Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription

scientific article published on June 1997

Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P932PMC publication ID232608
P698PubMed publication ID9184011

P2093author name stringT Kogoma
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The recombination hot spot chi activates RecBCD recombination by converting Escherichia coli to a recD mutant phenocopyQ24563863
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Autodigestion of lexA and phage lambda repressorsQ24597460
recD: the gene for an essential third subunit of exonuclease VQ24630457
Biochemistry of homologous recombination in Escherichia coliQ24634614
Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomesQ24635818
DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progressionQ27933115
The repair of double-strand breaks in DNA; a model involving recombinationQ28256950
The double-strand-break repair model for recombinationQ28267259
Mapping and sequencing of mutations in the Escherichia colirpoB gene that lead to rifampicin resistanceQ29395941
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitorQ29547710
Genetic separation of Escherichia coli recA functions for SOS mutagenesis and repressor cleavage.Q30380797
RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activationQ33559704
Adaptive mutation sequences reproduced by mismatch repair deficiencyQ33640315
DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coliQ33825068
Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coliQ33849909
UV-induced alleviation of K-specific restriction of bacteriophage lambdaQ37503901
Footprinting analysis of mammalian RNA polymerase II along its transcript: an alternative view of transcription elongationQ37511357
Ribonucleases H of retroviral and cellular originQ37563457
Involvement of the activated form of RecA protein in SOS mutagenesis and stable DNA replication in Escherichia coliQ37579186
Absence of RNase H allows replication of pBR322 in Escherichia coli mutants lacking DNA polymerase IQ37580451
A new class of Escherichia coli recBC mutants: implications for the role of RecBC enzyme in homologous recombinationQ37580459
Mechanism of ultraviolet-induced mutagenesis: Extent and fidelity of in vitro DNA synthesis on irradiated templatesQ37589566
Conjugational recombination in E. coli: myths and mechanismsQ37623662
Escherichia coli PriA protein is essential for inducible and constitutive stable DNA replicationQ37638403
Escherichia coli RecG and RecA proteins in R-loop formation.Q37697599
Mutation induced by DNA damage: a many protein affairQ37892175
Ribonuclease H: from discovery to 3D structureQ37903282
Branch migration of Holliday junctions: identification of RecG protein as a junction specific DNA helicaseQ38302894
A mutation in helicase motif III of E. coli RecG protein abolishes branch migration of Holliday junctionsQ38311217
Homologous pairing in vitro stimulated by the recombination Hotspot, ChiQ38334215
Interactions between RuvA and RuvC at Holliday junctions: inhibition of junction cleavage and formation of a RuvA-RuvC-DNA complex.Q38350438
DNA synthesis inhibition and the induction of protein X in Escherichia coliQ39376375
DNA double-chain breaks in recombination of phage lambda and of yeastQ39489899
Selective inhibition of in vitro DNA synthesis dependent on phiX174 compared with fd DNA. I. Protein requirements for selective inhibitionQ39811802
The RuvABC proteins and Holliday junction processing in Escherichia coliQ39840417
Modulation of recombination and DNA repair by the RecG and PriA helicases of Escherichia coli K-12.Q39843576
Orientation-dependent recombination hotspot activity in bacteriophage λQ39902694
Evidence that recBC-dependent degradation of duplex DNA in Escherichia coli recD mutants involves DNA unwindingQ39935833
Inhibition of the recBCD-dependent activation of Chi recombinational hot spots in SOS-induced cells of Escherichia coliQ39935949
Requirement of the Escherichia coli dnaA gene function for ori-2-dependent mini-F plasmid replicationQ39956426
RecA protein acts at the initiation of stable DNA replication in rnh mutants of Escherichia coli K-12.Q39980927
Conditional Lethality of recA and recB Derivatives of a Strain of Escherichia coli K-12 with a Temperature-Sensitive Deoxyribonucleic Acid Polymerase IQ40098137
Replication of animal mitochondrial DNA.Q40103664
Does transcription by RNA polymerase play a direct role in the initiation of replication?Q40394500
Collapse and repair of replication forks in Escherichia coliQ40416038
Molecular mechanisms of Holliday junction processing in Escherichia coli.Q40454068
Instability of inhibited replication forks in E. coli.Q40475161
Multiple initiation mechanisms adapt phage T4 DNA replication to physiological changes during T4's developmentQ40479098
Discriminatory function of ribonuclease H in the selective initiation of plasmid DNA replicationQ40492742
Old phage, new insights: two recently recognized mechanisms of transcriptional regulation in bacteriophage T4 developmentQ40521989
RNA-DNA hybridization promoted by E. coli RecA proteinQ40533798
RecA protein promotes rapid RNA-DNA hybridization in heterogeneous RNA mixturesQ40533804
DNA repair comes of age.Q40609470
Chi and the RecBC D enzyme of Escherichia coliQ40614043
Mechanisms of transcription-repair coupling and mutation frequency declineQ40693785
The initiator protein DnaA: evolution, properties and functionQ40716275
Reaching for the ring: the study of mitochondrial genome structureQ40786608
Chi sites in combination with RecA protein increase the survival of linear DNA in Escherichia coli by inactivating exoV activity of RecBCD nucleaseQ40792215
Repair of DNA double-strand breaks in Escherichia coli, which requires recA function and the presence of a duplicate genomeQ40840136
Survival of hunger and stress: the role of rpoS in early stationary phase gene regulation in E. coliQ40871460
Dissociation of synthetic Holliday junctions by E. coli RecG protein.Q40871651
A novel Escherichia coli mutant capable of DNA replication in the absence of protein synthesisQ40901690
A cold sensitive dnaA mutant of E. coli which overinitiates chromosome replication at low temperatureQ40913729
Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.Q40925823
Homologous recombination and the roles of double-strand breaksQ40930013
Cloning of replication origins from the E. coli K12 chromosomeQ40936760
ATP-dependent resolution of R-loops at the ColE1 replication origin by Escherichia coli RecG protein, a Holliday junction-specific helicaseQ33885962
The origin of replication, oriC, and the dnaA protein are dispensable in stable DNA replication (sdrA) mutants of Escherichia coli K-12.Q33933466
DNA damage-inducible origins of DNA replication in Escherichia coliQ33938542
Double-stranded gap repair of DNA by gene conversion in Escherichia coliQ33954364
Further tests of a recombination model in which chi removes the RecD subunit from the RecBCD enzyme of Escherichia coliQ33957092
Adaptive reversion of a frameshift mutation in Escherichia coliQ33958142
Roles of ruvA, ruvC and recG gene functions in normal and DNA damage-inducible replication of the Escherichia coli chromosomeQ33963364
DNA synthesis errors associated with double-strand-break repairQ33965497
Two enzymes, both of which process recombination intermediates, have opposite effects on adaptive mutation in Escherichia coli.Q33966542
Opposing roles of the holliday junction processing systems of Escherichia coli in recombination-dependent adaptive mutationQ33966750
Differential suppression of priA2::kan phenotypes in Escherichia coli K-12 by mutations in priA, lexA, and dnaCQ33967442
Repair of double-strand breaks in bacteriophage T4 by a mechanism that involves extensive DNA replicationQ33968071
Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli.Q34019746
Homologous recombination-dependent initiation of DNA replication from DNA damage-inducible origins in Escherichia coliQ34057928
DNA polymerase III holoenzyme: structure and function of a chromosomal replicating machineQ34058015
The Escherichia coli polB gene, which encodes DNA polymerase II, is regulated by the SOS systemQ34144983
DNA synthesis dependent on genetic recombination: characterization of a reaction catalyzed by purified bacteriophage T4 proteinsQ34162674
RecBC enzyme nicking at Chi sites during DNA unwinding: location and orientation-dependence of the cuttingQ34193611
DNA Sequence and Analysis of 136 Kilobases of the Escherichia coli Genome: Organizational Symmetry around the Origin of ReplicationQ34306353
Thymine starvation-induced structural changes in Escherichia coli DNA. Detection by pulsed field gel electrophoresis and evidence for involvement of homologous recombinationQ34326137
DNA replication triggered by double-stranded breaks in E. coli: dependence on homologous recombination functionsQ34336035
Hypernegative supercoiling of the DNA template during transcription elongation in vitro.Q34348708
Recovery from ultraviolet light-induced inhibition of DNA synthesis requires umuDC gene products in recA718 mutant strains but not in recA+ strains of Escherichia coliQ34349964
The recombination hotspot chi is a regulatory sequence that acts by attenuating the nuclease activity of the E. coli RecBCD enzymeQ34355622
Overexpression of RNase H partially complements the growth defect of an Escherichia coli delta topA mutant: R-loop formation is a major problem in the absence of DNA topoisomerase IQ34451557
In vivo evidence for the involvement of anionic phospholipids in initiation of DNA replication in Escherichia coliQ34731920
DNA sequences at immunoglobulin switch region recombination sitesQ34963864
Repair of DNA double-strand breaks in Escherichia coli cells requires synthesis of proteins that can be induced by UV lightQ35375254
Movement and site selection for priming by the primosome in phage phi X174 DNA replicationQ35413339
Purification of ribonuclease H as a factor required for initiation of in vitro Co1E1 DNA replicationQ35531732
Homologous pairing of single-stranded DNA and superhelical double-stranded DNA catalyzed by RecO protein from Escherichia coliQ35578243
Cloning of the Escherichia coli gene for primosomal protein i: the relationship to dnaT, essential for chromosomal DNA replicationQ35592174
The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repairQ35603171
Host participation in plasmid maintenance: dependence upon dnaA of replicons derived from P1 and FQ35611641
Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switchQ36776415
Termination efficiency at rho-dependent terminators depends on kinetic coupling between RNA polymerase and rhoQ36841147
The DnaA box R4 in the minimaloriCis dispensable for initiation ofEscherichia colichromosome replicationQ36890885
Recombination-dependent concatemeric plasmid replicationQ36930470
Homologous recombination in procaryotes.Q37054728
Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coliQ37060983
Fidelity mechanisms in DNA replicationQ37285267
Purified Escherichia coli recA protein catalyzes homologous pairing of superhelical DNA and single-stranded fragmentsQ37326507
Initiation of general recombination catalyzed in vitro by the recA protein of Escherichia coliQ37332515
Chi sequence protects against RecBCD degradation of DNA in vivoQ37349738
Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymesQ37402708
Replication deficiencies in priA mutants of Escherichia coli lacking the primosomal replication n' proteinQ37473720
Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replicationQ37490114
Escherichia coli XerC recombinase is required for chromosomal segregation at cell division.Q54693462
Nature of the SOS-inducing signal in Escherichia coli. The involvement of DNA replication.Q54716069
Recombination of bacteriophage lambda in recD mutants of Escherichia coli.Q54736666
Apparent gene conversion in an Escherichia coli rec+ strain is explained by multiple rounds of reciprocal crossing-over.Q54748030
Integrative suppression of dnaA(Ts) mutations mediated by plasmid F in Escherichia coli is a DnaA-dependent process.Q54758591
Effects of modulation of RNase H production on the recovery of DNA synthesis following UV-irradiation in Escherichia coli.Q54760952
Meiosis-induced double-strand break sites determined by yeast chromatin structureQ58486296
recA-independent general genetic recombination of plasmidsQ59065794
Double-strand breaks at an initiation site for meiotic gene conversionQ59068287
Intron mobility in phage T4 occurs in the context of recombination-dependent DNA replication by way of multiple pathwaysQ64389435
Quantitation of the involvement of the recA, recB, recC, recF, recJ, recN, lexA, radA, radB, uvrD, and umuC genes in the repair of X-ray-induced DNA double-strand breaks in Escherichia coliQ64390411
Double-strand scission of DNA involved in thymineless death of Escherichia coli 15 TAUQ64390846
Characterization of the replication of Escherichia coli DNA in the absence of protein synthesis: Stable DNA replicationQ66896811
The dnaA gene product is not required during stable chromosome replication in Escherichia coliQ67269746
Rec-mediated recombinational activity of two adjacent Chi elements in bacteriophage lambdaQ67288470
Stability and Properties of Double and Triple Helices: Dramatic Effects of RNA or DNA Backbone CompositionQ67464150
Two types of temperature sensitivity in DNA replication of an Escherichia coli dnaB mutantQ67488224
Inducible stable DNA replication in Escherichia coli uvr+ and uvr- cells, treated with genotoxic chemicalsQ67532245
A mechanism of formation of a persistent hybrid between elongating RNA and template DNAQ67664935
Studies on the Inducible Inhibitor of Radiation-Induced DNA Degradation of Escherichia coliQ69284084
Genetic analysis of constitutive stable DNA replication in rnh mutants of Escherichia coli K12Q69810149
Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiationQ69833258
Initiation of lagging-strand synthesis for pBR322 plasmid DNA replication in vitro is dependent on primosomal protein i encoded by dnaTQ69838760
Mechanism of transient inhibition of DNA synthesis in ultraviolet-irradiated E. coli: inhibition is independent of recA whilst recovery requires RecA protein itself and an additional, inducible SOS functionQ69893640
n' Protein activator sites of plasmid pBR322 are not essential for its DNA replicationQ70154494
Reduced transcription of the rnh gene in Escherichia coli mutants expressing the SOS regulon constitutivelyQ70176547
oriX: a new replication origin in E. coliQ70183896
Multiple origin usage for DNA replication in sdrA(rnh) mutants of Escherichia coli K-12. Initiation in the absence of oriCQ70390149
Structural analysis of mitochondrial DNA molecules from fungi and plants using moving pictures and pulsed-field gel electrophoresisQ70918189
Suppressor mutations (rin) that specifically suppress the recA+ dependence of stable DNA replication in Escherichia coliK-12Q71464922
Activation of stable DNA replication in rapidly growing Escherichia coli at the time of entry to stationary phaseQ71713399
RNase H-defective mutants of Escherichia coli: a possible discriminatory role of RNase H in initiation of DNA replicationQ72398741
dnaA suppressor (dasF) mutants of Escherichia coli are stable DNA replication (sdrA/rnh) mutantsQ72398795
Genetic control of damage-inducible restriction alleviation in Escherichia coli K12: an SOS function not repressed by lexAQ72409402
Continuous synthesis of the dnaA gene product of Escherichia coli in the cell cycleQ72945444
MECHANISM OF RNA POLYMERASE ACTION: FORMATION OF DNA-RNA HYBRIDS WITH SINGLE-STRANDED TEMPLATESQ76742714
INDUCTION OF REPLICATION BY THYMINE STARVATION AT THE CHROMOSOME ORIGIN IN ESCHERICHIA COLIQ76936164
Thymine deficiency and the normal DNA replication cycle. IQ79064176
Recombination by replicationQ40996441
Molecular handles on adaptive mutationQ41034482
Origin of Replication, oriC, of the Escherichia coli K12 Chromosome: Genetic Mapping and Minichromosome ReplicationQ41094802
recA-Dependent DNA Replication in the Absence of Protein Synthesis: Characteristics of a Dominant Lethal Replication Mutation, dnaT, and Requirement for recA+ FunctionQ41094857
Initiation of V(D)J recombinations in a cell-free system by RAG1 and RAG2 proteins.Q41096610
Processing the holliday junction in homologous recombinationQ41178364
Induction of UV-resistant DNA replication in Escherichia coli: Induced stable DNA replication as an SOS functionQ41180656
Size and Structure of Replicating Mitochondrial DNA in Cultured Tobacco CellsQ41218627
Adaptive reversion of a frameshift mutation in Escherichia coli by simple base deletions in homopolymeric runsQ41572901
Function of ribonuclease H in initiation of DNA replication in Escherichia coli K-12.Q41866211
Effect on DNA topology by DnaA protein, the initiation factor of chromosomal DNA replication in Escherichia coliQ41930143
The mechanism of recA polA lethality: suppression by RecA-independent recombination repair activated by the lexA(Def) mutation in Escherichia coliQ42965480
Roles of DNA topoisomerases in the regulation of R-loop formation in vitroQ43485153
Transcriptional activation of pBR322 DNA can lead to duplex DNA unwinding catalyzed by the Escherichia coli preprimosome.Q43505873
Rec-mediated recombinational hot spot activity in bacteriophage lambda. III. Chi mutations are site-mutations stimulating rec-mediated recombinationQ43933897
Concatemer formation of ColE1-type plasmids in mutants of Escherichia coli lacking RNase H activityQ44101314
Activation of recA protein. The open helix model for LexA cleavageQ44689911
Attachment of nascent RNA molecules to superhelical DNAQ45140620
Purification and characterization of bacteriophage T4 gene 59 protein. A DNA helicase assembly protein involved in DNA replication.Q46080119
The mutant DnaAcos protein which overinitiates replication of the Escherichia coli chromosome is inert to negative regulation for initiationQ46182018
DnaA protein is sensitive to a soluble factor and is specifically inactivated for initiation of in vitro replication of the Escherichia coli minichromosome.Q46611669
Operon structure of dnaT and dnaC genes essential for normal and stable DNA replication of Escherichia coli chromosomeQ46750150
Sequential early stages in the in vitro initiation of replication at the origin of the Escherichia coli chromosomeQ46911724
Induction of chromosome re-initiations in a thermosensitive DNA mutant of EscherichiacoliQ47763712
DNA replication in Escherichia coli: Replication in absence of protein synthesis after replication inhibitionQ47763722
Changes of Membrane Proteins and Their Relation to Deoxyribonucleic Acid Synthesis and Cell Division of Escherichia coliQ47767106
dif, a recA-independent recombination site in the terminus region of the chromosome of Escherichia coliQ48217431
Inviability of recA- derivatives of the DNA polymerase mutant of De Lucia and Cairns.Q53965970
Stimulation of nuclease activity by thymine starvationQ54344341
Effects of rifampicin resistant rpoB mutations on antitermination and interaction with nusA in Escherichia coli.Q54373152
Evidence for the direct involvement of RNA in the initiation of DNA replication in Escherichia coli 15T−Q54392394
Growth-medium-dependent repair of DNA single-strand and double-strand breaks in X-irradiated Escherichia coli.Q54443508
Initiation of DNA replication in Escherichia coli: RNase H-deficient mutants do not require the dnaA functionQ54485264
Repair of DNA double-strand breaks in Escherichia coli K12 requires a functional recN productQ54485834
Integration of donor DNA in bacterial conjugationQ54531196
The RecG branch migration protein of Escherichia coli dissociates R-loops.Q54575363
Inducible stable DNA replication of Escherichia coli tolerates unexcised pyrimidine dimers in an uvr-dependent manner.Q54621641
RecA, Tus protein and constitutive stable DNA replication in Escherichia coli rnhA mutants.Q54627661
Adaptive mutation by deletions in small mononucleotide repeats.Q54630365
Structural requirements of substrate DNA for binding to and cleavage by RuvC, a Holliday junction resolvase.Q54633147
Recombination in adaptive mutation.Q54635736
Substrate specificity of the Escherichia coli RuvC protein. Resolution of three- and four-stranded recombination intermediates.Q54640001
DNA damage-inducible replication of the Escherichia coli chromosome is initiated at separable sites within the minimal oriC.Q54640687
Two related recombinases are required for site-specific recombination at dif and cer in E. coli K12.Q54649603
Reverse branch migration of Holliday junctions by RecG protein: a new mechanism for resolution of intermediates in recombination and DNA repair.Q54649605
Requirement of homologous recombination functions for viability of the Escherichia coli cell that lacks RNase HI and exonuclease V activities.Q54664457
ATPase-deficient mutants of the Escherichia coli DNA replication protein PriA are capable of catalyzing the assembly of active primosomesQ54680730
Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coliQ54684426
Growth phase-dependent modification of RNA polymerase in Escherichia coliQ54689764
DNA polymerase I in constitutive stable DNA replication in Escherichia coliQ35621299
Recombination associated with replication of malarial mitochondrial DNAQ35844667
Identification and characterization of the Escherichia coli RecT protein, a protein encoded by the recE region that promotes renaturation of homologous single-stranded DNAQ35965992
Genetic analysis of double-strand break repair in Escherichia coliQ36104167
Escherichia coli RNA polymerase mutants that enhance or diminish the SOS response constitutively expressed in the absence of RNase HI activityQ36105787
D-loops and R-loops: alternative mechanisms for the initiation of chromosome replication in Escherichia coliQ36106189
Absence of a direct role for RNase HI in initiation of DNA replication at the oriC site on the Escherichia coli chromosomeQ36123190
Requirement for the polymerization and 5'-->3' exonuclease activities of DNA polymerase I in initiation of DNA replication at oriK sites in the absence of RecA in Escherichia coli rnhA mutantsQ36123822
Levels of epsilon, an essential replication subunit of Escherichia coli DNA polymerase III, are controlled by heat shock proteinsQ36135582
DNA polymerase I modulates inducible stable DNA replication in Escherichia coliQ36140687
Is RecF a DNA replication protein?Q36152798
Requirement of RecBC enzyme and an elevated level of activated RecA for induced stable DNA replication in Escherichia coliQ36159839
Molecular organization and nucleotide sequence of the recG locus of Escherichia coli K-12.Q36164197
RecA protein of Escherichia coli has a third essential role in SOS mutator activityQ36164939
Constitutive expression of the SOS response in recA718 mutants of Escherichia coli requires amplification of RecA718 proteinQ36228865
Mode of initiation of constitutive stable DNA replication in RNase H-defective mutants of Escherichia coli K-12.Q36238573
RNase H confers specificity in the dnaA-dependent initiation of replication at the unique origin of the Escherichia coli chromosome in vivo and in vitroQ36248894
Requirement of the Escherichia coli dnaA gene product for plasmid F maintenanceQ36259197
RNase H is not involved in the induction of stable DNA replication in Escherichia coliQ36281205
RNase H-defective mutants of Escherichia coliQ36284480
Direct evidence for specific binding of the replicative origin of the Escherichia coli chromosome to the membraneQ36299273
Method for determining whether a gene of Escherichia coli is essential: application to the polA geneQ36300382
Genetic analysis of mutations that compensate for loss of Escherichia coli DNA topoisomerase IQ36305789
Mechanisms for recF-dependent and recB-dependent pathways of postreplication repair in UV-irradiated Escherichia coli uvrBQ36333409
dnaT, dominant conditional-lethal mutation affecting DNA replication in Escherichia coliQ36342336
Evidence for RecA protein association with the cell membrane and for changes in the levels of major outer membrane proteins in SOS-induced Escherichia coli cellsQ36365196
Chi activity during transduction-associated recombinationQ36379670
Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease HQ36386816
Cleavage of the Escherichia coli lexA protein by the recA proteaseQ36392308
Targeting of the UmuD, UmuD', and MucA' mutagenesis proteins to DNA by RecA proteinQ36514563
Colibri: a functional data base for the Escherichia coli genomeQ36756440
Enzymatic production of deoxyribonucleic acid double-strand breaks after ultraviolet irradiation of Escherichia coli K-12Q36762196
The leucine-Lrp regulon in E. coli: A global response in search of a raison d'ÊtreQ36776311
P433issue2
P304page(s)212-238
P577publication date1997-06-01
P1433published inMicrobiology and Molecular Biology ReviewsQ6839270
P1476titleStable DNA replication: interplay between DNA replication, homologous recombination, and transcription
P478volume61

Reverse relations

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Q34271071Impairment of lagging strand synthesis triggers the formation of a RuvABC substrate at replication forks
Q41062317Initiation of heat-induced replication requires DnaA and the L-13-mer of oriC
Q35860818Interaction with Single-stranded DNA-binding Protein Stimulates Escherichia coli Ribonuclease HI Enzymatic Activity
Q39798255Interplay between type 1A topoisomerases and gyrase in chromosome segregation in Escherichia coli.
Q39618653Involvement of RAD9-dependent damage checkpoint control in arrest of cell cycle, induction of cell death, and chromosome instability caused by defects in origin recognition complex in Saccharomyces cerevisiae
Q40211080Isolation of SOS constitutive mutants of Escherichia coli
Q89899831Laboratory Evolution Experiments Help Identify a Predominant Region of Constitutive Stable DNA Replication Initiation
Q40684824Lambda gpP-DnaB Helicase Sequestration and gpP-RpoB Associated Effects: On Screens for Auxotrophs, Selection for Rif(R), Toxicity, Mutagenicity, Plasmid Curing.
Q33885431Links between replication, recombination and genome instability in eukaryotes
Q37696954Maintaining genome stability at the replication fork
Q52729392Maintenance of genome stability: the unifying role of interconnections between the DNA damage response and RNA-processing pathways.
Q35636113Mechanisms of Theta Plasmid Replication.
Q47334226Mechanisms of bacterial DNA replication restart.
Q33692291Mechanisms of mutation in nondividing cells. Insights from the study of adaptive mutation in Escherichia coli
Q34311682Meiotic recombination and chromosome segregation in Schizosaccharomyces pombe
Q41340163Modes of overinitiation, dnaA gene expression, and inhibition of cell division in a novel cold-sensitive hda mutant of Escherichia coli
Q39693158Modulation of DNA repair by mutations flanking the DNA channel through RNA polymerase
Q24548535Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
Q35870700Multiple pathways process stalled replication forks
Q27934618Mutations in DNA replication genes reduce yeast life span
Q38993930Nascent Connections: R-Loops and Chromatin Patterning
Q46933685New approaches to the problem of generating coherent, reproducible phenotypes
Q39109316Non-Canonical Replication Initiation: You're Fired!
Q34175610On the viability of Escherichia coli cells lacking DNA topoisomerase I
Q24555124Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells
Q47558874Oxygen and RNA in stress-induced mutation.
Q41859747Pathological replication in cells lacking RecG DNA translocase
Q24798568Phage annealing proteins promote oligonucleotide-directed mutagenesis in Escherichia coli and mouse ES cells
Q34030676Preferential cleavage of plasmid-based R-loops and D-loops by Drosophila topoisomerase IIIbeta
Q40587137Promoting and avoiding recombination: contrasting activities of the Escherichia coli RuvABC Holliday junction resolvase and RecG DNA translocase
Q42995678Purification and characterization of a novel human acidic nuclease/intra-cyclobutyl-pyrimidine-dimer-DNA phosphodiesterase
Q36008202Quantitative genomic analysis of RecA protein binding during DNA double-strand break repair reveals RecBCD action in vivo
Q38586926R loops: new modulators of genome dynamics and function
Q39647468R-loop-dependent rolling-circle replication and a new model for DNA concatemer resolution by mitochondrial plasmid mp1.
Q40009006R-loops and initiation of DNA replication in human cells: a missing link?
Q37025967R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli
Q38636495R-loops in bacterial transcription: their causes and consequences
Q35598590RNase HI Is Essential for Survival of Mycobacterium smegmatis
Q64389775RNase HII Saves rnhA Mutant Escherichia coli from R-Loop-Associated Chromosomal Fragmentation
Q40974663Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase
Q27931495Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes
Q35186084RecA protein-dependent R-loop formation in vitro.
Q39527474RecA-mediated rescue of Escherichia coli strains with replication forks arrested at the terminus
Q30765550RecA: Regulation and Mechanism of a Molecular Search Engine.
Q64389445RecBCD coordinates repair of two ends at a DNA double-strand break, preventing aberrant chromosome amplification
Q24650931RecBCD enzyme and the repair of double-stranded DNA breaks
Q39117161RecG controls DNA amplification at double-strand breaks and arrested replication forks
Q39728517RecG helicase activity at three- and four-strand DNA structures.
Q37014705RecG interacts directly with SSB: implications for stalled replication fork regression
Q42410405RecG protein and single-strand DNA exonucleases avoid cell lethality associated with PriA helicase activity in Escherichia coli
Q35089091Recombinase and translesion DNA polymerase decrease the speed of replication fork progression during the DNA damage response in Escherichia coli cells
Q56902268Recombination and its roles in DNA repair, cellular immortalization and cancer
Q34444668Recombination and replication.
Q64387300Recombinational DNA repair in a cellular context: a search for the homology search
Q28776226Recombinational crossroads: eukaryotic enzymes and the limits of bacterial precedents
Q29619755Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda
Q24606060Regulation of homologous recombination: Chi inactivates RecBCD enzyme by disassembly of the three subunits
Q42129547Remodeling of RecG Helicase at the DNA Replication Fork by SSB Protein
Q64100696Rep and UvrD Antagonize One Another at Stalled Replication Forks and This Is Exacerbated by SSB
Q35952270Repair of transposable phage Mu DNA insertions begins only when the E. coli replisome collides with the transpososome
Q24675453Repairing a double-strand chromosome break by homologous recombination: revisiting Robin Holliday's model
Q39188771Replication Restart in Bacteria
Q26741314Replication Termination: Containing Fork Fusion-Mediated Pathologies in Escherichia coli
Q42696576Replication fork collisions cause pathological chromosomal amplification in cells lacking RecG DNA translocase
Q42575711Replication fork reactivation in a dnaC2 mutant at non-permissive temperature in Escherichia coli
Q42010788Replication fork stalling and cell cycle arrest in UV-irradiated Escherichia coli
Q37588219Replication of the Escherichia coli chromosome in RNase HI-deficient cells: multiple initiation regions and fork dynamics.
Q42275355Replication-Transcription Conflicts Generate R-Loops that Orchestrate Bacterial Stress Survival and Pathogenesis
Q99412090Replisome bypass of transcription complexes and R-loops
Q33993970Requirement for homologous recombination functions for expression of the mutA mistranslator tRNA-induced mutator phenotype in Escherichia coli
Q42012393Requirements for replication restart proteins during constitutive stable DNA replication in Escherichia coli K-12.
Q34311622Rescue of arrested replication forks by homologous recombination
Q38134624Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes.
Q39538408Restart of DNA replication in Gram-positive bacteria: functional characterisation of the Bacillus subtilis PriA initiator
Q33770306Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40.
Q36512201Rho-dependent transcription termination is essential to prevent excessive genome-wide R-loops in Escherichia coli
Q26864225Ribonucleotides in bacterial DNA
Q36701282Role of DNA replication proteins in double-strand break-induced recombination in Saccharomyces cerevisiae
Q33805205Role of PriA in replication fork reactivation in Escherichia coli
Q30797538Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediates
Q34470485Roles of E. coli double-strand-break-repair proteins in stress-induced mutation
Q41081029Roles of PriA protein and double-strand DNA break repair functions in UV-induced restriction alleviation in Escherichia coli
Q35221111Roles of type 1A topoisomerases in genome maintenance in Escherichia coli
Q30008790SSB and the RecG DNA helicase: an intimate association to rescue a stalled replication fork
Q27935087Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes
Q40950393SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
Q40429985Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
Q34978255Specific genomic sequences of E. coli promote replicational initiation by directly reactivating ADP-DnaA.
Q40431401Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity
Q42873146Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation
Q38860416Stalled replication fork rescue requires a novel DNA helicase
Q36677142Static and Dynamic Factors Limit Chromosomal Replication Complexity in Escherichia coli, Avoiding Dangers of Runaway Overreplication
Q35626315Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference
Q89975724Supercoiling, R-loops, Replication and the Functions of Bacterial Type 1A Topoisomerases
Q33995751T7 single strand DNA binding protein but not T7 helicase is required for DNA double strand break repair
Q40781109The Arg Fingers of Key DnaA Protomers Are Oriented Inward within the Replication Origin oriC and Stimulate DnaA Subcomplexes in the Initiation Complex
Q40360421The Consequences of Replicating in the Wrong Orientation: Bacterial Chromosome Duplication without an Active Replication Origin
Q43015372The DNA Exonucleases of Escherichia coli
Q38747435The Escherichia coli Cryptic Prophage Protein YfdR Binds to DnaA and Initiation of Chromosomal Replication Is Inhibited by Overexpression of the Gene Cluster yfdQ-yfdR-yfdS-yfdT
Q37516281The Escherichia coli argU10(Ts) phenotype is caused by a reduction in the cellular level of the argU tRNA for the rare codons AGA and AGG.
Q24551864The Rad51 paralog Rad51B promotes homologous recombinational repair
Q39679859The RuvABC resolvase is indispensable for recombinational repair in sbcB15 mutants of Escherichia coli
Q34279693The Schizosaccharomyces pombe rad60 gene is essential for repairing double-strand DNA breaks spontaneously occurring during replication and induced by DNA-damaging agents.
Q35908868The Yin and Yang of R-loop biology
Q24630851The architecture of the human Rad54-DNA complex provides evidence for protein translocation along DNA
Q92023905The balancing act of R-loop biology: The good, the bad, and the ugly
Q33867563The breast cancer susceptibility gene, BRCA2: at the crossroads between DNA replication and recombination?
Q39835877The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry
Q22066232The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes
Q38540510The membrane: transertion as an organizing principle in membrane heterogeneity.
Q38257019The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores.
Q42391802The right half of the Escherichia coli replication origin is not essential for viability, but facilitates multi-forked replication
Q34446766Timely binding of IHF and Fis to DARS2 regulates ATP-DnaA production and replication initiation.
Q94464339Too Much of a Good Thing: How Ectopic DNA Replication Affects Bacterial Replication Dynamics
Q58730616Topoisomerases I and III inhibit R-loop formation to prevent unregulated replication in the chromosomal Ter region of Escherichia coli
Q38236218Transcription and recombination: when RNA meets DNA.
Q39567802Transcriptional analysis and mutation of a dnaA-like gene in Synechocystis sp. strain PCC 6803.
Q34603730Transient and heritable mutators in adaptive evolution in the lab and in nature
Q34768582Two novel PIWI families: roles in inter-genomic conflicts in bacteria and Mediator-dependent modulation of transcription in eukaryotes
Q33967896UvsW protein regulates bacteriophage T4 origin-dependent replication by unwinding R-loops
Q34235259Validation of bacterial replication termination models using simulation of genomic mutations
Q33995863Viability of rep recA mutants depends on their capacity to cope with spontaneous oxidative damage and on the DnaK chaperone protein
Q64087622Whole Proteome Clustering of 2,307 Proteobacterial Genomes Reveals Conserved Proteins and Significant Annotation Issues
Q39392218iOri-Human: identify human origin of replication by incorporating dinucleotide physicochemical properties into pseudo nucleotide composition

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