Two-pore channels (TPCs): current controversies

scientific article

Two-pore channels (TPCs): current controversies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/BIES.201300118
P8608Fatcat IDrelease_mmifxlxy3naspi4njm7t4yk7ha
P698PubMed publication ID24277557

P50authorAntony Giuseppe GalioneQ24005240
P2093author name stringAnthony J Morgan
P2860cites workLeucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADPQ24293723
mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic stateQ24315101
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signalingQ24316454
NAADP mobilizes calcium from acidic organelles through two-pore channelsQ24318546
Two-pore channels form homo- and heterodimersQ24337485
Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin eggQ24600390
Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cellsQ24600457
TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+Q24621022
Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channelsQ24633669
Pharmacological properties of the Ca2+-release mechanism sensitive to NAADP in the sea urchin eggQ24672945
Regulation of ion channels by pyridine nucleotidesQ26827261
Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channelsQ28141035
NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggsQ28216586
Domain assembly of NAADP-gated two-pore channelsQ28250269
Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1Q28264441
Linking NAADP to ion channel activity: a unifying hypothesisQ28265293
An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organellesQ28265825
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomesQ28276964
Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomesQ28283147
Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organellesQ28286984
An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signalsQ28294394
A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-riboseQ28306365
Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of ratsQ28569468
The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal storesQ28585336
TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscleQ28588920
Inositol trisphosphate and calcium signalling mechanismsQ29012316
PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosomeQ29543488
Reconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1(-/-) cellsQ30503399
Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-LymphocytesQ33596032
Calcium signaling via two-pore channels: local or global, that is the questionQ33727697
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal traffickingQ33816664
A novel ion channel formed by interaction of TRPML3 with TRPV5.Q34612858
Mucolipin-3 regulates luminal calcium, acidification, and membrane fusion in the endosomal pathwayQ34684771
Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels.Q34684877
Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.Q34685254
Two pore channel 2 differentially modulates neural differentiation of mouse embryonic stem cellsQ34776238
Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calciumQ34866369
Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome functionQ34959368
Regulation of TRP channels via lipid second messengers.Q35057472
Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channelsQ35067713
In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive forceQ35839672
Sodium-activated potassium channels are functionally coupled to persistent sodium currentsQ35871140
Phosphoinositide isoforms determine compartment-specific ion channel activityQ36094211
Identification of two-pore channel 2 as a novel regulator of osteoclastogenesisQ36318794
Acid-sensitive TWIK and TASK two-pore domain potassium channels change ion selectivity and become permeable to sodium in extracellular acidificationQ36347770
Permeant calcium ion feed-through regulation of single inositol 1,4,5-trisphosphate receptor channel gatingQ36446417
Intracellular calcium release channels mediate their own countercurrent: the ryanodine receptor case study.Q36908402
TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytesQ37118266
Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH.Q37817875
Sea urchin eggs in the acid reignQ37830860
TPC1-SV channels gain shapeQ37860753
The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels.Q37870269
Molecular mechanisms of endolysosomal Ca2+ signalling in health and diseaseQ37944859
Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilizationQ38028456
The CLC-5 2Cl(-)/H(+) exchange transporter in endosomal function and Dent's diseaseQ38066187
TRIC channels supporting efficient Ca(2+) release from intracellular storesQ38067578
Solubilization of receptors for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphateQ38363072
Questioning regulation of two-pore channels by NAADPQ39515801
Acidic NAADP-releasable Ca(2+) compartments in the megakaryoblastic cell line MEG01.Q39538658
NAADP links histamine H1 receptors to secretion of von Willebrand factor in human endothelial cellsQ39583631
TRPV1 shows dynamic ionic selectivity during agonist stimulation.Q39994761
Composition of sea urchin egg homogenate determines its potency to inositol trisphosphate and cyclic ADPRibose-induced Ca2+ releaseQ40195645
Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH.Q41820235
Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytesQ41891896
NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killingQ42418448
Modulation of NAADP (nicotinic acid-adenine dinucleotide phosphate) receptors by K+ ions: evidence for multiple NAADP receptor conformationsQ43003228
Ca2+ release triggered by NAADP in hepatocyte microsomesQ43258173
Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neuronesQ43591139
Lysosomal pathology and osteopetrosis upon loss of H+-driven lysosomal Cl- accumulationQ44881936
The fou2 mutation in the major vacuolar cation channel TPC1 confers tolerance to inhibitory luminal calciumQ46082785
Identification of voltage-dependent Ca2+ channels in sea urchin spermQ46820011
The vacuolar Ca2+-activated channel TPC1 regulates germination and stomatal movementQ48146660
Insulin-mediated upregulation of T-type Ca2+ currents in GH3 cells is mediated by increased endosomal recycling and incorporation of surface membrane Cav3.1 channelsQ48449035
The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP.Q50746326
Functional multimerization of mucolipin channel proteins.Q51776446
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)173-83
P577publication date2014-02-01
P1433published inBioEssaysQ4914614
P1476titleTwo-pore channels (TPCs): current controversies
P478volume36

Reverse relations

cites work (P2860)
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