443
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cellsQ28506676
Phagosomes are competent organelles for antigen cross-presentationQ28591811
Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytesQ28609747
Visualizing dendritic cell networks in vivoQ29616233
Dendritic cells: specialized and regulated antigen processing machinesQ29617085
Tolerogenic dendritic cellsQ29618755
Molecular identification of a danger signal that alerts the immune system to dying cellsQ29619497
Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccinesQ33683185
Natural adjuvants: endogenous activators of dendritic cellsQ33878894
Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assayQ33903838
Cross-presentation, dendritic cells, tolerance and immunityQ34178099
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Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cellsQ36274042
Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cellsQ36275163
Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophagesQ36327656
Influenza virus hemagglutinin-specific cytotoxic T cell response induced by polypeptide produced in Escherichia coliQ36350548
Dendritic cells are the principal cells in mouse spleen bearing immunogenic fragments of foreign proteinsQ36352027
Human T cell response to the surface antigen of hepatitis B virus (HBsAg). Endosomal and nonendosomal processing pathways are accessible to both endogenous and exogenous antigenQ36355057
Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 primingQ80975562
Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosisQ36365348
Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalizationQ36367948
The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and in vivoQ36370304
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cellsQ36375909
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell toleranceQ36376611
Rat spleen dendritic cells express natural killer cell receptor protein 1 (NKR-P1) and have cytotoxic activity to select targets via a Ca2+-dependent mechanismQ36380421
Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cellsQ36401207
Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathwaysQ36404658
CD4 and major histocompatibility complex class I downregulation by the human immunodeficiency virus type 1 nef protein in pediatric AIDS progressionQ36538938
Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigensQ36689895
Cellular protein is the source of cross-priming antigen in vivoQ36853548
Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines.Q37424192
Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells.Q40481734
CD8+ T cell cross-priming via transfer of proteasome substratesQ40551130
Efficient scavenger receptor-mediated uptake and cross-presentation of negatively charged soluble antigens by dendritic cellsQ40555227
Apoptotic cells overexpress vinculin and induce vinculin-specific cytotoxic T-cell cross-primingQ40795464
Purified influenza virus nucleoprotein protects mice from lethal infectionQ40799908
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLsQ41057373
Cloned dendritic cells can present exogenous antigens on both MHC class I and class II moleculesQ41120866
Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages.Q41262004
A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I moleculesQ41380874
Capture and processing of exogenous antigens for presentation on MHC molecules.Q41464375
Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatusQ41483433
Presentation of exogenous antigen with class I major histocompatibility complex moleculesQ41724565
Selective killing of hepatitis B envelope antigen-specific B cells by class I-restricted, exogenous antigen-specific T lymphocytesQ41733978
Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivoQ41872431
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.Q41915692
Chloroquine reduces whole body proteolysis in humansQ41934971
Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanismsQ42982934
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune diseaseQ44285977
Antigen recognition. Class discrimination in the world of immunologyQ44582156
Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domainQ44623197
Differential lysosomal proteolysis in antigen-presenting cells determines antigen fateQ45345585
Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophagesQ45345587
Toll-like receptor 3 promotes cross-priming to virus-infected cells.Q45511446
Immunization with soluble hepatitis B virus surface protein elicits murine H-2 class I-restricted CD8+ cytotoxic T lymphocyte responses in vivoQ45776645
Flow analysis of MHC molecules and other membrane proteins in isolated phagosomesQ47815880
Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC moleculesQ50146397
Phagocytic processing of bacterial antigens for class I MHC presentation to T cellsQ50167043
Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cellsQ50335818
Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cellsQ50335820
Enhanced Dendritic Cell Antigen Capture via Toll-Like Receptor-Induced Actin RemodelingQ57204114
Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunityQ58862024
Class I MHC-restricted cytotoxic T lymphocyte recognition of cells infected with human cytomegalovirus does not require endogenous viral gene expressionQ67687100
Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cellsQ67902824
Brefeldin A specifically inhibits presentation of protein antigens to cytotoxic T lymphocytesQ69073408
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectchloroquineQ422438
P304page(s)817-28
P577publication date2005-09-19
P1433published inJournal of Experimental MedicineQ3186912
P1476titleChloroquine enhances human CD8+ T cell responses against soluble antigens in vivo
P478volume202

Reverse relations

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