Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling

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Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling is …
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scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2013.00259
P932PMC publication ID3756424
P698PubMed publication ID24009611
P5875ResearchGate publication ID256452829

P2093author name stringRalf Fliegert
Andreas H. Guse
Insa M. A. Ernst
P2860cites workADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homologyQ24291275
Orai1 is an essential pore subunit of the CRAC channelQ24300383
mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic stateQ24315101
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signalingQ24316454
NAADP mobilizes calcium from acidic organelles through two-pore channelsQ24318546
CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entryQ24322017
Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin eggQ24600390
Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cellsQ24600457
TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltrationQ24644998
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymeraseQ24671634
Cloning and characterization of a new member of the Nudix hydrolases from human and mouseQ28118721
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cellsQ28138792
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell deathQ28216181
NAD kinase levels control the NADPH concentration in human cellsQ28248607
Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activitiesQ28253562
Capacitative calcium entry: from concept to moleculesQ28258579
Linking NAADP to ion channel activity: a unifying hypothesisQ28265293
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomesQ28276964
Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activityQ28284283
Pyridine nucleotide metabolites stimulate calcium release from sea urchin egg microsomes desensitized to inositol trisphosphateQ28299232
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel functionQ28305026
The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal storesQ28585336
Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system.Q30495158
The making of a leukocyte receptor: origin, genes and regulation of human CD38 and related molecules.Q33941855
CD38 in T- and B-cell functions.Q33941889
Regulation of poly(ADP-ribose) metabolism by poly(ADP-ribose) glycohydrolase: where and when?Q33986845
The role of TRP channels in oxidative stress-induced cell deathQ33995721
Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38.Q34060896
Knock-down of the type 3 ryanodine receptor impairs sustained Ca2+ signaling via the T cell receptor/CD3 complexQ34152329
NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase.Q34158627
Rat liver nucleoside diphosphosugar or diphosphoalcohol pyrophosphatases different from nucleotide pyrophosphatase or phosphodiesterase I: substrate specificities of Mg(2+)-and/or Mn(2+)-dependent hydrolases acting on ADP-ribose.Q34315792
TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammationQ34451015
A transport mechanism for NAADP in a rat basophilic cell lineQ34483087
A cell permeable NPE caged ADP-ribose for studying TRPM2Q34510656
IP3 receptor/Ca2+ channel: from discovery to new signaling conceptsQ34662801
Covalent modification of proteins by metabolites of NAD+.Q35023440
CD38: a multi-lineage cell activation molecule with a split personalityQ35713128
The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseasesQ35951096
Regulation of transcription factor NFAT by ADP-ribosylationQ36540217
TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytesQ37118266
NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonistQ37229250
Metabolic checkpoints in activated T cellsQ38044664
The membrane-bound enzyme CD38 exists in two opposing orientationsQ39280765
Ca2+ entry induced by cyclic ADP-ribose in intact T-lymphocytesQ39442139
8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonistQ39843320
The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytesQ39965490
Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophilsQ39969317
Determination of intracellular concentrations of the TRPM2 agonist ADP-ribose by reversed-phase HPLC.Q40416133
TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in miceQ40536276
Immunocyte Ca2+ influx system mediated by LTRPC2.Q40785446
Quantification of intracellular levels of cyclic ADP-ribose by high-performance liquid chromatography.Q41037210
Non-radioactive, isomer-specific inositol phosphate mass determinations: high-performance liquid chromatography-micro-metal-dye detection strongly improves speed and sensitivity of analyses from cells and micro-enzyme assaysQ41281507
Characterization of cyclic adenosine diphosphate-ribose-induced Ca2+ release in T lymphocyte cell linesQ41291197
ADP-ribose in glycation and glycoxidation reactionsQ41507638
The lymphocyte surface antigen CD38 acts as a nicotinamide adenine dinucleotide glycohydrolase in human T lymphocytesQ41510770
D-myo-inositol 1,3,4,5-tetrakisphosphate releases Ca2+ from crude microsomes and enriched vesicular plasma membranes, but not from intracellular stores of permeabilized T-lymphocytes and monocytesQ41591137
The CD38/cyclic ADP-ribose system: a topological paradoxQ41686792
Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.Q41923686
Free ADP-ribose in human erythrocytes: pathways of intra-erythrocytic conversion and non-enzymic binding to membrane proteinsQ42073716
NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killingQ42418448
NAADP: a universal Ca2+ triggerQ42444377
NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area.Q42489294
NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cellsQ42497166
Rat liver mitochondrial ADP-ribose pyrophosphatase in the matrix space with low Km for free ADP-riboseQ42834105
NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptorsQ42917771
Nicotinic acid adenine dinucleotide phosphate (NAADP(+)) is an essential regulator of T-lymphocyte Ca(2+)-signalingQ42920018
Nicotinic acid-adenine dinucleotide phosphate activates the skeletal muscle ryanodine receptorQ43002260
Transient tyrosine phosphorylation of human ryanodine receptor upon T cell stimulationQ43683610
ADP-ribose stimulates the calcium release channel RyR1 in skeletal muscle of rat.Q44122938
Amplification and propagation of pacemaker Ca2+ signals by cyclic ADP-ribose and the type 3 ryanodine receptor in T cellsQ44822106
Lysosome-sarcoplasmic reticulum junctions. A trigger zone for calcium signaling by nicotinic acid adenine dinucleotide phosphate and endothelin-1.Q45032464
Ca2+ release via ryanodine receptors and Ca2+ entry: major mechanisms in NAADP-mediated Ca2+ signaling in T-lymphocytesQ45036866
Circulating HIV-specific CD8+ cytotoxic T cells express CD38 and HLA-DR antigens.Q46200764
Functional ryanodine receptor expression is required for NAADP-mediated local Ca2+ signaling in T-lymphocytes.Q46387081
Activation of T cell calcium influx by the second messenger ADP-riboseQ46827120
Regulation of NFAT by poly(ADP-ribose) polymerase activity in T cells.Q46851148
From research tool to routine test: CD38 monitoring in HIV patientsQ47863655
NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclasesQ50336037
NAD glycohydrolase activities and ADP-ribose uptake in erythrocytes from normal subjects and cancer patients.Q50487706
NAADP mobilizes calcium from the endoplasmic reticular Ca(2+) store in T-lymphocytes.Q50698075
The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP.Q50746326
Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose.Q53935821
Function of NAD glycohydrolase in ADP-ribose uptake from NAD by human erythrocytesQ70469008
ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium-mobilizing metabolite from NADPQ70808763
Functional visualization of the separate but interacting calcium stores sensitive to NAADP and cyclic ADP-riboseQ73198872
CD38: a NAADP degrading enzymeQ82153078
Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytesQ83056883
Second messenger function of nicotinic acid adenine dinucleotide phosphate revealed by an improved enzymatic cycling assayQ83181175
P407language of work or nameEnglishQ1860
P304page(s)259
P577publication date2013-01-01
P1433published inFrontiers in ImmunologyQ27723748
P1476titleAdenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling
P478volume4

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cites work (P2860)
Q33898222Age dependent differences in the kinetics of γδ T cells after influenza vaccination
Q36731541CD38 Expression in a Subset of Memory T Cells Is Independent of Cell Cycling as a Correlate of HIV Disease Progression
Q35621599CD38 is expressed on inflammatory cells of the intestine and promotes intestinal inflammation
Q38875103Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules.
Q36769825Ion channels in innate and adaptive immunity
Q83229106Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel
Q27313411Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase
Q39195646Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin
Q37365767The regulation of calcium homeostasis in T lymphocytes

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