Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals

scientific article published on 29 October 2012

Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/JCS.118836
P932PMC publication ID4208295
P698PubMed publication ID23108667
P5875ResearchGate publication ID232738500

P50authorEmily R. EdenQ37372685
Clare E FutterQ37372706
Sandip PatelQ37379421
Anthony H V SchapiraQ66915960
P2093author name stringBethan S Kilpatrick
P2860cites workNAADP as an intracellular messenger regulating lysosomal calcium-release channelsQ82669208
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Essential requirement for two-pore channel 1 in NAADP-mediated calcium signalingQ24316454
NAADP mobilizes calcium from acidic organelles through two-pore channelsQ24318546
Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cellsQ24600457
Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomesQ24672025
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cellsQ28138792
NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggsQ28216586
Linking NAADP to ion channel activity: a unifying hypothesisQ28265293
Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signalingQ28277133
An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signalsQ28294394
Messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiationQ28305783
NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ storesQ28366121
The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal storesQ28585336
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Structural interaction between RYRs and DHPRs in calcium release units of cardiac and skeletal muscle cellsQ34542127
Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calciumQ34866369
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Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channelsQ35067713
Lipid transfer and signaling at organelle contact sites: the tip of the icebergQ35141334
Flirting in little space: the ER/mitochondria Ca2+ liaisonQ35628367
Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells.Q36085273
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The role of calcium and other ions in sorting and delivery in the late endocytic pathwayQ36979614
Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptorsQ37227943
NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonistQ37229250
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioningQ37267618
Ryanodine receptor structure: progress and challengesQ37300766
Ca(2+) signalling in the Golgi apparatus.Q37840603
Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cellsQ40609889
Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium releaseQ41822869
NAADP: a universal Ca2+ triggerQ42444377
Intralysosomal hydrolysis of glycyl-L-phenylalanine 2-naphthylamideQ42560391
NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptorsQ42917771
The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organellesQ42919564
The Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex?Q42940716
Nicotinic acid-adenine dinucleotide phosphate activates the skeletal muscle ryanodine receptorQ43002260
Membrane contacts between endosomes and ER provide sites for PTP1B-epidermal growth factor receptor interactionQ43179203
Lysosome-sarcoplasmic reticulum junctions. A trigger zone for calcium signaling by nicotinic acid adenine dinucleotide phosphate and endothelin-1.Q45032464
A new method of preparing gold probes for multiple-labeling cytochemistryQ49320313
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P433issuePt 1
P407language of work or nameEnglishQ1860
P304page(s)60-66
P577publication date2012-10-29
P1433published inJournal of Cell ScienceQ1524177
P1476titleDirect mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals
P478volume126