Homer and the ryanodine receptor

scientific article published on 10 June 2009

Homer and the ryanodine receptor is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S00249-009-0494-1
P698PubMed publication ID19513708

P2093author name stringPierre Pouliquin
Angela Fay Dulhunty
P2860cites workSignaling proteins in raft-like microdomains are essential for Ca2+ wave propagation in glial cells.Q52572812
Functional interaction of neuronal Cav1.3 L-type calcium channel with ryanodine receptor type 2 in the rat hippocampus.Q53529693
Excitation-contraction coupling in airway smooth muscle.Q53606883
Modulation of Ca2+ release channel activity from sarcoplasmic reticulum by annexin VI (67-kDa calcimedin)Q68475626
Mouse brain and muscle tissues constitutively express high levels of Homer proteinsQ73395510
Evidence for a role of C-terminal amino acid residues in skeletal muscle Ca2+ release channel (ryanodine receptor) functionQ73588363
Endothelin-1 activates Homer 1alpha expression via mitogen-activated protein kinase in cardiac myocytesQ79756228
Transition of Homer isoforms during skeletal muscle regenerationQ94461709
The Homer family proteinsQ21184127
Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptorsQ22007971
Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteinsQ22008754
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing heartsQ22254160
Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 ReceptorsQ24295021
Functional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2AQ24310208
Structural organization of the endoplasmic reticulumQ24538821
Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognitionQ27622377
The N-terminal domain of Homer/Vesl is a new class II EVH1 domainQ27633888
NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer ProteinsQ27649708
The Shank family of scaffold proteinsQ28144084
Assembly of Cell Regulatory Systems Through Protein Interaction DomainsQ28155799
Differential functional interaction of two Vesl/Homer protein isoforms with ryanodine receptor type 1: a novel mechanism for control of intracellular calcium signalingQ28179595
Vesl/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signalingQ28190523
Homer regulates gain of ryanodine receptor type 1 channel complexQ28201200
ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological diseaseQ28204585
Homer: a protein that selectively binds metabotropic glutamate receptorsQ28305877
Molecular interaction of dihydropyridine receptors with type-1 ryanodine receptors in rat brainQ28359643
Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscleQ28507420
Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscleQ28508989
The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytesQ28510065
Phosphorylation of Homer3 by calcium/calmodulin-dependent kinase II regulates a coupling state of its target molecules in Purkinje cellsQ28512787
Cain, a novel physiologic protein inhibitor of calcineurinQ28570296
An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cellsQ28584758
Homer proteins regulate sensitivity to cocaineQ28587355
Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activityQ28593398
TRP channelsQ29616673
Type 3 ryanodine receptors of skeletal muscle are segregated in a parajunctional positionQ30803286
Subcellular distribution of Homer 1b/c in relation to endoplasmic reticulum and plasma membrane proteins in Purkinje neuronsQ30955093
TRPC3-interacting triadic proteins in skeletal muscleQ33316168
Modulation of ion channels: a "current" view of AKAPsQ33703246
Identification of a ryanodine receptor in rat heart mitochondriaQ33942032
The beta 1a subunit is essential for the assembly of dihydropyridine-receptor arrays in skeletal muscleQ34144818
Ca(2+)-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca(2+) release channel in skeletal muscle.Q34179106
Intracellular Ca(2+) pools in neuronal signallingQ34278043
Homer as both a scaffold and transduction molecule.Q34693516
Nuclear Ca2+ regulates cardiomyocyte function.Q34737223
Contributions of protein kinase A anchoring proteins to compartmentation of cAMP signaling in the heartQ34751180
Interactions between dihydropyridine receptors and ryanodine receptors in striated muscleQ34843211
Ryanodine receptor calcium release channelsQ34882627
The endoplasmic reticulum and neuronal calcium signalling.Q35051292
Calcineurin and intracellular Ca2+-release channels: regulation or association?Q35586591
A ryanodine receptor-like molecule expressed in the osteoclast plasma membrane functions in extracellular Ca2+ sensing.Q35763440
Three-dimensional distribution of cardiac Na+-Ca2+ exchanger and ryanodine receptor during developmentQ35972980
Ca2+ entry-independent effects of L-type Ca2+ channel modulators on Ca2+ sparks in ventricular myocytes.Q36168982
Effects of Vesl/Homer proteins on intracellular signalingQ36239074
Role of ryanodine receptors in the assembly of calcium release units in skeletal muscleQ36276654
Dense core secretory vesicles revealed as a dynamic Ca(2+) store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera.Q36293994
Interplay between intra- and extracellular calcium ions.Q36526749
Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1Q36529038
Regulation of NFAT activation: a potential therapeutic target for immunosuppression.Q36585011
Signaling for vesicle mobilization and synaptic plasticityQ36681356
The mAKAP signalosome and cardiac myocyte hypertrophy.Q36814938
Modulation of the ryanodine receptor and intracellular calciumQ36824050
Multiple activation mechanisms of store-operated TRPC channels in smooth muscle cellsQ36872135
Homer proteins in Ca2+ signaling by excitable and non-excitable cellsQ36873568
Presynaptic ryanodine receptor-CamKII signaling is required for activity-dependent capture of transiting vesiclesQ37029136
The sarcoplasmic reticulum: an organized patchwork of specialized domains.Q37081743
Auxiliary Ca(2+) channel subunits: lessons learned from muscle.Q37105617
NFAT activation by membrane potential follows a calcium pathway distinct from other activity-related transcription factors in skeletal muscle cellsQ40026864
Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteinsQ40315222
Expression of the ryanodine receptor isoforms in immune cellsQ40773094
Gating of store-operated channels by conformational coupling to ryanodine receptorsQ40855582
Calcium/calmodulin-dependent protein kinase IIdelta associates with the ryanodine receptor complex and regulates channel function in rabbit heart.Q41841555
Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibersQ41882302
Functional properties of ryanodine receptors carrying three amino acid substitutions identified in patients affected by multi-minicore disease and central core disease, expressed in immortalized lymphocytesQ41996021
The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.Q42054647
Ca2+ signaling in microdomains: Homer1 mediates the interaction between RyR2 and Cav1.2 to regulate excitation-contraction couplingQ42170028
Alternative splicing of ryanodine receptors modulates cardiomyocyte Ca2+ signaling and susceptibility to apoptosisQ42508822
Oligomerization of the cardiac ryanodine receptor C-terminal tailQ42747862
HOMER2 binds MYO18B and enhances its activity to suppress anchorage independent growthQ42829829
NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptorsQ42917771
Protein-protein interactions in intracellular Ca2+-release channel function.Q42992623
A ryanodine fluorescent derivative reveals the presence of high-affinity ryanodine binding sites in the Golgi complex of rat sympathetic neurons, with possible functional roles in intracellular Ca(2+) signaling.Q43615270
Rapid redistribution of the postsynaptic density protein PSD-Zip45 (Homer 1c) and its differential regulation by NMDA receptors and calcium channels.Q43819953
The transmembrane segment of ryanodine receptor contains an intracellular membrane retention signal for Ca(2+) release channelQ43847025
Dysfunction of store-operated calcium channel in muscle cells lacking mg29.Q43978759
Homer proteins and InsP(3) receptors co-localise in the longitudinal sarcoplasmic reticulum of skeletal muscle fibres.Q44178819
Store operated Ca2+ influx by selective depletion of ryanodine sensitive Ca2+ pools in primary human skeletal muscle cellsQ44400229
Depolarization-induced Ca2+ release in ischemic spinal cord white matter involves L-type Ca2+ channel activation of ryanodine receptorsQ44607273
Homer protein increases activation of Ca2+ sparks in permeabilized skeletal muscleQ44683442
Activity-inducible protein Homer1a/Vesl-1S promotes redistribution of postsynaptic protein Homer1c/Vesl-1L in cultured rat hippocampal neuronsQ44708409
Differential expression of Homer family proteins in the developing mouse brainQ44873450
Activity-dependent liberation of synaptic neuropeptide vesicles.Q45219239
In vitro modulation of the cardiac ryanodine receptor activity by Homer1.Q46083921
Functional ryanodine receptor expression is required for NAADP-mediated local Ca2+ signaling in T-lymphocytes.Q46387081
The foot structure from the type 1 ryanodine receptor is required for functional coupling to store-operated channelsQ46477078
Ryanodine receptor arrays: not just a pretty pattern?Q46711012
Homer modulates NFAT-dependent signaling during muscle differentiationQ46754105
Mutation of Drosophila homer disrupts control of locomotor activity and behavioral plasticity.Q46919558
Isolation of PSD-Zip45, a novel Homer/vesl family protein containing leucine zipper motifs, from rat brainQ48006881
vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long-term potentiation and synaptogenesisQ48047127
DNA methylation regulates tissue-specific expression of Shank3.Q48210930
Dihydropyridine receptors and type 1 ryanodine receptors constitute the molecular machinery for voltage-induced Ca2+ release in nerve terminals.Q48467694
Targeting and retention of type 1 ryanodine receptors to the endoplasmic reticulumQ48543907
Functional coupling between ryanodine receptors and L-type calcium channels in neuronsQ48940555
Effects of an alpha-helical ryanodine receptor C-terminal tail peptide on ryanodine receptor activity: modulation by Homer.Q52571077
P433issue1
P304page(s)91-102
P577publication date2009-06-10
P1433published inEuropean Biophysics JournalQ5412316
P1476titleHomer and the ryanodine receptor
P478volume39

Reverse relations

cites work (P2860)
Q34052215Calcium channels in the development, maturation, and function of spermatozoa
Q38024032Calcium-dependent networks in dopamine-glutamate interaction: the role of postsynaptic scaffolding proteins.
Q37007962Conformation of ryanodine receptor-2 gates store-operated calcium entry in rat pulmonary arterial myocytes
Q34720138Down-regulation of Homer1b/c expression protects cultured neurons after traumatic injury
Q57817418Drebrin Isoforms Critically Regulate NMDAR- and mGluR-Dependent LTD Induction
Q39016129Evolving approaches to heart regeneration by therapeutic stimulation of resident cardiomyocyte cell cycle.
Q34989683Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA.
Q34504097Functional screening identifies miRNAs inducing cardiac regeneration.
Q38126463Homer protein family regulation in skeletal muscle and neuromuscular adaptation
Q38095898Homer proteins in Ca²⁺ entry.
Q47866769Homer, Spikar, and Other Drebrin-Binding Proteins in the Brain.
Q59790186Polymorphisms of HOMER1 gene are associated with piglet splay leg syndrome and one significant SNP can affect its intronic promoter activity in vitro
Q92589002Skeletal muscle: A review of molecular structure and function, in health and disease
Q47419234The structural basis of ryanodine receptor ion channel function
Q34969926Three 4-letter words of hypertension-related cardiac hypertrophy: TRPC, mTOR, and HDAC.

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