scholarly article | Q13442814 |
P356 | DOI | 10.1002/BIES.201300118 |
P8608 | Fatcat ID | release_mmifxlxy3naspi4njm7t4yk7ha |
P698 | PubMed publication ID | 24277557 |
P50 | author | Antony Giuseppe Galione | Q24005240 |
P2093 | author name string | Anthony J Morgan | |
P2860 | cites work | Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP | Q24293723 |
mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state | Q24315101 | ||
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling | Q24316454 | ||
NAADP mobilizes calcium from acidic organelles through two-pore channels | Q24318546 | ||
Two-pore channels form homo- and heterodimers | Q24337485 | ||
Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg | Q24600390 | ||
Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells | Q24600457 | ||
TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+ | Q24621022 | ||
Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channels | Q24633669 | ||
Pharmacological properties of the Ca2+-release mechanism sensitive to NAADP in the sea urchin egg | Q24672945 | ||
Regulation of ion channels by pyridine nucleotides | Q26827261 | ||
Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels | Q28141035 | ||
NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs | Q28216586 | ||
Domain assembly of NAADP-gated two-pore channels | Q28250269 | ||
Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1 | Q28264441 | ||
Linking NAADP to ion channel activity: a unifying hypothesis | Q28265293 | ||
An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles | Q28265825 | ||
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes | Q28276964 | ||
Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomes | Q28283147 | ||
Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organelles | Q28286984 | ||
An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals | Q28294394 | ||
A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose | Q28306365 | ||
Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of rats | Q28569468 | ||
The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores | Q28585336 | ||
TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle | Q28588920 | ||
Inositol trisphosphate and calcium signalling mechanisms | Q29012316 | ||
PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome | Q29543488 | ||
Reconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1(-/-) cells | Q30503399 | ||
Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-Lymphocytes | Q33596032 | ||
Calcium signaling via two-pore channels: local or global, that is the question | Q33727697 | ||
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking | Q33816664 | ||
A novel ion channel formed by interaction of TRPML3 with TRPV5. | Q34612858 | ||
Mucolipin-3 regulates luminal calcium, acidification, and membrane fusion in the endosomal pathway | Q34684771 | ||
Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels. | Q34684877 | ||
Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation. | Q34685254 | ||
Two pore channel 2 differentially modulates neural differentiation of mouse embryonic stem cells | Q34776238 | ||
Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium | Q34866369 | ||
Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function | Q34959368 | ||
Regulation of TRP channels via lipid second messengers. | Q35057472 | ||
Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels | Q35067713 | ||
In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force | Q35839672 | ||
Sodium-activated potassium channels are functionally coupled to persistent sodium currents | Q35871140 | ||
Phosphoinositide isoforms determine compartment-specific ion channel activity | Q36094211 | ||
Identification of two-pore channel 2 as a novel regulator of osteoclastogenesis | Q36318794 | ||
Acid-sensitive TWIK and TASK two-pore domain potassium channels change ion selectivity and become permeable to sodium in extracellular acidification | Q36347770 | ||
Permeant calcium ion feed-through regulation of single inositol 1,4,5-trisphosphate receptor channel gating | Q36446417 | ||
Intracellular calcium release channels mediate their own countercurrent: the ryanodine receptor case study. | Q36908402 | ||
TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytes | Q37118266 | ||
Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH. | Q37817875 | ||
Sea urchin eggs in the acid reign | Q37830860 | ||
TPC1-SV channels gain shape | Q37860753 | ||
The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels. | Q37870269 | ||
Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease | Q37944859 | ||
Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilization | Q38028456 | ||
The CLC-5 2Cl(-)/H(+) exchange transporter in endosomal function and Dent's disease | Q38066187 | ||
TRIC channels supporting efficient Ca(2+) release from intracellular stores | Q38067578 | ||
Solubilization of receptors for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate | Q38363072 | ||
Questioning regulation of two-pore channels by NAADP | Q39515801 | ||
Acidic NAADP-releasable Ca(2+) compartments in the megakaryoblastic cell line MEG01. | Q39538658 | ||
NAADP links histamine H1 receptors to secretion of von Willebrand factor in human endothelial cells | Q39583631 | ||
TRPV1 shows dynamic ionic selectivity during agonist stimulation. | Q39994761 | ||
Composition of sea urchin egg homogenate determines its potency to inositol trisphosphate and cyclic ADPRibose-induced Ca2+ release | Q40195645 | ||
Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH. | Q41820235 | ||
Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes | Q41891896 | ||
NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing | Q42418448 | ||
Modulation of NAADP (nicotinic acid-adenine dinucleotide phosphate) receptors by K+ ions: evidence for multiple NAADP receptor conformations | Q43003228 | ||
Ca2+ release triggered by NAADP in hepatocyte microsomes | Q43258173 | ||
Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones | Q43591139 | ||
Lysosomal pathology and osteopetrosis upon loss of H+-driven lysosomal Cl- accumulation | Q44881936 | ||
The fou2 mutation in the major vacuolar cation channel TPC1 confers tolerance to inhibitory luminal calcium | Q46082785 | ||
Identification of voltage-dependent Ca2+ channels in sea urchin sperm | Q46820011 | ||
The vacuolar Ca2+-activated channel TPC1 regulates germination and stomatal movement | Q48146660 | ||
Insulin-mediated upregulation of T-type Ca2+ currents in GH3 cells is mediated by increased endosomal recycling and incorporation of surface membrane Cav3.1 channels | Q48449035 | ||
The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP. | Q50746326 | ||
Functional multimerization of mucolipin channel proteins. | Q51776446 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 173-83 | |
P577 | publication date | 2014-02-01 | |
P1433 | published in | BioEssays | Q4914614 |
P1476 | title | Two-pore channels (TPCs): current controversies | |
P478 | volume | 36 |
Q92857439 | A two-pore channel protein required for regulating mTORC1 activity on starvation |
Q41072178 | Activity-Dependent Exocytosis of Lysosomes Regulates the Structural Plasticity of Dendritic Spines. |
Q47657315 | Advances and current challenges in calcium signaling |
Q38226562 | An integrated mechanism of cardiomyocyte nuclear Ca(2+) signaling |
Q38846452 | Ca2+ release via two-pore channel type 2 (TPC2) is required for slow muscle cell myofibrillogenesis and myotomal patterning in intact zebrafish embryos. |
Q38620889 | Calcium signaling in membrane repair |
Q50197942 | Control of basal jasmonate signalling and defence through modulation of intracellular cation flux capacity |
Q41791017 | Departure gate of acidic Ca²⁺ confirmed |
Q33755055 | Drug-Loadable Calcium Alginate Hydrogel System for Use in Oral Bone Tissue Repair. |
Q61812437 | Endolysosomal Ca Signalling and Cancer Hallmarks: Two-Pore Channels on the Move, TRPML1 Lags Behind! |
Q28260464 | Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells |
Q38885377 | From contraction to gene expression: nanojunctions of the sarco/endoplasmic reticulum deliver site- and function-specific calcium signals |
Q28246421 | High susceptibility to fatty liver disease in two-pore channel 2-deficient mice |
Q40643402 | How does NAADP release lysosomal Ca2+? |
Q54958010 | In Vitro and In Vivo Osteogenic Activity of Titanium Implants Coated by Pulsed Laser Deposition with a Thin Film of Fluoridated Hydroxyapatite. |
Q34462083 | Lysosomal physiology |
Q93221684 | Membrane transport proteins in melanosomes: Regulation of ions for pigmentation |
Q58609396 | Mining of Ebola virus entry inhibitors identifies approved drugs as two-pore channel pore blockers |
Q38830313 | Modulation of Calcium Entry by the Endo-lysosomal System |
Q92641372 | NAADP Receptors |
Q47141627 | NAADP-evoked Ca2+ signals through two-pore channel-1 require arginine residues in the first S4-S5 linker |
Q34483914 | Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells. |
Q35691118 | Organellar channels and transporters |
Q34958437 | Organelle-specific subunit interactions of the vertebrate two-pore channel family |
Q58614179 | Plant Calcium Signaling in Response to Potassium Deficiency |
Q38844674 | Poring over two-pore channel pore mutants |
Q38872878 | Preferential Coupling of the NAADP Pathway to Exocytosis in T-Cells. |
Q28081340 | Regulation and roles of Ca2+ stores in human sperm |
Q42596069 | TPC1 Knockout Knocks Out TPC1. |
Q39271543 | TPC1 has two variant isoforms, and their removal has different effects on endo-lysosomal functions compared to loss of TPC2. |
Q36931154 | TPC2 controls pigmentation by regulating melanosome pH and size |
Q27306330 | TPC2 mediates new mechanisms of platelet dense granule membrane dynamics through regulation of Ca2+ release |
Q28262391 | TPC: the NAADP discovery channel? |
Q49458862 | The Integration of Electrical Signals Originating in the Root of Vascular Plants. |
Q34583526 | The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation |
Q50457154 | The phosphoinositide PI(3,5)P₂ mediates activation of mammalian but not plant TPC proteins: functional expression of endolysosomal channels in yeast and plant cells. |
Q58615503 | The protein interaction networks of mucolipins and two-pore channels |
Q40041330 | The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes. |
Q35872288 | Two-Pore Channel 2 activity is required for slow muscle cell-generated Ca(2+) signaling during myogenesis in intact zebrafish. |
Q34531617 | Two-Pore Channels: Lessons from Mutant Mouse Models |
Q43099248 | Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart |
Q37613806 | Two-pore channels (TPCs): Novel voltage-gated ion channels with pleiotropic functions |
Q28085768 | Two-pore channels at the intersection of endolysosomal membrane traffic |
Q27346606 | Two-pore channels function in calcium regulation in sea star oocytes and embryos |