Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms

scientific article published on 27 November 2012

Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/MOL.112.082271
P932PMC publication ID3558807
P698PubMed publication ID23188715
P5875ResearchGate publication ID233789424

P50authorVeit FlockerziQ56384346
Marc FreichelQ90178430
Lutz BirnbaumerQ92613192
P2093author name stringHong Wu
Joel Abramowitz
Fang Zheng
Sung W Rhee
Kevin D Phelan
Matthew D Howell
Paul E Gottschall
U Thaung Shwe
P2860cites workCorticolimbic expression of TRPC4 and TRPC5 channels in the rodent brainQ21092250
Subunit composition of mammalian transient receptor potential channels in living cellsQ24530559
Essential role for TRPC5 in amygdala function and fear-related behavior.Q24657938
Genome-wide atlas of gene expression in the adult mouse brainQ26253934
Group I metabotropic glutamate receptors activate a calcium-sensitive transient receptor potential-like conductance in rat hippocampusQ28565008
Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1Q28582069
TRPC Channels Mediate a Muscarinic Receptor-Induced Afterdepolarization in Cerebral CortexQ30437078
A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learningQ30488913
Mechanisms of neuronal synchronization during epileptiform activityQ33748501
Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functionsQ33847729
Prolonged seizures and cellular injury: understanding the connectionQ33991332
NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cellsQ34249319
Excitatory amino acids as a final common pathway for neurologic disorders.Q34321926
Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neuronsQ34394699
Glutamate neurotoxicity and diseases of the nervous systemQ34560997
Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegenerationQ35776768
Contributions of T-type calcium channel isoforms to neuronal firingQ37817635
Cellular mechanisms of epilepsy: a status reportQ39510156
The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channelsQ39686696
Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4.Q40376711
TRPC1 and TRPC5 form a novel cation channel in mammalian brain.Q40812989
TRPC channels underlie cholinergic plateau potentials and persistent activity in entorhinal cortexQ43577780
Mouse gene knockout and knockin strategies in application to alpha subunits of Gi/Go family of G proteinsQ43842085
Trans-ACPD (trans-D,L-1-amino-1,3-cyclopentanedicarboxylic acid) elicited oscillation of membrane potentials in rat dorsolateral septal nucleus neurons recorded intracellularly in vitroQ44103655
Metabotropic glutamate receptor agonists potentiate a slow afterdepolarization in CNS neuronsQ44285007
Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model.Q44487940
Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damageQ45181343
Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior.Q45194025
Behavioral and convulsant effects of the (S) enantiomer of the group I metabotropic glutamate receptor agonist 3,5-DHPG in miceQ46436802
Ionic basis of spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells.Q47917540
Group I metabotropic glutamate receptor-dependent TRPC channel trafficking in hippocampal neurons.Q48220594
Characterization of a calcium-dependent current generating a slow afterdepolarization of CA3 pyramidal cells in rat hippocampal slice culturesQ48278673
An increase in persistent sodium current contributes to intrinsic neuronal bursting after status epilepticusQ48316462
Two-day radial-arm water maze learning and memory task; robust resolution of amyloid-related memory deficits in transgenic miceQ48401972
Differential distribution of TRP Ca2+ channel isoforms in mouse brainQ48505517
Activation of a metabotropic excitatory amino acid receptor potentiates spike-driven calcium increases in neurons of the dorsolateral septum.Q48912080
Electrophysiology of hippocampal neurons. II. After-potentials and repetitive firing.Q51302393
Plasma membrane insertion of TRPC5 channels contributes to the cholinergic plateau potential in hippocampal CA1 pyramidal neurons.Q54648032
Afterpotential generation in hippocampal pyramidal cellsQ72883749
1S, 3R-ACPD induces a region of negative slope conductance in the steady-state current-voltage relationship of hippocampal pyramidal cellsQ73271965
A comparison of the genes coding for canonical TRP channels and their M, V and P relativesQ73435189
P433issue2
P921main subjectexcitotoxicityQ901117
seizureQ6279182
P304page(s)429-438
P577publication date2012-11-27
P1433published inMolecular PharmacologyQ1943386
P1476titleCanonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms
P478volume83

Reverse relations

cites work (P2860)
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