Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory

scientific article published on 8 August 2017

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15252/EMBJ.201696369
P932PMC publication ID5599800
P698PubMed publication ID28790178

P50authorHerbert SchweglerQ75157334
Marc FreichelQ90178430
Rolf SprengelQ41824533
Veit FlockerziQ56384346
P2093author name stringAlexander Dietrich
Yvonne Schwarz
Andreas Draguhn
Bernd Fakler
Georg Köhr
Martin Both
Ilka Mathar
Dieter Bruns
Alan Lai
Vivan Nguyen Chi
Jörg Pohle
Raul Guzman
Petra Weißgerber
Astrid Kollewe
Barbara Schindeldecker
Jenny Bröker-Lai
P2860cites workCorticolimbic expression of TRPC4 and TRPC5 channels in the rodent brainQ21092250
Subunit composition of mammalian transient receptor potential channels in living cellsQ24530559
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyQ24623493
Essential role for TRPC5 in amygdala function and fear-related behavior.Q24657938
Calcium-sensing mechanism in TRPC5 channels contributing to retardation of neurite outgrowthQ24683953
Fluoride and arsenic exposure impairs learning and memory and decreases mGluR5 expression in the hippocampus and cortex in ratsQ27335136
TRPC5 is a regulator of hippocampal neurite length and growth cone morphologyQ28186910
SNARE function analyzed in synaptobrevin/VAMP knockout miceQ28203549
The TRP channels, a remarkably functional familyQ28206986
Memory formation: the sequence of biochemical events in the hippocampus and its connection to activity in other brain structuresQ28256467
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5Q28282369
Subregion- and cell type-restricted gene knockout in mouse brainQ28300369
The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memoryQ28300376
A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-AQ28513233
Formation of novel TRPC channels by complex subunit interactions in embryonic brainQ28568573
Transient receptor potential canonical 5 channels activate Ca2+/calmodulin kinase Igamma to promote axon formation in hippocampal neuronsQ28579070
Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1Q28582069
Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1Q28587996
Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation inductionQ28590701
Place navigation impaired in rats with hippocampal lesionsQ29547869
Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.Q30431334
Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learningQ30494493
Melanopsin signalling in mammalian iris and retinaQ30504582
TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channelQ30593487
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- miceQ31929609
Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategiesQ33440592
TRPC5 is a Ca2+-activated channel functionally coupled to Ca2+-selective ion channelsQ33553594
Silent synapses and the emergence of a postsynaptic mechanism for LTP.Q33641298
Use of an eight-arm radial water maze to assess working and reference memory following neonatal brain injuryQ33647982
mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learningQ33908562
NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cellsQ34249319
Synaptic plasticity, memory and the hippocampus: a neural network approach to causality.Q34727978
Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibilityQ34768889
Extending the dynamic range of label-free mass spectrometric quantification of affinity purificationsQ35751621
Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegenerationQ35776768
The value of spontaneous alternation behavior (SAB) as a test of retention in pharmacological investigations of memoryQ35909381
Spatial memory impairment by TRPC1 depletion is ameliorated by environmental enrichmentQ35976149
A Tradeoff Between Accuracy and Flexibility in a Working Memory Circuit Endowed with Slow Feedback MechanismsQ36098754
Functional role of TRPC proteins in native systems: implications from knockout and knock-down studies.Q36173605
Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's diseaseQ36276521
Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanismsQ36573164
Effect of Food Deprivation on a Delayed Nonmatch-to-place T-maze TaskQ36976849
Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze taskQ37068546
Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneuronsQ37088610
TRPC3 channels are required for synaptic transmission and motor coordinationQ37099115
Enhanced long-term and impaired short-term spatial memory in GluA1 AMPA receptor subunit knockout mice: evidence for a dual-process memory modelQ37246175
Heteromeric TRPV4-C1 channels contribute to store-operated Ca(2+) entry in vascular endothelial cellsQ37283364
The role of hippocampal GluR1 and GluR2 receptors in manic-like behaviorQ37391006
Spatial memory, recognition memory, and the hippocampusQ37569665
Excitatory and inhibitory autaptic currents in isolated hippocampal neurons maintained in cell cultureQ37588622
The interplay between the intestinal microbiota and the brainQ38045736
A specific role for group I mGluRs in hippocampal LTP and hippocampus-dependent spatial learningQ40416157
Selective association of TRPC channel subunits in rat brain synaptosomesQ40697831
Transient receptor potential channel 1 (TRPC1) reduces calcium permeability in heteromeric channel complexesQ40811040
TRPC1 and TRPC5 form a novel cation channel in mammalian brain.Q40812989
Metabotropic glutamate receptors in hippocampal long-term potentiation and learning and memoryQ41059624
Dissecting spatial knowledge from spatial choice by hippocampal NMDA receptor deletionQ41944017
Neurobehavioral Anomalies in the Pitx3/ak Murine Model of Parkinson's Disease and MPTP.Q42483926
Intracellular calcium strongly potentiates agonist-activated TRPC5 channels.Q42548715
NMDA receptor ablation on parvalbumin-positive interneurons impairs hippocampal synchrony, spatial representations, and working memoryQ42839853
SNARE force synchronizes synaptic vesicle fusion and controls the kinetics of quantal synaptic transmissionQ42946194
Behavioral characterization of CD36 knockout mice with SHIRPA primary screenQ43342079
Global slowing of network oscillations in mouse neocortex by diazepam.Q43740648
Effects of cytotoxic hippocampal lesions in mice on a cognitive test batteryQ44016881
Spatial memory dissociations in mice lacking GluR1.Q44114033
Regional differences in distribution and functional expression of small-conductance Ca2+-activated K+ channels in rat brain.Q44213481
Activity-dependent modulation of the rate at which synaptic vesicles become available to undergo exocytosisQ44475245
Restoration of spatial working memory by genetic rescue of GluR-A-deficient miceQ45276212
Regional diversity and developmental dynamics of the AMPA-receptor proteome in the mammalian brain.Q45803143
NMDA receptor subunit NR2A is required for rapidly acquired spatial working memory but not incremental spatial reference memory.Q46667155
Synaptic activation of transient receptor potential channels by metabotropic glutamate receptors in the lateral amygdalaQ46805670
High-frequency firing helps replenish the readily releasable pool of synaptic vesiclesQ47741527
Hippocampal synaptic plasticity, spatial memory and anxietyQ47914550
PI3Kγ is required for NMDA receptor-dependent long-term depression and behavioral flexibilityQ48034381
TRPC6 inhibited NMDA current in cultured hippocampal neuronsQ48125553
Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learningQ48189640
Theta phase modulates multiple layer-specific oscillations in the CA1 region.Q48274307
Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behaviorQ48274810
Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics.Q48276818
Allocentric spatial learning by hippocampectomised rats: a further test of the "spatial mapping" and "working memory" theories of hippocampal function.Q48278392
Assessment of spatial memory using the T mazeQ48347939
The effects of hippocampal lesions upon spatial and non-spatial tests of working memoryQ48378274
Calcium dependence and recovery kinetics of presynaptic depression at the climbing fiber to Purkinje cell synapse.Q48414600
Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signalingQ48461386
A TRPC1-mediated increase in store-operated Ca2+ entry is required for the proliferation of adult hippocampal neural progenitor cells.Q48517520
Gamma oscillations in the entorhinal cortex of the freely behaving rat.Q48558749
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor.Q48974444
Activation of TRPC4β by Gαi subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuronQ49066474
Generalized estimating equations. Notes on the choice of the working correlation matrix.Q50666126
5-HT1B receptor knock-out mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze.Q51089098
Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task.Q51106169
Distinct components of spatial learning revealed by prior training and NMDA receptor blockade.Q52050936
Different forms of LTD in the CA1 region of the hippocampus: role of age and stimulus protocol.Q52171370
Excitotoxic hippocampal lesions disrupt allocentric spatial learning in mice: effects of strain and task demands.Q52172549
Ibotenate Lesions of Hippocampus and/or Subiculum: Dissociating Components of Allocentric Spatial Learning.Q52242628
C-Terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptorsQ73870745
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)2770-2789
P577publication date2017-08-08
P1433published inThe EMBO JournalQ1278554
P1476titleHeteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory
P478volume36

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cites work (P2860)
Q57074815Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory
Q89511103Angiotensin-II-Evoked Ca2+ Entry in Murine Cardiac Fibroblasts Does Not Depend on TRPC Channels
Q91790718Canonical Transient Receptor Potential (TRPC) Channels in Nociception and Pathological Pain
Q88645885Cryo-EM structure of the cytoplasmic domain of murine transient receptor potential cation channel subfamily C member 6 (TRPC6)
Q61796735Differential PI(4,5)P sensitivities of TRPC4, C5 homomeric and TRPC1/4, C1/5 heteromeric channels
Q58782920Dual action of the Gα-PLCβ-PI(4,5)P pathway on TRPC1/4 and TRPC1/5 heterotetramers
Q95840757Evidence of a Role for the TRPC Subfamily in Mediating Oxidative Stress in Parkinson's Disease
Q90210582Evolution of acid nociception: ion channels and receptors for detecting acid
Q102369456Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site
Q89598406Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells
Q91635236Novel Targets for Stroke Therapy: Special Focus on TRPC Channels and TRPC6
Q55606266Patient-Specific iPSC-Based Models of Huntington’s Disease as a Tool to Study Store-Operated Calcium Entry Drug Targeting.
Q58801731Permeation and Rectification in Canonical Transient Receptor Potential-6 (TRPC6) Channels
Q91655002Potent, selective, and subunit-dependent activation of TRPC5 channels by a xanthine derivative
Q91704583Pre- and post-synaptic roles for DCC in memory consolidation in the adult mouse hippocampus
Q94461672RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways
Q55476743Remarkable Progress with Small-Molecule Modulation of TRPC1/4/5 Channels: Implications for Understanding the Channels in Health and Disease.
Q49886784Renal physiology: TRPC5 inhibition to treat progressive kidney disease.
Q57450480Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating
Q91829563Switching between persistent firing and depolarization block in individual rat CA1 pyramidal neurons
Q97894561Synthesis and Characterization of a Specific Iodine-125 Labeled TRPC5 Radioligand
Q94464151TRP Channels as Emerging Therapeutic Targets for Neurodegenerative Diseases
Q92636542TRPC Channels: Dysregulation and Ca2+ Mishandling in Ischemic Heart Disease
Q90010676TRPC channels are not required for graded persistent activity in entorhinal cortex neurons
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Q89468002TRPC channels: Structure, function, regulation and recent advances in small molecular probes
Q49659975TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation
Q55309338TRPC1 Channels Are Expressed in Pyramidal Neurons and in a Subset of Somatostatin Interneurons in the Rat Neocortex.
Q89834740TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons
Q93036173TRPC1 mediates slow excitatory synaptic transmission in hippocampal oriens/alveus interneurons
Q89659079The Role of TRPC1 in Modulating Cancer Progression
Q64275717The Role of Transient Receptor Potential (TRP) Channels in the Transduction of Dental Pain
Q58565607The TRPC5 channel regulates angiogenesis and promotes recovery from ischemic injury in mice
Q91721563Trpc5 deficiency causes hypoprolactinemia and altered function of oscillatory dopamine neurons in the arcuate nucleus

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