| scholarly article | Q13442814 |
| P50 | author | Antony Giuseppe Galione | Q24005240 |
| Stuart J. Conway | Q40116703 | ||
| Vincenzo Cerundolo | Q40619109 | ||
| P2093 | author name string | Grant C Churchill | |
| Anthony J Morgan | |||
| John Parrington | |||
| Lianne C Davis | |||
| Megan N Stanton-Humphreys | |||
| Ji-Li Chen | |||
| Eugene Shenderov | |||
| Duncan Bloor-Young | |||
| Charlotte M Snead | |||
| P2860 | cites work | Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling | Q24316454 |
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| Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells | Q28138792 | ||
| The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores | Q28585336 | ||
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| Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells | Q30506037 | ||
| 2-aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release. | Q34142358 | ||
| NAADP receptors | Q34147867 | ||
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| Second messenger signaling: multiple receptors for NAADP. | Q39825378 | ||
| Protein kinase C delta localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity | Q39938302 | ||
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| Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role | Q40213772 | ||
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| L is for lytic granules: lysosomes that kill | Q41734072 | ||
| Ryanodine receptor type I and nicotinic acid adenine dinucleotide phosphate receptors mediate Ca2+ release from insulin-containing vesicles in living pancreatic beta-cells (MIN6). | Q44285317 | ||
| Functional ryanodine receptor expression is required for NAADP-mediated local Ca2+ signaling in T-lymphocytes. | Q46387081 | ||
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| Requirements for triggering of lysis by cytolytic T lymphocyte clones | Q70030264 | ||
| Cyclopiazonic acid inhibition of the Ca2+-transport ATPase in rat skeletal muscle sarcoplasmic reticulum vesicles | Q70047829 | ||
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| NAADP as an intracellular messenger regulating lysosomal calcium-release channels | Q82669208 | ||
| Second messenger function of nicotinic acid adenine dinucleotide phosphate revealed by an improved enzymatic cycling assay | Q83181175 | ||
| P4510 | describes a project that uses | Jurkat 1G4 | Q54899129 |
| P433 | issue | 24 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | exocytosis | Q323426 |
| cell line | Q21014462 | ||
| P304 | page(s) | 2331-2337 | |
| P577 | publication date | 2012-11-21 | |
| P1433 | published in | Current Biology | Q1144851 |
| P1476 | title | NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing | |
| P478 | volume | 22 |
| Q24310969 | A THEMIS:SHP1 complex promotes T-cell survival |
| Q35444009 | ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells |
| Q41072178 | Activity-Dependent Exocytosis of Lysosomes Regulates the Structural Plasticity of Dendritic Spines. |
| Q27025044 | Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling |
| Q37429710 | Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1. |
| Q28286984 | Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organelles |
| Q36731541 | CD38 Expression in a Subset of Memory T Cells Is Independent of Cell Cycling as a Correlate of HIV Disease Progression |
| Q38682962 | Ca2+ Microdomains in T-Lymphocytes |
| Q41467010 | Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation |
| Q38620889 | Calcium signaling in membrane repair |
| Q90950194 | Calcium signalling in T cells |
| Q26852411 | Cell biological steps and checkpoints in accessing NK cell cytotoxicity |
| Q40769182 | Cytolytic granules supply Ca(2+) for their own exocytosis via NAADP and resident two-pore channels |
| Q57810585 | Divergent TCR-Initiated Calcium Signals Govern Recruitment versus Activation of Human Alloreactive Effector Memory T Cells by Endothelial Cells |
| Q24307004 | Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition |
| Q61812437 | Endolysosomal Ca Signalling and Cancer Hallmarks: Two-Pore Channels on the Move, TRPML1 Lags Behind! |
| Q87283451 | Exploring the biophysical evidence that mammalian two-pore channels are NAADP-activated calcium-permeable channels |
| Q28260464 | Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells |
| Q34483905 | Function and dysfunction of two-pore channels |
| Q64260975 | GPN does not release lysosomal Ca but evokes Ca release from the ER by increasing the cytosolic pH independently of cathepsin C |
| Q30837702 | GTPase of the Immune-Associated Nucleotide Protein 5 Regulates the Lysosomal Calcium Compartment in T Lymphocytes |
| Q90403272 | HIV Disease Progression: Overexpression of the Ectoenzyme CD38 as a Contributory Factor? |
| Q24339389 | Hax-1 identified as a two-pore channel (TPC)-binding protein |
| Q30835214 | High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart |
| Q93350408 | Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca2+ signaling |
| Q36802183 | Immune dysfunction in Niemann-Pick disease type C. |
| Q88320325 | Integration of nicotinic acid adenine dinucleotide phosphate (NAADP)-dependent calcium signalling |
| Q34462083 | Lysosomal physiology |
| Q40164611 | Mechanisms of Filovirus Entry. |
| Q92641372 | NAADP Receptors |
| Q37635358 | NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa |
| Q40050825 | Ned-19 inhibition of parasite growth and multiplication suggests a role for NAADP mediated signalling in the asexual development of Plasmodium falciparum |
| Q93133118 | Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Induces Intracellular Ca2+ Release through the Two-Pore Channel TPC1 in Metastatic Colorectal Cancer Cells |
| Q34483914 | Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells. |
| Q36744512 | Nicotinic Acid Adenine Dinucleotide Phosphate Plays a Critical Role in Naive and Effector Murine T Cells but Not Natural Regulatory T Cells |
| Q38856011 | Origins of the cytolytic synapse |
| Q38872878 | Preferential Coupling of the NAADP Pathway to Exocytosis in T-Cells. |
| Q39515801 | Questioning regulation of two-pore channels by NAADP |
| Q61805390 | Remodeling of secretory lysosomes during education tunes functional potential in NK cells |
| Q52668321 | Signals Controlling Lytic Granule Polarization at the Cytotoxic Immune Synapse. |
| Q89498991 | TPC2 mediates autophagy progression and extracellular vesicle secretion in cancer cells |
| Q27306330 | TPC2 mediates new mechanisms of platelet dense granule membrane dynamics through regulation of Ca2+ release |
| Q28262391 | TPC: the NAADP discovery channel? |
| Q50746326 | The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP. |
| Q34552502 | The human two-pore channel 1 is modulated by cytosolic and luminal calcium. |
| Q38151847 | The role of the cytoskeleton at the immunological synapse |
| Q41820235 | Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH. |
| Q34776238 | Two pore channel 2 differentially modulates neural differentiation of mouse embryonic stem cells |
| Q33703425 | Two-Pore Channels and Parkinson's Disease: Where's the Link? |
| Q34531617 | Two-Pore Channels: Lessons from Mutant Mouse Models |
| Q43099248 | Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart |
| Q36125120 | Two-pore channel 1 interacts with citron kinase, regulating completion of cytokinesis |
| Q37613806 | Two-pore channels (TPCs): Novel voltage-gated ion channels with pleiotropic functions |
| Q28302766 | Two-pore channels (TPCs): current controversies |
| Q27346606 | Two-pore channels function in calcium regulation in sea star oocytes and embryos |
| Q34480730 | VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling |
| Q39412197 | cAMP-dependent recruitment of acidic organelles for Ca2+ signaling in the salivary gland |
| Q54899129 | Jurkat 1G4 | described by source | P1343 |
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