The Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex?

scientific article published on June 2012

The Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1166/MSR.2012.1003
P932PMC publication ID4193953
P698PubMed publication ID25309835
P5875ResearchGate publication ID266951003

P50authorSandip PatelQ37379421
P2093author name stringJonathan S Marchant
Timothy F Walseth
Yaping Lin-Moshier
P2860cites workLeucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADPQ24293723
Inwardly rectifying potassium channels: their structure, function, and physiological rolesQ24296441
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signalingQ24316454
NAADP mobilizes calcium from acidic organelles through two-pore channelsQ24318546
Two-pore channels form homo- and heterodimersQ24337485
Nicotinate-adenine dinucleotide phosphate-induced Ca(2+)-release does not behave as a Ca(2+)-induced Ca(2+)-release systemQ24534332
Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin eggQ24600390
Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cellsQ24600457
TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+Q24621022
Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channelsQ24633669
Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentinQ24656027
Pharmacological properties of the Ca2+-release mechanism sensitive to NAADP in the sea urchin eggQ24672945
Voltage-gated sodium channel-associated proteins and alternative mechanisms of inactivation and blockQ26991734
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cellsQ28138792
Spatial control of Ca2+ signaling by nicotinic acid adenine dinucleotide phosphate diffusion and gradientsQ28139670
Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channelsQ28141035
Sperm deliver a new second messenger: NAADPQ28204936
NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggsQ28216586
Voltage-gated potassium channels: regulation by accessory subunitsQ28239190
Primary sequence and immunological characterization of beta-subunit of high conductance Ca(2+)-activated K+ channel from smooth muscleQ28243668
Domain assembly of NAADP-gated two-pore channelsQ28250269
Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1Q28264441
Linking NAADP to ion channel activity: a unifying hypothesisQ28265293
An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organellesQ28265825
Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signalingQ28277133
Activation and inactivation of Ca2+ release by NAADP+Q28277642
Unique inactivation properties of NAADP-sensitive Ca2+ releaseQ28281723
Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomesQ28283147
Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activityQ28284283
An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signalsQ28294394
Nicotinic Acid Adenine Dinucleotide Phosphate Analogues Containing Substituted Nicotinic Acid: Effect of Modification on Ca2+ ReleaseQ42700042
NAADP binding to its target protein in sea urchin eggs requires phospholipidsQ42815147
NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptorsQ42917771
Nicotinic acid adenine dinucleotide phosphate (NAADP(+)) is an essential regulator of T-lymphocyte Ca(2+)-signalingQ42920018
Nicotinic acid-adenine dinucleotide phosphate activates the skeletal muscle ryanodine receptorQ43002260
Modulation of NAADP (nicotinic acid-adenine dinucleotide phosphate) receptors by K+ ions: evidence for multiple NAADP receptor conformationsQ43003228
Ca(2+) release induced by cADP-ribose is mediated by FKBP12.6 proteins in mouse bladder smooth muscleQ43069759
Prolonged inactivation of nicotinic acid adenine dinucleotide phosphate-induced Ca2+ release mediates a spatiotemporal Ca2+ memoryQ43515742
NAADP receptors are present and functional in the heartQ43670733
A putative two pore channel AtTPC1 mediates Ca(2+) flux in Arabidopsis leaf cellsQ43751036
Lack of effect of cADP-ribose and NAADP on the activity of skeletal muscle and heart ryanodine receptorsQ43757027
Role of FKBP12.6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscleQ43917329
Nicotinic acid adenine dinucleotide phosphate mediates Ca2+ signals and contraction in arterial smooth muscle via a two-pool mechanismQ44248159
Ryanodine receptor type I and nicotinic acid adenine dinucleotide phosphate receptors mediate Ca2+ release from insulin-containing vesicles in living pancreatic beta-cells (MIN6).Q44285317
Nicotinic acid adenine dinucleotide phosphate potentiates neurite outgrowthQ45140500
Calcium-Activated K+ Channels and Calcium-Induced Calcium Release by Slow Vacuolar Ion Channels in Guard Cell Vacuoles Implicated in the Control of Stomatal ClosureQ46244932
Role of cyclic ADP-ribose in Ca2+-induced Ca2+ release and vasoconstriction in small renal arteriesQ46646165
The vacuolar Ca2+-activated channel TPC1 regulates germination and stomatal movementQ48146660
Characterization of NAADP(+) binding in sea urchin eggsQ48562730
Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brainQ48629603
The fluorescence protease protection (FPP) assay to determine protein localization and membrane topology.Q50690888
NAADP mobilizes calcium from the endoplasmic reticular Ca(2+) store in T-lymphocytes.Q50698075
NAADP controls cross-talk between distinct Ca2+ stores in the heart.Q50700993
Planar patch clamp approach to characterize ionic currents from intact lysosomes.Q51552498
Triggering of Ca2+ signals by NAADP-gated two-pore channels: a role for membrane contact sites?Q51823379
Identification of the gene causing mucolipidosis type IV.Q52165526
Direct Photoaffinity Labeling of the Kir6.2 Subunit of the ATP-sensitive K+Channel by 8-Azido-ATPQ58449729
Inositol trisphosphate induces calcium release from nonmitochondrial stores i sea urchin egg homogenatesQ68945438
Nicotinate adenine dinucleotide phosphate (NAADP) triggers a specific calcium release system in sea urchin eggsQ72536435
Widespread distribution of binding sites for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate, in the brainQ73019132
Functional visualization of the separate but interacting calcium stores sensitive to NAADP and cyclic ADP-riboseQ73198872
Structural determinants of nicotinic acid adenine dinucleotide phosphate important for its calcium-mobilizing activityQ73575349
Identification of a calcium channel modulator using a high throughput yeast two-hybrid screenQ77463629
Generation of specific Ca(2+) signals from Ca(2+) stores and endocytosis by differential coupling to messengersQ79207730
NAADP as an intracellular messenger regulating lysosomal calcium-release channelsQ82669208
Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytesQ83056883
Acidic Ca(2+) stores come to the foreQ83879499
Degeneration of an intracellular ion channel in the primate lineage by relaxation of selective constraintsQ84209506
Pyridine nucleotide metabolites stimulate calcium release from sea urchin egg microsomes desensitized to inositol trisphosphateQ28299232
Cyclic ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomesQ28302379
KATP channels as molecular sensors of cellular metabolismQ28303315
Messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiationQ28305783
A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-riboseQ28306365
NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ storesQ28366121
The potassium channel subunit Kvbeta3 interacts with pannexin 1 and attenuates its sensitivity to changes in redox potentialsQ28510336
NAADP-induced Ca(2+ signaling in response to endothelin is via the receptor subtype B and requires the integrity of lipid rafts/caveolaeQ28572693
The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal storesQ28585336
TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscleQ28588920
Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptorQ28592962
The versatility and universality of calcium signallingQ29547402
Signals for sorting of transmembrane proteins to endosomes and lysosomesQ29547469
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currentsQ29615755
Reconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1(-/-) cellsQ30503399
Molecular properties of inositol 1,4,5-trisphosphate receptorsQ33666650
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal traffickingQ33816664
TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADPQ33840138
Inositol trisphosphate receptor Ca2+ release channels.Q33983069
Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signalsQ34065665
Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain.Q34093833
Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphateQ34264314
Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressureQ34333480
Coordination of Ca2+ signalling by NAADP.Q34336886
Overview of molecular relationships in the voltage-gated ion channel superfamily.Q34480285
A transport mechanism for NAADP in a rat basophilic cell lineQ34483087
Functional biology of the alpha(2)delta subunits of voltage-gated calcium channelsQ34614867
Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels.Q34684877
Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.Q34685254
Ryanodine receptor calcium release channelsQ34882627
Triazine dyes are agonists of the NAADP receptor.Q35047514
The endoplasmic reticulum: a multifunctional signaling organelleQ35051249
Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channelsQ35067713
Lipid transfer and signaling at organelle contact sites: the tip of the icebergQ35141334
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complexQ35561043
NAADP-induced Ca2+ release -- a new signalling pathway.Q35749148
Regulation of a proteinaceous elicitor-induced Ca2+ influx and production of phytoalexins by a putative voltage-gated cation channel, OsTPC1, in cultured rice cells.Q35879911
The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.Q35944812
Emerging role of cyclic ADP-ribose (cADPR) in smooth muscleQ36020152
Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signalingQ36217193
GABA(A) receptor diversity and pharmacologyQ36579576
ADP-ribosyl cyclase: an enzyme that cyclizes NAD+ into a calcium-mobilizing metaboliteQ36743019
Multiplicity of protein interactions and functions of the voltage-gated calcium channel beta-subunit.Q36880873
NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonistQ37229250
Investigating cADPR and NAADP in intact and broken cell preparationsQ37292810
Ryanodine receptor structure: progress and challengesQ37300766
Localization and socialization: experimental insights into the functional architecture of IP3 receptorsQ37605803
Intracellular Ca2+ storage in health and disease: a dynamic equilibrium.Q37699891
Associated proteins: The universal toolbox controlling ligand gated ion channel functionQ37719959
TPC1-SV channels gain shapeQ37860753
The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels.Q37870269
Cyclic ADP-ribose and NAADP: fraternal twin messengers for calcium signalingQ37904885
GluN3 subunit-containing NMDA receptors: not just one-trick poniesQ37975344
Solubilization of receptors for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphateQ38363072
Defining nicotinic agonist binding surfaces through photoaffinity labelingQ38779796
An N-terminal dileucine motif directs two-pore channels to the tonoplast of plant cellsQ39366914
Acidic NAADP-releasable Ca(2+) compartments in the megakaryoblastic cell line MEG01.Q39538658
NAADP links histamine H1 receptors to secretion of von Willebrand factor in human endothelial cellsQ39583631
Second messenger signaling: multiple receptors for NAADP.Q39825378
Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cellsQ40609889
NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cellsQ40672258
Time sensing by NAADP receptors.Q41819567
Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive poolQ41865560
Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytesQ41891896
Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhance the sensitivity of NAADP receptors for their ligandQ42254591
Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle: the role of FK506 binding proteins and mTOR.Q42681982
Analogues of the nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist Ned-19 indicate two binding sites on the NAADP receptorQ42693432
P433issue1
P304page(s)63-76
P577publication date2012-06-01
P1433published inMessenger (Los Angeles, Calif. : Print)Q27724829
P1476titleThe Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex?
P478volume1