| P2093 | author name string | Shmuel Muallem | |
| | Michela Mazzon | |
| | Sandip Patel | |
| | Yu Yuan | |
| | Mark Marsh | |
| | Bethan S Kilpatrick | |
| | Elizabeth Yates | |
| | Archana Jha | |
| | Xavier Chee | |
| | Taufiq Rahman | |
| | Christopher J Penny | |
| | Kristin Vassileva | |
| P2860 | cites work | Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition | Q24307004 |
| | Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling | Q24316454 |
| | NAADP mobilizes calcium from acidic organelles through two-pore channels | Q24318546 |
| | Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection | Q24329155 |
| | Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg | Q24600390 |
| | Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells | Q24600457 |
| | TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+ | Q24621022 |
| | Identification of a chemical probe for NAADP by virtual screening | Q24654132 |
| | Pharmacological properties of the Ca2+-release mechanism sensitive to NAADP in the sea urchin egg | Q24672945 |
| | Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes | Q27321283 |
| | AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading | Q27860652 |
| | Two-pore channels at the intersection of endolysosomal membrane traffic | Q28085768 |
| | NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs | Q28216586 |
| | High susceptibility to fatty liver disease in two-pore channel 2-deficient mice | Q28246421 |
| | Domain assembly of NAADP-gated two-pore channels | Q28250269 |
| | Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells | Q28260464 |
| | Linking NAADP to ion channel activity: a unifying hypothesis | Q28265293 |
| | Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana | Q28271341 |
| | Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana | Q28274013 |
| | TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes | Q28276964 |
| | Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling | Q28277133 |
| | siRNA screen for genes that affect Junín virus entry uncovers voltage-gated calcium channels as a therapeutic target | Q39091684 |
| | Binding of trifluoperazine to the calcium-dependent activator of cyclic nucleotide phosphodiesterase | Q39156577 |
| | TPC1 has two variant isoforms, and their removal has different effects on endo-lysosomal functions compared to loss of TPC2. | Q39271543 |
| | Questioning regulation of two-pore channels by NAADP | Q39515801 |
| | Clustering of InsP3 receptors by InsP3 retunes their regulation by InsP3 and Ca2+. | Q39863840 |
| | Graded recruitment and inactivation of single InsP3 receptor Ca2+-release channels: implications for quantal [corrected] Ca2+release | Q40286473 |
| | Tuning the ion selectivity of two-pore channels | Q41779299 |
| | Dihydropyridine action on voltage-dependent potassium channels expressed in Xenopus oocytes | Q41984324 |
| | Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed | Q42008231 |
| | An Endosomal NAADP-Sensitive Two-Pore Ca2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling | Q42133849 |
| | Isolated pores dissected from human two-pore channel 2 are functional | Q42354590 |
| | The Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex? | Q42940716 |
| | Modulation of NAADP (nicotinic acid-adenine dinucleotide phosphate) receptors by K+ ions: evidence for multiple NAADP receptor conformations | Q43003228 |
| | NAADP-evoked Ca2+ signals through two-pore channel-1 require arginine residues in the first S4-S5 linker | Q47141627 |
| | e-Drug3D: 3D structure collections dedicated to drug repurposing and fragment-based drug design. | Q47993030 |
| | Two-Pore Channel Function Is Crucial for the Migration of Invasive Cancer Cells. | Q51177236 |
| | Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel. | Q52644779 |
| | Two-pore channels and disease. | Q54215446 |
| | SWISS-MODEL: homology modelling of protein structures and complexes. | Q55518681 |
| | Two-pore channels open up | Q59054754 |
| | A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca signaling in human cells | Q59353892 |
| | NAADP-dependent Ca signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system | Q59354303 |
| | Antipsychotic pimozide is a potent Ca2+ channel blocker in heart | Q68459661 |
| | Degeneration of an intracellular ion channel in the primate lineage by relaxation of selective constraints | Q84209506 |
| | Preparation and use of sea urchin egg homogenates for studying NAADP-mediated Ca²⁺ release | Q85241464 |
| | Phosphatidylinositol-3,5-bisphosphate lipid-binding-induced activation of the human two-pore channel 2 | Q88504875 |
| | MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca2+ and Mn2+ | Q90785236 |
| | An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals | Q28294394 |
| | Two-pore channels (TPCs): current controversies | Q28302766 |
| | Convergent regulation of the lysosomal two-pore channel-2 by Mg²⁺, NAADP, PI(3,5)P₂ and multiple protein kinases | Q28307378 |
| | Multiple cationic amphiphiles induce a Niemann-Pick C phenotype and inhibit Ebola virus entry and infection | Q28486226 |
| | The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores | Q28585336 |
| | Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection | Q28588877 |
| | A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity | Q30279239 |
| | GalaxyWEB server for protein structure prediction and refinement | Q30417400 |
| | Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs | Q30449316 |
| | α-SNAP regulates dynamic, on-site assembly and calcium selectivity of Orai1 channels. | Q30798747 |
| | Verapamil block of large-conductance Ca-activated K channels in rat aortic myocytes | Q32060905 |
| | Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-Lymphocytes | Q33596032 |
| | An enzymatic virus-like particle assay for sensitive detection of virus entry | Q33624624 |
| | Comprehensive analysis of ebola virus GP1 in viral entry | Q33724185 |
| | Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking | Q33816664 |
| | Naringenin Impairs Two-Pore Channel 2 Activity And Inhibits VEGF-Induced Angiogenesis. | Q33894915 |
| | Molecular mechanisms of selective estrogen receptor modulator (SERM) action. | Q33922673 |
| | A direct optimization approach to hidden Markov modeling for single channel kinetics | Q34174076 |
| | Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein | Q34408840 |
| | Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment | Q34464824 |
| | Function and dysfunction of two-pore channels | Q34483905 |
| | Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function. | Q34551759 |
| | The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation | Q34583526 |
| | Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs | Q35050840 |
| | Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels. | Q35082699 |
| | Inhibition of Ebola and Marburg Virus Entry by G Protein-Coupled Receptor Antagonists | Q35706815 |
| | Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling | Q36217193 |
| | Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology | Q36536361 |
| | Rapid estrogen actions on ion channels: A survey in search for mechanisms | Q37057980 |
| | NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist | Q37229250 |
| | Expression of Ebolavirus glycoprotein on the target cells enhances viral entry | Q37234907 |
| | Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease | Q37944859 |
| | Evolution of acidic Ca²⁺ stores and their resident Ca²⁺-permeable channels | Q38319655 |
| | Toremifene interacts with and destabilizes the Ebola virus glycoprotein | Q38760720 |
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Orthoebolavirus zairense | Q10538943 |
| P304 | page(s) | 1151-1161 | |
| P577 | publication date | 2018-11-05 | |
| P1433 | published in | BBA: Molecular Cell Research | Q15754442 |
| P1476 | title | Mining of Ebola virus entry inhibitors identifies approved drugs as two-pore channel pore blockers | |
| P478 | volume | 1866 | |