Multiple roles of chemokine CXCL12 in the central nervous system: a migration from immunology to neurobiology

scientific article published on 26 November 2007

Multiple roles of chemokine CXCL12 in the central nervous system: a migration from immunology to neurobiology is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.PNEUROBIO.2007.11.003
P932PMC publication ID2324067
P698PubMed publication ID18177992
P5875ResearchGate publication ID5672305

P50authorRichard M RansohoffQ87833085
P2093author name stringMeizhang Li
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Assembly of trigeminal sensory ganglia by chemokine signaling.Q47073243
Stromal cell-derived factor-1 antagonizes slit/robo signaling in vivo.Q47073437
Towing of sensory axons by their migrating target cells in vivoQ47073616
Chemokine signaling mediates self-organizing tissue migration in the zebrafish lateral lineQ47073869
Guidance of primordial germ cell migration by the chemokine SDF-1.Q47073968
Signaling pathways controlling primordial germ cell migration in zebrafishQ47073985
Chemokine signaling regulates sensory cell migration in zebrafishQ47074210
GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo.Q47286150
CXCL12 in malignant glial tumors: a possible role in angiogenesis and cross-talk between endothelial and tumoral cells.Q47425824
Expression of stromal cell-derived factor-1 and CXCR4 chemokine receptor mRNAs in cultured rat glial and neuronal cellsQ47772243
Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development.Q47970889
Expression of chemokine receptors CXCR4, CCR2, CCR5 and CX3CR1 in neural progenitor cells isolated from the subventricular zone of the adult rat brainQ48090460
The role of the rhombic lip in avian cerebellum developmentQ48105702
Expression of chemokine receptors in the rat brainQ48156030
A time course study of the alterations in the development of the hamster cerebellar cortex after destruction of the overlying meningeal cells with 6-hydroxydopamine on the day of birthQ48178784
Molecular interaction between projection neuron precursors and invading interneurons via stromal-derived factor 1 (CXCL12)/CXCR4 signaling in the cortical subventricular zone/intermediate zone.Q48331522
CXCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cellsQ48354586
CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitisQ48365016
Involvement of distinct pioneer neurons in the formation of layer-specific connections in the hippocampus.Q48454466
A role for CXCL12 (SDF-1alpha) in the pathogenesis of multiple sclerosis: regulation of CXCL12 expression in astrocytes by soluble myelin basic proteinQ48494019
Embryonic development of the rat cerebellum. II. Translocation and regional distribution of the deep neuronsQ48557623
Expression of functional chemokine receptors by rat cerebellar neuronsQ48628802
Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitmentQ48701331
Persistent production of neurons from adult brain stem cells during recovery after stroke.Q48739755
Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesisQ48751052
Evidence that the HIV-1 coat protein gp120 causes neuronal apoptosis in the neocortex of rat via a mechanism involving CXCR4 chemokine receptorQ48752903
CXCL12 expression is predictive of a shorter time to tumor progression in low-grade glioma: a single-institution study in 50 patients.Q48795538
Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemiaQ48852632
Subtype-specific expression and genetic alterations of the chemokinereceptor gene CXCR4 in medulloblastomas.Q48895527
Radiosensitivity of the granule cell line and other cell types of the immature rat cerebellar cortexQ48926297
Developmental pattern of expression of the alpha chemokine stromal cell-derived factor 1 in the rat central nervous systemQ48943210
A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursorsQ48983632
TNF-alpha down-regulates CXCR4 expression in primary murine astrocytesQ49106823
Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementiaQ49156145
SDF-1alpha-mediated modulation of synaptic transmission in rat cerebellum.Q51385140
Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4+ T cell accumulation in rheumatoid arthritis synovium.Q52023146
Disruption of neuronal migration and radial glia in the developing cerebral cortex following ablation of Cajal-Retzius cells.Q52539654
Up-regulation of functional CXCR4 expression on human lymphocytes in sepsis.Q53590642
Viral load in HIV-associated dementiaQ58370987
Pulmonary Stromal-Derived Factor-1 Expression and Effect on Neutrophil Recruitment during Acute Lung InjuryQ59944200
Glutamate-like Immunoreactivity and Fate of Cajal-Retzius Cells in the Murine Cortex as Identified with Calretinin AntibodyQ61948268
Evaluation of the AIDS dementia complex in clinical trialsQ68589037
Cajal-Retzius cell ontogenesis and death in mouse brain visualized with horseradish peroxidase and electron microscopyQ68593926
Cajal-Retzius neurons in human cerebral cortex at midgestation show immunoreactivity for neurofilament and calcium-binding proteinsQ70890321
Differential coupling of CC chemokine receptors to multiple heterotrimeric G proteins in human interleukin-2-activated natural killer cellsQ71099766
P433issue2
P921main subjectimmunologyQ101929
nervous systemQ9404
P304page(s)116-131
P577publication date2007-11-26
P1433published inProgress in NeurobiologyQ15716615
P1476titleMultiple roles of chemokine CXCL12 in the central nervous system: a migration from immunology to neurobiology
P478volume84

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Q54486634Grk2 is an essential regulator of CXCR7 signalling in astrocytes.
Q42173784Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization
Q40449601High-level C-X-C chemokine receptor type 4 expression correlates with brain-specific metastasis following complete resection of non-small cell lung cancer
Q82288689High‐Level CXCR4 Expression Correlates with Brain‐Specific Metastasis of Non‐Small Cell Lung Cancer
Q38942670Homing of allogeneic nestin-positive hair follicle-associated pluripotent stem cells after maternal transplantation in experimental model of cortical dysplasia.
Q36535867Human cytomegalovirus infection inhibits CXCL12- mediated migration and invasion of human extravillous cytotrophoblasts
Q89597840Hypoxic-inflammatory responses under acute hypoxia: In Vitro experiments and prospective observational expedition trial
Q42415420Identification of a sustained neurogenic zone at the dorsal surface of the adult mouse hippocampus and its regulation by the chemokine SDF-1
Q24641998Imaging correlates of leukocyte accumulation and CXCR4/CXCL12 in multiple sclerosis
Q35876821Induction of Interleukin-1β by Human Immunodeficiency Virus-1 Viral Proteins Leads to Increased Levels of Neuronal Ferritin Heavy Chain, Synaptic Injury, and Deficits in Flexible Attention.
Q34044654Inhibition of hyaluronan synthesis protects against central nervous system (CNS) autoimmunity and increases CXCL12 expression in the inflamed CNS.
Q60912827Inhibition of stromal cell-derived factor-1α/CXCR4 signaling restores the blood-retina barrier in pericyte-deficient mouse retinas
Q36645434Intracerebroventricular Transplantation of Cord Blood-Derived Neural Progenitors in a Child With Severe Global Brain Ischemic Injury
Q37274612Intranasal Oncolytic Virotherapy with CXCR4-Enhanced Stem Cells Extends Survival in Mouse Model of Glioma
Q35005863JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals
Q58125170Loss of CXCR4/CXCL12 Signaling Causes Oculomotor Nerve Misrouting and Development of Motor Trigeminal to Oculomotor Synkinesis
Q34032023Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12.
Q35694119Matrix metalloproteinase-9 and stromal cell-derived factor-1 act synergistically to support migration of blood-borne monocytes into the injured spinal cord
Q30435441Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis
Q47074225Mmp25β facilitates elongation of sensory neurons during zebrafish development
Q37132290Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration.
Q24314285Monocyte migration and LFA-1-mediated attachment to brain microvascular endothelia is regulated by SDF-1 alpha through Lyn kinase
Q35154529Monocytes mediate HIV neuropathogenesis: mechanisms that contribute to HIV associated neurocognitive disorders
Q49343068Multisystem multitasking by CXCL12 and its receptors CXCR4 and ACKR3.
Q30441058Murine adult neural progenitor cells alter their proliferative behavior and gene expression after the activation of Toll-like-receptor 3
Q37896669Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system.
Q30569766Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction.
Q44121137Nitric oxide inhibits CXCL12 expression in neuroinflammation
Q48401549Nuclear factor κB activation impairs ependymal ciliogenesis and links neuroinflammation to hydrocephalus formation.
Q42670400Opiate-induced hypernociception and chemokine receptors
Q30987183PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER.
Q57278871Para-inflammation-mediated retinal recruitment of bone marrow-derived myeloid cells following whole-body irradiation is CCL2 dependent
Q42044173Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration
Q30416178Plasma CXCL12 levels as a predictor of future stroke
Q36446374Post-CNS-inflammation expression of CXCL12 promotes the endogenous myelin/neuronal repair capacity following spontaneous recovery from multiple sclerosis-like disease
Q27335140Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina
Q36249136Prenatal exposure to ethanol stimulates hypothalamic CCR2 chemokine receptor system: Possible relation to increased density of orexigenic peptide neurons and ethanol drinking in adolescent offspring
Q35170354Prenatal stress is a vulnerability factor for altered morphology and biological activity of microglia cells
Q30412966Pro-cognitive properties of T cells
Q28388136Prophylactic Chronic Zinc Administration Increases Neuroinflammation in a Hypoxia-Ischemia Model
Q35633357Prospective Study of (68)Ga-NOTA-NFB: Radiation Dosimetry in Healthy Volunteers and First Application in Glioma Patients
Q45629246Protein profiling identified key chemokines that regulate the maintenance of human pluripotent stem cells
Q37149240Regulation of neuronal ferritin heavy chain, a new player in opiate-induced chemokine dysfunction
Q90263523Role of the Immune System in the Development of the Central Nervous System
Q48769706SDF-1 overexpression by mesenchymal stem cells enhances GAP-43-positive axonal growth following spinal cord injury
Q34633031SDF1 in the dorsal corticospinal tract promotes CXCR4+ cell migration after spinal cord injury
Q36310818SDF1-CXCR4 signaling contributes to persistent pain and hypersensitivity via regulating excitability of primary nociceptive neurons: involvement of ERK-dependent Nav1.8 up-regulation
Q35001235Secreted herpes simplex virus-2 glycoprotein G modifies NGF-TrkA signaling to attract free nerve endings to the site of infection.
Q39022668Serum CXCL12 Levels as a Novel Predictor of Future Stroke Recurrence in Patients with Acute Ischemic Stroke
Q48115341Serum CXCL12 levels are associated with stroke severity and lesion volumes in stroke patients
Q37462031Spatiotemporal expression and functional implication of CXCL14 in the developing mice cerebellum.
Q45419744Stromal cell-derived factor-1 and hepatocyte growth factor guide axon projections to the extraocular muscles.
Q42230502Stromal derived growth factor-1 (CXCL12) modulates synaptic transmission to immature neurons during post-ischemic cerebral repair
Q50491825Survival and Proliferation of Neural Progenitor-Derived Glioblastomas Under Hypoxic Stress is Controlled by a CXCL12/CXCR4 Autocrine-Positive Feedback Mechanism.
Q42131899THE MAGNIFICENT SEVENTH.
Q91955783Targeting G protein-coupled receptor for pain management
Q37643901The Autophagy Machinery: A New Player in Chemotactic Cell Migration
Q34560340The CXCL12/CXCR4/CXCR7 ligand-receptor system regulates neuro-glio-vascular interactions and vessel growth during human brain development.
Q64892118The Role of Chemokines in the Pathophysiology of Major Depressive Disorder.
Q90050404The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases
Q48201727The SDF-1 3'A genetic variation is correlated with elevated intra-tumor tissue and circulating concentration of CXCL12 in glial tumors: a study on Iranian anaplastic astrocytoma and glioblastoma multiforme patients.
Q82719617The SDF-1 3'a genetic variation of the chemokine SDF-1α (CXCL12) in parallel with its increased circulating levels is associated with susceptibility to MS: a study on Iranian multiple sclerosis patients
Q34473067The antiquity of chordate odorant receptors is revealed by the discovery of orthologs in the cnidarian Nematostella vectensis
Q37778548The blood–brain barrier, chemokines and multiple sclerosis
Q30460340The chemokine BRAK/CXCL14 regulates synaptic transmission in the adult mouse dentate gyrus stem cell niche
Q33611768The chemokine CXCL13 is a key regulator of B cell recruitment to the cerebrospinal fluid in acute Lyme neuroborreliosis.
Q85645722The diagnostic and prognostic value of serum CXCL12 levels in patients with ischemic stroke
Q37659898The evolution of chemotaxis assays from static models to physiologically relevant platforms
Q38167634The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets
Q55462721The presumed atypical chemokine receptor CXCR7 signals through G(i/o) proteins in primary rodent astrocytes and human glioma cells.
Q37692608The role of CXCR4 signaling in the migration of transplanted oligodendrocyte progenitors into the cerebral white matter.
Q38560936Thyroid Hormone Potentially Benefits Multiple Sclerosis via Facilitating Remyelination.
Q88041748Tissue remodeling in periplaque regions of multiple sclerosis spinal cord lesions
Q38502206Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor fasudil reveals cytoskeletal and pro-survival responses
Q52632026Upregulation of CXCR4 through promoter demethylation contributes to inflammatory hyperalgesia in rats.
Q89121242Widespread Effects of Chemokine 3' Untranslated Regions on mRNA Degradation and Protein Production in Human Cells
Q37768036Wiring Olfaction: The Cellular and Molecular Mechanisms that Guide the Development of Synaptic Connections from the Nose to the Cortex.
Q53022125[Tumor Cells and Micro-environment in Brain Metastases].
Q54242794cxcl12 gene engineered endothelial progenitor cells further improve the functions of oligodendrocyte precursor cells.
Q47828526miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis.

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