Questioning regulation of two-pore channels by NAADP

scientific article published on June 2013

Questioning regulation of two-pore channels by NAADP is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1166/MSR.2013.1027
P932PMC publication ID4018199
P698PubMed publication ID24829847

P2093author name stringSandip Patel
Jonathan S Marchant
P2860cites workCyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels.Q34684877
Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.Q34685254
Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channelsQ35067713
Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signalingQ36217193
The role of calcium and other ions in sorting and delivery in the late endocytic pathwayQ36979614
TRPMLs: in sickness and in healthQ37216903
Molecular mechanisms of endolysosomal Ca2+ signalling in health and diseaseQ37944859
NAADP on targetQ37997679
An N-terminal dileucine motif directs two-pore channels to the tonoplast of plant cellsQ39366914
Acidic NAADP-releasable Ca(2+) compartments in the megakaryoblastic cell line MEG01.Q39538658
Second messenger signaling: multiple receptors for NAADP.Q39825378
Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium releaseQ41822869
Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive poolQ41865560
Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytesQ41891896
Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhance the sensitivity of NAADP receptors for their ligandQ42254591
NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killingQ42418448
NAADP: a universal Ca2+ triggerQ42444377
The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organellesQ42919564
The Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex?Q42940716
Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signalsQ42959504
A putative two pore channel AtTPC1 mediates Ca(2+) flux in Arabidopsis leaf cellsQ43751036
NAADP on the up in pancreatic beta cells-a sweet message?Q44419707
The vacuolar Ca2+-activated channel TPC1 regulates germination and stomatal movementQ48146660
The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP.Q50746326
Triggering of Ca2+ signals by NAADP-gated two-pore channels: a role for membrane contact sites?Q51823379
Functional visualization of the separate but interacting calcium stores sensitive to NAADP and cyclic ADP-riboseQ73198872
NAADP as an intracellular messenger regulating lysosomal calcium-release channelsQ82669208
mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic stateQ24315101
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signalingQ24316454
NAADP mobilizes calcium from acidic organelles through two-pore channelsQ24318546
Two-pore channels form homo- and heterodimersQ24337485
Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin eggQ24600390
Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cellsQ24600457
TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+Q24621022
Identification of a chemical probe for NAADP by virtual screeningQ24654132
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cellsQ28138792
Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channelsQ28141035
NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggsQ28216586
Domain assembly of NAADP-gated two-pore channelsQ28250269
Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1Q28264441
Linking NAADP to ion channel activity: a unifying hypothesisQ28265293
An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organellesQ28265825
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomesQ28276964
Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signalingQ28277133
Unique inactivation properties of NAADP-sensitive Ca2+ releaseQ28281723
Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomesQ28283147
Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organellesQ28286984
An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signalsQ28294394
A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-riboseQ28306365
Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of ratsQ28569468
The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal storesQ28585336
The plant vacuole: emitter and receiver of calcium signalsQ30318457
Lysosomes shape Ins(1,4,5)P3-evoked Ca2+ signals by selectively sequestering Ca2+ released from the endoplasmic reticulum.Q30537868
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal traffickingQ33816664
Mucolipins: Intracellular TRPML1-3 channelsQ33838349
Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signalsQ34065665
Coordination of Ca2+ signalling by NAADP.Q34336886
P433issue2
P304page(s)113-119
P577publication date2013-06-01
P1433published inMessenger (Los Angeles, Calif. : Print)Q27724829
P1476titleQuestioning regulation of two-pore channels by NAADP
P478volume2

Reverse relations

cites work (P2860)
Q38969543Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes
Q36536361Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology
Q42255446Connecting Ca2+ and lysosomes to Parkinson disease
Q42257818Deviant lysosomal Ca2+ signalling in neurodegeneration. An introduction
Q87283451Exploring the biophysical evidence that mammalian two-pore channels are NAADP-activated calcium-permeable channels
Q28260464Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells
Q41880567Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore.
Q58609396Mining of Ebola virus entry inhibitors identifies approved drugs as two-pore channel pore blockers
Q47141627NAADP-evoked Ca2+ signals through two-pore channel-1 require arginine residues in the first S4-S5 linker
Q34483914Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.
Q38844674Poring over two-pore channel pore mutants
Q38872878Preferential Coupling of the NAADP Pathway to Exocytosis in T-Cells.
Q42596069TPC1 Knockout Knocks Out TPC1.
Q34583526The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation
Q58615503The protein interaction networks of mucolipins and two-pore channels
Q37613806Two-pore channels (TPCs): Novel voltage-gated ion channels with pleiotropic functions
Q28302766Two-pore channels (TPCs): current controversies
Q54215446Two-pore channels and disease.
Q28085768Two-pore channels at the intersection of endolysosomal membrane traffic

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