Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation

scientific article published on 8 April 2013

Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.20121251
P932PMC publication ID3646496
P698PubMed publication ID23569326
P5875ResearchGate publication ID236140747

P50authorAnna Smed-SörensenQ88257244
P2093author name stringNorihiro Nakamura
Ira Mellman
Peter Lauer
Lélia Delamarre
Cécile Chalouni
Tibor Keler
Bithi Chatterjee
Richard Vandlen
Dirk Brockstedt
Byoung-Chul Lee
Lillian Cohn
Filipp Esselborn
P2860cites workSelective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subsetQ24652686
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypesQ24682603
Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivoQ27485211
Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell ImmunityQ27489852
Dendritic cells and the control of immunityQ27860918
Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cellsQ28119175
BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral bloodQ28138201
Autoimmunity in MFG-E8-deficient mice is associated with altered trafficking and enhanced cross-presentation of apoptotic cell antigensQ28388910
Differential antigen processing by dendritic cell subsets in vivoQ29615177
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivoQ30080006
Monocyte-Derived Dendritic Cells Exhibit Increased Levels of Lysosomal Proteolysis as Compared to Other Human Dendritic Cell PopulationsQ33651251
Differential susceptibility to human immunodeficiency virus type 1 infection of myeloid and plasmacytoid dendritic cellsQ33884007
Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens.Q33902330
The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cellsQ33902379
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cellsQ33902421
CD27 is required for generation and long-term maintenance of T cell immunityQ33924191
Cell biology of antigen processing in vitro and in vivoQ33985828
Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cellsQ34192846
Regulation of T cell immunity by dendritic cellsQ34339191
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.Q34573130
Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation.Q34623431
Plasmacytoid dendritic cells control T-cell response to chronic viral infection.Q35779317
Characterization of resident and migratory dendritic cells in human lymph nodesQ35894149
The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected miceQ35913706
Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammationQ35946105
A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo.Q36229330
Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profilingQ36673501
KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunityQ36964813
NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells.Q37002001
Antigen-presentation properties of plasmacytoid dendritic cellsQ37272231
Inflammatory signals in dendritic cell activation and the induction of adaptive immunityQ37361473
Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentationQ37363754
Dendritic cell subsets in primary and secondary T cell responses at body surfacesQ37633373
Intracellular mechanisms of antigen cross presentation in dendritic cellsQ37695674
The CD8+ dendritic cell subsetQ37700814
Comparative genomics as a tool to reveal functional equivalences between human and mouse dendritic cell subsetsQ37700838
A modular and combinatorial view of the antigen cross-presentation pathway in dendritic cells.Q37903403
Protein-mediated membrane fusionQ38648025
DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissuesQ39374974
Antibody-targeted NY-ESO-1 to mannose receptor or DEC-205 in vitro elicits dual human CD8+ and CD4+ T cell responses with broad antigen specificityQ39621141
Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cellsQ40952120
Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent mannerQ41164914
Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytesQ41578289
Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virusQ41913203
Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturationQ42861996
Effects of low pH on influenza virus. Activation and inactivation of the membrane fusion capacity of the hemagglutininQ45829893
The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cellsQ46071205
Introduction of soluble protein into the class I pathway of antigen processing and presentationQ46305448
Developmental control of endocytosis in dendritic cells by Cdc42.Q50119612
The inflammatory cytokine, GM-CSF, alters the developmental outcome of murine dendritic cells.Q50795170
Cutting Edge: TLR-Dependent viral recognition along with type I IFN positive feedback signaling masks the requirement of viral replication for IFN-{alpha} production in plasmacytoid dendritic cells.Q51758901
Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation.Q51765801
Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status.Q51869621
NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic CellsQ58007061
The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cellsQ58619899
The Acquisition of Antigen Cross-Presentation Function by Newly Formed Dendritic CellsQ58757859
Differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cellsQ81375587
Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activationQ84547662
Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cellsQ84569562
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
P304page(s)1049-1063
P577publication date2013-04-08
P1433published inJournal of Experimental MedicineQ3186912
P1476titleAntigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation
P478volume210

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